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1. 发明申请

WO2012001383A1 IMPROVEMENTS IN OR RELATING TO OPHTHALMOLOGY 审中-公开
标题翻译：改善或与眼科有关
公开(公告)号：WO2012001383A1
公开(公告)日：2012-01-05
申请号：PCT/GB2011/051039
申请日：2011-06-02
申请人： OPTOS PLC. , WALL, Robert , SWAN, Derek , GRAY, Dan
发明人： WALL, Robert , SWAN, Derek , GRAY, Dan
IPC分类号： A61B3/12 , A61F9/007 , G02B26/10 , G02B27/00 , A61B3/00
CPC分类号： A61B3/0008 , A61B3/12 , A61B3/14 , G02B6/0006
摘要： The invention provides an apparatus and method for illuminating, imaging and treating the retina of an eye. The apparatus (10) comprises at least one light source (16), wherein the at least one light source (16) is adapted to provide collimated light (20) from a plurality of point sources (22), and wherein each point source (22) lies on an arc (18), and wherein the at least one light source (16) is configured to direct collimated light (20) from each point source (22) along the radius (24) of the arc (18) towards a centre point (26) of the arc (18), and wherein, in use, the apparatus (10) is arranged such that the centre point (26) of the arc (18) is substantially coincident with the pupillary point (40) of the eye (14), such that collimated light (20) is transmitted from the point source (22) through the pupillary point (40) of the eye (14) to illuminate the retina (12).
摘要翻译：本发明提供了一种照明，成像和治疗眼睛视网膜的装置和方法。所述设备（10）包括至少一个光源（16），其中所述至少一个光源（16）适于从多个点源（22）提供准直光（20），并且其中每个点源 22）位于弧（18）上，并且其中所述至少一个光源（16）被配置为沿着所述弧（18）的半径（24）将准直光（20）从每个点源（22）引导朝向电弧（18）的中心点（26），并且其中在使用中，所述设备（10）布置成使得所述电弧（18）的中心点（26）与所述瞳孔点（40）基本重合，使得准直光（20）从点源（22）通过眼睛（14）的瞳孔点（40）传输以照亮视网膜（12）。

2. 发明申请

WO2011135348A2 IMPROVEMENTS IN OR RELATING TO SCANNING OPHTHALMOSCOPES 审中-公开
标题翻译：改善或与扫描眼镜相关
公开(公告)号：WO2011135348A2
公开(公告)日：2011-11-03
申请号：PCT/GB2011/050818
申请日：2011-04-26
申请人： OPTOS PLC. , THOMSON, Martin , SWAN, Derek , GRAY, Dan , PEMBERTON, Stephen
发明人： THOMSON, Martin , SWAN, Derek , GRAY, Dan , PEMBERTON, Stephen
IPC分类号： A61B3/12
CPC分类号： A61B3/13 , A61B3/1025
摘要： The present invention provides a scanning ophthalmoscope for scanning the retina of an eye and a method of scanning the retina of an eye. The ophthalmoscope (10) comprises a source of collimated light (12), a first scanning element (14), a second scanning element (16) and a scan relay device (18) having two foci (18a, 18b). The source of collimated light (12), the first and second scanning elements (14, 16) and the scan relay device (18) combine to provide a two-dimensional collimated light scan (21) from an apparent point source (19). The scanning ophthalmoscope (10) further comprises a scan transfer device (20), wherein the scan transfer device (20) has two foci (20a, 20b) and at least one vertex (20c) and the apparent point source (19) is provided at a first focus (20a) of the scan transfer device (20) and an eye (22) is accommodated at a second focus (20b) of the scan transfer device (20), and wherein the scan transfer device (20) transfers the two-dimensional collimated light scan (21) from the apparent point source (19) into the eye (22). The two foci (18a, 18b) of the scan relay device (18) and the two foci (20a, 20b) of the scan transfer device (20) define a first plane and the two foci (20a, 20b) and the at least one vertex (20c) of the scan transfer device (20) define a second plane and wherein the first and second planes are substantially parallel.
摘要翻译：本发明提供了一种用于扫描眼睛的视网膜的扫描检眼镜和扫描眼睛的视网膜的方法。检眼镜（10）包括准直光源（12），第一扫描元件（14），第二扫描元件（16）和具有两个焦点（18a，18b）的扫描中继装置（18）。准直光源（12），第一和第二扫描元件（14,16）和扫描中继装置（18）组合以提供来自视点（19）的二维准直光扫描（21）。扫描检眼镜（10）还包括扫描传送装置（20），其中扫描传送装置（20）具有两个焦点（20a，20b）和至少一个顶点（20c），并且提供视点源（19）在扫描传送装置（20）的第一焦点（20a）和眼睛（22）被容纳在扫描传送装置（20）的第二焦点（20b）处，并且其中扫描传送装置（20）从视点（19）到眼睛（22）的二维准直光扫描（21）。扫描中继装置（18）的两个焦点（18a，18b）和扫描传送装置（20）的两个焦点（20a，20b）限定第一平面，并且两个焦点（20a，20b）至少扫描传送装置（20）的一个顶点（20c）限定第二平面，并且其中第一和第二平面基本平行。

