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1. 发明公开

EP3043728A1 STAGED, BILATERALLY EXPANDABLE TRIAL 审中-公开
标题翻译： PROGRESSIVE双面可膨胀试用
公开(公告)号：EP3043728A1
公开(公告)日：2016-07-20
申请号：EP14842880.8
申请日：2014-09-06
申请人： Ouroboros Medical Inc. , To, John , Rao, Praveen, Gopal
发明人： TO, John , RAO, Praveen, Gopal
IPC分类号： A61B17/70 , A61B17/66
CPC分类号： A61F2/4684 , A61B17/025 , A61B2017/0256 , A61F2/442 , A61F2/4425 , A61F2/4455 , A61F2/4611 , A61F2002/30018 , A61F2002/30154 , A61F2002/30163 , A61F2002/30266 , A61F2002/30545 , A61F2002/3055 , A61F2002/30556 , A61F2002/30563 , A61F2002/30565 , A61F2002/30579
摘要： Systems and methods for distracting an intervertebral disc space are provided. The systems use a staged, bilaterally expandable trial. The systems and methods of distracting an intervertebral space are provided in a manner that addresses the problem of subsidence. The method includes inserting the trial into the intervertebral space in a collapsed state and, once inserted, the trial is then used for distracting the intervertebral space using an expansion that includes a first stage and a second stage. The first stage includes expanding the trial laterally toward the peripheral zones of the top vertebral plate and the bottom vertebral plate, and the second stage includes expanding the trial vertically to distract the intervertebral space.

2. 发明申请

WO2015035269A1 STAGED, BILATERALLY EXPANDABLE TRIAL 审中-公开
标题翻译：标准，双重可扩展的尝试
公开(公告)号：WO2015035269A1
公开(公告)日：2015-03-12
申请号：PCT/US2014/054437
申请日：2014-09-06
申请人： OUROBOROS MEDICAL, INC. , TO, John , RAO, Praveen, Gopal
发明人： TO, John , RAO, Praveen, Gopal
IPC分类号： A61B17/70 , A61B17/66
CPC分类号： A61F2/4684 , A61B17/025 , A61B2017/0256 , A61F2/442 , A61F2/4425 , A61F2/4455 , A61F2/4611 , A61F2002/30018 , A61F2002/30154 , A61F2002/30163 , A61F2002/30266 , A61F2002/30545 , A61F2002/3055 , A61F2002/30556 , A61F2002/30563 , A61F2002/30565 , A61F2002/30579
摘要： Systems and methods for distracting an intervertebral disc space are provided. The systems use a staged, bilaterally expandable trial. The systems and methods of distracting an intervertebral space are provided in a manner that addresses the problem of subsidence. The method includes inserting the trial into the intervertebral space in a collapsed state and, once inserted, the trial is then used for distracting the intervertebral space using an expansion that includes a first stage and a second stage. The first stage includes expanding the trial laterally toward the peripheral zones of the top vertebral plate and the bottom vertebral plate, and the second stage includes expanding the trial vertically to distract the intervertebral space.
摘要翻译：提供了分散椎间盘空间的系统和方法。系统使用分阶段的双边扩张试验。以解决沉降问题的方式提供分散脊椎间隙的系统和方法。该方法包括将试验插入椎间隙中，并且一旦插入，则试验然后用于使用包括第一阶段和第二阶段的扩张来分散脊椎间隙。第一阶段包括将试验横向扩展到顶部椎板和底椎板的周边区域，第二阶段包括垂直扩张试验以分散椎间空间。

