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2. 发明授权

US4891432A Phenoxy imidazole compound 失效
标题翻译：苯氧咪唑化合物
公开(公告)号：US4891432A
公开(公告)日：1990-01-02
申请号：US74290
申请日：1987-07-16
申请人： Noriki Ito , Yoshinobu Nagano , Akihiro Tanaka , Yoso Numasaki , Koichiro Takahashi
发明人： Noriki Ito , Yoshinobu Nagano , Akihiro Tanaka , Yoso Numasaki , Koichiro Takahashi
IPC分类号： A61K31/075 , A61K31/10 , A61K31/165 , A61K31/19 , A61K31/22 , A61K31/275 , A61K31/33 , A61K31/41 , A61K31/415 , A61K31/4184 , A61K31/433 , A61K31/44 , A61K31/4433 , A61K31/496 , A61K31/505 , A61P35/00 , C07C41/00 , C07C43/20 , C07C51/00 , C07C59/125 , C07C67/00 , C07C69/675 , C07C231/00 , C07C233/04 , C07C233/05 , C07C235/06 , C07C235/20 , C07C253/00 , C07C255/13 , C07C255/19 , C07C313/00 , C07C317/18 , C07C317/22 , C07C317/24 , C07C317/44 , C07C323/12 , C07C323/13 , C07C323/20 , C07C323/65 , C07C325/00 , C07C327/22 , C07D207/32 , C07D207/325 , C07D207/337 , C07D213/30 , C07D213/64 , C07D213/65 , C07D213/68 , C07D213/70 , C07D213/89 , C07D231/12 , C07D231/18 , C07D231/28 , C07D233/42 , C07D233/60 , C07D233/64 , C07D233/84 , C07D233/94 , C07D235/06 , C07D235/08 , C07D235/26 , C07D235/28 , C07D239/38 , C07D239/56 , C07D257/04 , C07D277/16 , C07D277/22 , C07D277/36 , C07D277/74 , C07D285/12 , C07D285/125 , C07D285/13 , C07D285/135 , C07D311/30 , C07D403/12 , C07D409/12 , C07D471/04 , C07D473/00 , C07D521/00
CPC分类号： C07D207/325 , C07D213/30 , C07D213/64 , C07D213/65 , C07D213/68 , C07D213/70 , C07D213/89 , C07D231/12 , C07D233/56 , C07D233/84 , C07D233/94 , C07D235/06 , C07D235/28 , C07D239/38 , C07D239/56 , C07D249/08 , C07D257/04 , C07D277/16 , C07D277/36 , C07D277/74 , C07D285/125 , C07D285/135 , C07D471/04 , C07D473/00
摘要： Novel phenoxy derivatives are provided which can be represented by the general formula: ##STR1## wherein the various substituents are as defined, and include compounds such as benzyl 6-[p-[5-(1-imidazolyl)pentyloxy]phenoxy]-2,2-dimethylhexanoate.The invention also encompasses pharmaceutical compositions containing the derivatives and their use in treating tumors.

3. 发明授权

US4886818A Inhibiting growth of tumors with certain substituted phenoxy dimethyl acids, esters or salts 失效
标题翻译：用某些取代的苯氧基二甲基酸，酯或盐抑制肿瘤的生长
公开(公告)号：US4886818A
公开(公告)日：1989-12-12
申请号：US198099
申请日：1988-05-24
申请人： Yoso Numasaki , Koichiro Takahashi , Isao Ohata
发明人： Yoso Numasaki , Koichiro Takahashi , Isao Ohata
IPC分类号： C07D233/60 , A61K31/415 , A61K31/44 , A61K31/4402 , A61K31/4406 , A61P35/00 , C07D213/63 , C07D213/64 , C07D213/65 , C07D521/00
CPC分类号： C07D213/64 , A61K31/415 , A61K31/44 , C07D213/65 , C07D231/12 , C07D233/56 , C07D249/08
摘要： This disclosure describes compositions of matter useful as growth inhibitors of transplanted tumors in mammals; and this invention discloses a method of inducing the regression and/or palliation of various types of tumors in mammals and which are susceptible to treatment by certain substituted phenoxy dimethyl alkanoic acids, esters or salts, said method comprising giving to said mammals an effective amount of a compound of the following formula: ##STR1## [wherein A represents an imidazolyl group or a pyridyl group,l represents 0 or 1,m and n each, which may be the same or different, represents an integer of 1 to 6, and,R represents a hydrogen atom or a lower alkyl group],or a salt thereof; the invention also discloses a method of inhibition (or prevention) of metastasis of the various cancers.The above formula compounds have low toxicity, and it is expected to apply various types of administration thereof such as oral administration and parenteral administration.

