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1. 发明授权

US06423022B1 Blood purification apparatus 有权
标题翻译：血液净化装置
公开(公告)号：US06423022B1
公开(公告)日：2002-07-23
申请号：US09310994
申请日：1999-05-13
申请人： Otfried Roeher , Steffen Korth , Friedrich A. Mueller , Dieter Rath
发明人： Otfried Roeher , Steffen Korth , Friedrich A. Mueller , Dieter Rath
IPC分类号： A61M3700
CPC分类号： G05B13/0275 , A61M1/16 , A61M2230/30 , Y10S706/924 , A61M2230/005
摘要： The ultrafiltration rate of a blood purification apparatus is controlled by a fuzzy control device in dependence on the patient's (16) blood pressure measured by a blood pressure monitor (24). For this purpose the blood pressure (P), a short-term blood pressure trend value (TRK) and a long-term blood pressure trend value (TRL) are fed as input variables for the fuzzy controller to the control device (23). The ultrafiltration rate (UFR) is determined by the volumetric ultrafiltration pump (36). According to the patient's (16) blood pressure situation a prestored profile of the ultrafiltration rate is modified. This avoids the necessity of an additional infusion to prevent too strong a blood pressure decrease.
摘要翻译：血液净化装置的超滤速度由模糊控制装置根据由血压计（24）测得的患者血压（16）来控制。为此，将血压（P），短期血压趋势值（TRK）和长期血压趋势值（TRL）作为模糊控制器作为控制装置（23）的输入变量进行输入。超滤速率（UFR）由体积超滤泵（36）确定。根据患者的（16）血压情况，预先设定的超滤速率曲线被修改。这避免了需要额外的输液以防止血压过低降低。

2. 发明授权

US5503624A Infusion system with control device 失效
标题翻译：输液系统带控制装置
公开(公告)号：US5503624A
公开(公告)日：1996-04-02
申请号：US372811
申请日：1994-12-23
申请人： Otfried Roeher , Roberto Belke , Steffen Korth
发明人： Otfried Roeher , Roberto Belke , Steffen Korth
IPC分类号： A61M5/00 , A61M5/172 , A61M31/00
CPC分类号： A61M5/1723
摘要： The infusion system is provided with a control device (10) wherein a plurality of influence factors with different physiological action mechanisms, i.e. a plurality of semantic domains, is considered as fuzzy information in the automatic dosing of drugs and the semantic significance of the individual domains is taken into account. The control device (10) for controlling at least one infusion apparatus (21) comprises a plurality of fuzzy control units (17,19) structured in a hierarchical system. On a first hierarchical levels, all linguistic variables, measurement values and derived values are examined by a semantic analyzer (16) with regard to the significance of their contents for the various semantic domains. In a unit (18) for evaluation of semantic domains, the results of the above examination are passed through a plurality of evaluation stages to draw conclusions on the operation on a second hierarchical level on which each semantic domain is represented by a fuzzy control unit (19) of its own. By the continuous semantic analysis on the first hierarchical level and the selective controlling of the fuzzy control units (19) on the second hierarchical level, the qualitatively different components of influence as well as the changes in the patient's condition occurring during the treatment, are reliably interpreted in their complex interaction and corresponding to their semantic significance and are included in the automatic dosing of drugs.
摘要翻译：输注系统设置有控制装置（10），其中具有不同生理作用机制（即，多个语义域）的多个影响因素被认为是药物自动给药中的模糊信息和各个域的语义意义被考虑在内。用于控制至少一个输注装置（21）的控制装置（10）包括以分层系统构造的多个模糊控制单元（17,19）。在第一层次上，关于其内容对于各种语义域的重要性，语义分析器（16）检查所有语言变量，测量值和派生值。在用于评估语义域的单元（18）中，上述检查的结果通过多个评估阶段来得出关于每个语义域由模糊控制单元表示的第二层级上的操作的结论（ 19）自己的。通过对第一层次的连续语义分析和对第二层次的模糊控制单元（19）的选择性控制，影响的质量不同的组成部分以及治疗期间发生的患者状况的变化是可靠的在其复杂的相互作用中解释并对应于其语义意义，并被纳入药物的自动计量。

3. 发明授权

US07775986B2 Therapy device with a time-variable blood regulation 有权
标题翻译：具有时间变化的血液调节的治疗装置
公开(公告)号：US07775986B2
公开(公告)日：2010-08-17
申请号：US11786261
申请日：2007-04-10
申请人： Otfried Roeher , Steffen Korth
发明人： Otfried Roeher , Steffen Korth
IPC分类号： A61B5/02
CPC分类号： A61M1/34 , A61M1/36 , A61M2205/3331
摘要： A therapy device having a blood pressure device and a regulating device for a time-variable regulation of the blood pressure, which decides, during a therapy procedure, dependent on detected blood pressure value, whether the blood regulation is continued with hypothetical or with real blood pressure values. The regulating device processes various categories of blood pressure values, i.e. blood pressure values obtained by the regulating device according to an implemented time schedule, blood pressure values requested by measurement and evaluation device, and blood pressure values requested by medical staff. Besides the regular triggers (RT) generated at regular intervals, the irregular triggers (IRT) and the quasi-regular triggers (QRT) requested externally at respective times are also evaluated.
摘要翻译：一种治疗装置，其具有血压装置和用于对血压进行时间变化调节的调节装置，其在治疗过程中决定于检测到的血压值，血管调节是以假血还是以真血持续压力值。调节装置根据实施的时间表，由测量和评价装置要求的血压值和医疗人员要求的血压值，处理各种血压值，即由调节装置得到的血压值。除了定期产生的常规触发（RT）外，还评估了在不同时间从外部请求的不规则触发（IRT）和准常规触发（QRT）。

