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1. 发明申请

WO2017077526A1 HEMOSTATIC MIXTURE OF CELLULOSE-BASED SHORT AND LONG FIBERS 审中-公开
标题翻译：纤维素基短纤维和长纤维的静脉内混合物
公开(公告)号：WO2017077526A1
公开(公告)日：2017-05-11
申请号：PCT/IL2016/000020
申请日：2016-11-08
申请人： OMRIX BIOPHARMACEUTICALS LTD. , ETHICON, INC.
发明人： ILAN, Erez , FAINGOLD, Omri , FREIZUS, Nataly , EAVRI, Ronen , LOONEY, Dwayne , DHANARAJ, Sridevi , GALLOWAY, James , DANKER, Walter
IPC分类号： A61L24/06 , A61L24/04 , A61L24/00
CPC分类号： A61L26/0023 , A61L24/001 , A61L24/0015 , A61L24/02 , A61L24/043 , A61L24/06 , A61L24/08 , A61L26/00 , A61L26/0004 , A61L2300/106 , A61L2300/232 , A61L2300/25 , A61L2300/418 , A61L2300/802 , A61L2400/04 , C08L1/04
摘要： The invention relates to a hemostatic composition comprising a mixture of cellulose- based short and long fibers, preparation and use thereof.
摘要翻译：本发明涉及包含基于纤维素的短纤维和长纤维的混合物的止血组合物，其制备和使用。

2. 发明申请

WO2017077525A1 HEMOSTATIC COMPOSITION 审中-公开
标题翻译：止血组合物
公开(公告)号：WO2017077525A1
公开(公告)日：2017-05-11
申请号：PCT/IL2016/000019
申请日：2016-11-08
申请人： OMRIX BIOPHARMACEUTICALS LTD. , ETHICON, INC.
发明人： ILAN, Erez , FAINGOLD, Omri , FREIZUS, Nataly , EAVRI, Ronen , LOONEY, Dwayne , DHANARAJ, Sridevi , GALLOWAY, James , DANKER, Walter
IPC分类号： A61L24/00 , A61L24/04
CPC分类号： A61L26/0023 , A61L24/001 , A61L24/0015 , A61L24/02 , A61L24/043 , A61L24/06 , A61L24/08 , A61L26/00 , A61L26/0004 , A61L2300/106 , A61L2300/232 , A61L2300/25 , A61L2300/418 , A61L2300/802 , A61L2400/04 , C08L1/04
摘要： The present invention relates to improved hemostatic compositions comprising cellulose-based fibers supplemented with compounds, preparation and use thereof.
摘要翻译：本发明涉及包含补充有化合物的纤维素基纤维的改进的止血组合物，其制备和用途。

3. 发明公开

EP3370786A1 HEMOSTATIC MIXTURE OF CELLULOSE-BASED SHORT AND LONG FIBERS 有权
公开(公告)号：EP3370786A1
公开(公告)日：2018-09-12
申请号：EP16805906.1
申请日：2016-11-08
申请人： Omrix Biopharmaceuticals Ltd. , Ethicon, Inc.
发明人： ILAN, Erez , FAINGOLD, Omri , FREIZUS, Nataly , EAVRI, Ronen , LOONEY, Dwayne , DHANARAJ, Sridevi , GALLOWAY, James , DANKER, Walter
IPC分类号： A61L24/06 , A61L24/04 , A61L24/00
CPC分类号： A61L26/0023 , A61L24/001 , A61L24/0015 , A61L24/02 , A61L24/043 , A61L24/06 , A61L24/08 , A61L26/00 , A61L26/0004 , A61L2300/106 , A61L2300/232 , A61L2300/25 , A61L2300/418 , A61L2300/802 , A61L2400/04 , C08L1/04
摘要： The invention relates to a hemostatic composition comprising a mixture of cellulose-based short and long fibers, preparation and use thereof.