4. 发明授权

US4758580A Inhibiting growth of tumors with certain substituted phenoxy dimethyl alkanoic acids, esters or salts 失效
标题翻译：用某些取代的苯氧基二甲基链烷酸，酯或盐抑制肿瘤的生长
公开(公告)号：US4758580A
公开(公告)日：1988-07-19
申请号：US874547
申请日：1986-06-16
申请人： Yoso Numasaki , Koichiro Takahashi , Isao Ohata
发明人： Yoso Numasaki , Koichiro Takahashi , Isao Ohata
IPC分类号： C07D233/60 , A61K31/415 , A61K31/44 , A61K31/4402 , A61K31/4406 , A61P35/00 , C07D213/63 , C07D213/64 , C07D213/65 , C07D521/00 , A61K31/435
CPC分类号： C07D213/64 , A61K31/415 , A61K31/44 , C07D213/65 , C07D231/12 , C07D233/56 , C07D249/08
摘要： This disclosure describes compositions of matter useful as growth inhibitors of transplanted tumors in mammals: and this invention discloses a method of inducing the regression and/or palliation of various types of tumors in mammals (mammary cancer, liver cancer, skin cancer, etc.), said method comprising giving to said mammals an effective amount of a compound of the following formula: ##STR1## [wherein A represents an imidazolyl group or a pyridyl group, l represents 0 or 1, m and n each, which may be the same of different, represents an integer of 1 to 6, and, R represents a hydrogen atom or a lower alkyl group], or a salt thereof; the invention also discloses a method of inhibition (or prevention) of metastasis of the various cancers.The above formula compounds have low toxicity, and it is expected to apply various types of administration thereof such as oral administration and parenteral administration. In particular, it is expected that the compounds are useful as new type of medical (anti-cancer) compounds which can be administered orally.
摘要翻译：本公开描述了用作哺乳动物移植肿瘤生长抑制剂的物质的组合物：本发明公开了诱导哺乳动物（乳腺癌，肝癌，皮肤癌等）中各种类型肿瘤的消退和/或缓解的方法，所述方法包括给予所述哺乳动物有效量的下式化合物：其中A代表咪唑基或吡啶基，l代表0或1，m和n各自可以相同不同，表示1〜6的整数，R表示氢原子或低级烷基]或其盐; 本发明还公开了抑制（或预防）各种癌症转移的方法。上述配方化合物的毒性低，预期可以应用各种类型的给药，例如口服给药和肠胃外给药。特别地，预期这些化合物可用作可以口服给药的新型医疗（抗癌）化合物。