3. 发明申请

WO2013081691A1 SAFE CUTTING HEADS AND SYSTEMS FOR FAST REMOVAL OF A TARGET TISSUE 审中-公开
标题翻译：安全切割头和系统快速去除目标组织
公开(公告)号：WO2013081691A1
公开(公告)日：2013-06-06
申请号：PCT/US2012/051952
申请日：2012-08-22
申请人： OUROBOROS MEDICAL, INC. , TO, John
发明人： TO, John
IPC分类号： A61B17/3205 , A61B17/3209 , A61B17/34 , A61B17/70
CPC分类号： A61B17/3205 , A61B17/320016 , A61B17/32002 , A61B2017/00261 , A61B2017/00738 , A61B2017/320064 , A61B2090/08021 , A61B2217/002 , A61F2/44 , A61F2002/444
摘要： A safe and efficient cutting heads for removing a target tissue from a subject during a surgical procedure are provided, the cutting heads composing a part of systems that address several problems, including clogging of state-of-the-art systems during removal of such tissue, for example. The target tissue can include any tissue that is accessible through a small surgical opening, for example, a joint tissue such as a meniscus or an intervertebral tissue, such as a nucleus pulposus. The devices can be referred to as orthopedic tissue removal devices having cutting heads associated with vacuum systems, making the systems useful in several procedures, including X-LIF (lateral approach to an intervertebral fusions) procedures, T-LIF (transforaminal approach to intervertebral fusions) procedures, P-LIF (posterior approach to intervertebral fusions), and a percutaneous, transforaminal approach (Kambin triangle access).
摘要翻译：提供了一种用于在外科手术过程中从被检体去除目标组织的安全且有效的切割头，所述切割头构成解决几个问题的系统的一部分，包括在移除这样的组织期间堵塞最先进的系统，例如。目标组织可包括通过小的外科手术开口可接近的任何组织，例如关节组织，例如弯月面或椎间组织，例如髓核。这些装置可以称为具有与真空系统相关联的切割头的整形外科组织去除装置，使得该系统在若干程序中有用，包括X-LIF（侧椎间融合术）方法，T-LIF（经椎间融合椎间融合术）程序，P-LIF（椎间融合的后路）和经皮，经椎间孔的方法（Kambin三角形通路）。

4. 发明申请

WO2014093136A1 A BONE GRAFT DISTRIBUTION SYSTEM 审中-公开
标题翻译：骨折分配系统
公开(公告)号：WO2014093136A1
公开(公告)日：2014-06-19
申请号：PCT/US2013/073435
申请日：2013-12-05
申请人： OUROBOROS MEDICAL, INC , TO, John , FLYNN, John, J. , BIRKMEYER, Paul, J.
发明人： TO, John , FLYNN, John, J. , BIRKMEYER, Paul, J.
IPC分类号： A61F2/44 , A61B17/70 , A61F2/28
CPC分类号： A61F2/447 , A61F2/30965 , A61F2/441 , A61F2/442 , A61F2/4611 , A61F2/4684 , A61F2002/2817 , A61F2002/2835 , A61F2002/30019 , A61F2002/30556 , A61F2002/30579 , A61F2002/30581 , A61F2002/30598 , A61F2002/30777 , A61F2002/30779 , A61F2002/30785 , A61F2002/4435 , A61F2002/444 , A61F2002/4475 , A61F2310/00011 , A61F2310/00023 , A61F2310/00029 , A61F2310/00047 , A61F2310/00053 , A61F2310/00071 , A61F2310/00179 , A61F2310/00293
摘要： A system for distributing bone graft material in an intervertebral disc space is provided having a central beam having a proximal portion having an end, a grafting portion having a top and a bottom, a distal portion having a end, a central beam axis, a graft distribution channel having an entry port at the end of the proximal portion, a top exit port at the top of the grafting portion, and a bottom exit port at the bottom of the grafting portion. These systems can also include a laterovertically-expanding frame operable for a reversible collapse from an expanded state into a collapsed state. The expanded state, for example, can be configured to have an open graft distribution window that at least substantially closes upon the reversible collapse.
摘要翻译：提供了一种用于在椎间盘空间中分配骨移植材料的系统，其具有中心束，所述中央束具有近端部分，其具有端部，接合部分具有顶部和底部，远侧部分具有端部，中心束轴线，移植物分配通道在近端部分的端部具有入口，在接合部分的顶部具有顶部出口，在接合部分的底部具有底部出口。这些系统还可以包括可以从展开状态到折叠状态的可逆崩溃的可稍后膨胀的框架。膨胀状态例如可被配置为具有在可逆崩溃时至少基本上闭合的开放的移植物分布窗口。

5. 发明公开

EP3021768A1 AN ANTI-CLOGGING DEVICE FOR A VACUUM-ASSISTED, TISSUE REMOVAL SYSTEM 有权转让
标题翻译：堵塞抑制装置的真空辅助组织切除系统
公开(公告)号：EP3021768A1
公开(公告)日：2016-05-25
申请号：EP14826656.2
申请日：2014-07-15
申请人： Ouroboros Medical, Inc. , To, John , Osorio, Fred , Zaretzka, Gary, Daniel
发明人： TO, John , OSORIO, Fred , ZARETZKA, Gary, Daniel
IPC分类号： A61B17/3205 , A61B17/22 , A61M1/00 , A61B17/16
CPC分类号： A61B17/320016 , A61B17/1671 , A61B17/3205 , A61B2017/00261 , A61B2090/08021 , A61B2217/005
摘要： An anti-clogging device for a vacuum-assisted tissue removal system is provided. The device includes a tissue-separation chamber in a close proximity to (i) a cutting head operated by a physician and (ii) the physician for a filling and emptying by the physician during a tissue removal procedure, the cutting head and the tissue separation chamber in an operable communications with the suction assembly. The tissue separation chamber has an entry port in an operable communication with the cutting head for the entry of an excised tissue into the chamber, the excised tissue having a solid component and a liquid component; a baffle to separate the liquid component from the solid component; and, an exit port for the exit of liquid component out of the chamber. The tissue can include any tissue accessible through a small surgical opening, such as a nucleus pulposus tissue removed during a discectomy procedure.

