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1. 发明授权

US08895733B2 Triazine-oxadiazoles 有权
标题翻译：三嗪 - 恶二唑
公开(公告)号：US08895733B2
公开(公告)日：2014-11-25
申请号：US14054221
申请日：2013-10-15
申请人： Oliver Barker , Jonathan Mark Bentley , Mark G. Bock , Thomas Cain , Praful Chovatia , Jennifer Ruth Dod , Florence Eustache , Laura Gleave , Jonathan Hargrave , Alexander Heifetz , Richard Law , Ali Raoof , David Willows
发明人： Oliver Barker , Jonathan Mark Bentley , Mark G. Bock , Thomas Cain , Praful Chovatia , Jennifer Ruth Dod , Florence Eustache , Laura Gleave , Jonathan Hargrave , Alexander Heifetz , Richard Law , Ali Raoof , David Willows
IPC分类号： C07D413/04 , C07D413/14 , A61K31/53 , A61P29/00 , A61K45/06 , C07D498/08 , C07D491/10 , C07D451/02 , C07D491/107 , C07D417/14 , C07D487/04
CPC分类号： C07D413/14 , A61K31/53 , A61K31/5377 , A61K31/5386 , A61K45/06 , C07D413/04 , C07D417/14 , C07D451/02 , C07D487/04 , C07D491/10 , C07D491/107 , C07D498/08
摘要： The invention relates to new derivatives of formula (I), wherein the substituents are as defined in the specification; to processes for the preparation of such derivatives; pharmaceutical compositions comprising such derivatives; such derivatives as a medicament; such derivatives for the treatment of chronic pain.
摘要翻译：本发明涉及式（I）的新衍生物，其中取代基如说明书中所定义; 制备此类衍生物的方法; 包含这些衍生物的药物组合物; 这种衍生物作为药物; 用于治疗慢性疼痛的衍生物。

2. 发明授权

US08882798B2 Endoscopic tools for the removal of balloon-like intragastric devices 有权
标题翻译：用于去除气球样胃内装置的内窥镜工具
公开(公告)号：US08882798B2
公开(公告)日：2014-11-11
申请号：US13372171
申请日：2012-02-13
申请人： Justin J. Schwab , Tiago Bertolote , Zachary P. Dominguez , Mitchell H. Babkes , Richard Law
发明人： Justin J. Schwab , Tiago Bertolote , Zachary P. Dominguez , Mitchell H. Babkes , Richard Law
IPC分类号： A61B17/50
CPC分类号： A61F5/0089 , A61B17/50 , A61B2017/00349 , A61B2017/00818 , A61B2017/22035 , A61B2017/305 , A61F5/003 , A61F5/0036
摘要： A mechanism for removing a fluid-filled object such as an intragastric balloon from a patient. The apparatus includes a delivery tube having a lumen and a retrieval tool able to slide within the lumen that can both puncture and grasp the intragastric balloon. The retrieval tool may have sharpened graspers with either a sharp tip and/or knife-like edges. Alternatively, the delivery tube itself may have sharpened cutting blades that deploy outward to puncture the intragastric balloon. One embodiment utilizes a suction cup tip on the delivery sheath and a sharpened puncture rod that extends past the distal tip of the lumen, for rapid deflation of a balloon. Various embodiments hasten the deflation process and simplify the manipulation required by the surgeon.
摘要翻译：用于从患者去除流体填充物体例如胃内气球的机构。该装置包括具有内腔的输送管和能够在内腔内滑动的取出工具，其能够刺穿并抓住胃内气囊。回收工具可能具有锋利的尖端和/或刀状边缘的锋利的抓紧器。或者，输送管本身可以具有向外展开以刺穿胃内气囊的锋利的切割刀片。一个实施例使用输送护套上的吸盘尖端和延伸穿过内腔的远端的锐化穿刺杆，用于气囊的快速放气。各种实施例加速了放气过程并简化了外科医生所需的操作。

