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1. 发明授权

US5475089A Thrombolytic peptide, production thereof, and thrombolytic agent 失效
标题翻译：溶血肽，其制备和溶栓剂
公开(公告)号：US5475089A
公开(公告)日：1995-12-12
申请号：US75545
申请日：1993-06-14
申请人： Osamu Matsuo , Masashi Sakai , Kisaku Shimura , Hiroshi Sansawa , Tsunekazu Watanabe , Tsuneo Matsumoto , Yoshiyuki Shishido , Shusuke Hashimoto , Teruo Yokokura , Masaharu Onoue , Tomoyuki Sako
发明人： Osamu Matsuo , Masashi Sakai , Kisaku Shimura , Hiroshi Sansawa , Tsunekazu Watanabe , Tsuneo Matsumoto , Yoshiyuki Shishido , Shusuke Hashimoto , Teruo Yokokura , Masaharu Onoue , Tomoyuki Sako
IPC分类号： A61K38/46 , C07K14/31 , C12N9/52 , A61K38/43 , C07K14/00
CPC分类号： C07K14/31
摘要： A thrombolytic peptide composed of 136 amino acids residues, which has little problems of antigenicity and is efficacious in only small doses as compared with staphylokinase (SAK). This peptide is obtained by cleaving amino acids or peptides which do not affect the activity of SAK by using a trypsin protease. In particular, SAK-11, which is obtained by cleaving a peptide composed of ten amino acid residues at the N-terminal of SAK, is superior to SAK in the fibrinolysis, plasminogen activation, and fibrin specificity.
摘要翻译： PCT No.PCT / JP91 / 01722 Sec。 371日期：1993年6月14日 102（e）日期1993年6月14日PCT 1991年12月17日PCT公布。出版物WO92 / 11356 日期：1992年7月9日。一种由136个氨基酸残基组成的血栓溶解肽，与葡萄球菌激酶（SAK）相比，其抗原性问题很小，仅有小剂量有效。通过使用胰蛋白酶蛋白酶切割不影响SAK活性的氨基酸或肽来获得该肽。特别地，通过在SAK的N末端切割由10个氨基酸残基构成的肽获得的SAK-11在纤维蛋白溶解，纤溶酶原激活和纤维蛋白特异性方面优于SAK。

2. 发明授权

US4271967A System for sorting elongated members 失效
标题翻译：用于分选细长构件的系统
公开(公告)号：US4271967A
公开(公告)日：1981-06-09
申请号：US16692
申请日：1979-02-28
申请人： Osamu Matsuo , Keijiro Nakamura , Toshimi Kodaira
发明人： Osamu Matsuo , Keijiro Nakamura , Toshimi Kodaira
IPC分类号： B07C5/10 , B07C5/04
CPC分类号： B07C5/10
摘要： A system of sorting elongated pieces such as asparagus, wherein each of the elongated pieces are successively conveyed by a conveyer and detected as a still image by a sensor such as a TV camera. In processing a signal representative of the still image a stem diameter of the piece and a ratio of the spike maximum diameter of the piece to the stem diameter are obtained as sorting out factors by calculation. When the calculation values of the sorting out factors satisfy predetermined reference values, the piece is further sorted out according to size. The stem diameter is measured at a position which is spaced from the cut end of the stem by a predetermined dimension toward the spike thereof.
摘要翻译：一种分类细长片如芦笋的系统，其中每个细长片由输送机连续传送，并通过诸如TV摄像机的传感器检测为静止图像。在处理表示静止图像的信号时，通过计算获得片的茎直径和片的尖峰最大直径与茎直径的比值作为分类因子。当排序因子的计算值满足预定的参考值时，根据大小进一步整理该片段。杆直径在与杆的切割端部间隔开预定尺寸朝向其尖端的位置处测量。

3. 发明授权

US5711238A Overlock sewing machine 失效
标题翻译：包缝机
公开(公告)号：US5711238A
公开(公告)日：1998-01-27
申请号：US610915
申请日：1996-03-05
申请人： Osamu Matsuo , Yoshikazu Suzuki
发明人： Osamu Matsuo , Yoshikazu Suzuki
IPC分类号： D05B1/20 , D05B19/16 , D05B47/02 , D05B47/04
CPC分类号： D05B47/02 , D05B1/20 , D05B19/16
摘要： An overlock sewing machine which can switch its operation from an ordinary over-edge chain stitch to a rolled seam or vice versa with no requirement for a complicated operation of adjusting thread tension is obtained. This overlock sewing machine is provided with a spring for providing a thread with prescribed tension. The overlock sewing machine is further provided with a switching mechanism for switching the thread tension between that for the rolled seam and that for the over-edge chain stitch by switching the spring between a tensioning state and a non-tensioning state. Thus, the thread tension is readily switched between that for the rolled seam and that for the over-edge chain stitch.
摘要翻译：可以获得一种能够将操作从普通的上边缘缝合切换到轧制接缝或反之亦然的缝纫缝纫机，而不需要调整线张力的复杂操作。该套缝纫机设置有用于提供具有规定张力的线的弹簧。包缝机还具有切换机构，用于通过在张紧状态和非张紧状态之间切换弹簧来切换用于轧制接缝的线张力和用于超边缘链式线迹的线张力。因此，线张力容易地在轧制接缝和用于超边缘链式线迹的位置之间切换。

