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1. 发明授权

US5100384A Method and device for percutaneous intubation 失效
标题翻译：用于经皮插管的方法和装置
公开(公告)号：US5100384A
公开(公告)日：1992-03-31
申请号：US503454
申请日：1990-03-30
申请人： P. Bruce McBrien , John A. Karpiel
发明人： P. Bruce McBrien , John A. Karpiel
IPC分类号： A61F2/958 , A61J15/00
CPC分类号： A61J15/0023 , A61J15/0019 , A61J15/0042 , A61M25/10 , A61J15/0073
摘要： A catheter for intubating a stoma formed by a percutaneous endoscopic technique includes a multi-lumen tube and an inflatable cuff for retaining the catheter in place. The tube includes a fluid lumen for conveying fluid into a patient and an inflation lumen having a port in communication with the interior of the cuff to allow for the egress and ingress of fluid to the cuff. The cuff has contained therein a resilient sponge-like material which has the property that it will remain in its compressed state for an ascertainable period of time after having been maintained in the compressed state for a predetermined period of time, e.g., at least 24 hours. A period of time, not less than the predetermined period of time, prior to the intubation procedure, the cuff is compressed to expel air from the cuff through the inflation lumen and to compress the sponge-like material inside the cuff. A tubular sleeve is applied to the outside of the cuff to maintain the cuff and sponge-like material in its collapsed state. Prior to the intubation procedure, the sleeve is removed. Upon completion of intubation, when the cuff is positioned in a cavity, such as the stomach, internal to the patient, the sponge-like material is expanded by injecting a liquid such as distilled water into the cuff via the inflation lumen. The inflation lumen is then closed.
摘要翻译：用于插管通过经皮内窥镜技术形成的造口的导管包括多腔管和用于将导管保持在适当位置的可充气袖带。该管包括用于将流体输送到患者体内的流体腔和具有与袖带内部连通的端口的充气腔，以允许流体流出袖带。该袖带包含弹性海绵状材料，该材料具有在保持在压缩状态一段预定的时间（例如至少24小时）之后将保持处于其压缩状态一段可确定的时间段。在插管程序之前的一段时间内，不小于预定时间段，压缩袖带以从袖带排出通过充气腔的空气并压缩袖带内的海绵状材料。将管状套筒施加到袖带的外侧以将袖带和海绵状材料保持在其折叠状态。在插管过程之前，将套筒取出。在插管完成时，当袖带定位在患者内部的诸如胃的空腔中时，通过经由充气内腔将诸如蒸馏水的液体注射到袖带中来膨胀海绵状材料。然后关闭充气管腔。

2. 发明申请

US20110105950A1 Biopsy Collection Device 有权
标题翻译：活检收集装置
公开(公告)号：US20110105950A1
公开(公告)日：2011-05-05
申请号：US13004123
申请日：2011-01-11
申请人： John A. Karpiel
发明人： John A. Karpiel
IPC分类号： A61B10/02
CPC分类号： A61B10/06 , A61B1/00089 , A61B1/018 , A61B1/2736 , A61B10/0096 , A61B17/3462 , A61B2010/0225 , A61B2010/045 , A61B2017/00296 , A61B2017/3441
摘要： A method and device for removing tissue from a patient during a biopsy procedure utilizing a biopsy collection device are provided. The biopsy collection device includes a body portion configured for attachment to an endoscope and a receptacle portion configured to retain a portion of tissue removed from a target site during the biopsy procedure. The biopsy collection device further includes a passageway configured to receive a biopsy sampling device, such as a pair of forceps, passing through the endoscope to the target site.
摘要翻译：提供了一种在使用活组织检查收集装置的活组织检查过程中从患者去除组织的方法和装置。活组织检查收集装置包括构造成附接到内窥镜的主体部分和被配置为在活检过程期间保留从目标部位移除的一部分组织的容置部分。活组织检查收集装置还包括经配置以接收通过内窥镜到目标部位的活检取样装置，例如一对镊子。