5. 发明授权

US08619286B2 System and method of avoiding conflicting printer job language processing 有权
标题翻译：避免打印机作业语言处理冲突的系统和方法
公开(公告)号：US08619286B2
公开(公告)日：2013-12-31
申请号：US12534535
申请日：2009-08-03
申请人： Takahiko Suzuki , Tadashi Mimura , Yuji Onozawa , Hisashi Shirakawa , Koichiro Takahashi , Kazuya Kawabata , Yoshifumi Kaneko
发明人： Takahiko Suzuki , Tadashi Mimura , Yuji Onozawa , Hisashi Shirakawa , Koichiro Takahashi , Kazuya Kawabata , Yoshifumi Kaneko
IPC分类号： G06F3/12
CPC分类号： G06F3/1205 , G06F3/1248 , G06F3/1253 , G06F3/1285
摘要： A printing control device includes: a banner data detecting unit that detects banner data from print data; a data acquiring unit that acquires, when the banner data are detected by the banner data detecting unit, data for designating a printing condition for printing a text located after the banner data in the print data; and a printing condition setting unit that sets, when the data for designating the printing condition for printing the text are acquired by the data acquiring unit, the printing condition as a printing condition for printing the print data.
摘要翻译：打印控制装置包括：横幅数据检测单元，其从打印数据检测横幅数据; 数据获取单元，当横幅数据检测单元检测到横幅数据时，获取用于指定用于打印位于打印数据中的横幅数据之后的文本的打印条件的数据; 以及打印条件设置单元，当用于指定用于打印文本的打印条件的数据被数据获取单元获取时，设置作为用于打印打印数据的打印条件的打印条件。

6. 发明申请

US20060173009A1 Agent inducing increase in bone mass 审中-公开
标题翻译：诱导骨量增加的药剂
公开(公告)号：US20060173009A1
公开(公告)日：2006-08-03
申请号：US10563107
申请日：2004-06-30
申请人： Hiroyuki Kanoh , Koichiro Takahashi , Hiromi Nara , Tatsuhiko Yamanoi , Shinji Fukushima , Ryo Naito , Susumu Igarashi
发明人： Hiroyuki Kanoh , Koichiro Takahashi , Hiromi Nara , Tatsuhiko Yamanoi , Shinji Fukushima , Ryo Naito , Susumu Igarashi
IPC分类号： A61K31/503
CPC分类号： A61K31/5025 , A61K31/662 , A61K31/663 , A61K2300/00
摘要： Osteoporosis and the like metabolic bone diseases have a high frequency of causing lumbago and the like pains and bone fracture, due to lowering of the bone strength caused by the reduction of bone mass. Accordingly, great concern has been directed toward the creation of a drug which can increase the bone mass and bone strength by controlling the whole bone metabolism. The pharmaceutical composition or combination product of the invention comprising a non-living body-derived non-peptide osteoblast differentiation promoting compound and a bisphosphonate having a bone resorption inhibitory action is useful as a bone mass increasing inducer which can increase the bone mass and/or bone strength by controlling the bone metabolism.
摘要翻译：骨质疏松等代谢性骨疾病由于骨质量下降引起的骨强度降低，频繁地引起腰痛等骨折。因此，非常关注通过控制整个骨代谢来增加骨量和骨强度的药物的产生。包含非生物体衍生的非肽成骨细胞分化促进化合物和具有骨吸收抑制作用的二膦酸盐的本发明的药物组合物或组合产品可用作骨质量增加诱导剂，其可以增加骨量和/或通过控制骨骼代谢的骨骼力量。

7. 发明授权

US06928034B2 Optical disc apparatus and method for adjusting a servo of same 有权
标题翻译：光盘装置及其调整方法
公开(公告)号：US06928034B2
公开(公告)日：2005-08-09
申请号：US10024589
申请日：2001-12-17
申请人： Hiroshi Ohtsu , Toshisada Takada , Koichiro Takahashi
发明人： Hiroshi Ohtsu , Toshisada Takada , Koichiro Takahashi
IPC分类号： G11B21/10 , G11B7/005 , G11B7/09 , G11B7/095 , G11B7/00
CPC分类号： G11B7/0908 , G11B7/0901 , G11B7/094 , G11B7/0945 , G11B7/0956
摘要： In an optical disc apparatus, a minimum jitter value is established from each jitter value measured in correspondence to a successively changed servo constant, and multiplied by a prescribed ratio so as to set a jitter threshold value. Servo constants corresponding to at least two jitter values substantially equal to the jitter threshold value is established, and an optimum servo constant is set based on this minimum of two servo constants. By doing this, it is possible to quickly and accurately detect the optimum servo constant, and achieve good servo adjustment.
摘要翻译：在光盘装置中，根据与连续变化的伺服常数相对应地测量的每个抖动值建立最小抖动值，并乘以规定的比例，以便设置抖动阈值。建立对应于基本上等于抖动阈值的至少两个抖动值的伺服常数，并且基于两个伺服常数的最小值来设定最佳伺服常数。通过这样做，可以快速，准确地检测最佳伺服常数，实现良好的伺服调整。

