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1. 发明申请

WO2007104966A8 METHOD OF FORMING 审中-公开
标题翻译：形成方法
公开(公告)号：WO2007104966A8
公开(公告)日：2007-11-29
申请号：PCT/GB2007000870
申请日：2007-03-12
申请人： OCUTEC LTD , BOWERS RODERICK WILLIAM JONATH , GRAHAM NEIL BONNETTE , RASHID ABDUL
发明人： BOWERS RODERICK WILLIAM JONATH , GRAHAM NEIL BONNETTE , RASHID ABDUL
IPC分类号： C08J5/00
CPC分类号： G02B1/043 , A61L27/18 , C08L71/02
摘要： The present invention relates to a method of using non-macrogelled polymer-solvent combinations to form devices, in particular medical devices and / or cosmetic devices, more specifically contact lenses. The method of using polymer solvent combinations is suitable for forming useful 3D dimensionally stable structures which may include curved surfaces, which may be significantly different to those curved surfaces achieved by using simple meniscus effects.
摘要翻译：本发明涉及使用非聚凝胶聚合物 - 溶剂组合来形成装置，特别是医疗装置和/或化妆品装置，更具体地说是隐形眼镜的方法。使用聚合物溶剂组合的方法适用于形成有用的3D尺寸稳定的结构，其可以包括弯曲表面，其可以与通过使用简单的弯月面效应实现的那些曲面显着不同。

2. 发明申请

WO2011055110A8 POLYMERS FOR CONTACT LENSES 审中-公开
标题翻译：聚合物用于接触镜片
公开(公告)号：WO2011055110A8
公开(公告)日：2012-05-31
申请号：PCT/GB2010002026
申请日：2010-11-02
申请人： OCUTEC LTD , RASHID ABDUL , BOWERS RODERICK WILLIAM JONATHAN , TIPTON WADE , GRAHAM NEIL BONNETTE
发明人： RASHID ABDUL , BOWERS RODERICK WILLIAM JONATHAN , TIPTON WADE , GRAHAM NEIL BONNETTE
IPC分类号： C08G18/48 , C08G18/66 , G02B1/04
CPC分类号： C08G18/4833 , C08G18/6674 , C08G2220/00 , G02B1/043 , C08L75/08
摘要： The present invention relates to a thermoplastic polyurethane contact lens prepared from a mixture comprising: (a) at least one polyethylene glycol; (b) at least one di-isocyanate; and (c) at least one diol of formula (I): wherein n is an integer from 1 to 25; wherein the polyethylene glycol, di-isocyanate and diol are reacted under substantially anhydrous conditions. Further aspects of the invention relate to a process for preparing a contact lens. The invention also relates to a process for preparing a polyurethane xerogel in the form of a molded article, said process comprising the steps of: (i) preparing a reaction mixture comprising at least one polyethylene glycol, at least one di-isocyanate and at least one diol of formula I as described above; (ii) reacting the reaction mixture formed in step (i) under substantially anhydrous conditions to form a polyurethane xerogel; (iii) injection molding the polyurethane xerogel to form a molded article, (iv) hydrating the xerogel molded article to form a contact lens.
摘要翻译：本发明涉及由以下混合物制备的热塑性聚氨酯隐形眼镜：（a）至少一种聚乙二醇; （b）至少一种二异氰酸酯; 和（c）至少一种式（I）的二醇：其中n是1至25的整数; 其中聚乙二醇，二异氰酸酯和二醇在基本无水条件下反应。本发明的其它方面涉及一种制备隐形眼镜的方法。本发明还涉及一种制备模制品形式的聚氨酯干凝胶的方法，所述方法包括以下步骤：（i）制备包含至少一种聚乙二醇，至少一种二异氰酸酯和至少一种二异氰酸酯的反应混合物如上所述的一种式I的二醇; （ii）在基本上无水条件下使步骤（i）中形成的反应混合物反应形成聚氨酯干凝胶; （iii）注射成型聚氨酯干凝胶以形成模塑制品，（iv）将干凝胶模塑制品保湿以形成隐形眼镜。

