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1. 发明申请

US20090287066A1 METHOD FOR MINIMALLY INVASIVE MEDICAL INTERVENTION 审中-公开
标题翻译：最小的入侵医学干预方法
公开(公告)号：US20090287066A1
公开(公告)日：2009-11-19
申请号：US12122856
申请日：2008-05-19
申请人： Oliver Meissner , John Christopher Rauch , Thomas Redel , Michael Zellerhoff
发明人： Oliver Meissner , John Christopher Rauch , Thomas Redel , Michael Zellerhoff
IPC分类号： A61B5/00
CPC分类号： A61B6/481 , A61B6/4441 , A61B6/504
摘要： A workflow for a minimally invasive intervention, such as a treatment for a cancerous tumor, includes positioning a patient at a multi-functional imaging apparatus, obtaining pre-interventional images of the anatomy of the patient using a computed tomography or angiography imaging function, performing the minimally invasive intervention while the patient is positioned at the multi-functional imaging apparatus and while using a fluoroscopic imaging function, and performing a post-interventional imaging of the patient's anatomy while the patient is positioned at the multi-functional imaging apparatus using the computed tomography or angiographic imaging function. If the post-interventional imaging determines that additional intervention is in order, the additional intervention is performed while the patient is positioned at the imaging apparatus. Pre-intervention images and data sets from other sources may be combined with or used during the intervention. A treatment planning step may be included following the pre-interventional imaging and the intervention.
摘要翻译：用于微创干预的工作流程，例如用于癌性肿瘤的治疗，包括将患者定位在多功能成像装置上，使用计算机断层摄影或血管造影成像功能获得患者的解剖结构的介入前图像，执行当患者位于多功能成像设备并且同时使用荧光透视成像功能时进行微创干预，并且当患者使用计算出的多功能成像设备定位在多功能成像设备时对患者的解剖结构进行介入后成像断层扫描或血管造影成像功能。如果介入后成像确定额外干预是有序的，则在患者定位在成像装置的同时执行附加介入。来自其他来源的预干预图像和数据集可以在干预期间组合或使用。治疗计划步骤可以包括在介入前成像和干预之后。

2. 发明申请

US20110235885A1 System for Providing Digital Subtraction Angiography (DSA) Medical Images 审中-公开
标题翻译：提供数字减影血管造影（DSA）医学图像的系统
公开(公告)号：US20110235885A1
公开(公告)日：2011-09-29
申请号：US13100362
申请日：2011-05-04
申请人： John Christopher Rauch , John Baumgart
发明人： John Christopher Rauch , John Baumgart
IPC分类号： G06K9/00
CPC分类号： A61B6/504 , A61B6/4441 , A61B6/481 , G06F19/321 , G06F19/3468 , G06T15/08 , G06T2210/41
摘要： A method generates a two dimensional (2D) medical image through a three dimensional (3D) imaged volume of patient anatomy at a desired position, by storing 3D image data representing a 3D imaging volume including vessels in the presence of a contrast agent. The 3D image data comprises, data identifying multiple voxels representing multiple individual volume image element luminance values and luminance distribution data for individual voxels of a vessel in the 3D image data. For multiple individual voxels of a 2D image, the method determines composite luminance distribution data of an individual voxel in the 2D image by combining luminance distribution data of the 3D image data of multiple identified voxels substantially lying on a projection line from a source point to the individual voxel and generating data representing the 2D image using the determined composite luminance distribution data of the multiple individual voxels.
摘要翻译：方法是通过在存在造影剂的情况下存储表示包含血管的3D成像体积的3D图像数据，通过在所需位置的患者解剖结构的三维（3D）成像体积）生成二维（2D）医学图像。 3D图像数据包括：3D图像数据中识别表示多个个体体积图像单元亮度值的多个体素的数据和容器的各个体素的亮度分布数据。对于2D图像的多个个体体素，该方法通过将基本上位于从源点到投影线的投影线上的多个识别的体素的3D图像数据的亮度分布数据组合，来确定2D图像中的单个体素的合成亮度分布数据使用所确定的多个个别体素的合成亮度分布数据生成表示2D图像的数据。