4. 发明授权

US4752603A Plasminogen activator and pharmaceutical composition having thrombolytic activity 失效
标题翻译：纤溶酶原激活剂和具有溶栓活性的药物组合物
公开(公告)号：US4752603A
公开(公告)日：1988-06-21
申请号：US867561
申请日：1986-05-28
申请人： Desire J. Collen , Dingeman C. Rijken , Osamu Matsuo
发明人： Desire J. Collen , Dingeman C. Rijken , Osamu Matsuo
IPC分类号： C12N9/64 , A61K38/00 , A61K38/46 , A61P7/02 , C12N9/72 , C12R1/91 , A61K37/00
CPC分类号： C12N9/6459 , C12Y304/21069 , A61K38/00 , Y10S530/828
摘要： A new plasminogen activator which is very similar to the plasminogen activator from blood can be isolated in good amounts from the culture fluid of human melanoma cells.This new plasminogen activator has a strong thrombolytic effect and pharmaceutical compositions thereof may be used in the therapeutic treatment of thrombosis disorders.
摘要翻译：与血液中的纤溶酶原激活物非常相似的新型纤溶酶原激活剂可以从人黑素瘤细胞的培养液中分离得很多。这种新的纤溶酶原激活剂具有很强的血栓溶解作用，其药物组合物可用于治疗血栓形成障碍。

5. 发明授权

US5806448A Overlock sewing machine 失效
标题翻译：包缝机
公开(公告)号：US5806448A
公开(公告)日：1998-09-15
申请号：US750193
申请日：1996-11-27
申请人： Osamu Matsuo , Yoshikazu Suzuki
发明人： Osamu Matsuo , Yoshikazu Suzuki
IPC分类号： D05B47/02 , D05B1/14 , D05B47/04
CPC分类号： D05B47/02
摘要： An overlock sewing machine which can readily form a rolled seam with no requirement for a complicated tension adjusting operation is disclosed. In this overlock sewing machine, an auxiliary thread tensioner (15) is provided independently of a main thread tensioner (4), providing a lower looper thread (9) with thread tension which is necessary for forming an over-edge chain stitch, in the vicinity thereof. An end cam (25) is provided on a shaft (13) of a dial (12) for feed adjustment, so that an upper pawl (23) rams one portion of the peripheral edge of a tension disc (20) and expands a side which is opposed thereto for canceling tension provision to the lower looper thread (9) passed through tension discs and provides the tension only by the main thread tensioner (4) to carry out an ordinary over-edge chain stitch when a lower pawl (24) is engaged with a high lift part of the end cam (25). In a rolled seam, the lower pawl (24) is engaged with a lower lift part of the end cam (25) by a rotational operation of the dial (12), and the upper pawl (23) is detached from the tension disc (20). Thus, tension which is provided by the auxiliary thread tensioner (15) in addition to the main thread tensioner (4) is applied to the lower looper thread (9), and it is not necessary to carry out tension adjustment in switching between the over-edge chain stitch and the rolled seam.
摘要翻译： PCT No.PCT / JP95 / 00588 Sec。 371日期：1996年11月27日 102（e）日期1996年11月27日PCT 1995年3月29日PCT公布。出版物WO96 / 30579 日期：1996年10月3日公开了一种能够容易地形成轧制接缝而不需要复杂的张力调节操作的包缝机。在这种缝合缝纫机中，辅助线张紧器（15）独立于主线张紧器（4）设置，在下一个弯针线（9）中形成有用于形成上边缘链式线迹所需的线张力附近。在用于进给调节的表盘（12）的轴（13）上设置端部凸轮（25），使得上棘爪（23）将张力盘（20）的周边的一部分拉伸并使一侧其相对于其用于抵消通过张紧盘的下弯针线（9）的张力提供，并且仅当下拉爪（24）向主螺纹张紧器（4）提供张力，以执行普通的上边缘链式线迹，与端部凸轮（25）的高升高部分接合。在轧制接缝中，下爪（24）通过转盘（12）的旋转操作与端凸轮（25）的下提升部分接合，并且上棘爪（23）从张紧盘 20）。因此，除了主线张紧器（4）之外由辅助线张紧器（15）提供的张力被施加到下弯针线（9），并且不需要在切换过程中进行张力调节针链缝和轧制缝。

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