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1. 发明授权

US5877233A Denture adhesive compositions 失效
标题翻译：假牙粘合剂组合物
公开(公告)号：US5877233A
公开(公告)日：1999-03-02
申请号：US824940
申请日：1997-03-27
申请人： Nong Liang , Jayanth Rajaiah , Kimberly Ann Gilday-Weber
发明人： Nong Liang , Jayanth Rajaiah , Kimberly Ann Gilday-Weber
IPC分类号： A61K6/00
CPC分类号： A61K6/0026 , Y10T428/2891
摘要： Disclosed is a denture adhesive composition comprising at least one non-adhesive self-supporting layer; and a partial salt of a lower alkyl vinyl ether-maleic acid copolymer wherein the partial salt comprises a cationic salt function consisting essentially of: from about 0.01% to about 10% of ferric iron cations; and from about 0.1% to about 75% of divalent and/or monovalent metal cations selected from the group consisting of zinc, calcium, magnesium, potassium, sodium, ammonium, and mixtures thereof.
摘要翻译：公开了一种义齿粘合剂组合物，其包含至少一个非粘性自支撑层; 和低级烷基乙烯基醚 - 马来酸共聚物的部分盐，其中所述部分盐包含基本上由以下组成的阳离子盐功能：约0.01％至约10％的三价铁阳离子; 和约0.1％至约75％的选自锌，钙，镁，钾，钠，铵及其混合物的二价和/或一价金属阳离子。

2. 发明授权

US5872160A Denture stabilizing compositions 失效
标题翻译：义齿稳定组合物
公开(公告)号：US5872160A
公开(公告)日：1999-02-16
申请号：US835040
申请日：1997-03-27
申请人： Nong Liang , Jayanth Rajaiah , Kimberly Ann Gilday-Weber
发明人： Nong Liang , Jayanth Rajaiah , Kimberly Ann Gilday-Weber
IPC分类号： A61K6/00 , A61C13/23 , C09J7/00
CPC分类号： A61K6/0026
摘要： Disclosed is a denture adhesive composition comprising at least one non-adhesive self-supporting layer; and a partial salt of a lower alkyl vinyl ether-maleic acid copolymer, the partial salt copolymer comprising carboxyl groups, of which from about 50% to about 95% are neutralized by one or more metal cations; wherein the partial salt copolymer is covalently crosslinked with an organic crosslinker and wherein the molar ratio of organic crosslinker to carboxyl groups, prior to neutralization by the metal cations, is from about 0.1% to about 30%.
摘要翻译：公开了一种义齿粘合剂组合物，其包含至少一个非粘性自支撑层; 和低级烷基乙烯基醚 - 马来酸共聚物的部分盐，包含羧基的部分盐共聚物，其中约50％至约95％被一种或多种金属阳离子中和; 其中所述部分盐共聚物与有机交联剂共价交联，并且其中在被金属阳离子中和之前，有机交联剂与羧基的摩尔比为约0.1％至约30％。

