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1. 发明公开

EP1633234A4 SYSTEMS AND METHODS FOR DETERMINING INTRACRANIAL PRESSURE NON-INVASIVELY AND ACOUSTIC TRANSDUCER ASSEMBLIES FOR USE IN SUCH SYSTEMS 审中-公开
标题翻译：系统和方法颅骨内的压力和传感器安排无创确定FOR USE在这些系统
公开(公告)号：EP1633234A4
公开(公告)日：2009-05-13
申请号：EP04754563
申请日：2004-06-03
申请人： PHYSIOSONICS INC , UNIV WASHINGTON , MOURAD PIERRE , MOHR BRANDT , KLIOT MICHEL , FREDERICKSON ROBERT C A , THOMPSON LEE R , SEAWALL JASON
发明人： MOURAD PIERRE , MOHR BRANDT , KLIOT MICHEL , FREDERICKSON ROBERT C A , THOMPSON LEE R , SEAWALL JASON
IPC分类号： A61B8/00 , A61B5/03 , A61B8/02 , A61B8/06 , A61B8/12 , A61B8/14
CPC分类号： A61B8/06 , A61B5/031 , A61B5/4064 , A61B5/7267 , A61B8/0808 , A61B8/4444 , A61B8/4472 , A61B8/4483 , A61B8/485 , A61B8/58
摘要： Systems and methods for determining ICP based on parameters that can be measured using non-invasive or minimally invasive techniques are provided, wherein a non-linear relationship is used to determine ICP based on one or more variable inputs. The first variable input relates to one or more properties of a cranial blood vessel and/or blood flow, such as acoustic backscatter from an acoustic transducer having a focus trained on a cranial blood vessel, flow velocity in a cranial blood vessel, and the like. Additional variables, such as arterial blood pressure (ABP), may be used in combination with a first variable input relating to one or more properties of a cranial blood vessel, such as flow velocity of the middle cerebral artery (MCA) to derive ICP using a non-linear relationship. Methods and systems for locating target areas based on their acoustic properties and for acoustic scanning of an area, identification of a target area of interest based on acoustic properties, and automated focusing of an acoustic source and/or detector on a desired target area are also provided. Acoustic transducer assemblies are described.

2. 发明申请

WO2004107963A3 NON-INVASIVE DETERMINATION OF INTRACRANIAL PRESSURE VIA ACOUSTIC TRANSDUCERS 审中-公开
标题翻译：通过声学传感器非侵入式确定压力
公开(公告)号：WO2004107963A3
公开(公告)日：2007-05-31
申请号：PCT/US2004017992
申请日：2004-06-03
申请人： ALLEZ PHYSIONIX LTD , UNIV WASHINGTON , MOURAD PIERRE , MOHR BRANDT , KLIOT MICHEL , FREDERICKSON ROBERT C A , THOMPSON LEE R , SEAWALL JASON
发明人： MOURAD PIERRE , MOHR BRANDT , KLIOT MICHEL , FREDERICKSON ROBERT C A , THOMPSON LEE R , SEAWALL JASON
IPC分类号： A61B8/00 , A61B5/03 , A61B8/02 , A61B8/06 , A61B8/12 , A61B8/14
CPC分类号： A61B8/06 , A61B5/031 , A61B5/4064 , A61B5/7267 , A61B8/0808 , A61B8/4444 , A61B8/4472 , A61B8/4483 , A61B8/485 , A61B8/58
摘要： Systems and methods for determining ICP based on parameters that can be measured using non-invasive or minimally invasive techniques are provided, wherein a non-linear relationship is used to determine ICP based on one or more variable inputs. The first variable input relates to one or more properties of a cranial blood vessel and/or blood flow, such as acoustic backscatter from an acoustic transducer having a focus trained on a cranial blood vessel, flow velocity in a cranial blood vessel, and the like. Additional variables, such as arterial blood pressure (ABP), may be used in combination with a first variable input relating to one or more properties of a cranial blood vessel, such as flow velocity of the middle cerebral artery (MCA) to derive ICP using a non-linear relationship. Methods and systems for locating target areas based on their acoustic properties and for acoustic scanning of an area, identification of a target area of interest based on acoustic properties, and automated focusing of an acoustic source and/or detector on a desired target area are also provided. Acoustic transducer assemblies are described.
摘要翻译：提供了基于可以使用非侵入性或微创技术测量的参数来确定ICP的系统和方法，其中使用非线性关系来基于一个或多个可变输入来确定ICP。第一可变输入涉及颅血管和/或血流的一种或多种性质，例如来自具有在颅血管上训练的焦点的声学换能器的声学后向散射，颅血管中的流速等。附加变量，例如动脉血压（ABP）可以与与颅血管的一种或多种性质（例如大脑中动脉（MCA）的流速）相关的第一可变输入组合使用，以便使用非线性关系。基于它们的声学特性和对于区域的声学扫描来定位目标区域的方法和系统也基于声学特性识别目标区域，以及声源和/或检测器在期望的目标区域上的自动聚焦也是提供。描述了声学换能器组件。

