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1. 发明申请

WO2005059121A3 DOMINANT GENE SUPPRESSION TRANSGENES AND METHODS OF USING SAME 审中-公开
标题翻译：主要基因抑制转录物及其使用方法
公开(公告)号：WO2005059121A3
公开(公告)日：2006-06-01
申请号：PCT/US2004042649
申请日：2004-12-16
申请人： PIONEER HI BRED INT , CIGAN ANDREW M , FOX TIMOTHY W , HERSHEY HOWARD P , UNGER ERICA , WU YONGZHONG
发明人： CIGAN ANDREW M , FOX TIMOTHY W , HERSHEY HOWARD P , UNGER ERICA , WU YONGZHONG
IPC分类号： A01H1/00 , A01H5/00 , C12N5/14 , C12N15/63 , C12N15/82
CPC分类号： C12N15/8218 , A01H1/02 , C12N15/8212 , C12N15/8216 , C12N15/8231 , C12N15/8263 , C12N15/8287 , C12N15/8289 , C12N15/829
摘要： Pairs of plants are provided in which complementing constructs result in suppression of a parental phenotype in the progeny. Methods to generate and maintain such plants, and methods of use of said plants, are provided, including use of parental plants to produce sterile plants for hybrid seed production. Also provided are regulatory elements for pollen-preferred expression of linked polynucleotides. Also provided are methods for identifying gene function, and methods for repressing transmission of transgenes.
摘要翻译：提供了一对植物，其中补体结构导致在后代中抑制亲本表型。提供了产生和维持这种植物的方法以及所述植物的使用方法，包括使用亲本植物来生产用于杂交种子生产的无菌植物。还提供了用于花粉优选表达连接的多核苷酸的调节元件。还提供用于鉴定基因功能的方法以及抑制转基因传播的方法。

2. 发明申请

WO2008112970A3 DOMINANT GENE SUPPRESSION TRANSGENES AND METHODS OF USING SAME 审中-公开
标题翻译：主要基因抑制转录物及其使用方法
公开(公告)号：WO2008112970A3
公开(公告)日：2009-01-15
申请号：PCT/US2008056989
申请日：2008-03-14
申请人： PIONEER HI BRED INT , CIGAN ANDREW M , FOX TIM W , HERSHEY HOWARD P , UNGER ERICA , WU YONGZHONG
发明人： CIGAN ANDREW M , FOX TIM W , HERSHEY HOWARD P , UNGER ERICA , WU YONGZHONG
IPC分类号： C12N15/82 , A01H1/00
CPC分类号： C12N15/8289 , C12N15/8216 , C12N15/8241 , C12N15/829 , G01N33/5097
摘要： Pairs of plants are provided in which complementing constructs result in suppression of a parental phenotype in the progeny. Methods to generate and maintain such plants, and methods of use of said plants, are provided, including use of parental plants to produce sterile plants for hybrid seed production. Also provided are regulatory elements for pollen-preferred expression of linked polynucleotides. Also provided are methods for identifying gene function, methods for testing allelic variants, and methods for repressing transmission of transgenes.
摘要翻译：提供了一对植物，其中补体结构导致在后代中抑制亲本表型。提供了产生和维持这种植物的方法以及所述植物的使用方法，包括使用亲本植物来生产用于杂交种子生产的无菌植物。还提供了用于花粉优选表达连接的多核苷酸的调节元件。还提供了用于鉴定基因功能的方法，用于测试等位基因变体的方法以及抑制转基因传播的方法。