3. 发明申请

WO2011051689A3 POLYMERS FOR CONTACT LENSES 审中-公开
标题翻译：用于隐形眼镜的聚合物
公开(公告)号：WO2011051689A3
公开(公告)日：2011-06-23
申请号：PCT/GB2010002018
申请日：2010-11-02
申请人： OCUTEC LTD , RASHID ABDUL , BOWERS RODERICK WILLIAM JONATHAN , TIPTON WADE , GRAHAM NEIL BONNETTE
发明人： RASHID ABDUL , BOWERS RODERICK WILLIAM JONATHAN , TIPTON WADE , GRAHAM NEIL BONNETTE
IPC分类号： C08G18/48 , C08G18/61 , C08K5/00 , G02B1/04
CPC分类号： C08G71/04 , C08G18/4825 , C08G18/4829 , C08G18/4833 , C08G18/61 , C08G2101/0091 , C08G2210/00 , G02B1/043 , C08L69/00
摘要： The present invention relates to a polyurethane polymer composition comprising polyethyleneglycol dialkyl ether. There is also provided a process for preparing a polyurethane. The invention also relates to a process for preparing a polyurethane xerogel in the form of a molded article, said process comprising the steps of: i. preparing a mixture of a. at least one polyethylene glycol or at least one polyol of formula (I), wherein at least three Of X1, X2, X3, X4 and X5 are each independently an OH-terminated group, and the remainder of X1, X2, X3, X4 and X5 are each independently H or absent, and Z is a central linking unit, a. at least one di- or poly-isocyanate, b. optionally at least one OH-terminated chain extender, and c. at least one polyethyleneglycol dialkyl ether; ii. dispensing the reaction mixture formed in step i) into a mold; iii. allowing the reaction mixture to react and cure; iv. removing the molded article from the mold; and v. hydrating the molded article.
摘要翻译：本发明涉及包含聚乙二醇二烷基醚的聚氨酯聚合物组合物。还提供了一种制备聚氨酯的方法。本发明还涉及制备模制品形式的聚氨酯干凝胶的方法，所述方法包括以下步骤：i。准备一种混合物。至少一种聚乙二醇或至少一种式（I）的多元醇，其中X 1，X 2，X 3，X 4和X 5中的至少三个各自独立地为OH-封端的基团，且X 1，X 2，X 3，X 4的剩余部分和X 5各自独立地为H或不存在，且Z为中心连接单元，a。至少一种二异氰酸酯或多异氰酸酯，b。任选至少一种OH-封端的增链剂，和c。至少一种聚乙二醇二烷基醚; II。将步骤i）中形成的反应混合物分配到模具中; III。使反应混合物反应并固化; IV。从模具中取出模制品; 和v。使模制品水合。

4. 发明申请

WO2011051690A2 POLYMERS FOR CONTACT LENSES 审中-公开
标题翻译：用于隐形眼镜的聚合物
公开(公告)号：WO2011051690A2
公开(公告)日：2011-05-05
申请号：PCT/GB2010002019
申请日：2010-11-02
申请人： OCUTEC LTD , RASHID ABDUL , BOWERS RODERICK WILLIAM JONATHAN , TIPTON WADE , GRAHAM NEIL BONNETTE
发明人： RASHID ABDUL , BOWERS RODERICK WILLIAM JONATHAN , TIPTON WADE , GRAHAM NEIL BONNETTE
IPC分类号： C08G18/48 , C08G18/61 , G02B1/04
CPC分类号： C08G18/61 , C08G18/4829 , C08G18/4833 , C08G18/4883 , C08G2210/00 , G02B1/043 , C08L75/04
摘要： The present invention relates to a polyurethane polymer prepared from a mixture comprising: (a) at least one polyol of formula (I), wherein at least three of X1, X2, X3, X4 and X5 are each independently an OH-terminated polyoxyalkylene group, and the remainder of X1, X2, X3. X4 and X5 are each independently H or absent, and Z is a central linking unit; (b) at least one di-or poly-isocyanate; and (c) optionally at least one OH-terminated chain extender. Further aspects of the invention relate to a process for preparing a polyurethane, and to a process for preparing a contact lens.
摘要翻译：（a）至少一种式（I）的多元醇，其中X 1，X 2，X 3，X 4和X 5中的至少三个各自独立地为OH-封端的聚氧化烯基团，以及X1，X2，X3的其余部分。 X 4和X 5各自独立地为H或不存在，且Z为中心连接单元; （b）至少一种二或多异氰酸酯; 和（c）任选至少一种OH-封端的增链剂。本发明的其它方面涉及制备聚氨酯的方法，以及制备隐形眼镜的方法。