3. 发明申请

WO2012001382A1 IMPROVEMENTS IN OR RELATING TO OPHTHALMOLOGY 审中-公开
标题翻译：改善或与眼科有关
公开(公告)号：WO2012001382A1
公开(公告)日：2012-01-05
申请号：PCT/GB2011/051038
申请日：2011-06-02
申请人： OPTOS PLC. , GRAY, Dan , PEMBERTON, Stephen , SWAN, Derek , THOMSON, Martin
发明人： GRAY, Dan , PEMBERTON, Stephen , SWAN, Derek , THOMSON, Martin
IPC分类号： A61B3/00 , A61B3/12 , G02B26/12 , G02B27/00 , A61F9/00
CPC分类号： A61B3/1025 , A61B3/12 , A61B3/1225 , A61B2562/028 , G02B26/101 , G02B26/105
摘要： The invention provides an apparatus and method for scanning, imaging and treating the retina of an eye. The apparatus (10) comprises a source of collimated light (14), a two-dimensional scanning device (16) having two axes of rotation (16a, 16b), wherein the axes of rotation (16a, 16b) are orthogonal and substantially planar, and wherein the source of collimated light (14) and the two-dimensional scanning device (16) combine to provide a two-dimensional collimated light scan from a point source (22). The apparatus (10) further comprises a scan transfer device (18), wherein the scan transfer device (18) has two foci (18a, 18b) and the point source (22) is provided at a first focus point (18a) of the scan transfer device (18) and an eye (12) is accommodated at a second focus point (18b) of the scan transfer device (18), and wherein the scan transfer device (18) transfers the two-dimensional collimated light scan from the point source (22) into the eye (12).
摘要翻译：本发明提供了一种用于扫描，成像和治疗眼睛视网膜的装置和方法。装置（10）包括准直光源（14），具有两个旋转轴线（16a，16b）的二维扫描装置（16），其中旋转轴线（16a，16b）是正交的并且基本上是平面的，并且其中准直光源（14）和二维扫描装置（16）组合以提供来自点源（22）的二维准直光扫描。所述装置（10）还包括扫描传送装置（18），其中所述扫描传送装置（18）具有两个焦点（18a，18b），并且所述点光源（22）设置在所述扫描传送装置的第一焦点（18a）扫描传送装置（18）和眼睛（12）容纳在扫描传送装置（18）的第二焦点（18b）处，并且其中扫描传送装置（18）将二维准直光扫描从点源（22）进入眼睛（12）。