3. 发明授权

US07878983B2 Biopsy collection device 有权
标题翻译：活检收集装置
公开(公告)号：US07878983B2
公开(公告)日：2011-02-01
申请号：US11877135
申请日：2007-10-23
申请人： John A. Karpiel
发明人： John A. Karpiel
IPC分类号： A61B10/00 , A61B1/00
CPC分类号： A61B10/06 , A61B1/00089 , A61B1/018 , A61B1/2736 , A61B10/0096 , A61B17/3462 , A61B2010/0225 , A61B2010/045 , A61B2017/00296 , A61B2017/3441
摘要： A method and device for removing tissue from a patient during a biopsy procedure utilizing a biopsy collection device are provided. The biopsy collection device includes a body portion configured for attachment to an endoscope and a receptacle portion configured to retain a portion of tissue removed from a target site during the biopsy procedure. The biopsy collection device further includes a passageway configured to receive a biopsy sampling device, such as a pair of forceps, passing through the endoscope to the target site.
摘要翻译：提供了一种在使用活组织检查收集装置的活组织检查过程中从患者去除组织的方法和装置。活组织检查收集装置包括构造成附接到内窥镜的主体部分和被配置为在活检过程期间保留从目标部位移除的一部分组织的容置部分。活组织检查收集装置还包括经配置以接收通过内窥镜到目标部位的活检取样装置，例如一对镊子。

4. 发明申请

US20070260266A1 LITHOTRIPSY COMPATIBLE WIRE BASKET 审中-公开
标题翻译： LITHOTRIPSY兼容线篮
公开(公告)号：US20070260266A1
公开(公告)日：2007-11-08
申请号：US11743732
申请日：2007-05-03
申请人： John A. Karpiel
发明人： John A. Karpiel
IPC分类号： A61B17/22
CPC分类号： A61B17/221 , A61B2017/2212
摘要： A medical device for performing lithotripsy on a foreign body within a patient. The medical device generally includes a wire basket constructed from distal portions of a plurality of multifilament wires. The distal portions of the plurality of multifilament wires each follow a generally helical path to give the wire basket a helical configuration. A method of performing lithotripsy is also provided using the medical device.
摘要翻译：用于在患者体内对异物进行碎石术的医疗装置。医疗装置通常包括由多根复丝线的远端部分构成的线篮。多个复丝线的远端部分各自沿着大致螺旋状的路径，以使丝网篮呈螺旋状。还使用医疗装置提供执行碎石术的方法。

5. 发明授权

US08206320B2 System and method for introducing multiple medical devices 有权
标题翻译：引入多种医疗器械的系统和方法
公开(公告)号：US08206320B2
公开(公告)日：2012-06-26
申请号：US10902625
申请日：2004-07-29
申请人： Stephen E. Deal , Matthew P. Carter , Victor D. Clark, Jr. , Frederick B. Haller , David M. Hardin, Jr. , John A. Karpiel , Kenneth C. Kennedy, II , Brian K. Rucker , Gregory J. Skerven , David F. Waller
发明人： Stephen E. Deal , Matthew P. Carter , Victor D. Clark, Jr. , Frederick B. Haller , David M. Hardin, Jr. , John A. Karpiel , Kenneth C. Kennedy, II , Brian K. Rucker , Gregory J. Skerven , David F. Waller
IPC分类号： A61B6/00
CPC分类号： A61B1/018 , A61B6/12 , A61B17/221 , A61B2017/2212 , A61F2/95 , A61F2002/041 , A61F2002/9511 , A61M25/0029 , A61M25/0662 , A61M25/10 , A61M2025/0183 , A61M2025/0681
摘要： A method and apparatus for introducing a first elongate medical device and short wire guide that are coupled together into a work site and remotely disconnecting them within the work site such that a secondary device comprising a catheter member can be introduced over the wire guide to the work site, and/or a second wire guide can be introduced to the work site via a passageway of the primary access device. A system of indicia, such as radiopaque or viewable markers, permit the operator to monitor the relative alignment of the devices within the work site to determine when uncoupling has occurred. In one example of the method, a wire guide and primary access device (e.g., a sphincterotome) is coupled to the wire guide and introduced via a duodenoscope into the biliary system. After performing a first medical operation, the devices are uncoupled with the wire guide being left within the biliary system such that a secondary access device, such as a balloon, biopsy device, stent delivery catheter, dilator, etc., can be introduced to perform a second medical operation without a traditional over-the-wire exchange being required. In another example of the method, a prosthesis, such as a valve or stent, is placed within the work site coupled to a wire guide which is remotely disconnected within the work site and a secondary device, such as a dilation balloon or second prosthesis, is introduced into the work site after the first delivery system is removed.
摘要翻译：一种用于引入第一细长医疗装置和短线引导件的方法和装置，所述第一细长医疗装置和短导线引导件联接在一起成为工作现场并在工作现场内远程地断开它们，使得包括导管部件的辅助装置可以被引导到导线器上，现场和/或第二导线引导件可以经由主接入设备的通道引入到工作现场。诸如不透射线或可见标记的标记系统允许操作者监视工作现场内的设备的相对对准以确定何时发生解偶联。在该方法的一个示例中，线导向器和主入口装置（例如括约肌切开机）联接到线导引件并经十二指肠镜引入胆道系统。在执行第一次医疗操作之后，将装置与线引导件脱离在胆汁系统内，使得可以引入二次进入装置，例如气囊，活检装置，支架输送导管，扩张器等，以执行不需要传统的线上交换即可进行第二次医疗。在该方法的另一示例中，诸如阀或支架的假体被放置在工作部位内，该工作部位与工作部位远程断开的线引导件相连，并且辅助装置（例如扩张气囊或第二假体）在第一个传送系统被删除之后被引入工作现场。