8. 发明授权

US5830493A Bone-forming graft 失效
标题翻译：骨形成移植物
公开(公告)号：US5830493A
公开(公告)日：1998-11-03
申请号：US817409
申请日：1997-03-25
申请人： Shoji Yokota , Seitaro Shimokawa , Ritsu Sonohara , Akira Okada , Koichiro Takahashi
发明人： Shoji Yokota , Seitaro Shimokawa , Ritsu Sonohara , Akira Okada , Koichiro Takahashi
IPC分类号： A61L27/18 , A61L27/20 , A61L27/22 , A61L27/44 , A61L27/54 , A61L27/56 , A61F2/00
CPC分类号： A61L27/44 , A61L27/18 , A61L27/20 , A61L27/22 , A61L27/54 , A61L27/56 , A61L2300/252 , A61L2300/414 , A61L2300/602 , A61L2430/02
摘要： A bone-forming graft that includes a bone morphogenetic protein (BMP) carried on a composite porous body. The composite porous body has a porous frame of a bioabsorbable hydrophilic material and a surface layer of a bioabsorbable polymer material. In particular, the present invention relates to a bone-forming graft in which the bioabsorbable hydrophilic material is one or more compounds selected from a group consisting of gelatin, hyaluronic acid, a hyaluronic acid derivative, collagen, a collagen derivative, chitosan, a chitosan derivative, and triethanolamine alginate. The bioabsorbable polymeric material is one or more compounds selected from a group consisting of a polylactic acid, a copolymer of a polylactic acid and a polyglycolic acid, and a copolymer of poly�bis(p-carboxyphenoxy)propane!anhydride and sebacic acid. The graft has excellent formability and workability and has an internal structure suitable for in vivo bone formation. Bone formation occurs not only at the periphery of the graft but also within the graft.
摘要翻译： PCT No.PCT / JP95 / 01970。 371日期1997年3月25日 102（e）1997年3月25日PCT PCT 1995年9月28日PCT公布。公开号WO96 / 10426 日期1996年4月11日一种骨形成移植物，其包括承载在复合多孔体上的骨形态发生蛋白（BMP）。复合多孔体具有生物可吸收亲水材料的多孔框架和生物可吸收聚合物材料的表面层。特别地，本发明涉及一种成骨移植物，其中生物可吸收亲水材料是一种或多种选自明胶，透明质酸，透明质酸衍生物，胶原，胶原衍生物，壳聚糖，壳聚糖衍生物和海藻酸三乙醇胺。生物可吸收聚合物材料是一种或多种选自聚乳酸，聚乳酸和聚乙醇酸的共聚物以及聚[双（对 - 羧基苯氧基）丙烷]酐和癸二酸的共聚物的化合物。移植物具有优异的成形性和可加工性，并且具有适于体内骨形成的内部结构。骨形成不仅发生在移植物的周边，而且在移植物内。