3. 发明授权

US06617374B1 Denture adhesives with mixed salts of alkyl vinyl ether-maleic copolymer or terpolymer 有权
标题翻译：具有烷基乙烯基醚 - 马来酸共聚物或三元共聚物的混合盐的假牙粘合剂
公开(公告)号：US06617374B1
公开(公告)日：2003-09-09
申请号：US09389209
申请日：1999-09-02
申请人： Jayanth Rajaiah , Carole Ann Schumacher , John Roy Whitney , Kimberly Ann Gilday-Weber , Robert Hargitt Culbertson
发明人： Jayanth Rajaiah , Carole Ann Schumacher , John Roy Whitney , Kimberly Ann Gilday-Weber , Robert Hargitt Culbertson
IPC分类号： A61C1323
CPC分类号： A61K6/0026 , C08F8/44 , C08L35/08 , C08L1/28 , C08L89/04 , C08L5/04 , C08L5/08 , C08L71/02 , C08L33/26 , C08L33/08 , C08L29/04 , C08L83/04 , C08L39/06
摘要： The present invention relates to a denture adhesive composition comprising mixed salts of an alkyl vinyl ether-maleic acid or anhydride copolymer and/or terpolymer with isobutylene wherein the mixed salt contains a cationic salt function comprising at least about 22.5% calcium cations, from about 15% to about 25% of zinc cations, of the total initial carboxyl groups reacted, the mixed salt containing from about 36% to about 50% free acid component. In addition the present invention relates to denture adhesive compositions comprising the above composition and at least one non-adhesive self-supporting layer. The present invention further relates to a method of increasing the adhesion of dentures to the oral cavity by applying the above compositions to dentures, directly to the oral cavity, palate or ridge of the oral cavity, or applying it to both, and thereafter securing the denture to the ridge or palate of the oral cavity.
摘要翻译：本发明涉及一种义齿粘合剂组合物，其包含烷基乙烯基醚 - 马来酸酐或酸酐共聚物和/或三元共聚物与异丁烯的混合盐，其中混合盐含有阳离子盐功能，其包含至少约22.5％的钙阳离子，约15 约25％的锌阳离子，总的初始羧基反应，混合盐含有约36％至约50％的游离酸组分。此外，本发明涉及包含上述组合物和至少一种非粘性自支撑层的义齿粘合剂组合物。本发明还涉及一种通过将上述组合物直接应用到口腔的口腔，口腔或脊部或将其应用于两者的方法，从而将义齿增加到口腔的粘附力，然后将义齿到口腔的脊或腭。

4. 发明授权

US06355706B1 Denture adhesives with mixed salt copolymers of terpolymers 有权
标题翻译：具有三元共聚物混合盐共聚物的义齿粘合剂
公开(公告)号：US06355706B1
公开(公告)日：2002-03-12
申请号：US09537380
申请日：2000-03-29
申请人： Jayanth Rajaiah , Carole Ann Schumacher , John Roy Whitney , Kimberly Ann Gilday-Weber , Lisa Catron Ernst
发明人： Jayanth Rajaiah , Carole Ann Schumacher , John Roy Whitney , Kimberly Ann Gilday-Weber , Lisa Catron Ernst
IPC分类号： A61K600
CPC分类号： C08F8/44 , A61K6/0026 , C08L35/08
摘要： The present invention relates to a denture adhesive composition comprising mixed salts of an alkyl vinyl ether-maleic acid copolymer wherein the mixed salt contains a cationic salt function comprising from about 5% to about 50% zinc cations; from 0% to about 2.5% of a cation selected from the group consisting of iron, boron, aluminum, vanadium, chromium, manganese, nickel, copper, yttrium, titanium, and mixtures thereof; from about 30% to about 60% free acid component; an effective adhesive amount of magnesium cations; and an effective adhesive amount of a cation selected from the group consisting of calcium, strontium, and mixtures thereof; wherein the total level of magnesium, calcium and strontium is from about 5% to about 65%. In addition the present invention relates to denture adhesive compositions comprising the above composition and at least one non-adhesive self-supporting layer. The present invention further relates to a method of increasing the adhesion of dentures to the oral cavity by applying the above compositions to dentures, directly to the oral cavity, palate or ridge of the oral cavity, or applying it to both, and thereafter securing the dentures to the ridge or palate of the oral cavity.
摘要翻译：本发明涉及包含烷基乙烯基醚 - 马来酸共聚物的混合盐的义齿粘合剂组合物，其中混合盐含有包含约5％至约50％锌阳离子的阳离子盐功能; 0％至约2.5％的选自铁，硼，铝，钒，铬，锰，镍，铜，钇，钛及其混合物的阳离子; 约30％至约60％的游离酸组分; 有效粘合量的镁阳离子; 和有效粘合量的选自钙，锶及其混合物的阳离子; 其中镁，钙和锶的总含量为约5％至约65％。此外，本发明涉及包含上述组合物和至少一种非粘性自支撑层的义齿粘合剂组合物。本发明还涉及一种通过将上述组合物直接应用到口腔的口腔，口腔或脊部或将其应用于两者的方法，从而将义齿增加到口腔的粘附力，然后将假牙到口腔的脊或腭。