4. 发明申请

WO2016120607A1 IMPROVEMENTS RELATING TO RETINAL TREATMENT 审中-公开
标题翻译：关于治疗的改善
公开(公告)号：WO2016120607A1
公开(公告)日：2016-08-04
申请号：PCT/GB2016/050163
申请日：2016-01-26
申请人： OPTOS PLC
发明人： SWAN, Derek
IPC分类号： A61F9/008
CPC分类号： A61F9/00821 , A61B3/12 , A61F2009/00863 , A61F2009/00878 , A61F2009/00897
摘要： A method of determining control parameters of a retinal treatment system comprising acquiring an image of a retina of a subject's eye using an imaging laser and an optical system of the retinal treatment system, presenting an image of the retina to a user of the retinal treatment system, receiving from the user location data of the retinal image that locates at least one treatment site of the retina, receiving from the user a required laser light pattern for use on the treatment site, using the location data to determine a location control parameter which causes the optical system to direct laser light from a treatment laser of the retinal treatment system to the treatment site, and using the required laser light pattern to determine a pattern control parameter which causes the treatment laser to produce a laser light pattern which passes through the optical system and results in the required laser light pattern at the treatment site.
摘要翻译：一种确定视网膜处理系统的控制参数的方法，包括使用成像激光器和视网膜处理系统的光学系统获取对象眼睛的视网膜的图像，将视网膜的图像呈现给视网膜处理系统的用户从所述用户位置接收位于所述视网膜的至少一个治疗部位的所述视网膜图像的数据，从所述用户接收在所述治疗部位使用的所需激光图案，使用所述位置数据来确定引起的位置控制参数所述光学系统将来自所述视网膜处理系统的处理激光器的激光引导到所述处理部位，并且使用所需的激光图案来确定使所述处理激光器产生通过所述光学部件的激光图案的图案控制参数系统，并在治疗部位产生所需的激光模式。

5. 发明申请

WO2020127233A1 DETECTION OF PATHOLOGIES IN OCULAR IMAGES 审中-公开
公开(公告)号：WO2020127233A1
公开(公告)日：2020-06-25
申请号：PCT/EP2019/085608
申请日：2019-12-17
申请人： OPTOS PLC
发明人： VAN HEMERT, Jano , SWAN, Derek
IPC分类号： G06K9/00 , A61B5/00 , A61B3/00 , G06K9/62 , A61B3/10 , A61B3/18
摘要： A computer-implemented method of searching for a region (410) indicative of a pathology in an image (400) of a portion of an eye acquired by an ocular imaging system (420), the method comprising: receiving (S10) image data defining the image; searching (S12) for the region in the image by processing the received image data using a learning algorithm; and in case a region in the image that is indicative of the pathology is found: determining (S14) a location of the region in the image; generating (S16) an instruction for an eye measurement apparatus to perform a measurement on the portion of the eye to generate measurement data, using a reference point based on the determined location for setting a location of the measurement on the portion of the eye; and receiving (S18) the measurement data from the eye measurement apparatus.

6. 发明申请

WO2016038332A1 IMPROVEMENTS IN AND RELATING TO OPHTHALMOSCOPES 审中-公开
标题翻译：改善和相关眼科手术
公开(公告)号：WO2016038332A1
公开(公告)日：2016-03-17
申请号：PCT/GB2015/052450
申请日：2015-08-25
申请人： OPTOS PLC
发明人： MUYO, Gonzalo , SWAN, Derek
IPC分类号： A61B3/10
CPC分类号： A61B3/1025 , A61B3/135
摘要： An ophthalmoscope (10) comprising a light source (12), a first scanner (14), a first scan transfer element (16), a second scanner (18), and a second scan transfer element (20), which provide a two-dimensional scan of incident light from an apparent point source at a pupillary point of an eye (22) onto the fundus of the eye, and which descan a two- dimensional scan of return light from the fundus of the eye to provide return light from an apparent point source at the first scanner,wherein the first scan transfer element comprises a free-form element which has a shape defined to provide aberration correction of the return light from the fundus of the eye.
摘要翻译：一种检眼镜（10），包括光源（12），第一扫描器（14），第一扫描传输元件（16），第二扫描器（18）和第二扫描传输元件（20）从眼睛的瞳孔点（22）的明显点源的入射光到眼睛的眼底的二维扫描，并且从眼睛的眼底进行二维扫描返回光以提供来自眼睛的返回光在第一扫描器处的视点源，其中第一扫描传送元件包括自由形元件，该自由形元件具有被限定为提供来自眼底的返回光的像差校正的形状。

