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1. 发明专利

JP2009061136A Method for biological activation of metallic glass and biologically activated metallic glass 审中-公开
标题翻译：金属玻璃和生物活性金属玻璃的生物活化方法
公开(公告)号：JP2009061136A
公开(公告)日：2009-03-26
申请号：JP2007232225
申请日：2007-09-07
申请人： Osaka Univ , Tohoku Univ , Tokyo Institute Of Technology , 国立大学法人大阪大学 , 国立大学法人東京工業大学 , 国立大学法人東北大学
发明人： YOSHIMURA MASAHIRO , ONOKI NORISHIGE , YASUDA EIICHI , WATANABE TOMOSUKE , TANABE YASUHIRO , AKAO MASARU , MATSUSHITA NOBUHIRO , SUGIYAMA NAOHIRO , HOSHIKAWA YASUTO , NAITO MAKIO , TSUKAMOTO MASAHIRO , KOMIZO YUICHI , ABE HIROYA , ABE NOBUYUKI , INOUE AKIHISA , WANG XINMIN , WADA TAKESHI , AKE KATSUTOSHI , HATA FUGA , FUKUHARA MIKIO
IPC分类号： A61L27/00
摘要： PROBLEM TO BE SOLVED: To provide a method for the biological activation of a metallic glass surface and a biologically activated metallic glass.
SOLUTION: A base metallic glass material is filled up in an autoclave for hydrothermal hot press, together with a powder of mixture of calcium II hydrate hydrogenphosphate and calcium hydroxide, and kept pressurized at a temperature of 50 to 300°C for 30 to 720 minutes. The biologically activated metallic glass manufactured by this process includes an intermediate layer between the base metallic glass material and the hydroxyapatite layer.
COPYRIGHT: (C)2009,JPO&INPIT
摘要翻译：要解决的问题：提供金属玻璃表面和生物活化金属玻璃的生物活化的方法。解决方案：将碱金属玻璃材料与用于水热热压的高压釜以及II型二水合磷酸氢钙和氢氧化钙的混合物粉末填充，并在50至300℃的温度下保持加压30 至720分钟。通过该方法制造的生物活化金属玻璃包括在基底金属玻璃材料和羟基磷灰石层之间的中间层。版权所有（C）2009，JPO＆INPIT

2. 发明专利

JP2009061135A Biological activation material 审中-公开
标题翻译：生物活性材料
公开(公告)号：JP2009061135A
公开(公告)日：2009-03-26
申请号：JP2007232224
申请日：2007-09-07
申请人： Osaka Univ , Tohoku Univ , Tokyo Institute Of Technology , 国立大学法人大阪大学 , 国立大学法人東京工業大学 , 国立大学法人東北大学
发明人： YOSHIMURA MASAHIRO , ONOKI NORISHIGE , YASUDA EIICHI , WATANABE TOMOSUKE , TANABE YASUHIRO , AKAO MASARU , MATSUSHITA NOBUHIRO , SUGIYAMA NAOHIRO , HOSHIKAWA YASUTO , NAITO MAKIO , TSUKAMOTO MASAHIRO , KOMIZO YUICHI , ABE HIROYA , ABE NOBUYUKI , INOUE AKIHISA , WANG XINMIN , WADA TAKESHI , AKE KATSUTOSHI , HATA FUGA , FUKUHARA MIKIO
IPC分类号： A61L27/00 , A61F2/28
摘要： PROBLEM TO BE SOLVED: To provide a biological activation material where the metallic glass surface of the material is firmly connected with HAp because of similarities between the network of the metallic glass surface and the network of bio-tissues, and connections with HAp are more strengthened with an oxide as roots and component of interfaces with HAp.
SOLUTION: The inner metallic glass is porous and has an elastic modulus and a high strength similar to those of human bones. The biological activation material surface made of biological ceramics having biological affinity or a material inducing it is deposited on the metallic glass surface through intermediate layers.
COPYRIGHT: (C)2009,JPO&INPIT
摘要翻译：要解决的问题：为了提供一种生物活化材料，其中材料的金属玻璃表面与HAp牢固地连接，因为金属玻璃表面的网络和生物组织的网络之间的相似性以及与HAp的连接更加强化了氧化物作为HAp接口的根和组成部分。解决方案：内金属玻璃是多孔的，并且具有类似于人骨的弹性模量和高强度。由具有生物亲和力的生物陶瓷制成的生物活化材料表面或诱导材料的材料通过中间层沉积在金属玻璃表面上。版权所有（C）2009，JPO＆INPIT