6. 发明申请

US20090043259A1 Sphincterotome 有权
标题翻译：脊柱括约肌
公开(公告)号：US20090043259A1
公开(公告)日：2009-02-12
申请号：US11835837
申请日：2007-08-08
申请人： David M. Hardin, JR. , John A. Karpiel
发明人： David M. Hardin, JR. , John A. Karpiel
IPC分类号： A61M5/178 , A61B17/22 , A61B17/32 , A61B18/18
CPC分类号： A61B18/1492 , A61B17/32056 , A61B2017/003 , A61B2017/22039 , A61B2018/00553 , A61B2018/1407 , A61B2018/144
摘要： A medical sphincterotome and a method of its use are described. The sphincterotome has structural elements that are capable of directing a wire guide through a selected body passageway. One structural element includes a distal port and deflection member that can deflect the wire guide into the desired passageway. Another structural element includes an offset nose-shaped end that can bend towards a passageway desired to be blocked. The wire guide is prevented from entering the blocked passageway, thereby enabling the wire guide to cannulate the desired passageway. The sphincterotome also includes a cutting wire to access a patient's sphincter and perform various other medical procedures.
摘要翻译：描述了一种医疗性括约肌切开术及其使用方法。括约肌切开术具有能够引导导线通过所选择的身体通道的结构元件。一个结构元件包括远端口和偏转构件，该远端口和偏转构件可将导线引导件偏转到所需的通道中。另一种结构元件包括偏移的鼻形端，其可朝向期望被阻挡的通道弯曲。导线导线被阻止进入阻塞的通道，从而使导线器能够插入所需的通道。括约肌切开术还包括切割线以访问患者的括约肌并执行各种其他医疗程序。

7. 发明授权

US06602250B2 Echogenic wire knife 有权
标题翻译：生锈丝刀
公开(公告)号：US06602250B2
公开(公告)日：2003-08-05
申请号：US09774442
申请日：2001-01-31
申请人： John A. Karpiel , Donagh O'Sullivan
发明人： John A. Karpiel , Donagh O'Sullivan
IPC分类号： A61B1814
CPC分类号： A61B18/1492 , A61B2018/144
摘要： A medical device for heat treatment of patient tissue includes an electrically conductive wire guide. The wire guide has a distal end and a proximal portion. A connector is disposed on the proximal portion of the wire guide for providing electrical power to the wire guide, thereby enabling the distal end of the wire guide to heat the patient tissue.
摘要翻译：用于患者组织的热处理的医疗装置包括导电线引导件。导线器具有远端和近端部分。连接器设置在线引导件的近端部分上，用于向线引导件提供电力，从而使线引导件的远端能够加热患者组织。

