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    • 2. 发明申请
    • METHOD AND SYSTEM TO PREDICT RESPONSE TO PAIN TREATMENTS
    • 预防疼痛治疗反应的方法和系统
    • WO2014151081A1
    • 2014-09-25
    • PCT/US2014/024939
    • 2014-03-12
    • PATHWAY GENOMICS CORPORATION
    • TREDICI, Andria, DelCHAN, Russell, Kuo-fuZHU, GuangdanBECKER, K., David
    • G06F19/10
    • C12Q1/6883C12Q2600/106C12Q2600/156C12Q2600/16
    • The present invention relates to systems and methods for predicting an individual's likely response to a pain medication comprising genotyping genetic variations in an individual to determine the individual's propensity for metabolizing a pain medication and likely response to a medication, and preferably diverse reactions to a medication. In particular, the invention comprises analyzing a biological sample provided by an individual, typically a patient or an individual diagnosed with a particular disorder, determining the individual's likely response to a particular treatment, more specifically a pain medication, and thereafter displaying, or further, recommending a plan of action or inaction. In particular, the present invention provides a grading method and system to profile an individual's response to one or more pain medication.
    • 本发明涉及用于预测个体对疼痛药物的可能反应的系统和方法,其包括对个体的遗传变异进行基因分型以确定个体代谢疼痛药物的倾向并且可能对药物的反应,并且优选对药物的多种反应。 特别地,本发明包括分析由个体(通常是患者或诊断为特定病症的个体)提供的生物样品,确定个体对特定治疗的可能反应,更具体地说是疼痛药物,然后显示或进一步显示, 推荐行动计划或不作为。 特别地,本发明提供了一种分级方法和系统,以分析个体对一种或多种止痛药物的反应。