5. 发明授权

US06677391B1 Tartar control denture adhesive compositions 有权
标题翻译：鞑靼控制义齿粘合剂组合物
公开(公告)号：US06677391B1
公开(公告)日：2004-01-13
申请号：US09716810
申请日：2000-11-20
申请人： Jayanth Rajaiah , Kimberly Ann Gilday-Weber , Lisa Catron Ernst , William Michael Glandorf , Donald James White, Jr.
发明人： Jayanth Rajaiah , Kimberly Ann Gilday-Weber , Lisa Catron Ernst , William Michael Glandorf , Donald James White, Jr.
IPC分类号： A61K608
CPC分类号： A61K6/097 , A61K6/0026 , Y10T442/3854 , Y10T442/3886 , Y10T442/3894 , Y10T442/3959 , C08L1/284 , C08L5/04 , C08L29/04 , C08L1/286 , C08L35/00 , C08L39/06 , C08L25/08 , C08L33/26 , C08L33/08 , C08L79/00 , C08L67/02 , C08L5/08
摘要： The present invention relates to a non-aqueous denture adhesive composition comprising a safe and effective adhesive amount of a denture adhesive; a safe and effective amount of an anticalculus agent; and a non-aqueous denture adhesive carrier; wherein the anticalculus agent is a material effective in reducing calcium phosphate mineral deposition related to calculus formation. The present invention further relates to a method of delivering an anticalculus agent to the oral cavity and teeth, by applying the above composition to dentures, directly to the oral cavity, or applying it to both, and thereafter securing the dentures to the oral cavity.
摘要翻译：本发明涉及一种非水性义齿粘合剂组合物，其包含安全有效的粘合剂量的义齿粘合剂; 安全有效量的抗牙垢剂; 和非水性义齿粘合剂载体; 其中所述防牙垢剂是有效减少与结石形成相关的磷酸钙矿物沉积的材料。本发明还涉及通过将上述组合物直接应用于口腔或将其施用于口腔，然后将义齿固定到口腔上，将抗牙垢剂递送至口腔和牙齿的方法。

6. 发明授权

US06475498B1 Method to inhibit tartar and stain using denture adhesive compositions 有权
标题翻译：使用义齿粘合剂组合物抑制牙垢和染色的方法
公开(公告)号：US06475498B1
公开(公告)日：2002-11-05
申请号：US09716820
申请日：2000-11-20
申请人： Jayanth Rajaiah , Kimberly Ann Gilday-Weber , Lisa Catron Ernst , Larry Gregory Martin , Marjorie Samuel Becus , Timothy Sadley Owens , Ann Maria Case
发明人： Jayanth Rajaiah , Kimberly Ann Gilday-Weber , Lisa Catron Ernst , Larry Gregory Martin , Marjorie Samuel Becus , Timothy Sadley Owens , Ann Maria Case
IPC分类号： A61K608
CPC分类号： A61K6/0026 , A61K6/0058 , C08L35/08 , C08L33/08 , C08L1/08 , C08L89/04 , C08L5/04 , C08L71/02 , C08L33/26 , C08L29/04 , C08L39/06 , C08L1/28 , C08L93/02 , C08L23/12 , C08L1/12
摘要： The present invention relates to a method of reducing, controlling, inhibiting, preventing, protecting against, or minimizing calculus, tartar, plaque, or stain, in the oral cavity, by applying a denture adhesive composition to the oral cavity, the denture adhesive composition comprising: (a) a safe and effective adhesive amount of a denture adhesive component; and (b) a safe and effective amount of a non-aqueous denture adhesive carrier.
摘要翻译：本发明涉及通过将义齿粘合剂组合物施用于口腔来减少，控制，抑制，预防，防止或最小化口腔中牙垢，牙垢，斑块或染色的方法，义齿粘合剂组合物包括：（a）安全有效的粘合剂量的义齿粘合剂组分; 和（b）安全有效量的非水性义齿粘合剂载体。