3. 发明授权

US08160199B2 System for 3-dimensional medical image data acquisition 有权
标题翻译：三维医学图像数据采集系统
公开(公告)号：US08160199B2
公开(公告)日：2012-04-17
申请号：US12249652
申请日：2008-10-10
申请人： John Christopher Rauch
发明人： John Christopher Rauch
IPC分类号： A61B6/03
CPC分类号： A61B6/03 , A61B6/032 , A61B6/4458 , A61B6/4464 , A61B6/466 , A61B6/5258 , Y10S378/901
摘要： A method and system provides medical image processing and 3-dimensional image construction of an examination subject. A user is enabled to selectively orient an x-ray imaging system having a variable 3-dimensional acquisition axis relative to an examination subject support for holding an examination subject. A non-planar image data acquisition path is set for the x-ray imaging system oriented around the variable 3-dimensional acquisition axis in response to user instruction. Acquisition of image data of the examination subject is initiated by the x-ray imaging system at a plurality of points along the non-planar image data acquisition path. A 3-dimensional image is constructed from the acquired image data such that any metal artifacts introduced by radio-opaque objects within the examination subject are minimized. The 3-dimensional image is displayed.
摘要翻译：一种方法和系统提供检查对象的医学图像处理和三维图像构造。能够使用户能够相对于用于保持检查对象的检查对象支架选择性地定向具有可变的3维获取轴的x射线成像系统。响应于用户指令，针对可变3维获取轴线的x射线成像系统设置非平面图像数据获取路径。检查对象的图像数据的采集由X射线成像系统沿着非平面图像数据获取路径的多个点发起。从所获取的图像数据构建3维图像，使得由检查对象内的不透射线物体引入的任何金属伪影最小化。显示三维图像。

4. 发明申请

US20100053209A1 System for Processing Medical Image data to Provide Vascular Function Information 审中-公开
标题翻译：用于处理医学图像数据以提供血管功能信息的系统
公开(公告)号：US20100053209A1
公开(公告)日：2010-03-04
申请号：US12550719
申请日：2009-08-31
申请人： John Christopher Rauch , John Baumgart
发明人： John Christopher Rauch , John Baumgart
IPC分类号： G09G5/00 , A61B6/00
CPC分类号： A61B6/504 , A61B6/4441 , A61B6/507 , G06T5/50 , G06T15/08 , G06T19/20 , G06T2210/41 , G06T2219/2012
摘要： A system creates a visually (e.g., color) coded 3D image that depicts 3D vascular function information including transit time of blood flow through the anatomy. A system combines 3D medical image data with vessel blood flow information. The system uses at least one repository for storing, 3D image data representing a 3D imaging volume including vessels, in the presence of a contrast agent and 2D image data representing a 2D X-ray image through the imaging volume in the presence of a contrast agent. An image data processor uses the 3D image data and the 2D image data in deriving blood flow related information for the vessels. A display processor provides data representing a composite single displayed image including a vessel structure provided by the 3D image data and the derived blood flow related information.
摘要翻译：系统创建描绘3D血管功能信息的视觉（例如，颜色）编码的3D图像，其包括通过解剖结构的血流的传播时间。系统将3D医学图像数据与血管血流信息相结合。在存在造影剂的情况下，系统使用至少一个存储库来存储表示包含血管的3D成像体积的3D图像数据，并且在造影剂存在下通过成像体积表示2D X射线图像的2D图像数据。图像数据处理器使用3D图像数据和2D图像数据来导出血管相关信息。显示处理器提供表示包括由3D图像数据提供的血管结构和衍生的血流相关信息的复合单显示图像的数据。

5. 发明授权

US10064595B2 System for coregistration of optical coherence tomography and angiographic X-ray image data 有权
公开(公告)号：US10064595B2
公开(公告)日：2018-09-04
申请号：US13856510
申请日：2013-04-04
申请人： John Baumgart , Olivier Ecabert , John Christopher Rauch
发明人： John Baumgart , Olivier Ecabert , John Christopher Rauch
IPC分类号： A61B5/05 , A61B6/00 , A61B5/00 , A61B6/12 , A61M5/00 , A61B5/0452
摘要： A system comprises a catheter including a lens, for acquiring optical coherence tomography images within the vessel of interest as the catheter is being retracted from the vessel in the presence of contrast agent. An X-ray imaging system interface receives a first set of X-ray images of an anatomical region including the vessel of interest containing the catheter. The first set of X-ray images are acquired at points corresponding to the particular points within a heart cycle, while the catheter is stationary in the vessel, in response to a heart electrical activity representative signal and in the absence of contrast agent. An image data processor associates the received X-ray images and corresponding optical coherence tomography image data derived at corresponding time points within respective acquisition heart cycles.

