专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明申请

WO2016055585A1 MULTIPLE HOST RANGE BACTERIOPHAGE WITH HYBRID TAIL FIBRES 审中-公开
标题翻译：多重主机范围与混合尾纤纤维混合
公开(公告)号：WO2016055585A1
公开(公告)日：2016-04-14
申请号：PCT/EP2015/073294
申请日：2015-10-08
申请人： PHICO THERAPEUTICS LTD
发明人： FAIRHEAD, Heather , WILKINSON, Adam , PITTS, Katy , BARNARD, Anne , SEVERI, Emmanuele , ANDERSON, Neil
IPC分类号： C12N7/00
CPC分类号： C12N7/00 , A61K35/74 , A61K35/76 , C12N2795/00011 , C12N2795/00032 , C12N2795/00043 , C12N2795/00045
摘要： Modified bacteriophage, uses thereof, and compositions containing the modified bacteriophage are described. The compositions are useful for human treatment and may treat various conditions, including bacterial infections.
摘要翻译：描述了改良的噬菌体，其用途和含有改性噬菌体的组合物。所述组合物可用于人类治疗，并可治疗各种病症，包括细菌感染。

2. 发明申请

WO2016055585A9 MULTIPLE HOST RANGE BACTERIOPHAGE WITH HYBRID TAIL FIBRES 审中-公开
公开(公告)号：WO2016055585A9
公开(公告)日：2016-04-14
申请号：PCT/EP2015/073294
申请日：2015-10-08
申请人： PHICO THERAPEUTICS LTD
发明人： FAIRHEAD, Heather , WILKINSON, Adam , PITTS, Katy , BARNARD, Anne , SEVERI, Emmanuele , ANDERSON, Neil
IPC分类号： C12N7/00
摘要： Modified bacteriophage, uses thereof, and compositions containing the modified bacteriophage are described. The compositions are useful for human treatment and may treat various conditions, including bacterial infections.

3. 发明申请

WO2017009418A1 MODIFYING BACTERIOPHAGE 审中-公开
标题翻译：修饰细菌
公开(公告)号：WO2017009418A1
公开(公告)日：2017-01-19
申请号：PCT/EP2016/066750
申请日：2016-07-14
申请人： PHICO THERAPEUTICS LTD
发明人： WILKINSON, Adam , FAIRHEAD, Heather, Marie , SEVERI, Emmanuele , BARNARD, Anne, Mary, Louise , ANDERSON, Neil
IPC分类号： C12N7/00
CPC分类号： C12N7/00 , C12N2795/00021 , C12N2795/00052
摘要： The present invention relates to a method for modifying the genome of a lytic target phage, uses of the method and products thereof.
摘要翻译：本发明涉及一种修饰裂解靶噬菌体基因组的方法及其方法及其产物的用途。

4. 发明申请

WO2016055587A1 MODIFYING BACTERIOPHAGE USING BETA-GALACTOSIDASE AS A SELECTABLE MARKER 审中-公开
标题翻译：使用β-GALACTOSIDASE作为可选标记来修饰细菌
公开(公告)号：WO2016055587A1
公开(公告)日：2016-04-14
申请号：PCT/EP2015/073297
申请日：2015-10-08
申请人： PHICO THERAPEUTICS LTD
发明人： FAIRHEAD, Heather , WILKINSON, Adam , ANDERSON, Neil , PITTS, Katy , BARNARD, Anne , SEVERI, Emmanuele
IPC分类号： C12N7/00
CPC分类号： A61K35/76 , A61K35/00 , C12N7/00 , C12N2795/00032 , C12N2795/00041 , C12N2795/00043 , C12N2795/00045
摘要： A method for modifying the genome of a target phage is described. Compositions comprising such modified phage are also described. The compositions may be formulated as a medicament, which are useful for human treatment and may treat various conditions, including bacterial infections.
摘要翻译：描述了用于修饰目标噬菌体的基因组的方法。还描述了包含这种修饰的噬菌体的组合物。组合物可以配制成药物，其可用于人类治疗，并且可以治疗各种病症，包括细菌感染。

5. 发明申请

WO2016055586A9 MODIFYING BACTERIOPHAGE 审中-公开
公开(公告)号：WO2016055586A9
公开(公告)日：2016-04-14
申请号：PCT/EP2015/073296
申请日：2015-10-08
申请人： PHICO THERAPEUTICS LTD
发明人： FAIRHEAD, Heather , WILKINSON, Adam , BARNARD, Anne , SEVERI, Emmanuele , ANDERSON, Neil , PITTS, Katy
IPC分类号： C12N7/00 , A61K35/76
摘要： A method for modifying the genome of a lytic target phage, uses of the method and products thereof are described. Compositions comprising such phage are also described. The compositions may be formulated as a medicament, which are useful for human treatment and may treat various conditions, including bacterial infections.

6. 发明申请

WO2016055584A9 MULTIPLE HOST RANGE BACTERIOPHAGE WITH DIFFERENT TAIL FIBRES 审中-公开
公开(公告)号：WO2016055584A9
公开(公告)日：2016-04-14
申请号：PCT/EP2015/073293
申请日：2015-10-08
申请人： PHICO THERAPEUTICS LTD
发明人： FAIRHEAD, Heather , WILKINSON, Adam , SEVERI, Emmanuele , ANDERSON, Neil , PITTS, Katy , BARNARD, Anne
IPC分类号： C12N7/00
摘要： Modified bacteriophage, uses thereof, and compositions containing the modified bacteriophage are described. The compositions are useful for human treatment and may treat various conditions, including bacterial infections.