3. 发明申请

WO2014164961A2 MANIPULATION OF DOMINANT MALE STERILITY 审中-公开
标题翻译：优势雄性不育的调控
公开(公告)号：WO2014164961A2
公开(公告)日：2014-10-09
申请号：PCT/US2014023932
申请日：2014-03-12
申请人： PIONEER HI BRED INT , CIGAN ANDREW M
发明人： CIGAN ANDREW M
IPC分类号： C12N15/82
CPC分类号： C12N15/8289 , C07K14/415
摘要： Compositions and methods for modulating male fertility in a plant are provided. Compositions comprise nucleotide sequences, and active fragments and variants thereof, which modulate male fertility. Further provided are expression cassettes comprising the male fertility polynucleotides, or active fragments or variants thereof, operably linked to a promoter, wherein expression of the polynucleotides modulates the male fertility of a plant. Various methods are provided wherein the level and/or activity of the sequences that influence male fertility is modulated in a plant or plant part. In certain embodiments, the plant is polyploid.
摘要翻译：提供了用于调节植物雄性能力的组合物和方法。组合物包含调节雄性生育力的核苷酸序列及其活性片段和变体。还提供了包含与启动子可操作连接的雄性能育性多核苷酸或其活性片段或变体的表达盒，其中多核苷酸的表达调节植物的雄性能育性。提供了各种方法，其中影响雄性能育性的序列的水平和/或活性在植物或植物部分中被调节。在某些实施方案中，植物是多倍体。

4. 发明专利

PH12013500640A1 DOMINANT GENE SUPPRESSION TRANSGENES AND METHODS OF USING SAME 未知
公开(公告)号：PH12013500640A1
公开(公告)日：2016-01-25
申请号：PH12013500640
申请日：2013-04-03
申请人： PIONEER HI BRED INT
发明人： CIGAN ANDREW M , FOX TIM W , HERSHEY HOWARD P , ERICA UNGER , YONGZHONG WU
IPC分类号： C12N15/82 , A01H1/00
摘要： Pairs of plants are provided in which complementing constructs result in suppression of a parental phenotype in the progeny. Methods to generate and maintain such plants, and methods of use of said plants, are provided, including use of parental plants to produce sterile plants for hybrid seed production. Also provided are regulatory elements for pollen-preferred expression of linked polynucleotides. Also provided are methods for identifying gene function, methods for testing allelic variants, and methods for repressing transmission of transgenes.

5. 发明专利

BRPI0808896A2 未知
公开(公告)号：BRPI0808896A2
公开(公告)日：2014-09-02
申请号：BRPI0808896
申请日：2008-03-14
申请人： PIONEER HI BRED INT
发明人： CIGAN ANDREW M , HERSHEY HOWARD P , UNGER ERICA , WU YONGZHONG , FOX TIM W
IPC分类号： C12N15/82 , A01H1/00

6. 发明专利

PT1696721E TRANSGÉNICOS COM SUPRESSÃO DE GENE DOMINANTE E PROCESSOS PARA A SUA UTILIZAÇÃO 未知
公开(公告)号：PT1696721E
公开(公告)日：2010-05-06
申请号：PT04814790
申请日：2004-12-16
申请人： PIONEER HI BRED INT
发明人： CIGAN ANDREW M , FOX TIMOTHY W , HERSHEY HOWARD P , UNGER ERICA , WU YONGZHONG
IPC分类号： A01H1/00 , C12N5/14 , C12N15/63 , C12N15/82

7. 发明专利

NZ547957A Method of maintaining homozygous recessive condition of a first maize plant when crossed with a second maize plant 未知
公开(公告)号：NZ547957A
公开(公告)日：2009-09-25
申请号：NZ54795704
申请日：2004-12-16
申请人： PIONEER HI BRED INT
发明人： CIGAN ANDREW M , FOX TIMOTHY W , HERSHEY HOWARD P , UNGER ERICA , WU YONGZHONG
IPC分类号： A01H1/00 , A01H5/00 , C12N5/14 , C12N15/05 , C12N15/63 , C12N15/82
摘要： Disclosed is a method of maintaining the homozygous recessive condition of a first maize plant when crossing with a second maize plant, comprising (a) providing a first maize plant with a homozygous recessive genotype for male sterility; (b) providing a maintainer plant by introducing by transformation into a second maize plant, which plant prior to transformation also has a homozygous recessive genotype for male sterility, an exogenous restoring gene construct comprising (i) a first nucleotide sequence that, if introduced into the first plant, would restore the homozygous recessive trait, said first nucleotide sequence being in a hemizygous condition; and (ii) a second nucleotide sequence, linked to the first nucleotide sequence, which inhibits the formation, function, or dispersal of male gametes of the maintainer plant wherein the second nucleotide sequence is operably Iinked to a promoter preferentially directing expression in the male gametes; (c) growing the maintainer plant such that all viable pollen produced contains the recessive allele and does not contain said restoring gene construct; and (d) pollinating the first plant with the maintainer plant to produce progeny which maintain the homozygous recessive condition of the first plant.

