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    • 10. 发明授权
    • Hemoglobin test strip and analysis system
    • 血红蛋白试纸和分析系统
    • US07379167B2
    • 2008-05-27
    • US10364256
    • 2003-02-11
    • James A. MawhirtTed LeeSupinan R. NaphuketCharles E. TomsWai LawCatherine Cimini
    • James A. MawhirtTed LeeSupinan R. NaphuketCharles E. TomsWai LawCatherine Cimini
    • G01N33/48G01N21/00G01N21/77C12Q1/00
    • G01N21/8483B01L3/5023B01L2200/026B01L2300/0825G01N33/721
    • The apparatus and method for quickly measuring the hemoglobin content of a sample of blood uses a light reflectance measurement of the hemoglobin sample lysed in a membrane. The reflection is inversely proportional to hemoglobin concentration. A blood sample is loaded on to a nylon mesh and dispersed within a nylon membrane, both of which have been treated with a hemolyzing agent and surfactant, and air-dried. As soon as the blood sample contacts the reagent on the membrane, the red blood cells are lysed and the hemoglobin molecules are released and dispersed into the membrane by the action of surfactant. The hemoglobin apparatus emits light at 522 nm to the reflective surface of the membrane. The intensity of the reflected light is measured by a detector in less than 29 seconds. The intensity of the reflected light is converted to hemoglobin concentration, g/dL, or mmol/L by an interpolative comparison with stored reflection data indicative of known hemoglobin contents.
    • 用于快速测量血液样本血红蛋白含量的装置和方法使用在膜中裂解的血红蛋白样品的光反射测量。 反射与血红蛋白浓度成反比。 将血液样品装载到尼龙网上并分散在尼龙膜中,两者均用溶血剂和表面活性剂处理,并风干。 一旦血液样品与膜上的试剂接触,红细胞就被溶解,血红蛋白分子通过表面活性剂释放并分散到膜中。 血红蛋白装置在522nm处发射光到膜的反射表面。 反射光的强度由检测器在不到29秒内测量。 通过与指示已知血红蛋白含量的存储反射数据进行内插比较,将反射光的强度转换为血红蛋白浓度g / dL或mmol / L。