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1. 发明申请

WO03095475A8 PEPTIDE COMPOUNDS AND THEIR USE AS PROTEASE SUBSTRATES 审中-公开
标题翻译：肽类化合物及其作为蛋白质底物的用途
公开(公告)号：WO03095475A8
公开(公告)日：2004-06-10
申请号：PCT/US0314869
申请日：2003-05-10
申请人： PHARMACIA CORP , DECRESCENZO GARY A , HOWARD CAROL P , RICO JOSEPH G , ZHANG KUN
发明人： DECRESCENZO GARY A , HOWARD CAROL P , RICO JOSEPH G , ZHANG KUN
IPC分类号： C07K7/02 , C07K7/04 , C07K7/06 , C07K7/08 , C07K14/00 , C07K14/78 , C12Q1/37 , G01N33/53 , C12N9/52 , C12N1/00
CPC分类号： C07K7/06 , C07K7/08 , C07K14/78 , C12Q1/37 , C12Q2337/00 , G01N2333/96486 , G01N2500/02
摘要： This invention is directed generally to peptide compounds and salts, and particularly to peptide compounds and salts that are useful as protease substrates, such as matrix metalloprotease ("MMP") substrates. This invention also is directed to methods for making such compounds and salts, as well as amino acids that may, for example, be used in such methods. This invention is further directed to methods for using such compounds and salts to, for example, evaluate the effectiveness of potential protease inhibitors and to detect or monitor a disease associated with protease activity.
摘要翻译：本发明一般涉及肽化合物和盐，特别涉及可用作蛋白酶底物的肽化合物和盐，例如基质金属蛋白酶（“MMP”）底物。本发明还涉及制备此类化合物和盐的方法，以及可用于例如这些方法的氨基酸。本发明进一步涉及使用这些化合物和盐来评估潜在蛋白酶抑制剂的有效性并检测或监测与蛋白酶活性相关的疾病的方法。

2. 发明专利

ITMI20080137A1 COMPLESSO DI DISCHI DELLA FRIZIONE 未知
公开(公告)号：ITMI20080137A1
公开(公告)日：2008-08-01
申请号：ITMI20080137
申请日：2008-01-30
申请人： ZHANG KUN , ZHOU SHUMING
发明人： ZHANG KUN

3. 发明专利

ITMI20110266U1 COMPLESSO DI DISCHI DELLA FRIZIONE. 未知
公开(公告)号：ITMI20110266U1
公开(公告)日：2011-10-31
申请号：ITMI20110266
申请日：2011-08-01
申请人： ZHANG KUN , ZHOU SHUMING
发明人： ZHANG KUN
IPC分类号： F16D20060101

4. 发明申请

WO2013192455A3 STATUS AWARE MEDIA PLAY 审中-公开
标题翻译：状态特技媒体播放
公开(公告)号：WO2013192455A3
公开(公告)日：2014-02-20
申请号：PCT/US2013046908
申请日：2013-06-20
申请人： GOOGLE INC , ZHANG KUN , CHANG KEVIN DONGSOO
发明人： ZHANG KUN
IPC分类号： G06F15/16 , G06F15/173
CPC分类号： H04L43/08 , G06Q30/0255 , G06Q30/0631 , H04L65/4092 , H04L65/80 , H04L67/22 , H04L67/306
摘要： Techniques for determining status aware media play are described. When current user behavior with respect to a media segment deviates from baseline user behavior, the media segment is tagged in memory, and a determination is made as to whether playback functionality with respect to the tagged media segment should be adjusted.
摘要翻译：描述了用于确定状态感知媒体播放的技术。当相对于媒体片段的当前用户行为偏离基准用户行为时，媒体片段被标记在存储器中，并且确定是否应当调整关于标记的媒体片段的播放功能。