4. 发明公开

EP3370785A1 HEMOSTATIC COMPOSITION 有权
公开(公告)号：EP3370785A1
公开(公告)日：2018-09-12
申请号：EP16805220.7
申请日：2016-11-08
申请人： Omrix Biopharmaceuticals Ltd. , Ethicon, Inc.
发明人： ILAN, Erez , FAINGOLD, Omri , FREIZUS, Nataly , EAVRI, Ronen , LOONEY, Dwayne , DHANARAJ, Sridevi , GALLOWAY, James , DANKER, Walter
IPC分类号： A61L24/00 , A61L24/04
CPC分类号： A61L26/0023 , A61L24/001 , A61L24/0015 , A61L24/02 , A61L24/043 , A61L24/06 , A61L24/08 , A61L26/00 , A61L26/0004 , A61L2300/106 , A61L2300/232 , A61L2300/25 , A61L2300/418 , A61L2300/802 , A61L2400/04 , C08L1/04
摘要： The invention relates to a hemostatic composition comprising a mixture of cellulose-based short and long fibers, preparation and use thereof.

5. 发明公开

EP3868414A1 HEMOSTATIC MIXTURE OF CELLULOSE-BASED SHORT AND LONG FIBERS 有权
公开(公告)号：EP3868414A1
公开(公告)日：2021-08-25
申请号：EP21169067.2
申请日：2016-11-08
申请人： Omrix Biopharmaceuticals Ltd. , Ethicon, Inc.
发明人： ILAN, Erez , FAINGOLD, Omri , FREIZUS, Nataly , EAVRI, Ronen , LOONEY, Dwayne , DHANARAJ, Sridevi , GALLOWAY, James , DANKER, Walter
IPC分类号： A61L24/08 , A61L24/00 , A61L24/04 , A61P7/04 , A61P17/02
摘要： The invention relates to a hemostatic composition comprising a mixture of cellulosebased short and long fibers, preparation and use thereof.

6. 发明申请

WO2012020412A3 FIBRIN BASED SCAFFOLD, PREPARATION AND USE THEREOF 审中-公开
公开(公告)号：WO2012020412A3
公开(公告)日：2012-02-16
申请号：PCT/IL2011/000653
申请日：2011-08-10
申请人： OMRIX BIOPHARMACEUTICALS LTD, , ATLAS, Roee , NUR, Israel , MEIDLER. Roberto , BAR, Liliana , BUENSUCESO, Charito , KIHM, Anthony J. , DHANARAJ, Sridevi
发明人： ATLAS, Roee , NUR, Israel , MEIDLER. Roberto , BAR, Liliana , BUENSUCESO, Charito , KIHM, Anthony J. , DHANARAJ, Sridevi
IPC分类号： A61L17/00 , A61L27/22 , A61K9/00
摘要： The invention relates to a fibrin-based scaffold suitable for supporting a population of cells comprising mesenchymal stem cells (MSC) and/or umbilical tissue derived cells (UTC) at the site of administration for a prolonged period of time. The scaffold is capable of supporting at least 1 x 106 cells/ml scaffold. The invention also relates to the preparation of the scaffold and to its use. Preparation of the scaffold is carried out with a fibrinogen component comprising fibrinogen having a final concentration of higher than 17.5 mg/ml scaffold. The scaffold and the embedded MSC and/or UTC can be used for increasing vascularization and/or wound healing at the site of administration.

7. 发明授权

EP2603247B1 FIBRIN BASED SCAFFOLD, PREPARATION AND USE THEREOF 有权
标题翻译： FIBRINBASIERTES框架，生产和使用
公开(公告)号：EP2603247B1
公开(公告)日：2014-11-19
申请号：EP11764341.1
申请日：2011-08-10
申请人： Omrix Biopharmaceuticals Ltd.
发明人： ATLAS, Roee , NUR, Israel , MEIDLER. Roberto , BAR, Liliana , BUENSUCESO, Charito , KIHM, Anthony J. , DHANARAJ, Sridevi
IPC分类号： A61L17/00 , A61L27/22 , A61K9/00
CPC分类号： A61L27/225 , A61L27/3834 , C12N2533/56

