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1. 发明申请

US20070259394A1 Substrate for Cell Culture, Producing Method Thereof and Screening Method for Cell Culture Conditions Utilizing the Same 有权
标题翻译：细胞培养基质，其制备方法及使用该细胞培养条件的筛选方法
公开(公告)号：US20070259394A1
公开(公告)日：2007-11-08
申请号：US10582099
申请日：2004-12-13
申请人： Osamu Kanome , Kohei Watanabe , Takeshi Miyazaki , Tomoyo Fujiyama , Byoichi Matsuda
发明人： Osamu Kanome , Kohei Watanabe , Takeshi Miyazaki , Tomoyo Fujiyama , Byoichi Matsuda
IPC分类号： G01N1/30 , C12M3/00 , C12N1/00 , C12Q1/00
CPC分类号： C12N5/0068 , C12M23/12 , C12M23/34 , C12N2501/105 , C12N2501/115 , C12N2501/155 , C12N2533/30 , C12N2533/32 , C12Q1/045
摘要： A cell culture substrate having at least one area for culturing a cell on a substrate, characterized in that the culturing area comprises an area releasably holding a biologically active substance having a biological activity to the cell and an area for immobilizing a biologically active substance having a biological activity to the cell.
摘要翻译：一种细胞培养基质，具有至少一个用于在基质上培养细胞的区域，其特征在于，培养区域包括可释放地保持对细胞具有生物活性的生物活性物质的区域和用于固定具有生物活性物质的区域对细胞的生物活性。

2. 发明申请

US20100151510A1 SUBSTRATE FOR CELL CULTURE, PRODUCING METHOD THEREOF AND SCREENING METHOD FOR CELL CULTURE CONDITIONS UTILIZING THE SAME 有权
标题翻译：用于细胞培养的基质，生产其方法和使用其的细胞培养条件的筛选方法
公开(公告)号：US20100151510A1
公开(公告)日：2010-06-17
申请号：US12711212
申请日：2010-02-23
申请人： Osamu Kanome , Kohei Watanabe , Takeshi Miyazaki , Tomoyo Fujiyama , Ryoichi Matsuda
发明人： Osamu Kanome , Kohei Watanabe , Takeshi Miyazaki , Tomoyo Fujiyama , Ryoichi Matsuda
IPC分类号： C12Q1/06 , C12M1/22 , C12Q1/02 , G01N1/30
CPC分类号： C12N5/0068 , C12M23/12 , C12M23/34 , C12N2501/105 , C12N2501/115 , C12N2501/155 , C12N2533/30 , C12N2533/32 , C12Q1/045
摘要： A cell culture substrate having at least one area for culturing a cell on a substrate, characterized in that the culturing area comprises an area releasably holding a biologically active substance having a biological activity to the cell and an area for immobilizing a biologically active substance having a biological activity to the cell.
摘要翻译：一种细胞培养基质，具有至少一个用于在基质上培养细胞的区域，其特征在于，培养区域包括可释放地保持对细胞具有生物活性的生物活性物质的区域和用于固定具有生物活性物质的区域对细胞的生物活性。

3. 发明授权

US08148153B2 Substrate for cell culture, producing method thereof and screening method for cell culture conditions utilizing the same 有权
公开(公告)号：US08148153B2
公开(公告)日：2012-04-03
申请号：US12711212
申请日：2010-02-23
申请人： Osamu Kanome , Kohei Watanabe , Takeshi Miyazaki , Tomoyo Fujiyama , Ryoichi Matsuda
发明人： Osamu Kanome , Kohei Watanabe , Takeshi Miyazaki , Tomoyo Fujiyama , Ryoichi Matsuda
IPC分类号： C12N5/00
CPC分类号： C12N5/0068 , C12M23/12 , C12M23/34 , C12N2501/105 , C12N2501/115 , C12N2501/155 , C12N2533/30 , C12N2533/32 , C12Q1/045
摘要： A cell culture substrate having at least one area for culturing a cell on a substrate, characterized in that the culturing area comprises an area releasably holding a biologically active substance having a biological activity to the cell and an area for immobilizing a biologically active substance having a biological activity to the cell.