6. 发明授权

US08731262B2 Medical image and vessel characteristic data processing system 有权
标题翻译：医学影像与血管特征数据处理系统
公开(公告)号：US08731262B2
公开(公告)日：2014-05-20
申请号：US13026417
申请日：2011-02-14
申请人： John Christopher Rauch
发明人： John Christopher Rauch
IPC分类号： G06K9/00
CPC分类号： G06T7/254 , A61B6/504 , G06T2207/10016 , G06T2207/10116 , G06T2207/20224 , G06T2207/30101
摘要： An image data processing system automatically indicates an image of a digitally subtracted Angiography (DSA) image sequence is associated with at least one of, arterial, venous, or capillary phases of blood flow. The system includes an interface for acquiring data representing a DSA sequence of digitally subtracted images enhancing vessel structure. An image data processor automatically indicates an image of the DSA sequence is associated with at least one of, arterial, venous, or capillary phases of blood flow by determining individual minimum luminance intensity level values of individual images of the DSA sequence and using the determined individual minimum luminance intensity level values in identifying images of the DSA sequence are associated with at least one of, arterial, venous, or capillary phases of blood flow. An output processor automatically assigns an attribute to image data to identify vessel phase in response to the identifying images of the DSA sequence.
摘要翻译：图像数据处理系统自动指示数字减影血管造影（DSA）图像序列的图像与血流的动脉，静脉或毛细血管相中的至少一个相关联。该系统包括用于获取表示增强血管结构的数字减影图像的DSA序列的数据的接口。图像数据处理器通过确定DSA序列的各个图像的个别最小亮度强度水平值并使用所确定的个体，自动地指示DSA序列的图像与血流的动脉，静脉或毛细血管相中的至少一个相关联识别DSA序列的图像中的最小亮度强度值与血流的动脉，静脉或毛细血管相中的至少一个相关联。输出处理器自动将属性分配给图像数据，以响应于DSA序列的识别图像来识别血管相。

7. 发明申请

US20110299749A1 Medical Image and Vessel Characteristic Data Processing System 有权
标题翻译：医学图像与血管特征数据处理系统
公开(公告)号：US20110299749A1
公开(公告)日：2011-12-08
申请号：US13026417
申请日：2011-02-14
申请人： John Christopher Rauch
发明人： John Christopher Rauch
IPC分类号： G06K9/00
CPC分类号： G06T7/254 , A61B6/504 , G06T2207/10016 , G06T2207/10116 , G06T2207/20224 , G06T2207/30101
摘要： An image data processing system automatically indicates an image of a digitally subtracted Angiography (DSA) image sequence is associated with at least one of, arterial, venous, or capillary phases of blood flow. The system includes an interface for acquiring data representing a DSA sequence of digitally subtracted images enhancing vessel structure. An image data processor automatically indicates an image of the DSA sequence is associated with at least one of, arterial, venous, or capillary phases of blood flow by determining individual minimum luminance intensity level values of individual images of the DSA sequence and using the determined individual minimum luminance intensity level values in identifying images of the DSA sequence are associated with at least one of, arterial, venous, or capillary phases of blood flow. An output processor automatically assigns an attribute to image data to identify vessel phase in response to the identifying images of the DSA sequence,
摘要翻译：图像数据处理系统自动指示数字减影血管造影（DSA）图像序列的图像与血流的动脉，静脉或毛细血管相中的至少一个相关联。该系统包括用于获取表示增强血管结构的数字减影图像的DSA序列的数据的接口。图像数据处理器通过确定DSA序列的各个图像的个别最小亮度强度水平值并使用所确定的个体，自动地指示DSA序列的图像与血流的动脉，静脉或毛细血管相中的至少一个相关联识别DSA序列的图像中的最小亮度强度值与血流的动脉，静脉或毛细血管相中的至少一个相关联。输出处理器自动地将属性分配给图像数据以响应于DSA序列的识别图像来识别血管相位，

8. 发明申请

US20130281832A1 System for Coregistration of Optical Coherence Tomography and Angiographic X-ray Image Data 审中-公开
标题翻译：光学相干断层扫描和血管造影X射线图像数据的核心系统
公开(公告)号：US20130281832A1
公开(公告)日：2013-10-24
申请号：US13856510
申请日：2013-04-04
申请人： John Baumgart , Olivier Ecabert , John Christopher Rauch
发明人： John Baumgart , Olivier Ecabert , John Christopher Rauch
IPC分类号： A61B6/00 , A61M5/00 , A61B6/12 , A61B5/00
CPC分类号： A61B6/5247 , A61B5/0035 , A61B5/0066 , A61B5/0084 , A61B5/0452 , A61B5/4839 , A61B5/7289 , A61B6/12 , A61B6/4417 , A61B6/4441 , A61B6/484 , A61B6/503 , A61B6/504 , A61B6/541 , A61M5/007
摘要： A system comprises a catheter including a lens, for acquiring optical coherence tomography images within the vessel of interest as the catheter is being retracted from the vessel in the presence of contrast agent. An X-ray imaging system interface receives a first set of X-ray images of an anatomical region including the vessel of interest containing the catheter. The first set of X-ray images are acquired at points corresponding to the particular points within a heart cycle, while the catheter is stationary in the vessel, in response to a heart electrical activity representative signal and in the absence of contrast agent. An image data processor associates the received X-ray images and corresponding optical coherence tomography image data derived at corresponding time points within respective acquisition heart cycles.
摘要翻译：系统包括导管，其包括透镜，用于在存在造影剂的情况下导管从血管中缩回，用于获取感兴趣血管内的光学相干断层图像。 X射线成像系统接口接收包括包含导管的感兴趣血管的解剖区域的第一组X射线图像。响应于心脏电活动代表性信号并且在没有造影剂的情况下，导管在血管中静止，在与心脏周期内的特定点对应的点处获取第一组X射线图像。图像数据处理器将接收到的X射线图像和在相应的采集心脏周期内的相应时间点导出的对应的光学相干断层摄影图像数据相关联。