5. 发明申请

WO2011059554A3 TREATMENT PLANNING IN A VIRTUAL ENVIRONMENT 审中-公开
标题翻译：虚拟环境中的治疗计划
公开(公告)号：WO2011059554A3
公开(公告)日：2011-10-06
申请号：PCT/US2010048374
申请日：2010-09-10
申请人： ACCURAY INC , WANG BAI , ZHANG KUN , CHENG XIANGYONG , CHANG I-NING , HILL ROBERT W , SIMS COLIN , WANG HONGWU
发明人： WANG BAI , ZHANG KUN , CHENG XIANGYONG , CHANG I-NING , HILL ROBERT W , SIMS COLIN , WANG HONGWU
IPC分类号： G06F19/00
CPC分类号： G06F3/04815 , A61N5/103 , G06F19/3481 , G16H50/50
摘要： A method and apparatus for treatment planning are described. A treatment planning system provides a computer- simulated virtual environment including a virtual artifact that is a three-dimensional simulation of a patient anatomy, wherein the three-dimensional simulation is generated from one or more diagnostic images taken of the patient anatomy. The treatment planning system performs a treatment planning operation associated with the virtual artifact in response to a user interaction with the virtual environment.
摘要翻译：描述了治疗计划的方法和装置。治疗计划系统提供计算机模拟的虚拟环境，其包括作为患者解剖结构的三维模拟的虚拟假象，其中所述三维模拟是从取自患者解剖结构的一个或多个诊断图像生成的。治疗计划系统响应于与虚拟环境的用户交互，执行与虚拟伪影相关联的治疗计划操作。

6. 发明申请

WO2010151891A2 PREDETERMINED DUTY CYCLE SIGNAL GENERATOR 审中-公开
标题翻译：预测的占空比信号发生器
公开(公告)号：WO2010151891A2
公开(公告)日：2010-12-29
申请号：PCT/US2010040249
申请日：2010-06-28
申请人： QUALCOMM INC , ZHANG KUN , BARNETT KENNETH CHARLES
发明人： ZHANG KUN , BARNETT KENNETH CHARLES
IPC分类号： H03K3/017
CPC分类号： H03K5/1565 , H03K21/38 , H03K23/00
摘要： Techniques for generating a signal having a predetermined duty cycle. In an exemplary embodiment, a first counter is configured to count a first number of cycles of an oscillator signal, and a second counter is configured to count a second number of cycles of the oscillator signal, with the second number being greater than the first number. The output of the second counter is used to reset the first and second counters, while the outputs of the first and second counters further drive a toggle latch for generating the signal having predetermined duty cycle. Further aspects include techniques for accommodating odd and even values for the second number.
摘要翻译：用于产生具有预定占空比的信号的技术。在示例性实施例中，第一计数器被配置为对振荡器信号的第一数量的周期进行计数，并且第二计数器被配置为对振荡器信号的第二数量的周期进行计数，其中第二数量大于第一数量。第二计数器的输出用于复位第一和第二计数器，而第一和第二计数器的输出进一步驱动用于产生具有预定占空比的信号的触发锁存器。另外的方面包括用于适应第二数量的奇数和偶数值的技术。

7. 发明申请

WO2007117554A3 INSTANT-ON HEATER 审中-公开
标题翻译：即时加热器
公开(公告)号：WO2007117554A3
公开(公告)日：2008-08-28
申请号：PCT/US2007008513
申请日：2007-04-05
申请人： KOPIN CORP , ZHANG KUN , HERRMANN FREDERICK P
发明人： ZHANG KUN , HERRMANN FREDERICK P
IPC分类号： G06F3/038 , G02F1/1333
CPC分类号： G02F1/133382 , G02F1/1362 , G02F1/136213 , G02F2202/104 , G09G3/3648 , G09G3/3655 , G09G2300/0426 , G09G2320/041
摘要： A heater, used in a Liquid Crystal Display (LCD) pixel array that uses a common voltage polysilicon line to supply heat to the pixel elements, instead of using active control transistor input lines, such as gate input lines. The approach permits the display to be activated during the warm-up process.
摘要翻译：用于液晶显示器（LCD）像素阵列中的加热器，其使用公共电压多晶硅线路来向像素元件供热，而不是使用诸如栅极输入线的有源控制晶体管输入线。该方法允许在预热过程中激活显示。