6. 发明申请

WO2016118608A1 STABILIZED INTERVERTEBRAL SCAFFOLDING SYSTEMS 审中-公开
标题翻译：稳定的椎间融合系统
公开(公告)号：WO2016118608A1
公开(公告)日：2016-07-28
申请号：PCT/US2016/014100
申请日：2016-01-20
申请人： OUROBOROS MEDICAL, INC. , TO, John , FLYNN, John, J.
发明人： TO, John , FLYNN, John, J.
IPC分类号： A61F2/44 , A61F2/28
CPC分类号： A61F2/447 , A61F2/442 , A61F2/4455 , A61F2/4611 , A61F2002/2835 , A61F2002/30471 , A61F2002/30476 , A61F2002/30545 , A61F2002/30556 , A61F2002/30579 , A61F2002/4677
摘要： An intervertebral scaffolding system is provided having a central beam having a proximal portion having an end, a grafting portion having a top and a bottom, a distal portion having a end, a central beam axis, a graft distribution channel having an entry port at the end of the proximal portion, a top exit port at the top of the grafting portion, and a bottom exit port at the bottom of the grafting portion. These systems can also include a laterovertically-expanding frame operable for a reversible collapse from an expanded state into a collapsed state. The expanded state, for example, can be configured to have an open graft distribution window that at least substantially closes upon the reversible collapse.
摘要翻译：提供了一种椎间骨架系统，其具有中心梁，所述中心梁具有近端部分，所述近端部分具有端部，接合部分具有顶部和底部，远端部分具有端部，中心束轴线，移植物分配通道，近端部分的端部，接合部分顶部的顶部出口以及接合部分底部的底部出口。这些系统还可以包括可以从展开的状态到折叠状态的可逆崩溃的可反复膨胀的框架。膨胀状态例如可被配置为具有在可逆崩溃时至少基本上闭合的开放移植物分布窗口。

7. 发明申请

WO2015009763A8 AN ANTI-CLOGGING DEVICE FOR A VACUUM-ASSISTED, TISSUE REMOVAL SYSTEM 审中-公开
公开(公告)号：WO2015009763A8
公开(公告)日：2015-01-22
申请号：PCT/US2014/046762
申请日：2014-07-15
申请人： OUROBOROS MEDICAL, INC. , TO, John , OSORIO, Fred , ZARETZKA, Gary, Daniel
发明人： TO, John , OSORIO, Fred , ZARETZKA, Gary, Daniel
IPC分类号： A61B17/3205 , A61B17/22 , A61M1/00 , A61B17/16
摘要： An anti-clogging device for a vacuum-assisted tissue removal system is provided. The device includes a tissue-separation chamber in a close proximity to (i) a cutting head operated by a physician and (ii) the physician for a filling and emptying by the physician during a tissue removal procedure, the cutting head and the tissue separation chamber in an operable communications with the suction assembly. The tissue separation chamber has an entry port in an operable communication with the cutting head for the entry of an excised tissue into the chamber, the excised tissue having a solid component and a liquid component; a baffle to separate the liquid component from the solid component; and, an exit port for the exit of liquid component out of the chamber. The tissue can include any tissue accessible through a small surgical opening, such as a nucleus pulposus tissue removed during a discectomy procedure.

