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1. 发明授权

EP2552934B1 CRYSTAL METABOLITE RECOVERY 有权
标题翻译：回收晶体代谢物
公开(公告)号：EP2552934B1
公开(公告)日：2015-07-15
申请号：EP11710201.2
申请日：2011-03-25
申请人： Novozymes A/S
发明人： PIND, Peter Frode , GLANVILLE, Simon , JAKOBSEN, Sune , KAASGAARD, Svend
IPC分类号： C07K1/14 , C07K1/30
CPC分类号： C07K1/30 , C07K1/306

2. 发明申请

WO2011120882A1 CRYSTAL METABOLITE RECOVERY 审中-公开
标题翻译：水晶代谢恢复
公开(公告)号：WO2011120882A1
公开(公告)日：2011-10-06
申请号：PCT/EP2011/054622
申请日：2011-03-25
申请人： NOVOZYMES A/S , PIND, Peter Frode , GLANVILLE, Simon , JAKOBSEN, Sune , KAASGAARD, Svend
发明人： PIND, Peter Frode , GLANVILLE, Simon , JAKOBSEN, Sune , KAASGAARD, Svend
IPC分类号： C07K1/14 , C07K1/30
CPC分类号： C07K1/30 , C07K1/306
摘要： A method for producing a crystalline and/or amorphous metabolite suspension from a cell fermentation broth in a continuous centrifuge process comprising (a) adding at a separate inlet to the centrifuge the fermentation broth comprising the cells and the metabolite of interest, wherein the metabolite is partly or wholly on crystalline and/or amorphous form; (b) adding at another inlet to the centrifuge an aqueous liquid comprising a salt and/or a carbohydrate having a higher density than the cells and a lower density than the metabolite of interest in its precipitated form; (c) removing the cells at a separate outlet to the centrifuge; and (d) removing the suspension comprising the crystalline and/or amorphous metabolite of interest at another outlet to the centrifuge.
摘要翻译：一种用于在连续离心方法中从细胞发酵肉汤生产结晶和/或无定形代谢物悬浮液的方法，包括（a）在离心机的单独入口处加入包含细胞和感兴趣代谢物的发酵液，其中代谢物为部分或全部为结晶和/或无定形形式; （b）在离心机的另一入口处加入包含比细胞密度高的盐和/或碳水化合物的水性液体，并且比其沉淀形式的感兴趣代谢物更低的密度; （c）将离开的单独出口处的细胞去除; 和（d）在离心机的另一个出口处将包含目的结晶和/或无定形代谢物的悬浮液除去。

3. 发明公开

EP2552934A1 CRYSTAL METABOLITE RECOVERY 有权
标题翻译：回收晶体代谢物
公开(公告)号：EP2552934A1
公开(公告)日：2013-02-06
申请号：EP11710201.2
申请日：2011-03-25
申请人： Novozymes A/S
发明人： PIND, Peter Frode , GLANVILLE, Simon , JAKOBSEN, Sune , KAASGAARD, Svend
IPC分类号： C07K1/14 , C07K1/30
CPC分类号： C07K1/30 , C07K1/306
摘要： A method for producing a crystalline and/or amorphous metabolite suspension from a cell fermentation broth in a continuous centrifuge process comprising (a) adding at a separate inlet to the centrifuge the fermentation broth comprising the cells and the metabolite of interest, wherein the metabolite is partly or wholly on crystalline and/or amorphous form; (b) adding at another inlet to the centrifuge an aqueous liquid comprising a salt and/or a carbohydrate having a higher density than the cells and a lower density than the metabolite of interest in its precipitated form; (c) removing the cells at a separate outlet to the centrifuge; and (d) removing the suspension comprising the crystalline and/or amorphous metabolite of interest at another outlet to the centrifuge.

4. 发明申请

WO2018185048A1 RECOVERY PROCESS 审中-公开
公开(公告)号：WO2018185048A1
公开(公告)日：2018-10-11
申请号：PCT/EP2018/058387
申请日：2018-04-03
申请人： NOVOZYMES A/S
发明人： GLANVILLE, Simon , PIND, Peter, Frode , JAKOBSEN, Sune , JOHANSEN, Lars , JACOBSEN, Carsten , ANDERSEN, Kim, Bruno , BEIER, Søren, Prip , RYPE, Jens, Ulrik
IPC分类号： C07K1/14 , C12N9/26 , C12N9/54
摘要： Disclosed is a method for recovering a desired fermentation product from a fermentation broth where the desired product has precipitated during the fermentation.

5. 发明申请

WO2015144932A1 ENZYME VARIANTS AND POLYNUCLEOTIDES ENCODING SAME 审中-公开
标题翻译： ENZYME变体和编码它的多核苷酸
公开(公告)号：WO2015144932A1
公开(公告)日：2015-10-01
申请号：PCT/EP2015/056896
申请日：2015-03-30
申请人： NOVOZYMES A/S
发明人： PEDERSEN, Poul Erik , PERSSON, Jon Martin , FRIIS, Esben Peter , GLANVILLE, Simon
IPC分类号： C07K1/06 , C07K1/107 , C07K2/00
CPC分类号： C12N9/54 , C11D3/386 , C11D3/38681 , C12Y304/00
摘要： The present invention relates to enzyme variants. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; methods of using the variants and composition comprising variants.
摘要翻译：本发明涉及酶变体。本发明还涉及编码这些变体的多核苷酸; 核酸构建体，载体和包含多核苷酸的宿主细胞; 使用包含变体的变体和组合物的方法。

6. 发明公开

EP3606936A1 RECOVERY PROCESS 有权
公开(公告)号：EP3606936A1
公开(公告)日：2020-02-12
申请号：EP18715649.2
申请日：2018-04-03
申请人： Novozymes A/S
发明人： GLANVILLE, Simon , PIND, Peter, Frode , JAKOBSEN, Sune , JOHANSEN, Lars , JACOBSEN, Carsten , ANDERSEN, Kim, Bruno , BEIER, Søren, Prip , RYPE, Jens, Ulrik
IPC分类号： C07K1/14 , C12N9/26 , C12N9/54

7. 发明公开

EP3122762A1 ENZYME VARIANTS AND POLYNUCLEOTIDES ENCODING SAME 审中-公开
标题翻译： ENZYMVARIANTEN UND POLYNUKLEOTIDE ZUR CODIERUNG DAVON
公开(公告)号：EP3122762A1
公开(公告)日：2017-02-01
申请号：EP15712656.6
申请日：2015-03-30
申请人： Novozymes A/S
发明人： PEDERSEN, Poul Erik , PERSSON, Jon Martin , FRIIS, Esben Peter , GLANVILLE, Simon
IPC分类号： C07K1/06 , C07K1/107 , C07K2/00
CPC分类号： C12N9/54 , C11D3/386 , C11D3/38681 , C12Y304/00
摘要： The present invention relates to enzyme variants. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; methods of using the variants and composition comprising variants.
摘要翻译：本发明涉及酶变体。本发明还涉及编码这些变体的多核苷酸; 核酸构建体，载体和包含多核苷酸的宿主细胞; 使用包含变体的变体和组合物的方法。

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