5. 发明申请

WO2012143695A3 POLYMERS FOR CONTACT LENSES 审中-公开
标题翻译：聚合物用于接触镜片
公开(公告)号：WO2012143695A3
公开(公告)日：2013-01-03
申请号：PCT/GB2012000391
申请日：2012-04-19
申请人： OCUTEC LTD , RASHID ABDUL , GRAHAM NEIL , BOWERS RODERICK
发明人： RASHID ABDUL , GRAHAM NEIL , BOWERS RODERICK
IPC分类号： C08G18/28 , C08G18/48 , C08G18/66 , G02B1/04
CPC分类号： C08G18/283 , C08G18/284 , C08G18/2865 , C08G18/4833 , C08G18/6674 , C08G18/6677 , C08G2101/0091 , C08G2210/00 , G02B1/043 , C08L75/04
摘要： The present invention relates to a polyurethane polymer compositions comprising polyethylene glycol) monoalkyl ether. The compositions may be either crosslinked (suitable for reaction cast moulding) or thermoplastic (suitable for injection and/or compression moulding). Either of the above varieties may contain carbinol terminated polydimethyl siloxane components. There is also provided a process for preparing such a polyurethane polymer composition. The invention also relates to a process for preparing a polyurethane xerogel in the form of a molded article, said process comprising the steps of. i. preparing a mixture of a. at least one poly(ethylene glycol) and/or at least one polyol or macropolyol having a functionality greater than 2, or a mixture of such polyols or macropolyols having a functionality of greater than 2, b. at least one di-or poly-isocyanate, c. optionally at least one OH-terminated chain extender, d. optionally an additional compound comprising at least one hydroxyl group and at least one primary or secondary amine group, and e. at least one poly(ethylene glycol) monoalkyl ether; ii. dispensing the reaction mixture formed in step i) into a mold; iii. allowing the reaction mixture to react and cure; iv. removing the molded article from the mold; and v. hydrating the molded article. Optionally the process may comprise the step of hydrating the molded article to form a hydrated article.
摘要翻译：本发明涉及包含聚乙二醇单烷基醚的聚氨酯聚合物组合物。组合物可以是交联的（适合于反应浇铸成型）或热塑性的（适合于注射和/或压塑）。上述任何一种都可能含有甲醇封端的聚二甲基硅氧烷组分。还提供了制备这种聚氨酯聚合物组合物的方法。本发明还涉及一种制备模塑制品形式的聚氨酯干凝胶的方法，所述方法包括以下步骤。一世。准备一种混合物。 b）具有官能度大于2的至少一种聚（乙二醇）和/或至少一种多元醇或大多元醇，或这些多官能团或大分子多醇的混合物，b。至少一种二异氰酸酯或多异氰酸酯，c。任选地至少一个OH-封端的扩链剂，d。任选的包含至少一个羟基和至少一个伯或仲胺基团的另外的化合物，至少一种聚（乙二醇）单烷基醚; II。将步骤i）中形成的反应混合物分配到模具中; III。使反应混合物反应并固化; IV。将模制品从模具中取出; 和v。水合成型制品。任选地，该方法可以包括水合模塑制品以形成水合制品的步骤。