4. 发明申请

US20090112102A1 Therapy device with a time-variable blood regulation 有权
标题翻译：具有时间变化的血液调节的治疗装置
公开(公告)号：US20090112102A1
公开(公告)日：2009-04-30
申请号：US11786261
申请日：2007-04-10
申请人： Otfried Roeher , Steffen Korth
发明人： Otfried Roeher , Steffen Korth
IPC分类号： A61B5/021
CPC分类号： A61M1/34 , A61M1/36 , A61M2205/3331
摘要： A therapy device having a blood pressure device and a regulating device for a time-variable regulation of the blood pressure, which decides, during a therapy procedure, dependent on detected blood pressure value, whether the blood regulation is continued with hypothetical or with real blood pressure values. The regulating device processes various categories of blood pressure values, i.e. blood pressure values obtained by the regulating device according to an implemented time schedule, blood pressure values requested by measurement and evaluation device, and blood pressure values requested by medical staff. Besides the regular triggers (RT) generated at regular intervals, the irregular triggers (IRT) and the quasi-regular triggers (QRT) requested externally at respective times are also evaluated.
摘要翻译：一种治疗装置，其具有血压装置和用于对血压进行时间变化调节的调节装置，其在治疗过程中决定于检测到的血压值，血管调节是以假血还是以真血持续压力值。调节装置根据实施的时间表，由测量和评价装置要求的血压值和医疗人员要求的血压值，处理各种血压值，即由调节装置得到的血压值。除了定期产生的常规触发（RT）外，还评估了在不同时间从外部请求的不规则触发（IRT）和准常规触发（QRT）。

5. 发明申请

US20100016776A1 TREATMENT DEVICE WITH MEMORY-SUPPORTED CONTROL MEANS 有权
标题翻译：具有记忆支持控制手段的治疗装置
公开(公告)号：US20100016776A1
公开(公告)日：2010-01-21
申请号：US12441176
申请日：2007-09-11
申请人： Otfried Röher , Steffen Korth
发明人： Otfried Röher , Steffen Korth
IPC分类号： A61M37/00 , A61B5/02
CPC分类号： A61M1/3639 , A61M1/34 , A61M1/3403 , A61M1/341 , A61M2205/3344 , A61M2205/52 , A61M2230/30 , A61M2230/005
摘要： The therapy device stores the time profiles of the blood pressure and of other influencing variables during preceding therapy procedures. The time profile of the blood pressure and of other influencing variables during the actual therapy is also recorded. An analytical comparison is then made between the time profiles of the blood pressure and of other influencing variables during the actual measurement procedure and those during preceding therapy procedures. Depending on the comparison, a prospective blood pressure control is carried out in order to prevent drops in blood pressure in a subsequent time period.
摘要翻译：治疗装置在以前的治疗过程中存储血压和其他影响变量的时间曲线。还记录了实际治疗期间血压和其他影响因素的时间特征。然后在实际测量过程中的血压时间曲线和其他影响因素之间进行分析比较，以及在之前的治疗过程中。根据比较，进行预期的血压控制以便在随后的时间段内防止血压下降。

6. 发明授权

US08556819B2 Treatment device with memory-supported control means 有权
标题翻译：具有记忆支持控制装置的处理装置
公开(公告)号：US08556819B2
公开(公告)日：2013-10-15
申请号：US12441176
申请日：2007-09-11
申请人： Otfried Röher , Steffen Korth
发明人： Otfried Röher , Steffen Korth
IPC分类号： A61B5/02 , B01D11/00 , B01D61/00
CPC分类号： A61M1/3639 , A61M1/34 , A61M1/3403 , A61M1/341 , A61M2205/3344 , A61M2205/52 , A61M2230/30 , A61M2230/005
摘要： The therapy device stores the time profiles of the blood pressure and of other influencing variables during preceding therapy procedures. The time profile of the blood pressure and of other influencing variables during the actual therapy is also recorded. An analytical comparison is then made between the time profiles of the blood pressure and of other influencing variables during the actual measurement procedure and those during preceding therapy procedures. Depending on the comparison, a prospective blood pressure control is carried out in order to prevent drops in blood pressure in a subsequent time period.
摘要翻译：治疗装置在以前的治疗过程中存储血压和其他影响变量的时间曲线。还记录了实际治疗期间血压和其他影响因素的时间特征。然后在实际测量过程中的血压时间曲线和其他影响因素之间进行分析比较，以及在之前的治疗过程中。根据比较，进行预期的血压控制以便在随后的时间段内防止血压下降。

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