8. 发明授权

US08764768B2 Stapling device for closing perforations 有权
标题翻译：用于封闭穿孔的装订装置
公开(公告)号：US08764768B2
公开(公告)日：2014-07-01
申请号：US12548868
申请日：2009-08-27
申请人： John A. Karpiel
发明人： John A. Karpiel
IPC分类号： A61B17/10 , A61B17/08
CPC分类号： A61B17/0057 , A61B17/0643 , A61B17/068 , A61B17/08 , A61B17/10 , A61B17/12013 , A61B2017/00668
摘要： Medical devices and systems for easily and reliably closing a perforation in tissue. One embodiment of a medical device for use with a scope includes a tubular member having a distal end, an exterior surface and an interior space. A carrier element extends along the exterior surface and around the distal end of the tubular member. An elastic band is positioned on the carrier element around the exterior surface of the tubular member. A staple is positioned within the interior space of a tubular member and includes first and second prongs which are spaced apart and translatable relative to one another. The carrier element is structured to deliver the elastic band beyond the distal end of the tubular member where upon the elastic band contracts and engages the staple to translate the first and second prongs towards each other.
摘要翻译：用于容易且可靠地封闭组织穿孔的医疗装置和系统。用于范围的医疗装置的一个实施例包括具有远端，外表面和内部空间的管状构件。载体元件沿着外表面并且围绕管状构件的远端延伸。弹性带围绕管状构件的外表面定位在载体元件上。钉子定位在管状构件的内部空间内，并且包括相对于彼此间隔开并且可平移的第一和第二叉。载体元件被构造成将弹性带递送超过管状构件的远端，其中弹性带收缩并接合订书钉以将第一和第二插脚朝向彼此平移。

9. 发明授权

US08277392B2 Biopsy collection device 有权
标题翻译：活检收集装置
公开(公告)号：US08277392B2
公开(公告)日：2012-10-02
申请号：US13004123
申请日：2011-01-11
申请人： John A. Karpiel
发明人： John A. Karpiel
IPC分类号： A61B10/00 , A61B1/00
CPC分类号： A61B10/06 , A61B1/00089 , A61B1/018 , A61B1/2736 , A61B10/0096 , A61B17/3462 , A61B2010/0225 , A61B2010/045 , A61B2017/00296 , A61B2017/3441
摘要： A method and device for removing tissue from a patient during a biopsy procedure utilizing a biopsy collection device are provided. The biopsy collection device includes a body portion configured for attachment to an endoscope and a receptacle portion configured to retain a portion of tissue removed from a target site during the biopsy procedure. The biopsy collection device further includes a passageway configured to receive a biopsy sampling device, such as a pair of forceps, passing through the endoscope to the target site.
摘要翻译：提供了一种在使用活组织检查收集装置的活组织检查过程中从患者去除组织的方法和装置。活组织检查收集装置包括构造成附接到内窥镜的主体部分和被配置为在活检过程期间保留从目标部位移除的一部分组织的容置部分。活组织检查收集装置还包括经配置以接收通过内窥镜到目标部位的活检取样装置，例如一对镊子。

10. 发明授权

US08025691B2 Single peel stent introducer apparatus 有权
标题翻译：单皮支架引导器设备
公开(公告)号：US08025691B2
公开(公告)日：2011-09-27
申请号：US11454607
申请日：2006-06-16
申请人： Mathew P. Carter , Victor D. Clark , John A. Karpiel , Gregory J. Skerven
发明人： Mathew P. Carter , Victor D. Clark , John A. Karpiel , Gregory J. Skerven
IPC分类号： A61F2/06
CPC分类号： A61F2/95 , A61F2/966 , A61F2002/9517
摘要： A stent introducer apparatus includes a handle having a housing and a rotatable reel. An inner stent carrier having a proximal end and a distal end is provided, with the proximal end being connected to the housing of the handle. An outer sheath movably disposed about the inner stent carrier and having a proximal end and a distal end is provided, with the proximal end being connected to the reel of the handle. Rotation of the reel relative to the housing peels the outer sheath away from the inner stent carrier so as to move the outer sheath proximally relative to the inner stent carrier, thereby exposing the distal end of the inner stent carrier. The inner stent carrier has a stent carrying portion at its distal end to carry a stent that is deployed when the distal end of the inner stent carrier is exposed.
摘要翻译：支架引入装置包括具有壳体和可旋转卷轴的把手。提供具有近端和远端的内部支架载体，其中近端连接到手柄的外壳。提供了可移动地围绕内部支架托架设置并且具有近端和远端的外护套，其近端连接到手柄的卷轴。卷轴相对于壳体的旋转将外护套远离内支架托架剥离，以便相对于内支架托架向外侧移动外护套，从而暴露内支架托架的远端。内部支架载体在其远端具有支架承载部分，以承载当内部支架载体的远端暴露时展开的支架。

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