7. 发明授权

US06905672B2 Compositions and methods to inhibit tartar and microbes using denture adhesive compositions with colorants 有权
标题翻译：使用具有着色剂的义齿粘合剂组合物抑制牙垢和微生物的组合物和方法
公开(公告)号：US06905672B2
公开(公告)日：2005-06-14
申请号：US10218632
申请日：2002-08-14
申请人： Jayanth Rajaiah , Kimberly Ann Gilday-Weber , Lisa Catron Ernst , Timothy Sadley Owens , John E. Barnes , Nivedita Ramji
发明人： Jayanth Rajaiah , Kimberly Ann Gilday-Weber , Lisa Catron Ernst , Timothy Sadley Owens , John E. Barnes , Nivedita Ramji
IPC分类号： A61K6/00 , A61K7/16 , A61C13/225
CPC分类号： A61K6/0026 , A61K6/0058 , C08L35/08 , C08L3/00 , C08L1/08 , C08L89/04 , C08L5/04 , C08L5/08 , C08L71/02 , C08L33/26 , C08L29/04 , C08L39/06 , C08L1/28 , C08L93/02 , C08L91/06
摘要： The present invention relates to compositions comprising: (a) from about 15% to about 70% by weight of the composition of a denture adhesive component; (b) a safe and effective amount of a colorant selected from the group consisting of xanthene dyes, fluorescein dyes, free acids and salts thereof, and mixtures thereof; and (c) a safe and effective amount of a non-aqueous denture adhesive carrier. The present invention further relates to a method of reducing, inhibiting and/or preventing, calculus, tartar, plaque, stain, and/or microbes in the oral cavity, by applying the above denture adhesive composition to the oral cavity of a denture wearer in need thereof. The present invention further relates to a method of providing improved antimicrobial effects in the oral cavity by applying the above denture adhesive composition to the oral cavity of a denture wearer in need thereof.
摘要翻译：本发明涉及组合物，其包含：（a）组合物的约15％至约70％重量的义齿粘合剂组分; （b）安全有效量的选自呫吨染料，荧光素染料，游离酸及其盐及其混合物的着色剂; 和（c）安全有效量的非水性义齿粘合剂载体。本发明还涉及通过将上述义齿粘合剂组合物应用于假牙佩戴者的口腔中来减少，抑制和/或预防口腔中的结石，牙垢，斑块，斑点和/或微生物的方法需要。本发明还涉及通过将上述义齿粘合剂组合物应用于有需要的义齿穿着者的口腔而在口腔中提供改善的抗微生物作用的方法。

8. 发明授权

US07008976B2 Denture adhesive compositions 有权
公开(公告)号：US07008976B2
公开(公告)日：2006-03-07
申请号：US10219002
申请日：2002-08-14
申请人： Jayanth Rajaiah , Carole Ann Schumacher , John Roy Whitney , Kimberly Ann Gilday-Weber , Edward Dewey Smith, III
发明人： Jayanth Rajaiah , Carole Ann Schumacher , John Roy Whitney , Kimberly Ann Gilday-Weber , Edward Dewey Smith, III
IPC分类号： C08K3/08
CPC分类号： A61Q11/02 , A61K6/0026 , A61K8/19 , A61K8/27 , C08F8/44 , C08L35/08 , C08L1/08 , C08L3/00 , C08L1/28 , C08L67/00 , C08L23/12 , C08L77/10 , C08L1/12
摘要： The present invention relates to a denture adhesive composition comprising mixed salts of an alkyl vinyl ether-maleic acid or anhydride copolymer and/or terpolymer with isobutylene wherein the mixed salt contains a cationic salt function comprising at least about 1% strontium cations, from about 1% to about 40% of zinc cations, from 0% to about 2.5% of a cation selected from the group consisting of iron, boron, aluminum, vanadium, chromium, manganese, nickel, copper, yttrium, titanium, and mixtures thereof; from about 36% to about 60% free acid component; and from 0% to about 65% of a cation selected from the group consisting of magnesium, calcium, and mixtures thereof. In addition, the present invention relates to denture adhesive compositions comprising the above composition and at least one non-adhesive self-supporting layer. The present invention further relates to a method of increasing the adhesion of dentures to the oral cavity by applying the above compositions to dentures, directly to the oral cavity, palate or ridge of the oral cavity, or applying it to both, and thereafter securing the dentures to the ridge or palate of the oral cavity.