9. 发明申请

US20130094734A1 System for Comparison of Medical Images 有权
标题翻译：医学图像比较系统
公开(公告)号：US20130094734A1
公开(公告)日：2013-04-18
申请号：US13273439
申请日：2011-10-14
申请人： John Christopher Rauch , John Baumgart
发明人： John Christopher Rauch , John Baumgart
IPC分类号： G06K9/00
CPC分类号： G06T7/38 , G06T2207/10116 , G06T2207/30101
摘要： A system automatically processes different medical image sequences facilitating comparison of the sequences in adjacent respective display areas. An image data processor, identifies first and second mask images of first and second image sequences respectively as images preceding introduction of contrast agent and determines a translational shift between the first and second mask images. The image data processor transforms data representing individual images of at least one of the first image sequence and the second image sequence in response to the determined translational shift to reduce mis-alignment of the individual images of the first image sequence relative to the individual images of the second image sequence. A display presents first and second image sequences corrected for mis-alignment, in substantially adjacent display areas to facilitate user comparison.
摘要翻译：系统自动处理不同的医学图像序列，便于在相邻的各个显示区域中对序列进行比较。图像数据处理器分别将第一和第二图像序列的第一和第二掩模图像分别识别为引入造影剂之前的图像，并确定第一和第二掩模图像之间的平移位移。图像数据处理器响应于所确定的平移移位来变换表示第一图像序列和第二图像序列中的至少一个的各个图像的数据，以减少第一图像序列的各个图像相对于各个图像的不对准第二个图像序列。显示器在基本上相邻的显示区域中呈现针对不对准校正的第一和第二图像序列，以便于用户比较。

10. 发明申请

US20120201439A1 Digital Subtraction Angiography (DSA) Motion Compensated Imaging System 有权
标题翻译：数字减影血管造影（DSA）运动补偿成像系统
公开(公告)号：US20120201439A1
公开(公告)日：2012-08-09
申请号：US13252238
申请日：2011-10-04
申请人： John Christopher Rauch , John Baumgart
发明人： John Christopher Rauch , John Baumgart
IPC分类号： G06K9/00
CPC分类号： G06T7/20 , G06T2207/20224 , G06T2207/30101
摘要： A motion compensated digitally subtracted Angiography (DSA) image processing system includes an interface for acquiring a sequence of images of patient vessels both prior to and following introduction of contrast agent into the vessels. An image data processor automatically, (a) determines a first shift vector for a first image of the sequence for compensating for shift between the first image and a first reference image of the sequence, (b) applies the determined first shift vector to the first image of the sequence to produce a shifted image, (c) subtracts the first reference image from the shifted image to produce a subtracted image enhancing vessel structure, (d) determines a second shift vector for compensating for shift between the subtracted image and a second reference image and (e) shifts content of the subtracted image relative to the second reference image in response to the second shift vector, to provide a shifted subtracted image enhancing and aligning vessel structure.
摘要翻译：运动补偿数字减影血管造影（DSA）图像处理系统包括用于在将造影剂引入血管之前和之后获取患者血管的图像序列的界面。图像数据处理器自动地（a）确定用于补偿第一图像与序列的第一参考图像之间的偏移的序列的第一图像的第一移位矢量，（b）将确定的第一移位向量应用于第一图像用于产生移位图像的图像的图像，（c）从移位图像中减去第一参考图像以产生减影图像增强容器结构，（d）确定用于补偿相减图像与第二参考图像之间的偏移的第二移位矢量参考图像和（e）响应于第二移位矢量移动相减相对于第二参考图像的内容，以提供偏移减去的图像增强和对准血管结构。

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