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1. 发明申请

WO2013022917A3 METHOD FOR PROCESSING SAMPLES HELD BY A NANOMANIPULATOR 审中-公开
标题翻译：处理纳米管的样品的方法
公开(公告)号：WO2013022917A3
公开(公告)日：2013-04-11
申请号：PCT/US2012049908
申请日：2012-08-08
申请人： OMNIPROBE INC , HARTFIELD CHERYL , MOORE THOMAS , MILLER BRIAN
发明人： HARTFIELD CHERYL , MOORE THOMAS , MILLER BRIAN
IPC分类号： G01N1/36 , G01B9/04 , H01J37/20
CPC分类号： G01N1/32 , B82Y10/00 , B82Y40/00 , G01N1/286 , G01N2001/2886 , G02B21/32 , H01J37/20 , H01J2237/0216 , H01J2237/208 , H01J2237/31745
摘要： A method for processing a sample in a charged-particle beam microscope. A sample is collected from a substrate and the sample is attached to the tip of a nanomanipulator. The sample is optionally oriented to optimize further processing. The nanomanipulator tip is brought into contact with a stabilizing support to minimize drift or vibration of the sample. The attached sample is then stabilized and available for preparation and analysis.
摘要翻译：一种在带电粒子束显微镜中处理样品的方法。从基底收集样品并将样品附着到纳米操纵器的尖端。该样本可选地被定向以优化进一步的处理。纳米操纵器尖端与稳定支架接触以使样品的漂移或振动最小化。附着的样品然后稳定并可用于制备和分析。

2. 发明申请

WO2011011659A3 VARIABLE-TILT TEM SPECIMEN HOLDER FOR CHARGED-PARTICLE BEAM INSTRUMENTS 审中-公开
标题翻译：用于带电粒子束仪器的变倾斜透射电子显微镜样品架
公开(公告)号：WO2011011659A3
公开(公告)日：2011-04-28
申请号：PCT/US2010043012
申请日：2010-07-23
申请人： OMNIPROBE INC , AMADOR GONZALO , MILLER BRIAN
发明人： AMADOR GONZALO , MILLER BRIAN
IPC分类号： H01J37/20 , H01J37/26
CPC分类号： H01J37/20 , H01J2237/20207 , H01J2237/31745 , H01J2237/31749
摘要： A variable-tilt specimen holder (100) for a charged particle instrument having a tilt stage (360), where the tilt stage (360) has a maximum range of tilt, a sample plate (280) affixed to the tilt stage (360), and an ion-beam column (320) having an ion-beam column axis. The variable-tilt specimen holder (100) has a base (110) for mounting to the sample plate (280), so that the base (110) is substantially parallel to the tilt stage (360). A rotatably supported pivot plate (140) has slots (210) for holding TEM specimens (270) or TEM grids holding specimens (270). The pivot plate (140) is rotatable so that the TEM specimens (270) held therein can be aligned with the axis of the ion beam column (320) for thinning of the specimen (270). The pivot plate (140) has a range of rotation sufficient to move the preferred axis (275) of thinning of the specimen (270) from a first position where the tilt stage (360) is placed at its maximum range of tilt and the angle between the preferred axis (275) of thinning of the specimen (270) and the axis of the ion beam column (320) is greater than zero, to a second position where the preferred axis (275) for thinning of the specimen (270) is substantially parallel to the axis of the ion-beam column (320).
摘要翻译：一种用于具有倾斜台（360）的带电粒子仪器的可变倾斜试样保持器（100），其中倾斜台（360）具有最大倾斜范围，固定到倾斜台（360）的样品板（280）和具有离子束列轴的离子束柱（320）。可变倾斜试样架（100）具有用于安装到试样板（280）的基座（110），使得基座（110）基本平行于倾斜台（360）。可旋转地支撑的枢轴板（140）具有用于容纳保持样本（270）的TEM样本（270）或TEM网格的狭槽（210）。枢轴板（140）是可旋转的，使得保持在其中的TEM样本（270）可以与离子束柱（320）的轴线对齐以使样本（270）变薄。枢转板（140）具有足以使试样（270）变薄的优选轴（275）从其中倾斜台（360）被放置在其最大倾斜范围处的第一位置移动的旋转范围，在样本（270）的变薄的优选轴（275）和离子束列（320）的轴之间的距离大于零的第二位置到用于使样本（270）变薄的优选轴（275）基本平行于离子束柱（320）的轴线。

3. 发明公开

EP2742334A4 METHOD FOR PROCESSING SAMPLES HELD BY A NANOMANIPULATOR 审中-公开
标题翻译：一种用于在纳操作器样品加工
公开(公告)号：EP2742334A4
公开(公告)日：2015-03-11
申请号：EP12822777
申请日：2012-08-08
申请人： OMNIPROBE INC
发明人： HARTFIELD CHERYL , MOORE THOMAS , MILLER BRIAN
IPC分类号： G01N1/32 , B82Y10/00 , B82Y40/00 , G01B9/04 , G01N1/28 , G02B21/32 , H01J37/20
CPC分类号： G01N1/32 , B82Y10/00 , B82Y40/00 , G01N1/286 , G01N2001/2886 , G02B21/32 , H01J37/20 , H01J2237/0216 , H01J2237/208 , H01J2237/31745