7. 发明申请

WO2014096835A1 IMPROVEMENTS IN AND RELATING TO OPHTHALMOSCOPES 审中-公开
标题翻译：改善和相关眼科手术
公开(公告)号：WO2014096835A1
公开(公告)日：2014-06-26
申请号：PCT/GB2013/053366
申请日：2013-12-19
申请人： OPTOS PLC
发明人： SWAN, Derek , VAN HEMERT, Jano , VERHOEK, Michael , MUYO, Gonzalo
IPC分类号： A61B3/14 , A61B3/00 , A61B3/12
CPC分类号： A61B3/0025 , A61B3/12 , A61B3/14
摘要： A method of determining a correction for image distortion of an ophthalmology system is provided, comprising creating a target, computing an image of the target, using the ophthalmology system to scan the target to create a distorted image of the target, and comparing the computed image of the target with the distorted image of the target to determine the correction for image distortion of the ophthalmology system. The invention further provides a method of correcting distortion in a retinal image acquired using an ophthalmology system, a corrected retinal image and an image distortion correction system.
摘要翻译：提供了一种确定眼科系统的图像失真校正的方法，包括使用眼科系统创建目标，计算目标的图像，以扫描目标以创建目标的失真图像，以及将计算出的图像的目标的畸变图像以确定眼科系统的图像失真的校正。本发明还提供一种校正使用眼科系统，校正的视网膜图像和图像失真校正系统获取的视网膜图像中的失真的方法。

8. 发明申请

WO2016005763A1 OPHTHALMOSCOPES 审中-公开
标题翻译：检眼镜
公开(公告)号：WO2016005763A1
公开(公告)日：2016-01-14
申请号：PCT/GB2015/052001
申请日：2015-07-10
申请人： OPTOS PLC
发明人： SWAN, Derek , MUYO, Gonzalo , GORMAN, Alistair
IPC分类号： A61B3/10 , A61B3/12
CPC分类号： A61B3/12 , A61B3/1025 , G02B26/105
摘要： An ophthalmoscope (1) and method for scanning a fundus (23) of an eye (9), comprising a light system (3) which produces linear light, a scanner (5) which receives at least some of the linear light and is movable about a scan axis to produce a 1D scan of the at least some linear light, and a scan transfer system (7) which receives the 1D scan from the scanner and transfers the 1D scan to the eye, wherein the scanner is positioned in the ophthalmoscope such that it receives the at least some of the linear light substantially along the scan axis, the scan transfer system positioned in the ophthalmoscope such that a pupil of the eye is provided at a focal point of the system, and the scanner is positioned in the ophthalmoscope and the scan transfer system is configured to transfer the 1D scan from the scanner through the focal point at the eye pupil and onto the eye fundus.
摘要翻译：一种用于扫描眼睛（9）的眼底（23）的检眼镜（1）和方法，包括产生线性光的光系统（3），扫描器（5），其接收至少一些线性光并且是可移动的围绕扫描轴产生至少一些线性光的1D扫描;以及扫描传输系统（7），其从扫描仪接收1D扫描并将1D扫描传送到眼睛，其中扫描器位于检眼镜中使得其基本沿着扫描轴接收至少一些线性光，扫描传送系统定位在检眼镜中，使得眼睛的瞳孔设置在系统的焦点处，并且扫描仪位于检眼仪和扫描传输系统被配置为将来自扫描仪的1D扫描通过眼睛瞳孔处的焦点传送到眼底。