8. 发明申请

WO2009083193A3 METHOD AND APPARATUS FOR SURFACE TREATMENT BY COMBINED PARTICLE IRRADIATION 审中-公开
标题翻译：通过组合颗粒辐照处理表面处理的方法和装置
公开(公告)号：WO2009083193A3
公开(公告)日：2010-06-10
申请号：PCT/EP2008010939
申请日：2008-12-19
申请人： UNIV GOETTINGEN GEORG AUGUST , HOFSAESS HANS , ZHANG KUN
发明人： HOFSAESS HANS , ZHANG KUN
IPC分类号： C23C14/02
CPC分类号： C23C14/46 , C23C14/022
摘要： The invention relates to a method for surface treatment of a substrate surface by irradiation of particles onto the substrate constituting the substrate surface. The method comprises the steps of applying first particles onto the substrate surface, thereby causing a positive particle flux component on the substrate surface and emitting eroding particles as at least an eroding particle beam onto the substrate surface, the eroding particle beam causing a negative particle flux component on the substrate surface. The application is performed concurrently or alternately with the step of emitting. An area of the substrate surface onto which the first particles are applied is at least partly overlapping an area of the substrate surface irradiated by the eroding particle beam in an overlapping area of the substrate surface. The resulting cumulative flux of the combined positive and negative flux components in the overlapping area being non-positive, the resulting cumulative flux providing a decreasing or stable net amount of particles in the overlapping area of the substrate surface. The first particles and the eroding particle beam comprising atomic or molecular particles, wherein the first particles are provided by a source outside a plane coextending with at least a part of the substrate surface. Further, the invention relates to a device for surface treatment and a target device for carrying out the inventive surface treatment method.
摘要翻译：本发明涉及通过将粒子照射在构成基板表面的基板上来对基板表面进行表面处理的方法。该方法包括以下步骤：将第一粒子施加到衬底表面上，从而在衬底表面上引起正的粒子通量分量，并将侵蚀粒子作为至少一个侵蚀粒子束发射到衬底表面上，侵蚀粒子束产生负的粒子通量部件在基板表面上。应用程序与发射步骤同时或交替执行。其上施加有第一颗粒的基板表面的区域至少部分地与基板表面的重叠区域中被侵蚀粒子束照射的基板表面的面积重叠。所得到的重叠区域中积极的和负的通量组分的累积通量是非正的，所得到的累积通量在衬底表面的重叠区域中提供了减少或稳定的净量的颗粒。第一颗粒和包含原子或分子颗粒的侵蚀粒子束，其中第一颗粒由与源于衬底表面的至少一部分共同延伸的平面外的源提供。此外，本发明涉及一种用于表面处理的装置和用于实施本发明的表面处理方法的目标装置。

9. 发明申请

WO2007092538A3 METHODS FOR MAKING NUCLEOTIDE PROBES FOR SEQUENCING AND SYNTHESIS 审中-公开
标题翻译：制备用于测序和合成的核酸探针的方法
公开(公告)号：WO2007092538A3
公开(公告)日：2008-12-11
申请号：PCT/US2007003334
申请日：2007-02-07
申请人： HARVARD COLLEGE , CHURCH GEORGE M , ZHANG KUN , CHOU JOSEPH
发明人： CHURCH GEORGE M , ZHANG KUN , CHOU JOSEPH
IPC分类号： C12P19/34 , C12Q1/68
CPC分类号： C12Q1/6813 , C12Q1/6837 , C12Q2535/113 , C12Q2537/143 , C12Q2565/543
摘要： Compositions and methods for making a plurality of probes for analyzing a plurality of nucleic acid samples are provided. Compositions and methods for analyzing a plurality of nucleic acid samples to obtain sequence information in each nucleic acid sample are also provided.
摘要翻译：提供了制备用于分析多个核酸样品的多个探针的组合物和方法。还提供了用于分析多个核酸样品以获得每个核酸样品中的序列信息的组合物和方法。

10. 发明申请

WO2008063477A3 SHIFTER REGISTER FOR LOW POWER CONSUMPTION APPLICATION 审中-公开
标题翻译：用于低功耗应用的SHIFTER寄存器
公开(公告)号：WO2008063477A3
公开(公告)日：2008-07-10
申请号：PCT/US2007023782
申请日：2007-11-14
申请人： KOPIN CORP , HERRMANN FREDERICK , ZHANG KUN
发明人： HERRMANN FREDERICK , ZHANG KUN
IPC分类号： G09G3/36
CPC分类号： G11C19/00 , G11C19/28
摘要： A high voltage shift register stage which directly accepts low voltage clock signal inputs without using clock buffers. In particular, a shift register stage circuit is adapted to operate with a low voltage swing clock signal, with the stage circuit having a single state node, a, driven directly. This arrangement allows for reduced power consumption and higher operating speeds.
摘要翻译：高电压移位寄存器级，不使用时钟缓冲器，直接接受低电压时钟信号输入。特别地，移位寄存器级电路适于以低电压摆动时钟信号来操作，其中级电路具有直接驱动的单个状态节点a。这种布置允许降低功耗和更高的运行速度。

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