6. 发明申请

WO2010151466A3 METHOD AND SYSTEM FOR CONTROLLING RADIO FREQUENCY POWER 审中-公开
标题翻译：用于控制无线电频率的方法和系统
公开(公告)号：WO2010151466A3
公开(公告)日：2011-11-17
申请号：PCT/US2010038790
申请日：2010-06-16
申请人： MKS INSTR INC , NAGARKATTI SIDDHARTH , TIAN FENG , LAM DAVID , RASHID ABDUL , BENZERROUK SOUHEIL , BYSTRYAK ILYA , MENZER DAVID , SCHUSS JACK J , AMBROSINA JESSE E
发明人： NAGARKATTI SIDDHARTH , TIAN FENG , LAM DAVID , RASHID ABDUL , BENZERROUK SOUHEIL , BYSTRYAK ILYA , MENZER DAVID , SCHUSS JACK J , AMBROSINA JESSE E
IPC分类号： H02J17/00
CPC分类号： H03K5/01 , H03F3/189 , H03F3/217 , H03F2200/105 , H03F2200/375 , H03F2200/387 , H03G3/3047
摘要： A method for controlling pulsed power that includes measuring a first pulse of power from a power amplifier to obtain data. The method also includes generating a first signal to adjust a second pulse of delivered power, the first signal correlated to the data to minimize a power difference between a power set point and a substantially stable portion of the second pulse. The method also includes generating a second signal to adjust the second pulse of delivered power, the second signal correlated to the data to minimize an amplitude difference between a peak of the second pulse and the substantially stable portion of the second pulse.
摘要翻译：一种用于控制脉冲功率的方法，包括从功率放大器测量第一功率脉冲以获得数据。该方法还包括产生第一信号以调整输出功率的第二脉冲，第一信号与数据相关，以最小化功率设定点与第二脉冲的基本稳定部分之间的功率差。该方法还包括产生第二信号以调整传递功率的第二脉冲，第二信号与数据相关，以最小化第二脉冲的峰值与第二脉冲的基本上稳定的部分之间的幅度差异。

7. 发明申请

WO2012096939A3 HIGHLY CONCENTRATED LIQUID ACETAMINOPHEN SOLUTIONS 审中-公开
标题翻译：高浓度液体乙胺阿诺芬溶液
公开(公告)号：WO2012096939A3
公开(公告)日：2012-10-18
申请号：PCT/US2012020750
申请日：2012-01-10
申请人： ENSPIRE GROUP LLC , RASHID ABDUL , TRAN MINH
发明人： RASHID ABDUL , TRAN MINH
IPC分类号： A61K9/48 , A61K9/20 , A61K9/22 , A61K31/133 , A61K31/135 , A61K31/137 , A61K31/166
CPC分类号： A61K9/4866 , A61K9/4858 , A61K31/167
摘要： Liquid softgel fill formulations include (i) 26-32% by weight acetaminophen, (ii) 47-51% by weight polyethylene glycol having an average molecular weight of 200-800, (iii) 3-7% by weight propylene glycol, (iv) 9-13% by weight Povidone K17, and (v) 6-10% by weight purified water. The fill formulations are free of alkali metal ions. Also disclosed are a method of preparing the above-described fill formulations and softgel capsules containing the same fill formulations.
摘要翻译：液体软凝胶填充制剂包括（i）26-32重量％对乙酰氨基酚，（ii）47-51重量％平均分子量为200-800的聚乙二醇，（iii）3-7重量％丙二醇，（ iv）9-13重量％的聚维酮K17，和（v）6-10重量％的净化水。填充配方不含碱金属离子。还公开了制备上述填充制剂和含有相同填充制剂的软胶囊的方法。

8. 发明申请

WO2008046625A3 ENCAPSULATION OF HEAT AND MOISTURE SENSITIVE SUBSTANCES 审中-公开
标题翻译：加热和水分敏感物质的包封
公开(公告)号：WO2008046625A3
公开(公告)日：2008-10-16
申请号：PCT/EP2007009050
申请日：2007-10-18
申请人： DSM IP ASSETS BV , KOWALSKI RAY EDWARD , SHEU SHAN-SHAN , RASHID ABDUL , BRONS CAROLINE , NASCIMENTO ELIZABETH
发明人： KOWALSKI RAY EDWARD , SHEU SHAN-SHAN , RASHID ABDUL , BRONS CAROLINE , NASCIMENTO ELIZABETH
IPC分类号： A23L1/00 , A61K8/00 , A61K9/10 , B01J13/02
CPC分类号： A23L1/3014 , A23L33/135 , A23P10/30 , A23V2002/00 , A61K8/11 , A61K8/375 , A61K8/553 , A61K8/922 , A61K8/925 , A61K8/99 , A61K9/10 , A61K9/48 , A61K9/4833 , A61K9/4875 , A61Q19/00 , B01J13/02 , A23V2200/3204 , A23V2200/224
摘要： The present invention relates to a method for preparing a suspension for the encapsulation of heat and moisture sensitive substances in capsules, sachets, droplets and food compositions. It also relates to methods for encapsulating, to the encapsulated products and to methods for storing the encapsulated products. The invention is extremely suitable for the encapsulation of microbial cultures. Cultures encapsulated in capsules prepared according to the method of the invention, will stay stable for a long time. At 25 degrees C they show a stability reduction of less than 1 log per month.
摘要翻译：本发明涉及一种制备用于在胶囊，小药囊，液滴和食物组合物中包封热和湿气敏感物质的悬浮液的方法。它还涉及用于封装封装产品的方法和用于存储封装产品的方法。本发明非常适用于微生物培养物的包封。包封在根据本发明方法制备的胶囊中的培养物将长时间保持稳定。在25摄氏度时，它们每月显示出小于1个对数的稳定性降低。