8. 发明申请

WO2014022443A1 A MINIMALLY-INVASIVE, LATEROVERTICALLY EXPANDING, INTERVERTEBRAL DISC SCAFFOLDING 审中-公开
标题翻译：最小的入场，离散扩展，椎间盘间隙
公开(公告)号：WO2014022443A1
公开(公告)日：2014-02-06
申请号：PCT/US2013/052799
申请日：2013-07-30
申请人： OUROBOROS MEDICAL, INC. , TO, John , FLYNN, John J. , BIRKMEYER, Paul J.
发明人： TO, John , FLYNN, John J. , BIRKMEYER, Paul J.
IPC分类号： A61L27/56 , A61F2/28 , A61F2/44
CPC分类号： A61F2/4455 , A61F2/4601 , A61F2/4684 , A61F2002/2835 , A61F2002/30471 , A61F2002/30556 , A61F2002/30579
摘要： A laterovertically expandable scaffolding is provided for supporting an intervertebral disc space using a minimally invasive procedure. The scaffolding can be configured to provide a low-profile entry in a collapsed configuration through the single point of entry through the annulus. The expanding including laterally expanding at least a portion of a first support and at least a portion of a second support away from each other; and, vertically expanding at least a portion of the first support or at least a portion of the second support for a distraction of the intervertebral space. The lateral movement can include a rotation at a point of intersection between the first support and the second support, the intersection being biased anteriorly in the intevertebral space to facilitate the adding of the grafting material.
摘要翻译：提供了一种后视可扩展的脚手架，用于使用微创程序来支撑椎间盘空间。脚手架可以被配置为通过通过环空的单个进入点在折叠构型中提供低调条目。膨胀包括横向膨胀第一支撑件的至少一部分和第二支撑件的至少一部分彼此远离; 并且使所述第一支撑件的至少一部分或所述第二支撑件的至少一部分垂直展开以使所述椎间空间分散。横向运动可以包括在第一支撑件和第二支撑件之间的交叉点处的旋转，该交叉点在前述空间中向前偏置以便于接合材料的添加。

9. 发明公开

EP2931185A1 A BONE GRAFT DISTRIBUTION SYSTEM 有权转让
标题翻译：骨植入分配系统
公开(公告)号：EP2931185A1
公开(公告)日：2015-10-21
申请号：EP13862126.3
申请日：2013-12-05
申请人： Ouroboros Medical Inc. , To, John , Flynn, John J. , Birkmeyer, Paul J.
发明人： TO, John , FLYNN, John, J. , BIRKMEYER, Paul, J.
IPC分类号： A61F2/44 , A61B17/70 , A61F2/28
CPC分类号： A61F2/447 , A61F2/30965 , A61F2/441 , A61F2/442 , A61F2/4611 , A61F2/4684 , A61F2002/2817 , A61F2002/2835 , A61F2002/30019 , A61F2002/30556 , A61F2002/30579 , A61F2002/30581 , A61F2002/30598 , A61F2002/30777 , A61F2002/30779 , A61F2002/30785 , A61F2002/4435 , A61F2002/444 , A61F2002/4475 , A61F2310/00011 , A61F2310/00023 , A61F2310/00029 , A61F2310/00047 , A61F2310/00053 , A61F2310/00071 , A61F2310/00179 , A61F2310/00293
摘要： A system for distributing bone graft material in an intervertebral disc space is provided having a central beam having a proximal portion having an end, a grafting portion having a top and a bottom, a distal portion having a end, a central beam axis, a graft distribution channel having an entry port at the end of the proximal portion, a top exit port at the top of the grafting portion, and a bottom exit port at the bottom of the grafting portion. These systems can also include a laterovertically-expanding frame operable for a reversible collapse from an expanded state into a collapsed state. The expanded state, for example, can be configured to have an open graft distribution window that at least substantially closes upon the reversible collapse.

10. 发明公开

EP2785264A1 SAFE CUTTING HEADS AND SYSTEMS FOR FAST REMOVAL OF A TARGET TISSUE 有权转让
标题翻译： SAFE切割头以及对靶组织的快速清除系统
公开(公告)号：EP2785264A1
公开(公告)日：2014-10-08
申请号：EP12853751.1
申请日：2012-08-22
申请人： Ouroboros Medical Inc.
发明人： TO, John
IPC分类号： A61B17/3205 , A61B17/3209 , A61B17/34 , A61B17/70
CPC分类号： A61B17/3205 , A61B17/320016 , A61B17/32002 , A61B2017/00261 , A61B2017/00738 , A61B2017/320064 , A61B2090/08021 , A61B2217/002 , A61F2/44 , A61F2002/444
摘要： A safe and efficient cutting heads for removing a target tissue from a subject during a surgical procedure are provided, the cutting heads composing a part of systems that address several problems, including clogging of state-of-the-art systems during removal of such tissue, for example. The target tissue can include any tissue that is accessible through a small surgical opening, for example, a joint tissue such as a meniscus or an intervertebral tissue, such as a nucleus pulposus. The devices can be referred to as orthopedic tissue removal devices having cutting heads associated with vacuum systems, making the systems useful in several procedures, including X-LIF (lateral approach to an intervertebral fusions) procedures, T-LIF (transforaminal approach to intervertebral fusions) procedures, P-LIF (posterior approach to intervertebral fusions), and a percutaneous, transforaminal approach (Kambin triangle access).

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