3. 发明专利

AU2004258175A1 Systems and methods implementing frequency-steered acoutic arrays for 2D and 3D imaging 未知
公开(公告)号：AU2004258175A1
公开(公告)日：2005-01-27
申请号：AU2004258175
申请日：2004-07-12
申请人： BLUE VIEW TECHNOLOGIES INC , BACHELOR SCOTT , THOMPSON R , SEAWALL JASON
发明人： THOMPSON R , SEAWALL JASON , BACHELOR SCOTT
IPC分类号： G01S15/89 , G10K11/34
摘要： Acoustic arrays transmitting and/or receiving multiple, angularly dispersed acoustic beams are used to generate 2D and 3D images. The acoustic arrays may comprise frequency-steered acoustic arrays provided in one-dimensional linear and two dimensional planar and curvilinear configurations, which may be operated as single order or multiple order arrays, may employ periodic or non-periodic transducer element spacing, and may be mechanically scanned to generate 2D and 3D volumetric data. Methods and systems for operating acoustic arrays in a frequency-steered mode in combination a mechanical beam steering mode, electronic time-delay and phase shift beam forming modes, and phase comparison angle estimation modes are also provided. Methods for generating two and three dimensional images of underwater target scenes using multi-beam acoustic imaging systems are disclosed.

4. 发明公开

EP1656568A4 SYSTEMS AND METHODS IMPLEMENTING FREQUENCY-STEERED ACOUTIC ARRAYS FOR 2D AND 3D IMAGING 有权转让
标题翻译：履行频率的系统和方法控制了2D和3D图形Acoutic阵列
公开(公告)号：EP1656568A4
公开(公告)日：2011-04-13
申请号：EP04778076
申请日：2004-07-12
申请人： BLUE VIEW TECHNOLOGIES INC , BACHELOR SCOTT , THOMPSON R , SEAWALL JASON
发明人： BACHELOR SCOTT , THOMPSON R , SEAWALL JASON
IPC分类号： G01S15/89 , G10K11/32 , G10K11/34
CPC分类号： G10K11/343 , G01S7/6245 , G01S15/89 , G01S15/8952 , G01S15/8993 , G10K11/34
摘要： Frequency-steered acoustic arrays transmitting and/or receiving multiple, angularly dispersed acoustic beams are used to generate 2D and 3D images. Input pulses to the arrays are generally non-linear, frequency-modulated pulses. Frequency-steered acoustic arrays may be provided in one-dimensional linear and two dimensional planar and curvilinear configurations, may be operated as single order or multiple order arrays, may employ periodic or non-periodic transducer element spacing, and may be mechanically scanned to generate 2D and 3D volumetric data. Multiple imaging fields of view may generated in different directions by switching the polarity of phase-shifted array transducer elements. Multiple frequency-steered arrays arranged in an X-configuration provide a wide, contiguous field of view and multiple frequency steered arrays arranged in a T-configuration provide orthogonally oriented fields of view. Methods and systems for operating acoustic arrays in a frequency-steered mode in combination a mechanical beam steering mode, electronic time-delay and phase shift beam forming modes, and phase comparison angle estimation modes are also provided.
摘要翻译：频率转向声学阵列发射和/或接收多个，角色散声束被用于产生2D和3D图像。输入脉冲到阵列是基因反弹非线性调频脉冲。频率转向声学阵列可以在一维线性的和二维的平面和曲线构型提供，可被操作为单阶或多阶的阵列，可以使用周期性的或非周期性的换能器元件的间隔，并且可以被机械地扫描，以生成二维和三维体数据。多个视摄像视场可以通过切换相移阵列换能器元件的极性在不同的方向上产生。在布置成X-配置的多个频率转向式阵列提供宽视的，连续的场和多个频率转向以T构型提供视正交定向的字段排列阵列。了方法和系统用于在组合的机械波束操纵的方式以频率转向模式中操作的声学阵列，因此提供电子延时和相移波束成形模式，以及相角比较估计模式。