9. 发明申请

WO2014041323A1 POLYMERS FOR CONTACT LENSES 审中-公开
标题翻译：聚合物用于接触镜片
公开(公告)号：WO2014041323A1
公开(公告)日：2014-03-20
申请号：PCT/GB2013000379
申请日：2013-09-10
申请人： OCUTEC LTD
发明人： RASHID ABDUL , FRASER JOHN , HONEYMAN GORDON , MOHAMMED MUSSARRAT
IPC分类号： G02B1/04 , C08G18/48 , C08G18/61 , C08G18/66
CPC分类号： G02B1/043 , C08G18/4009 , C08G18/4833 , C08G18/61 , C08G18/6674 , C08G18/73 , C08G18/758 , C08G2101/0091 , C08G2210/00 , G02B2207/109 , C08L75/04 , C08L83/08
摘要： There is provided a polyurethane xerogel prepared from a mixture comprising: (a) at least one isocyanate, (b) at least one silicone containing compound of formula J: wherein at least one group represents a hydrocarbyl group and p represents an integer of from 1 to 40, or at least one R2 group represents a hydrocarbyl group and q represents an integer of from 1 to 40; and at least one R3 group represents a hydrocarbyl group and w represents an integer of from 1 to 40, or at least one R4 group represents a hydrocarbyl group and y represents an integer of from 1 to 40; (c) optionally one or more additional components; wherein the isocyanate and silicone containing compound are reacted under substantially anhydrous conditions. There is also provided a contact lens formed from the polyurethane xerogel.
摘要翻译：提供由混合物制备的聚氨酯干凝胶，其包含：（a）至少一种异氰酸酯，（b）至少一种含硅氧烷的式J化合物：其中至少一个基团表示烃基，p表示1的整数至40，或至少一个R 2基团表示烃基，q表示1至40的整数; 并且至少一个R 3基团表示烃基，w表示1〜40的整数，或至少一个R 4基团表示烃基，y表示1〜40的整数。（c）任选的一种或多种另外的组分; 其中异氰酸酯和含硅氧烷的化合物在基本上无水的条件下反应。还提供了由聚氨酯干凝胶形成的隐形眼镜。

10. 发明专利

SG11201501742TA POLYMERS FOR CONTACT LENSES 未知
公开(公告)号：SG11201501742TA
公开(公告)日：2015-04-29
申请号：SG11201501742T
申请日：2013-09-10
申请人： OCUTEC LTD
发明人： RASHID ABDUL , FRASER JOHN , HONEYMAN GORDON , MOHAMMED MUSSARRAT
IPC分类号： G02B1/04 , C08G18/48 , C08G18/61 , C08G18/66
摘要： There is provided a polyurethane xerogel prepared from a mixture comprising: (a) at least one isocyanate, (b) at least one silicone containing compound of formula J: wherein at least one group represents a hydrocarbyl group and p represents an integer of from 1 to 40, or at least one R2 group represents a hydrocarbyl group and q represents an integer of from 1 to 40; and at least one R3 group represents a hydrocarbyl group and w represents an integer of from 1 to 40, or at least one R4 group represents a hydrocarbyl group and y represents an integer of from 1 to 40; (c) optionally one or more additional components; wherein the isocyanate and silicone containing compound are reacted under substantially anhydrous conditions. There is also provided a contact lens formed from the polyurethane xerogel.

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