3. 发明申请

US20070162153A1 Prosthetic sock providing graduated thickness and tibial crest load reduction for an amputee limb remnant 审中-公开
标题翻译：假肢袜子为截肢肢残留提供刻度厚度和胫骨顶峰负荷
公开(公告)号：US20070162153A1
公开(公告)日：2007-07-12
申请号：US11326733
申请日：2006-01-07
申请人： Leslie Barnes , Richard Law
发明人： Leslie Barnes , Richard Law
IPC分类号： A61F2/78
CPC分类号： A61F2/78 , A61F2/5046 , A61F2/80 , A61F2002/5055 , A61F2002/5083
摘要： A prosthetic sock configured to accommodate a transtibial amputee's residuum volume reductions which occur over time and are greater distally than proximally. It is also applicable to other amputee limbs and other levels of amputation of the leg and arm. The sock provides better compensation for the increased distal volume shrinkage and it reduces discomfort from localized loading on the stump by providing a knitted thickness that is greater distally and then tapers to a lesser proximal knitted thickness. A transtibial amputee's residuum is more sensitive to pressure over the tibial bone and this sock also provides a reduced local thickness over the tibial crest area which decreases the localized pressure in this region. Since the sock accommodates the loss of tissue volume in the distal end of the prosthetic socket, it thereby provides improved stump stability inside the prosthetic socket and improves amputee control and stability in walking.
摘要翻译：假体袜被配置为适应经胫骨截肢者的残余体积减小，其随时间发生并且比近端更远。它也适用于其他截肢肢体和其他肢体和手臂的截肢水平。袜子为增加的远端体积收缩提供更好的补偿，并且通过提供更大的远端的针织厚度并随后逐渐变细到较小的近端针织厚度来减小残端上局部加载的不适。经胫骨截肢者的残留物对胫骨骨骼的压力更敏感，并且该袜子还提供了比胫骨顶部区域更薄的局部厚度，这降低了该区域的局部压力。由于袜子容纳了假肢插座的远端中的组织体积的损失，因此其在假体插座内部提供了改进的残端稳定性，并且改善了截肢者的控制和步行的稳定性。

4. 发明申请

US20130211440A1 ENDOSCOPIC TOOLS FOR THE REMOVAL OF BALLOON-LIKE INTRAGASTRIC DEVICES 有权
标题翻译：用于去除气球式内脏装置的内窥镜工具
公开(公告)号：US20130211440A1
公开(公告)日：2013-08-15
申请号：US13372171
申请日：2012-02-13
申请人： Justin J. Schwab , Tiago Bertolote , Zachary P. Dominguez , Mitchell H. Babkes , Richard Law
发明人： Justin J. Schwab , Tiago Bertolote , Zachary P. Dominguez , Mitchell H. Babkes , Richard Law
IPC分类号： A61M29/02
CPC分类号： A61F5/0089 , A61B17/50 , A61B2017/00349 , A61B2017/00818 , A61B2017/22035 , A61B2017/305 , A61F5/003 , A61F5/0036
摘要： A mechanism for removing a fluid-filled object such as an intragastric balloon from a patient. The apparatus includes a delivery tube having a lumen and a retrieval tool able to slide within the lumen that can both puncture and grasp the intragastric balloon. The retrieval tool may have sharpened graspers with either a sharp tip and/or knife-like edges. Alternatively, the delivery tube itself may have sharpened cutting blades that deploy outward to puncture the intragastric balloon. One embodiment utilizes a suction cup tip on the delivery sheath and a sharpened puncture rod that extends past the distal tip of the lumen, for rapid deflation of a balloon. Various embodiments hasten the deflation process and simplify the manipulation required by the surgeon.
摘要翻译：用于从患者去除流体填充物体例如胃内气球的机构。该装置包括具有内腔的输送管和能够在内腔内滑动的取出工具，其能够刺穿并抓住胃内气囊。回收工具可能具有锋利的尖端和/或刀状边缘的锋利的抓紧器。或者，输送管本身可以具有向外展开以刺穿胃内气囊的锋利的切割刀片。一个实施例使用输送护套上的吸盘尖端和延伸穿过内腔的远端的锐化穿刺杆，用于气囊的快速放气。各种实施例加速了放气过程并简化了外科医生所需的操作。

5. 发明申请

US20050076628A1 Ground supported motorized sickle bar mower for use on sloping terrain 审中-公开
标题翻译：地面支持电动镰刀式割草机，用于倾斜的地形
公开(公告)号：US20050076628A1
公开(公告)日：2005-04-14
申请号：US10682564
申请日：2003-10-10
申请人： Richard Law
发明人： Richard Law
IPC分类号： A01D34/08 , A01D34/86 , A01D34/13
CPC分类号： A01D34/08 , A01D34/86
摘要： A motorized mower provides an elongate frame journaling two elongately spaced co-planar wheels for ground support and supporting a rearwardly and upwardly extending handle for manipulation. The frame carries a powering structure having a motor carried on a depending powering column carried for adjustable vertical positioning by the frame and communicating with a lowermost transmission structure. The transmission structure carries a reciprocating double-sided sickle extending laterally from the frame for adjustable pivotal positioning in a laterally extending vertical plane. The frame is of releasable compound nature to allow folding of the handle and sickle bar for compaction during periods of non-use.
摘要翻译：电动割草机提供了一个细长的框架，用于延伸两个长度间隔的共面轮，用于地面支撑并支撑向后和向上延伸的手柄用于操纵。该框架具有电动结构，其具有承载在借助框架进行可调节的垂直定位并且与最下面的传输结构连通的依赖供电柱上的电动机。传动结构带有一个从框架横向延伸的往复式双面镰刀，用于在横向延伸的垂直平面内进行可调节的枢转定位。框架具有可释放的复合性质，以允许在不使用期间折叠手柄和镰刀条以进行压实。

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