4. 发明授权

US07960168B2 Biologically active substance transfer sheet, cell culture kit constituted of cell culture plate and biologically active substance transfer sheet, producing method thereof and method for screening cell culture conditions utilizing the same 有权
标题翻译：生物活性物质转移片，由细胞培养板和生物活性物质转移片构成的细胞培养试剂盒，其生产方法和使用其的细胞培养条件的筛选方法
公开(公告)号：US07960168B2
公开(公告)日：2011-06-14
申请号：US12183008
申请日：2008-07-30
申请人： Kohei Watanabe , Takeshi Miyazaki , Osamu Kanome , Ryoichi Matsuda , Tomoyo Fujiyama
发明人： Kohei Watanabe , Takeshi Miyazaki , Osamu Kanome , Ryoichi Matsuda , Tomoyo Fujiyama
IPC分类号： C12M1/34
CPC分类号： C12M23/12 , B01L3/0244 , B01L3/0262 , B01L3/0293 , B01L3/50853 , B01L2300/0812 , B01L2300/0829 , B01L2300/123 , C12M23/38 , C12M29/04 , C12Q1/02 , G01N33/5005
摘要： The invention provides a biologically active substance transfer sheet which can be formed with simple steps, a cell culture kit which comprises a cell culture plate and a biologically active substance transfer sheet, a producing method therefor, and a method for screening cell culture conditions with cells. The transfer sheet is prepared by providing biologically active substances having biological activity in plural areas on a sheet base, and biologically active substances are supplied from the sheet to culture regions provided on the plate.
摘要翻译：本发明提供一种生物活性物质转移片，其可以用简单的步骤形成，细胞培养试剂盒包括细胞培养板和生物活性物质转移片，其生产方法和用细胞筛选细胞培养条件的方法。通过在片材基底上的多个区域提供具有生物活性的生物活性物质来制备转印片，并且将生物活性物质从片材供给到设置在板上的培养区域。

5. 发明授权

US07419820B2 Transfer sheet for transferring biologically active substance to culture plate 有权
标题翻译：将生物活性物质转移到培养皿中的转移片
公开(公告)号：US07419820B2
公开(公告)日：2008-09-02
申请号：US10554211
申请日：2004-12-16
申请人： Kohei Watanabe , Takeshi Miyazaki , Osamu Kanome , Ryoichi Matsuda , Tomoyo Fujiyama
发明人： Kohei Watanabe , Takeshi Miyazaki , Osamu Kanome , Ryoichi Matsuda , Tomoyo Fujiyama
IPC分类号： C12M3/00
CPC分类号： C12M23/12 , B01L3/0244 , B01L3/0262 , B01L3/0293 , B01L3/50853 , B01L2300/0812 , B01L2300/0829 , B01L2300/123 , C12M23/38 , C12M29/04 , C12Q1/02 , G01N33/5005
摘要： The invention provides a biologically active substance transfer sheet which can be formed with simple steps, a cell culture kit which comprises a cell culture plate and a biologically active substance transfer sheet, a producing method therefor, and a method for screening cell culture conditions with cells. The transfer sheet is prepared by providing biologically active substances having biological activity in plural areas on a sheet base, and biologically active substances are supplied from the sheet to culture regions provided on the plate.
摘要翻译：本发明提供一种生物活性物质转移片，其可以用简单的步骤形成，细胞培养试剂盒包括细胞培养板和生物活性物质转移片，其生产方法和用细胞筛选细胞培养条件的方法。通过在片材基底上的多个区域提供具有生物活性的生物活性物质来制备转印片，并且将生物活性物质从片材供给到设置在板上的培养区域。

6. 发明申请

US20080293138A1 BIOLOGICALLY ACTIVE SUBSTANCE TRANSFER SHEET, CELL CULTURE KIT CONSTITUTED OF CELL CULTURE PLATE AND BIOLOGICALLY ACTIVE SUBSTANCE TRANSFER SHEET, PRODUCING METHOD THEREOF AND METHOD FOR SCREENING CELL CULTURE CONDITIONS UTILIZING THE SAME 有权
标题翻译：生物活性物质转移片，细胞培养板和生物活性物质转移片的细胞培养试剂盒，生产方法和筛选使用其的细胞培养条件的方法
公开(公告)号：US20080293138A1
公开(公告)日：2008-11-27
申请号：US12183008
申请日：2008-07-30
申请人： Kohei Watanabe , Takeshi Miyazaki , Osamu Kanome , Ryoichi Matsuda , Tomoyo Fujiyama
发明人： Kohei Watanabe , Takeshi Miyazaki , Osamu Kanome , Ryoichi Matsuda , Tomoyo Fujiyama
IPC分类号： C12M3/00 , C12M3/02 , C12N5/02
CPC分类号： C12M23/12 , B01L3/0244 , B01L3/0262 , B01L3/0293 , B01L3/50853 , B01L2300/0812 , B01L2300/0829 , B01L2300/123 , C12M23/38 , C12M29/04 , C12Q1/02 , G01N33/5005
摘要： The invention provides a biologically active substance transfer sheet which can be formed with simple steps, a cell culture kit which comprises a cell culture plate and a biologically active substance transfer sheet, a producing method therefor, and a method for screening cell culture conditions with cells. The transfer sheet is prepared by providing biologically active substances having biological activity in plural areas on a sheet base, and biologically active substances are supplied from the sheet to culture regions provided on the plate.
摘要翻译：本发明提供一种生物活性物质转移片，其可以用简单的步骤形成，细胞培养试剂盒包括细胞培养板和生物活性物质转移片，其生产方法和用细胞筛选细胞培养条件的方法。通过在片材基底上的多个区域提供具有生物活性的生物活性物质来制备转印片，并且将生物活性物质从片材供给到设置在板上的培养区域。

