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1. 发明专利

JP2013132240A Cell separation device and centrifugal separation method 有权
标题翻译：细胞分离装置和离心分离方法
公开(公告)号：JP2013132240A
公开(公告)日：2013-07-08
申请号：JP2011284381
申请日：2011-12-26
申请人： Otsuka Pharmaceut Factory Inc , 株式会社大塚製薬工場 , National Cerebral & Cardiovascular Center , 独立行政法人国立循環器病研究センター
发明人： TAGUCHI AKIHIKO , YAMAHARA KENICHI , SUMIYOSHI NOBUAKI , OTANI SHINGO , WADA KEIKI , ARATA TOMOHIRO
IPC分类号： C12M1/10
摘要： PROBLEM TO BE SOLVED: To provide a cell separation device which can easily stratify without disarranging the interface of a sample on stratification, and can recover a target substance in good impurity, while preventing the mixing of the separated target substance, and to provide a centrifugal separation method.SOLUTION: The cell separation device equipped with the first container 11 having the first liquid-receiving portion 51 and the second container 12 having the second liquid-receiving portion 52 and disposed under the first container 11 in a relatively rotatable state is characterized by having the first switch mechanism 55 which can relatively rotate the first container 11 and the second container 12, thereby enabling to switch into a communication state for communicating the first liquid-receiving portion 51 with the second liquid-receiving portion 52 or into an interception state for intercepting the communication.
摘要翻译：要解决的问题：提供一种细胞分离装置，其可以容易地分层而不使分层的样品界面混杂，并且可以在防止分离的目标物质的混合的同时回收良好的杂质的目标物质，并提供离心分离方法。解决方案：具有第一容器11的细胞分离装置具有第一液体接收部分51和具有第二液体接收部分52的第二容器12并且被设置在第一容器11的相对旋转状态下通过具有可相对旋转第一容器11和第二容器12的第一开关机构55，从而能够切换到用于使第一液体接收部51与第二液体接收部52连通或连接到截取的连通状态截取通信状态。

2. 发明专利

JP2013132241A Cell separation device 审中-公开
标题翻译：细胞分离装置
公开(公告)号：JP2013132241A
公开(公告)日：2013-07-08
申请号：JP2011284382
申请日：2011-12-26
申请人： Otsuka Pharmaceut Factory Inc , 株式会社大塚製薬工場 , National Cerebral & Cardiovascular Center , 独立行政法人国立循環器病研究センター
发明人： TAGUCHI AKIHIKO , YAMAHARA KENICHI , SUMIYOSHI NOBUAKI , OTANI SHINGO , WADA KEIKI , ARATA TOMOHIRO
IPC分类号： C12M1/10
CPC分类号： C12M47/02
摘要： PROBLEM TO BE SOLVED: To provide a cell separation device which can easily stratify without disarranging the interface of sample on stratification, and can prevent the mixing of a separated target substance to recover the target substance in good purity.SOLUTION: The cell separation device has the first container 11 having the first liquid-receiving portion 51, the second container 12 having the second liquid-receiving portion 52 and disposed under the first container 11, and a communication member 20 disposed between the first container 11 and the second container 12 and having the first needle 72 extended toward the first liquid-receiving portion 51 and the second needle 73 communicating with the first needle 72 and extended toward the second liquid-receiving portion 52. The cell separation device further has a switch mechanism 55 which can switch into a communication state for communicating the first liquid-receiving portion 51 with the second liquid-receiving portion 52 through the communication member 20 or into an interception state for intercepting the communication, by the approach of the first container 11 to the second container 12 or the separation of the first container 11 from the second container 12.
摘要翻译：要解决的问题：提供一种细胞分离装置，其可以容易地分层而不使分层的样品界面混乱，并且可以防止分离的目标物质的混合以高纯度回收目标物质。解决方案：细胞分离装置具有第一容器11具有第一液体接收部分51，第二容器12具有第二液体接收部分52并且设置在第一容器11下方;以及连通构件20，设置在第一容器11和第二容器12之间，第一针72朝向第一液体接收部51延伸，第二针73与第一针72连通并朝向第二液体接收部52延伸。细胞分离装置还具有切换到用于使第一液体接收部分51与第二液体接收部分52通过的连通状态通过第一容器11到第二容器12的接近或将第一容器11与第二容器12分离的方式，进入用于截取通信的拦截状态。

3. 发明专利

JP2012031070A Method and device for preserving tissue 审中-公开
标题翻译：用于保存组织的方法和装置
公开(公告)号：JP2012031070A
公开(公告)日：2012-02-16
申请号：JP2010169618
申请日：2010-07-28
申请人： Otsuka Pharmaceut Factory Inc , 株式会社大塚製薬工場
发明人： KOBAYASHI EIJI , KIKUCHI KENJI , ARATA TOMOHIRO , YAMAOKA IPPEI
IPC分类号： A01N1/02
摘要： PROBLEM TO BE SOLVED: To provide a method for preserving tissue while keeping the tissue in a further good condition and, in particular, to provide a preservation method of tissue hardly influenced by preservation temperature.SOLUTION: This preservation method of tissue includes preserving of tissue in a tissue preservation liquid at 10-40°C while performing gas exchange of the tissue preservation liquid by photosynthesis by photosynthetic microorganisms. In the method, a culture solution including photosynthetic microorganisms and the tissue preservation liquid are joined to each other through a breathable sheet; oxygen produced by photosynthesis of the photosynthetic microorganisms moves into the tissue preservation liquid through the breathable sheet from the culture solution including the photosynthetic microorganisms; carbon dioxide included in the tissue preservation liquid moves into the culture solution including the photosynthetic microorganisms through the breathable sheet from the tissue preservation liquid; and thereby the gas exchange of the tissue preservation liquid is performed.
摘要翻译：待解决的问题：提供一种保持组织的方法，同时保持组织处于更好的状态，特别是提供几乎不受保存温度影响的组织的保存方法。解决方案：组织的这种保存方法包括在10-40℃的组织保存液中保存组织，同时通过光合微生物的光合作用进行组织保存液体的气体交换。在该方法中，包含光合微生物和组织保存液的培养液通过透气片彼此接合，由光合微生物的光合作用产生的氧通过透气片从包含光合微生物的培养液移入组织保存液中; 包含在组织保存液中的二氧化碳通过来自组织保存液的透气片移入含有光合微生物的培养液中; 从而进行组织保存液体的气体交换。版权所有（C）2012，JPO＆INPIT

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