9. 发明授权

US06706781B2 Denture adhesive compositions with antimicrobial agents 有权
标题翻译：具有抗菌剂的假牙粘合剂组合物
公开(公告)号：US06706781B2
公开(公告)日：2004-03-16
申请号：US10218651
申请日：2002-08-14
申请人： Jayanth Rajaiah , Kimberly Ann Gilday-Weber , Lisa Catron Ernst , Thinh Nguyen Ha , John E. Barnes , Nivedita Ramji , Ann Maria Kneipp
发明人： Jayanth Rajaiah , Kimberly Ann Gilday-Weber , Lisa Catron Ernst , Thinh Nguyen Ha , John E. Barnes , Nivedita Ramji , Ann Maria Kneipp
IPC分类号： A61K600
CPC分类号： A61K6/0026 , C08L35/08 , C08L1/28
摘要： The present invention relates to methods and compositions for reducing, inhibiting, and/or preventing, calculus, tartar, plaque, and/or microbes, in the oral cavity, comprising from about 15% to about 70% of an alkyl vinyl ether maleic copolymer or terpolymer denture adhesive component, an effective amount of a quaternary ammonium antimicrobial agent selected from the group consisting of cetylpyridinium chloride, domiphen bromide, and mixtures thereof, and a non-aqueous vehicle. A denture wearer in need thereof applies the composition to the oral cavity and/or the denture prosthesis and thereafter secures the denture to the oral cavity.
摘要翻译：本发明涉及在口腔中减少，抑制和/或预防结石，牙垢，斑块和/或微生物的方法和组合物，其包含约15％至约70％的烷基乙烯基醚马来酸共聚物或三元共聚物义齿粘合剂组分，有效量的选自氯化十六烷基吡啶，溴化三苯胺及其混合物的季铵抗微生物剂和非水性载体。有需要的义齿穿着者将组合物施用于口腔和/或假牙假体，然后将义齿固定到口腔。

10. 发明授权

US06475497B1 Tartar control denture adhesive compositions 有权
标题翻译：鞑靼控制义齿粘合剂组合物
公开(公告)号：US06475497B1
公开(公告)日：2002-11-05
申请号：US09716766
申请日：2000-11-20
申请人： Jayanth Rajaiah , Kimberly Ann Gilday-Weber , Lisa Catron Ernst
发明人： Jayanth Rajaiah , Kimberly Ann Gilday-Weber , Lisa Catron Ernst
IPC分类号： C08F844
CPC分类号： A61K6/0026 , C08L35/08 , C08L33/08 , C08L3/00 , C08L1/08 , C08L89/04 , C08L5/04 , C08L5/08 , C08L71/02 , C08L33/26 , C08L29/04 , C08L39/06 , C08L1/28 , C08L31/04 , C08L83/04
摘要： The present invention relates to a non-aqueous denture adhesive composition comprising a safe and effective adhesive amount of a denture adhesive; a safe and effective amount of an anticalculus agent; and a non-aqueous denture adhesive carrier; wherein the anticalculus agent is a material effective in reducing calcium phosphate mineral deposition related to calculus formation. The present invention further relates to a method of delivering an anticalculus agent to the oral cavity and teeth, by applying the above composition to dentures, directly to the oral cavity, or applying it to both, and thereafter securing the dentures to the oral cavity.
摘要翻译：本发明涉及一种非水性义齿粘合剂组合物，其包含安全有效的粘合剂量的义齿粘合剂; 安全有效量的抗牙垢剂; 和非水性义齿粘合剂载体; 其中所述防牙垢剂是有效减少与结石形成相关的磷酸钙矿物沉积的材料。本发明还涉及通过将上述组合物直接施用于口腔或将其施用于口腔，然后将义齿固定到口腔上，将抗牙垢剂递送至口腔和牙齿的方法。

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