7. 发明申请

US20060246508A1 Biologically active substance transfer sheet, cell culture kit constituted of cell culture plate and biologically active substance transfer sheet, producing method thereof and method for screening cell culture conditions utilizing the same 有权
标题翻译：生物活性物质转移片，由细胞培养板和生物活性物质转移片构成的细胞培养试剂盒，其生产方法和使用其的细胞培养条件的筛选方法
公开(公告)号：US20060246508A1
公开(公告)日：2006-11-02
申请号：US10554211
申请日：2004-12-16
申请人： Kohei Watanabe , Takeshi Miyazaki , Osamu Kanome , Ryoichi Matsuda , Tomoyo Fujiyama
发明人： Kohei Watanabe , Takeshi Miyazaki , Osamu Kanome , Ryoichi Matsuda , Tomoyo Fujiyama
IPC分类号： G01N33/53 , G01N33/567 , C12M1/34
CPC分类号： C12M23/12 , B01L3/0244 , B01L3/0262 , B01L3/0293 , B01L3/50853 , B01L2300/0812 , B01L2300/0829 , B01L2300/123 , C12M23/38 , C12M29/04 , C12Q1/02 , G01N33/5005
摘要： The invention provides a biologically active substance transfer sheet which can be formed with simple steps, a cell culture kit which comprises a cell culture plate and a biologically active substance transfer sheet, a producing method therefor, and a method for screening cell culture conditions with cells. The transfer sheet is prepared by providing biologically active substances having biological activity in plural areas on a sheet base, and biologically active substances are supplied from the sheet to culture regions provided on the plate.
摘要翻译：本发明提供一种生物活性物质转移片，其可以用简单的步骤形成，细胞培养试剂盒包括细胞培养板和生物活性物质转移片，其生产方法和用细胞筛选细胞培养条件的方法。通过在片材基底上的多个区域提供具有生物活性的生物活性物质来制备转印片，并且将生物活性物质从片材供给到设置在板上的培养区域。

8. 发明授权

US07070344B2 Production process of light amount adjustment member, light amount adjustment device and photographing apparatus 失效
标题翻译：光量调节构件，光量调节装置和拍摄装置的制作过程
公开(公告)号：US07070344B2
公开(公告)日：2006-07-04
申请号：US10872503
申请日：2004-06-22
申请人： Osamu Kanome , Ryuji Katsuragi , Takeshi Miyazaki , Ichiro Onuki , Eriko Namazue , Kohei Watanabe , Akio Kashiwazaki
发明人： Osamu Kanome , Ryuji Katsuragi , Takeshi Miyazaki , Ichiro Onuki , Eriko Namazue , Kohei Watanabe , Akio Kashiwazaki
IPC分类号： G03B9/02
CPC分类号： H04N5/2254 , G02B5/005 , G02B5/205 , G03B9/06
摘要： A light amount adjustment member, which causes little deterioration of image quality by diffraction at a grain boundary between ink dots in a colored portion, can be simply produced at low production cost and high yield. The light amount adjustment member has a density distribution such that an optical density varies continuously or stepwise. The process comprises steps of providing a transparent base material having a receptive layer comprised of a material capable of absorbing a coloring liquid and containing a resin and crosslinking agent, applying the coloring liquid to the layer using an ink-jet recording method to form a light amount adjustment region having a particular optical density region, storing the layer under a prescribed environment after application of the coloring liquid to the layer to cause dots formed by the coloring liquid to bleed and crosslinking the resin contained in the layer by the crosslinking agent.
摘要翻译：通过在彩色部分的墨点之间的晶界处的衍射，几乎不会导致图像质量劣化的光量调节部件能够以低制造成本和高产率简单地制造。光量调节构件具有使得光密度连续或逐步变化的密度分布。该方法包括提供具有由能够吸收着色液体并含有树脂和交联剂的材料构成的受体层的透明基材的步骤，使用喷墨记录方法将着色液体施加到层上以形成光量调节区域，具有特定的光密度区域，在将着色液体施加到层之后，在规定的环境下存储该层，以使由着色液体形成的点使由该交联剂渗出并交联该层中的树脂。

