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    • 1. 发明申请
    • ELECTROCHEMICAL SENSING METHOD
    • 电化学传感方法
    • WO2006000829A3
    • 2006-03-23
    • PCT/GB2005002558
    • 2005-06-29
    • OXFORD BIOSENSORS LTDHYLAND MARKBROUGHALL JOHN MORTONBUTLER RONALD NEIL
    • HYLAND MARKBROUGHALL JOHN MORTONBUTLER RONALD NEIL
    • G01N27/30C12Q1/00
    • C12Q1/001G01N27/3272Y10T29/49108
    • A method of confining an electroactive substance (7) within an electrochemical cell in the form of a receptacle, said method comprising: (a) providing an electrochemical cell in the form of a receptacle, the receptacle having a first open part (3) to allow entry of a sample into the receptacle, and a second open part to allow escape of air displaced by the entering sample, the electrochemical cell having a working electrode (5) 1 and a counter electrode (6); (b) providing an electroactive substance (7), which substance is contained within the receptacle; (c) providing a permeable or semi-permeable membrane (4), comprising one or more layers, covering the first open part of the receptacle; and (d) inserting the sample into the receptacle through the membrane, such that (1) the electroactive substance and (2) the sample, are in contact with each other and with.-said working electrode; wherein the electroactive is confined within the receptacle during step (d). Preferably, the method additionally involves electrochemically testing a sample, by applying a voltage across the cell and measuring the resulting electrochemical response.
    • 将电活性物质(7)限制在容器形式的电化学电池内的方法,所述方法包括:(a)提供呈容器形式的电化学电池,所述容器具有第一开口部分(3)至 允许样品进入容器,以及第二开放部分,以允许由进入的样品排出的空气逸出,所述电化学电池具有工作电极(5)1和对电极(6); (b)提供电活性物质(7),该物质包含在容器内; (c)提供覆盖容器的第一开放部分的可渗透或半透膜(4),包括一层或多层; 和(d)通过膜将样品插入容器中,使得(1)电活性物质和(2)样品彼此接触并与所述工作电极接触; 其中在步骤(d)期间电活性被限制在容器内。 优选地,该方法还涉及通过在电池上施加电压并测量所得到的电化学响应来电化学测试样品。
    • 4. 发明申请
    • ELECTRODE PRECONDITIONING
    • 电极预处理
    • WO2006000827A3
    • 2006-03-02
    • PCT/GB2005002551
    • 2005-06-29
    • OXFORD BIOSENSORS LTDHYLAND MARKBOND ALAN MAXWELL
    • HYLAND MARKBOND ALAN MAXWELL
    • G01N27/30G01N27/49
    • G01N27/4045G01N27/308
    • An electrochemical sensing method comprising: (a) providing an electrochemical cell having a working electrode and a pseudo reference electrode; (b) providing a sample comprising a metal, the sample being in contact with the working electrode and the metal being capable of being oxidised or reduced at the working electrode when the metal is bound to the working electrode; (c) preconditioning the working electrode by (i) applying a time varying preconditioning potential between the working and pseudo reference electrodes; and/or (ii) baking the working electrode; and/or (iii) air-ageing the working electrode; and (d) applying a measuring potential between the working and pseudo reference electrodes and, during application of said measuring potential, measuring the current generated by oxidation/reduction of the metal at the working electrode.
    • 一种电化学传感方法,包括:(a)提供具有工作电极和伪参考电极的电化学电池; (b)提供包含金属的样品,所述样品与所述工作电极接触,并且当所述金属结合至所述工作电极时,所述金属能够在所述工作电极处被氧化或还原; (c)通过(i)在工作参考电极和伪参考电极之间施加时变预处理电位来预处理工作电极; 和/或(ii)烘烤工作电极; 和/或(iii)使工作电极空气老化; (d)在工作参考电极和伪参考电极之间施加测量电位,并且在施加所述测量电位的过程中,测量由工作电极处的金属的氧化/还原产生的电流。