8. 发明专利

ES2267105T3 SISTEMA GENETICO NUCLEAR REVERSIBLE PARA LA ESTERILIZACION MASCULINA DE PLANTAS TRANSGENICAS. 未知
公开(公告)号：ES2267105T3
公开(公告)日：2007-03-01
申请号：ES95940806
申请日：1995-12-07
申请人： PIONEER HI BRED INT
发明人： CIGAN ANDREW M , ALBERTSEN MARC C
IPC分类号： A01H5/00 , C12N15/82 , A01H1/02 , A01H1/06 , C07K14/415 , C12N5/10 , C12N9/10 , C12N15/05 , C12N15/09 , C12P21/02
摘要： EL DESARROLLO DE LAS PLANTAS PUEDE ALTERARSE TRANSFORMANDO UNA PLANTA CON UNA MANIPULACION GENETICA QUE INCLUYA ELEMENTOS REGULADORES Y SECUENCIAS DE ADN CAPACES DE ACTUAR INHIBIENDO LA FORMACION DE POLEN O SU FUNCION Y, POR TANTO, PRODUCIENDO UNA PLANTA MACHO REVERSIBLEMENTE ESTERIL. EN PARTICULAR, LA PRESENTE INVENCION SE REFIERE AL EMPLEO DE GENES NEGATIVOS DOMINANTES Y DE UN PROMOTOR ESPECIFICO DE LAS ANTERAS. LA ESTERILIDAD DE LA PLANTA MACHO PUEDE RECUPERARSE INCORPORANDO A LA PLANTA UN SEGUNDO FRAGMENTO DE GEN QUE REPRIMA AL GEN NEGATIVO DOMINANTE. LA INVENCION TAMBIEN SE REFIERE A NUEVAS SECUENCIAS DE ADN CON LA CAPACIDAD DE SERVIR COMO PROMOTORES ESPECIFICOS DE ANTERAS EN LAS PLANTAS.

9. 发明专利

CA2871472A1 DOMINANT GENE SUPPRESSION TRANSGENES AND METHODS OF USING SAME 未知
公开(公告)号：CA2871472A1
公开(公告)日：2005-06-30
申请号：CA2871472
申请日：2004-12-16
申请人： PIONEER HI BRED INT
发明人： CIGAN ANDREW M , FOX TIMOTHY W , HERSHEY HOWARD P , UNGER ERICA , WU YONGZHONG
IPC分类号： C12N15/113 , A01H1/00 , A01H1/02 , A01H5/00 , C12N5/04 , C12N5/10 , C12N5/14 , C12N15/63 , C12N15/82 , C12Q1/68
摘要： Pairs of plants are provided in which complementing constructs result in suppression of a parental phenotype in the progeny. Methods to generate and maintain such plants, and methods of use of said plants, are provided, including use of parental plants to produce sterile plants for hybrid seed production. Also provided are regulatory elements for pollen-preferred expression of linked polynucleotides. Also provided are methods for identifying gene function, and methods for repressing transmission of transgenes.

10. 发明专利

NZ263025A DEVELOPMENT GENES AND PROTEINS FROM PLANTS HOMOLOGOUS TO MAMMALIAN QM GENES AND THEIR USE 未知
公开(公告)号：NZ263025A
公开(公告)日：1997-08-22
申请号：NZ26302594
申请日：1994-03-09
申请人： PIONEER HI BRED INT
发明人： NEILL JOHN D , PIERCE DOROTHY A , CIGAN ANDREW M
IPC分类号： C07K14/415 , C12N15/09 , C12N15/29 , C12N15/82 , C12P21/02 , A01H1/00 , C12R1/91 , A01H5/00
摘要： A family of genes has been found in plants, said genes encoding a family of developmental proteins that have homologous structures to the mammalian QM genes. Recombinant molecules which include the QM genes in plants are useful to transform cells and regenerate plants that, as a result, have altered developmental pathways. Methods of producing male sterile plants use recombinant molecules containing either the QM sense genes or antesense genes with appropriate promoters.

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