3. 发明专利

JP2010142490A Biologically activated material and method of manufacturing the same 审中-公开
标题翻译：生物活性材料及其制造方法
公开(公告)号：JP2010142490A
公开(公告)日：2010-07-01
申请号：JP2008324537
申请日：2008-12-19
申请人： Tohoku Univ , 国立大学法人東北大学
发明人： HATA FUGA , WANG XINMIN , INOUE AKIHISA , WADA TAKESHI
IPC分类号： A61L27/00
摘要： PROBLEM TO BE SOLVED: To provide a biologically activated material and a method of manufacturing the same for further accelerating deposition of biologically activated substances. SOLUTION: The surface of a metallic glass alloy 1 includes an intermediate treatment layer 2 formed in a manner to grow roots from the metallic glass alloy 1 by the GIL (growing integration layers) method. The intermediate treatment layer 2 shows affinity to living bodies and has at least one of Ca and P. The surface of the intermediate treatment layer 2 has a hydroxyapatite layer 3 growing thickly by immersing it in Hanks solution. COPYRIGHT: (C)2010,JPO&INPIT
摘要翻译：要解决的问题：提供生物活化材料及其制造方法，以进一步加速生物活化物质的沉积。解决方案：金属玻璃合金1的表面包括中间处理层2，其以通过GIL（生长积分层）方法从金属玻璃合金1生长根的方式形成。中间处理层2表现出对活体的亲和性，并且具有Ca和P中的至少一种。中间处理层2的表面具有通过将其浸入Hanks溶液中而使生长较厚的羟基磷灰石层3。版权所有（C）2010，JPO＆INPIT

4. 发明专利

JP2009052131A Ti-Cu-Zr-Pd METAL GLASS ALLOY 有权
标题翻译： Ti-Cu-Zr-Pd金属玻璃合金
公开(公告)号：JP2009052131A
公开(公告)日：2009-03-12
申请号：JP2008043996
申请日：2008-02-26
申请人： Tohoku Univ , 国立大学法人東北大学
发明人： INOUE AKIHISA , WANG XINMIN , AKE KATSUTOSHI , HATA FUGA , WADA TAKESHI
IPC分类号： C22C45/10 , C22C45/00
摘要： PROBLEM TO BE SOLVED: To provide a Ti-Cu-Zr-Pd metal glass alloy having excellent bulk formability. SOLUTION: The Ti-Cu-Zr-Pd metal glass alloy has a composition expressed by formula: Ti 100-a-b-c Cu a Zr b Pd c [wherein, a, b and c are atomic%, and, a denotes 30 to 50%, b denotes 0.5 to 20% and c denotes 0.5 to 20%]. Alternatively, the Ti-Cu-Zr-Pd metal glass alloy has a composition expressed by formula: ä(Ti 1-a-b Zr a Nb b ) 0.5 (Cu 1-c-d Pd c Ag d ) 0.5 } 100-x Si x [wherein, a, b, c and d are atomic ratio, and, a denotes 0.005 to 0.2, b denotes 0.005 to 0.1, c denotes 0.005 to 0.2 and d denotes 0.005 to 0.1, and x is an atomic%, and denotes 0.5 to 10%]. COPYRIGHT: (C)2009,JPO&INPIT
摘要翻译：要解决的问题：提供具有优异的堆积成形性的Ti-Cu-Zr-Pd金属玻璃合金。＆lt; P＆gt;解决方案：Ti-Cu-Zr-Pd金属玻璃合金具有由下式表示的组成：Ti 100-abc 其中a，b和c为原子％，a为30〜50％，b为0.5〜20％，c为0.5〜20％。或者，Ti-Cu-Zr-Pd金属玻璃合金具有由以下公式表示的组成：ä（Ti 1-ab b B ＆lt; SB＆gt; 0.5＆lt; SB＆gt;（Cu＆lt; SB＆gt; 1-cd＆lt; SB＆gt;＆lt; SB＆gt; 其中a，b，c和d是原子比，a表示0.005〜0.2，b表示0.005〜0.1，c表示0.005 为0.2，d为0.005〜0.1，x为原子％，为0.5〜10％]。版权所有（C）2009，JPO＆INPIT

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