9. 发明授权

US06308382B1 Locking assembly for a metal watchband 失效
标题翻译：金属表带锁紧组件
公开(公告)号：US06308382B1
公开(公告)日：2001-10-30
申请号：US09405563
申请日：1999-09-24
申请人： Koichiro Takahashi , Kai Cheung Ho
发明人： Koichiro Takahashi , Kai Cheung Ho
IPC分类号： A44B1100
CPC分类号： A44C5/24 , Y10T24/2155 , Y10T24/2166 , Y10T24/4782
摘要： The present invention provides a clasp assembly for a metallic watch chain, mainly comprising: an inner bend plate, an outer bend plate, and a clasp cap. Said inner bend plate can fit into the narrow groove of the outer bend plate. A convex clasp is disposed on the inner bend plate and corresponds to a concave clasp disposed on the outer bend plate in shape, position and size, and the two clasps engage with each other. The lock and release of the convex and concave clasps causes the lock and release of the watch chain. The clasp cap pivotably connects with the inner bend plate through screws. The hole of the clasp cap connects with the watch chain, and the outer bend plate connects with the watch chain through the cylindrical bodies at the left end. The structure of the clasp assembly is simple and is easy to use.
摘要翻译：本发明提供了一种用于金属手表链的扣件组件，主要包括：内弯板，外弯板和扣帽。所述内弯板可以装配到外弯板的窄槽中。凸形扣具设置在内弯板上，对应于形状，位置和尺寸设置在外弯板上的凹扣，并且两扣相互啮合。凸形和凹形扣的锁定和释放导致手表链的锁定和释放。扣环通过螺丝与内弯板可枢转地连接。扣帽的孔与表链连接，外弯板通过左端的圆柱体与表链连接。扣环组合结构简单，使用方便。

10. 发明授权

US5886369A Epitaxial wafer for GaP pure green light-emitting diode and GaP pure green light-emitting diode 失效
标题翻译： GaP纯绿色发光二极管和GaP纯绿色发光二极管的外延晶片
公开(公告)号：US5886369A
公开(公告)日：1999-03-23
申请号：US965192
申请日：1997-11-06
申请人： Koichi Hasegawa , Koichiro Takahashi
发明人： Koichi Hasegawa , Koichiro Takahashi
IPC分类号： H01L21/208 , H01L33/30 , H01L33/40 , H01L27/15
CPC分类号： H01L33/30 , H01L33/0062 , H01L33/025
摘要： An epitaxial wafer for a GaP pure green light emitting diode includes an n-type single crystal GaP substrate formed in order thereon with a first n-type GaP epitaxial layer, a second n-type GaP epitaxial layer and a p-type GaP epitaxial layer. The p-type GaP epitaxial layer has a sulfur concentration of not greater than 1.times.10.sup.17 cm.sup.31 3, the second n-type GaP epitaxial layer has a carrier concentration on a side thereof interfacing with the p-type GaP epitaxial layer of 0.5-5.times.10.sup.17 cm.sup.-3, and the p-type GaP epitaxial layer has a carrier concentration on a side thereof interfacing with the second n-type GaP epitaxial layer that is 1-10.times.10.sup.17 cm.sup.-3 and is not less than twice the carrier concentration of the second n-type GaP epitaxial layer on the side thereof interfacing with the p-type GaP epitaxial layer. A GaP pure green light-emitting diode exhibiting high brightness includes the epitaxial wafer, an n-type electrode provided on a back surface of the single crystal substrate and a p-type electrode provided on the upper surface of the p-type GaP epitaxial layer.
摘要翻译：用于GaP纯绿色发光二极管的外延晶片包括依次形成有第一n型GaP外延层，第二n型GaP外延层和p型GaP外延层的n型单晶GaP衬底。 p型GaP外延层的硫浓度不大于1×10 17 cm -3 3 3，第二n型GaP外延层在其与p型GaP外延层接合的一侧上具有0.5-5×10 17 cm -1的GaP外延层， 3，并且p型GaP外延层在其与第二n型GaP外延层接合的一侧上的载流子浓度为1-10×10 17 cm -3，并且不小于第二n-型GaP外延层的载流子浓度的两倍， GaP外延层与p型GaP外延层接合。显示高亮度的GaP纯绿色发光二极管包括外延晶片，设置在单晶衬底的背面上的n型电极和设置在p型GaP外延层的上表面上的p型电极。

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