4. 发明专利

ES2561825T3 Péptidos 未知
公开(公告)号：ES2561825T3
公开(公告)日：2016-03-01
申请号：ES11766930
申请日：2011-09-23
申请人： DÍAZ-TORRES MARÍA R , DUNN-COLEMAN NIGEL STUART , MILLER BRIAN S
发明人： DUNN-COLEMAN NIGEL STUART , DIAZ-TORRES MARÍA R , MILLER BRIAN
IPC分类号： C07K14/37 , A61K39/35 , C07K14/415 , C07K14/435
摘要： Un péptido seleccionado de uno de: (i) SEC ID Nº: 196, 197, 198, 200, 201, 202, 203, 204, 205, 206, 207, 208, 209, 210; o (ii) SEC ID Nº: 211, 212, 213, 214, 215, 216, 217, 218, 219, 220, 221, 222, 223, 224, 225, 226, 227, 230, 231, 232, 233; para uso en un método de prevención o tratamiento de enfermedad alérgica provocada por el alérgeno proteico de Alternaria alternata Alt a 1.

5. 发明申请

WO9927107A2 GRAM-POSITIVE MICROORGANISM FORMATE PATHWAY 审中-公开
公开(公告)号：WO9927107A2
公开(公告)日：1999-06-03
申请号：PCT/US9824873
申请日：1998-11-19
申请人： GENENCOR INT , MILLER BRIAN , DIAZ TORRES MARIA
发明人： MILLER BRIAN , DIAZ-TORRES MARIA
IPC分类号： C12N15/09 , C07K14/32 , C12N1/21 , C12N9/00 , C12N9/10 , C12N9/80 , C12N15/31 , C12N15/75 , C12R1/07
CPC分类号： C12Y305/01031 , C07K14/32 , C12N9/80 , C12N15/75 , C12Y305/0101
摘要： The present invention relates to the formate transport system in gram-positive microorganisms and provides methods for the production of products in a gram-positive microorganism. The present invention also provides the nucleic acid and amino acid sequences of four molecules associated with formate transport, FTAP 1, FTAP 2, PurU and Def.
摘要翻译：本发明涉及革兰氏阳性微生物中的甲酸盐输送系统，并且提供了在革兰氏阳性微生物中产生产物的方法。本发明还提供了与甲酸转运相关的四种分子的核酸和氨基酸序列，FTAP 1，FTAP 2，PurU和Def。

6. 发明申请

WO2012038540A2 PEPTIDES 审中-公开
标题翻译：肽
公开(公告)号：WO2012038540A2
公开(公告)日：2012-03-29
申请号：PCT/EP2011066610
申请日：2011-09-23
申请人： ALERGENETICA SL , DUNN-COLEMAN NIGEL STUART , DIAZ-TORRES MARIA R , MILLER BRIAN
发明人： DUNN-COLEMAN NIGEL STUART , DIAZ-TORRES MARIA R , MILLER BRIAN
IPC分类号： C07K14/37 , A61K39/35 , C07K14/415 , C07K14/435
CPC分类号： C07K7/08 , A61K39/0002 , A61K39/35 , C07K7/06 , C07K14/37 , C07K14/415 , C07K14/435
摘要： The application discloses peptides capable of preventing or treating fungal disease, including fungal allergy disease.
摘要翻译：本申请公开了能够预防或治疗真菌性疾病（包括真菌性过敏性疾病）的肽。

7. 发明申请

WO9927107A9 GRAM-POSITIVE MICROORGANISM FORMATE TRANSPORTERS 审中-公开
公开(公告)号：WO9927107A9
公开(公告)日：2000-10-12
申请号：PCT/US9824873
申请日：1998-11-19
申请人： GENENCOR INT , MILLER BRIAN , DIAZ TORRES MARIA
发明人： MILLER BRIAN , DIAZ-TORRES MARIA
IPC分类号： C12N15/09 , C07K14/32 , C12N1/21 , C12N9/00 , C12N9/10 , C12N9/80 , C12N15/31 , C12N15/75 , C12R1/07 , C12N15/67 , C12N15/52
CPC分类号： C12Y305/01031 , C07K14/32 , C12N9/80 , C12N15/75 , C12Y305/0101
摘要： The present invention relates to the formate transport system in gram-positive microorganisms and provides methods for the production of products in a gram-positive microorganism. The present invention also provides the nucleic acid and amino acid sequences of four molecules associated with formate transport, FTAP 1, FTAP 2, PurU and Def.
摘要翻译：本发明涉及革兰氏阳性微生物中的甲酸盐输送系统，并且提供了在革兰氏阳性微生物中产生产物的方法。本发明还提供了与甲酸转运相关的四种分子的核酸和氨基酸序列，FTAP 1，FTAP 2，PurU和Def。

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