7. 发明申请

WO2017174809A1 MODIFYING BACTERIOPHAGE 审中-公开
标题翻译：修改细菌
公开(公告)号：WO2017174809A1
公开(公告)日：2017-10-12
申请号：PCT/EP2017/058468
申请日：2017-04-07
申请人： PHICO THERAPEUTICS LTD
发明人： FAIRHEAD, Heather , WILKINSON, Adam , SEVERI, Emmanuele
IPC分类号： C12N15/00 , A61K35/76 , C12N7/00 , C12N15/10 , C12N15/62
摘要： A method for producing one or more hybrid bacteriophage host range determinant (HRD) sequences, which comprises: (1) identifying at least two DNA sequences, each encoding an HRD in a series of regions in the DNA sequence, wherein the HRDs are different from one another, (2) incorporating each region into a vector in which each region is flanked by a recognition site of a restriction enzyme capable of cutting DNA at a specific cleavage site outside of the recognition sequence, so that the cleavage site of the restriction enzyme is situated at the boundary of each region, wherein the cleavage site sequences of the regions from an individual series are different from one another and wherein the cleavage site sequences at the boundaries of corresponding regions from different series are the same; (3) treating the vectors with a restriction enzyme capable of cutting DNA at a specific cleavage site outside of the recognition sequence so as to generate a mixture of the regions; and (4) treating the mixture of the regions with a ligase to ligate them to form an array of DNA sequences encoding an array of hybrid HRDs.
摘要翻译：一种用于产生一个或多个杂交噬菌体宿主范围决定簇（HRD）序列的方法，其包括：（1）鉴定至少两个DNA序列，每个DNA序列编码DNA中一系列区域中的HRD 序列，其中HRD彼此不同，（2）将每个区域整合入载体中，其中每个区域侧翼为能够在识别序列之外的特定切割位点切割DNA的限制性酶的识别位点，所以限制酶的切割位点位于每个区域的边界处，其中来自各个系列的区域的切割位点序列彼此不同，并且其中来自不同系列的相应区域的边界处的切割位点序列是一样; （3）用能够在识别序列之外的特定切割位点切割DNA的限制性内切酶处理载体，以产生这些区域的混合物; 和（4）用连接酶处理区域的混合物以连接它们以形成编码混合HRD阵列的DNA序列阵列。

8. 发明申请

WO2016055586A1 MODIFYING BACTERIOPHAGE 审中-公开
标题翻译：修饰细菌
公开(公告)号：WO2016055586A1
公开(公告)日：2016-04-14
申请号：PCT/EP2015/073296
申请日：2015-10-08
申请人： PHICO THERAPEUTICS LTD
发明人： FAIRHEAD, Heather , WILKINSON, Adam , BARNARD, Anne , SEVERI, Emmanuele , ANDERSON, Neil , PITTS, Katy
IPC分类号： C12N7/00 , A61K35/76
CPC分类号： A61K35/76 , A61K35/00 , C12N7/00 , C12N2795/00011 , C12N2795/10121 , C12N2795/10144
摘要： A method for modifying the genome of a lytic target phage, uses of the method and products thereof are described. Compositions comprising such phage are also described. The compositions may be formulated as a medicament, which are useful for human treatment and may treat various conditions, including bacterial infections.
摘要翻译：描述了用于修饰裂解靶噬菌体的基因组的方法，其方法及其产物的用途。还描述了包含这种噬菌体的组合物。组合物可以配制成药物，其可用于人类治疗，并且可以治疗各种病症，包括细菌感染。

9. 发明申请

WO2016055584A1 MULTIPLE HOST RANGE BACTERIOPHAGE WITH DIFFERENT TAIL FIBRES 审中-公开
标题翻译：多个主动范围细菌与不同的尾纤纤维
公开(公告)号：WO2016055584A1
公开(公告)日：2016-04-14
申请号：PCT/EP2015/073293
申请日：2015-10-08
申请人： PHICO THERAPEUTICS LTD
发明人： FAIRHEAD, Heather , WILKINSON, Adam , SEVERI, Emmanuele , ANDERSON, Neil , PITTS, Katy , BARNARD, Anne
IPC分类号： C12N7/00
CPC分类号： C12N7/00 , A61K35/74 , A61K35/76 , C12N2795/00011 , C12N2795/00032 , C12N2795/00043 , C12N2795/00045
摘要： Modified bacteriophage, uses thereof, and compositions containing the modified bacteriophage are described. The compositions are useful for human treatment and may treat various conditions, including bacterial infections.
摘要翻译：描述了改良的噬菌体，其用途和含有改性噬菌体的组合物。该组合物可用于人类治疗，并可治疗各种病症，包括细菌感染。

10. 发明公开

EP3440204A1 MODIFYING BACTERIOPHAGE 审中-公开
公开(公告)号：EP3440204A1
公开(公告)日：2019-02-13
申请号：EP17717131.1
申请日：2017-04-07
申请人： Phico Therapeutics Ltd
发明人： FAIRHEAD, Heather , WILKINSON, Adam , SEVERI, Emmanuele
IPC分类号： C12N15/00 , A61K35/76 , C12N7/00 , C12N15/10 , C12N15/62

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式