9. 发明申请

WO2014053824A1 IMPROVEMENTS IN OR RELATING TO SCANNING LASER OPHTHALMOSCOPES 审中-公开
标题翻译：改善或相关于扫描激光眼科手术
公开(公告)号：WO2014053824A1
公开(公告)日：2014-04-10
申请号：PCT/GB2013/052556
申请日：2013-10-01
申请人： OPTOS PLC
发明人： BROWN, William , WILLIAMS, Mike , CORCORAN, Anthony , SWAN, Derek
IPC分类号： A61B3/10
CPC分类号： A61B3/102 , A61B3/1015 , A61B3/1025 , A61B3/1225 , A61B3/14
摘要： A scanning laser ophthalmoscope (SLO) for imaging the retina of an eye comprises a source (12) of collimated light, a scanning device (14, 16, 1328, 1319), a scan transfer device (20) and a detector (1310). The scan transfer device has a first focus (16) at which an apparent point source is provided and a second focus (24) at which an eye (524, 1324) may be accommodated. The scan transfer device transfers a two-dimensional collimated light scan from the apparent point source into the eye. An optical coherence tomography (OCT) system (900) is combined with the SLO, the OCT system providing OCT reference and sample beams. The OCT sample beam (902) propagates along the same optical path as of the SLO collimated light through the scan transfer device. An aberration compensator (1204, 1316) automatically compensates for systematic aberrations and/or changes in wavefront introduced by scanning elements and the scan transfer device as a function of scan angle.
摘要翻译：用于对眼睛的视网膜成像的扫描激光检眼镜（SLO）包括准直光源（12），扫描装置（14,16,1328,1319），扫描传送装置（20）和检测器（1310）。扫描传送装置具有第一焦点（16），在该第一焦点处提供视点信号源，第二焦点（24）可以容纳眼睛（524,1324）。扫描传送装置将来自视点的二维准直光扫描转移到眼睛中。光学相干断层扫描（OCT）系统（900）与SLO组合，OCT系统提供OCT参考和采样光束。 OCT采样光束（902）沿着与通过扫描传送装置的SLO准直光相同的光路传播。像差补偿器（1204,1316）自动补偿由扫描元件和扫描传送装置引起的波前的系统像差和/或变化作为扫描角度的函数。

10. 发明公开

EP2903498A1 IMPROVEMENTS IN OR RELATING TO SCANNING LASER OPHTHALMOSCOPES 有权转让
标题翻译： VERBESSERUNGEN AN ODER IM ZUSAMMENHANG MIT SCANNING-LASEROPHTHALMOSKOPEN
公开(公告)号：EP2903498A1
公开(公告)日：2015-08-12
申请号：EP13779330.3
申请日：2013-10-01
申请人： Optos PLC
发明人： BROWN, William , WILLIAMS, Mike , CORCORAN, Anthony , SWAN, Derek
IPC分类号： A61B3/10
CPC分类号： A61B3/102 , A61B3/1015 , A61B3/1025 , A61B3/1225 , A61B3/14
摘要： A scanning laser ophthalmoscope (SLO) for imaging the retina of an eye comprises a source (12) of collimated light, a scanning device (14, 16, 1328, 1319), a scan transfer device (20) and a detector (1310). The scan transfer device has a first focus (16) at which an apparent point source is provided and a second focus (24) at which an eye (524, 1324) may be accommodated. The scan transfer device transfers a two-dimensional collimated light scan from the apparent point source into the eye. An optical coherence tomography (OCT) system (900) is combined with the SLO, the OCT system providing OCT reference and sample beams. The OCT sample beam (902) propagates along the same optical path as of the SLO collimated light through the scan transfer device. An aberration compensator (1204, 1316) automatically compensates for systematic aberrations and/or changes in wavefront introduced by scanning elements and the scan transfer device as a function of scan angle.
摘要翻译：用于对眼睛的视网膜成像的扫描激光检眼镜（SLO）包括准直光源（12），扫描装置（14,16,1328,1319），扫描传送装置（20）和检测器（1310）。扫描传送装置具有第一焦点（16），在该第一焦点处提供视点信号源，并且第二焦点（24）可以容纳眼睛（524,1324）。扫描传送装置将来自视点的二维准直光扫描传输到眼睛。光学相干断层扫描（OCT）系统（900）与SLO组合，OCT系统提供OCT参考和样本光束。 OCT采样光束（902）沿着与通过扫描传送装置的SLO准直光相同的光路传播。像差补偿器（1204,1316）自动补偿由扫描元件和扫描传送装置引起的波阵面的系统像差和/或变化作为扫描角度的函数。

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