9. 发明申请

US20050008358A1 Production process of light amount adjustment member, light amount adjustment device and photographing apparatus 失效
标题翻译：光量调节构件，光量调节装置和拍摄装置的制作过程
公开(公告)号：US20050008358A1
公开(公告)日：2005-01-13
申请号：US10872503
申请日：2004-06-22
申请人： Osamu Kanome , Ryuji Katsuragi , Takeshi Miyazaki , Ichiro Onuki , Eriko Namazue , Kohei Watanabe , Akio Kashiwazaki
发明人： Osamu Kanome , Ryuji Katsuragi , Takeshi Miyazaki , Ichiro Onuki , Eriko Namazue , Kohei Watanabe , Akio Kashiwazaki
IPC分类号： G02B5/00 , G02B5/20 , G03B9/02 , G03B9/06 , G03B9/08 , G03B11/00 , H04N5/225
CPC分类号： H04N5/2254 , G02B5/005 , G02B5/205 , G03B9/06
摘要： A light amount adjustment member, which causes little deterioration of image quality by diffraction at a grain boundary between ink dots in a colored portion, is provided. A production process of a light amount adjustment member, by which a light amount adjustment member can be simply produced at low production cost and high yield, is also provided. A production process of a light amount adjustment member, by which a light amount adjustment member having a density distribution that an optical density varies continuously or stepwise can be simply obtained, is further provided. The production process comprises the steps of providing a transparent base material having a receptive layer composed of a material capable of absorbing a coloring liquid and applying the coloring liquid to the layer using an ink-jet recording method to form a light amount adjustment region having a particular optical density region, wherein the receptive layer contains a resin and a crosslinking agent, and the process further comprises the steps of storing the layer under a prescribed environment after the application of the coloring liquid to the layer to cause dots formed by the coloring liquid to bleed and crosslinking the resin contained in the layer by the crosslinking agent.
摘要翻译：提供了一种光量调节构件，其通过在着色部分中的墨点之间的晶界处的衍射引起的图像质量几乎不劣化。还提供了一种光量调节部件的生产过程，通过该光量调节部件，可以以低生产成本和高产量简单地生产光量调节部件。进一步提供光量调节构件的制造方法，通过该光量调节构件可以简单地获得具有光密度连续或逐步变化的密度分布的光量调节构件。制造方法包括以下步骤：提供透明基材，其具有由能够吸收着色液体的材料构成的接受层，并使用喷墨记录方法将该着色液体涂布在该层上，形成具有特定的光学密度区域，其中，所述接收层含有树脂和交联剂，所述方法还包括以下步骤：在将着色液体施加到所述层上以使得由着色液体形成的点之后，在规定的环境下储存该层通过交联剂使包含在该层中的树脂渗色和交联。

10. 发明授权

US07099555B2 Light amount adjusting apparatus, optical equipment, optical filter and image-taking apparatus 有权
标题翻译：光量调节装置，光学设备，滤光器和摄像装置
公开(公告)号：US07099555B2
公开(公告)日：2006-08-29
申请号：US10919514
申请日：2004-08-17
申请人： Ichiro Onuki , Eriko Namazue , Akio Kashiwazaki , Osamu Kanome , Kohei Watanabe
发明人： Ichiro Onuki , Eriko Namazue , Akio Kashiwazaki , Osamu Kanome , Kohei Watanabe
IPC分类号： G02B6/00
CPC分类号： G02B5/22 , G02B27/58
摘要： An optical filter is disclosed which adjusts the contours of blurred images and maintains the size of blurred images. The optical filter includes a substrate being substantially transparent and a first layer whose optical density changes continuously, formed on the substrate. A transmission rate of the first layer decreases substantially linearly from a center toward a periphery of the optical filter, and the transmission rate distribution is symmetric with respect to the center.
摘要翻译：公开了一种滤光器，其调整模糊图像的轮廓并维持模糊图像的尺寸。光学滤波器包括基本上透明的基板和形成在基板上的光密度连续变化的第一层。第一层的透射率从滤光器的中心向周边大致线性地减小，透射率分布相对于中心对称。

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