8. 发明公开

EP2603247A2 FIBRIN BASED SCAFFOLD, PREPARATION AND USE THEREOF 有权
标题翻译： FIBRINBASIERTES框架，生产和使用
公开(公告)号：EP2603247A2
公开(公告)日：2013-06-19
申请号：EP11764341.1
申请日：2011-08-10
申请人： Omrix Biopharmaceuticals Ltd.
发明人： ATLAS, Roee , NUR, Israel , MEIDLER. Roberto , BAR, Liliana , BUENSUCESO, Charito , KIHM, Anthony J. , DHANARAJ, Sridevi
IPC分类号： A61L17/00 , A61L27/22 , A61K9/00
CPC分类号： A61L27/225 , A61L27/3834 , C12N2533/56
摘要： The invention relates to a fibrin-based scaffold suitable for supporting a population of cells comprising mesenchymal stem cells (MSC) and/or umbilical tissue derived cells (UTC) at the site of administration for a prolonged period of time. The scaffold is capable of supporting at least 1×106 cells/ml scaffold. The invention also relates to the preparation of the scaffold and to its use. Preparation of the scaffold is carried out with a fibrinogen component comprising fibrinogen having a final concentration of higher than 17.5 mg/ml scaffold. The scaffold and the embedded MSC and/or UTC can be used for increasing vascularization and/or wound healing at the site of administration.

9. 发明申请

WO2023079401A1 PLUG FOR LUNG TISSUE TRACT SEALING 审中-公开
公开(公告)号：WO2023079401A1
公开(公告)日：2023-05-11
申请号：PCT/IB2022/060146
申请日：2022-10-21
申请人： ETHICON, INC.
发明人： GHODBANE, Salim , DHANARAJ, Sridevi , DEANGLIS, Ashley , ZHANG, Guanghui
IPC分类号： A61L24/06 , A61L24/10 , A61L24/00
摘要： The present invention provides a tissue sealing plug comprising a substrate comprising foamed gelatin impregnated with polyethylene glycol that is liquid at room temperature, wherein the weight ratio of polyethylene glycol to foamed gelatin in the substrate is about 4:1 to about 6.8:1 and the substrate is substantially free of air, along with methods of using the plug for closing tissue punctures in the lung.

10. 发明申请

WO2017192438A1 SURGICAL STAPLER/CUTTER AND EXTENDED BUTTRESS 审中-公开
标题翻译：手术装订器/刀具和延伸扣件
公开(公告)号：WO2017192438A1
公开(公告)日：2017-11-09
申请号：PCT/US2017/030383
申请日：2017-05-01
申请人： ETHICON, INC. , ETHICON LLC
发明人： NATIV, Nir I. , DHANARAJ, Sridevi , KRIKSUNOV, Leo B. , SCHEIB, Charles J.
IPC分类号： A61B17/072
摘要： The present invention is directed to surgical staplers stapling and resecting tissue comprising a surgical buttress at least partially disposed on a tissue facing surface of at least one of the cartridge or the anvil, said buttress having width substantially larger than width of said tissue facing surfaces; said buttress comprising a first portion positioned over the deployable staples or over the staple forming pockets, and at least one flap portion not positioned over the deployable staples or over the staple forming pockets; said flap portion folded or rolled on itself and configured to be unfurlable and wrappable about the resected tissue. The present invention is also directed to methods of use of such stapler assembly devices.
摘要翻译：本发明涉及外科缝合器缝合和切除组织，其包括至少部分地设置在药筒或砧座中的至少一个的面向组织的表面上的手术支撑件，所述支撑件具有基本上更大的宽度超过所述面向组织的表面的宽度; 所述支撑件包括位于所述可展开钉上方或所述钉成形凹坑上方的第一部分以及未定位在所述可展开钉上方或所述钉成形凹坑上方的至少一个折翼部分; 所述折翼部分自身折叠或卷起并且构造成不可展开并且可围绕切除的组织卷绕。本发明还涉及这种缝合器组件装置的使用方法。

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