5. 发明申请

WO2005008272A3 SYSTEMS AND METHODS IMPLEMENTING FREQUENCY-STEERED ACOUTIC ARRAYS FOR 2D AND 3D IMAGING 审中-公开
标题翻译：系统和方法实施用于二维和三维成像的频率转向的声学阵列
公开(公告)号：WO2005008272A3
公开(公告)日：2007-01-04
申请号：PCT/US2004022377
申请日：2004-07-12
申请人： BLUE VIEW TECHNOLOGIES INC , BACHELOR SCOTT , THOMPSON R , SEAWALL JASON
发明人： BACHELOR SCOTT , THOMPSON R , SEAWALL JASON
IPC分类号： G01S15/89 , G01S15/00 , G10K11/34
CPC分类号： G10K11/343 , G01S7/6245 , G01S15/89 , G01S15/8952 , G01S15/8993 , G10K11/34
摘要： Frequency-steered acoustic arrays [30, 60, 120, etc.] transmitting and/or receiving multiple, angularly dispersed acoustic beams are used to generate 2D and 3D images. Input pulses to the arrays are generally non-linear, frequency-modulated pulses. Frequency-steered acoustic arrays may be provided in one-dimensional linear and two dimensional planar and curvilinear configurations, may be operated as single order or multiple order arrays, may employ periodic or non-periodic transducer element spacing, and may be mechanically scanned to generate 3D volumetric data. Multiple imaging fields of view may generated in different directions by switching the polarity of phase-shifted array transducer elements. Multiple frequency-steered arrays arranged in an X-configuration [150, 152, 164, 166] provide a wide, contiguous field of view and multiple frequency steered arrays arranged in a T-configuration [170, 172, 220] provide orthogonally oriented fields of view. Methods and systems for operating acoustic arrays in a frequency-steered mode in combination a mechanical beam steering mode, electronic time-delay and phase shift beam forming modes, and phase comparison angle estimation modes are also provided.
摘要翻译：使用发射和/或接收多个角度分散的声束的频率转向声阵（30,60,120等）来产生2D和3D图像。对阵列的输入脉冲通常是非线性的调频脉冲。频率转向声阵可以以一维线性和二维平面和曲线配置提供，可以作为单次或多次阵列来操作，可以采用周期性或非周期性的换能器元件间隔，并且可以机械地扫描以产生 3D体积数据。通过切换相移阵列换能器元件的极性，可以在不同方向上产生多个成像视场。以X配置（150,152,164,166）排列的多个频率转向阵列提供了宽广的连续视场，并且以T形配置的多个频率转向阵列[170,172,220]提供正交定向的场看法。还提供了组合机械波束操纵模式，电子时间延迟和相移波束形成模式以及相位比较角度估计模式的以频率转向模式操作声阵列的方法和系统。

6. 发明专利

CA2539414A1 SYSTEMS AND METHODS FOR DETERMINING INTRACRANIAL PRESSURE NON-INVASIVELY AND ACOUSTIC TRANSDUCER ASSEMBLIES FOR USE IN SUCH SYSTEMS 未知
公开(公告)号：CA2539414A1
公开(公告)日：2004-12-16
申请号：CA2539414
申请日：2004-06-03
申请人： ALLEZ PHYSIONIX LTD , UNIV WASHINGTON
发明人： MOHR BRANDT , KLIOT MICHEL , MOURAD PIERRE , FREDERICKSON ROBERT C A , THOMPSON R LEE , SEAWALL JASON
IPC分类号： A61B5/03 , A61B8/00 , A61B8/04 , A61B8/06

7. 发明专利

AT426345T 未知
公开(公告)号：AT426345T
公开(公告)日：2009-04-15
申请号：AT04810267
申请日：2004-11-03
申请人： UNIV WASHINGTON
发明人： MOURAD PIERRE , OLSON FRANCIS , THOMPSON ROGER , SEAWALL JASON
IPC分类号： A46B9/04 , A46B13/02 , A46B15/00 , A61C20060101 , A61C17/20 , A61C17/22 , A61C17/34
摘要： A power toothbrush (10) is disclosed having a handle (15), battery (12), ultrasonic drive circuit (14), motor (16), control unit (18), and toothbrush head (20). The toothbrush head includes bristles (26) and a waveguide (24) that is operatively connected to an ultrasonic transducer (22). The waveguide facilitates the transmission of acoustic energy into the dental fluid to achieve improved cleaning and stain removal and improved cleaning in interproximal and subgingival regions. In one embodiment an ultrasound transducer module (30) includes a plurality of piezoelectric elements (32, 34) that may be mechanically connected in series, and electrically connected in parallel. One or more contacts (36) connect the elements, and a waveguide structure (50). An impedance matching layer (38) may be provided between the waveguide and the ultrasonic transducer module. The waveguide may be formed from a relatively soft material, for example, a polymer having a hardness between 10 and 65 Shore A.

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