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1. 外观设计

USD652821S1 Headphone 有权
公开(公告)号：USD652821S1
公开(公告)日：2012-01-24
申请号：US29382413
申请日：2011-01-03
申请人： Noel Lee , Jacky Hsiung , David Leung , Einstein Galang
设计人： Noel Lee , Jacky Hsiung , David Leung , Einstein Galang

2. 发明申请

US20140051279A1 Posable Strain Relief for a Cable 有权
标题翻译：电缆应力消除
公开(公告)号：US20140051279A1
公开(公告)日：2014-02-20
申请号：US13587860
申请日：2012-08-16
申请人： Noel Lee , Kendrew Lee , Jacky Hsiung , David Leung
发明人： Noel Lee , Kendrew Lee , Jacky Hsiung , David Leung
IPC分类号： H01R13/56
CPC分类号： H01R13/562 , H01R13/567 , H01R13/5833 , H01R13/5841
摘要： A possible strain relief for use with a cable which can he bent into a particular shape by the user, and which retains that shape, thus allowing modification to suit a specific environment or use.
摘要翻译：用于电缆的可能的应变消除，其可以由使用者弯曲成特定形状，并且保持该形状，从而允许修改以适应特定环境或使用。

3. 发明授权

US08974242B2 Posable strain relief for a cable 有权
标题翻译：电缆的可变应变消除
公开(公告)号：US08974242B2
公开(公告)日：2015-03-10
申请号：US13587860
申请日：2012-08-16
申请人： Noel Lee , Kendrew Lee , Jacky Hsiung , David Leung
发明人： Noel Lee , Kendrew Lee , Jacky Hsiung , David Leung
IPC分类号： H01R13/52 , H01R13/56 , H01R13/58
CPC分类号： H01R13/562 , H01R13/567 , H01R13/5833 , H01R13/5841
摘要： A posable strain relief for use with a cable which can he bent into a particular shape by the user, and which retains that shape, thus allowing modification to suit a specific environment or use.
摘要翻译：一种与电缆一起使用的可伸缩应变消除装置，其可以由用户弯曲成特定的形状，并且保持该形状，从而允许修改以适应特定环境或使用。

4. 发明申请

US20130114816A1 Audio Coupling System 审中-公开
标题翻译：音频耦合系统
公开(公告)号：US20130114816A1
公开(公告)日：2013-05-09
申请号：US13640299
申请日：2011-01-03
申请人： Noel Lee , David Leung
发明人： Noel Lee , David Leung
IPC分类号： H04R1/10 , H04R5/04
CPC分类号： H04R1/1033 , H04R1/1091 , H04R5/04 , H04R2420/09
摘要： A device for the sharing audio signals. A pair of headphones includes circuitry for connecting to an audio signal input, as is typical, but also for connecting to an audio signal output. The audio output allows a plurality of personal listening devices, for example headphones, to be linked together allowing a plurality of listeners to listen to the same audio signal, yet maintain the utility provided by a headphone listening system
摘要翻译：用于共享音频信号的设备。一对耳机包括用于连接到音频信号输入的电路，如典型的，但也用于连接到音频信号输出。音频输出允许将多个个人聆听装置（例如耳机）连接在一起，允许多个收听者收听相同的音频信号，同时保持由耳机收听系统提供的效用

5. 发明申请

US20120269374A1 AUTOMATICALLY ADJUSTING HEADPHONES 审中-公开
标题翻译：自动调节耳机
公开(公告)号：US20120269374A1
公开(公告)日：2012-10-25
申请号：US13332113
申请日：2011-12-20
申请人： Noel Lee , David Leung
发明人： Noel Lee , David Leung
IPC分类号： H04R1/10
CPC分类号： H04R1/1008
摘要： This invention provides continuously adjustable headphones that utilize a ball and socket hinge arrangement that allows the ear cup shell portion of the headphone to rotate in any direction, allowing the speaker housing to articulate about the ball joint in any directional plane to provide comfort and superior acoustic performance.
摘要翻译：本发明提供连续可调节的耳机，其使用允许耳机的耳罩壳部分在任何方向上旋转的球窝铰链装置，允许扬声器壳体在任何方向平面上围绕球接头铰接以提供舒适性和优异的声学性能。

6. 发明申请

US20110051979A1 Headphone Ear Tips with Sound Conduit Mounting Structure 审中-公开
标题翻译：耳机耳塞与声管安装结构
公开(公告)号：US20110051979A1
公开(公告)日：2011-03-03
申请号：US12651943
申请日：2010-01-04
申请人： Noel Lee , David Leung
发明人： Noel Lee , David Leung
IPC分类号： H04R25/00 , H04R1/10
CPC分类号： H04R1/1016 , H04R1/1083
摘要： An ear tip comprised of two or more contiguous materials, in combination with sound conduit structure comprised of one or more rigid materials, wherein the ear tip mounts upon said sound conduit structure.
摘要翻译：由两个或更多个连续材料组成的耳塞，与由一个或多个刚性材料组成的声音导管结构组合，其中耳塞安装在所述声音导管结构上。

7. 发明授权

US08748577B2 Conjugates of biologically active polypeptides having an increased in vivo half-life 失效
标题翻译：具有增加的体内半衰期的生物活性多肽的缀合物
公开(公告)号：US08748577B2
公开(公告)日：2014-06-10
申请号：US13363278
申请日：2012-01-31
申请人： Marc Besman , Stewart Chipman , David Leung , Jack Singer
发明人： Marc Besman , Stewart Chipman , David Leung , Jack Singer
IPC分类号： C07K14/00 , A61K38/16 , A61K38/14
CPC分类号： C07K14/47 , A61K38/00 , Y02A50/409 , Y02A50/473
摘要： Disclosed are biologically active protein conjugates that comprise a biologically active polypeptide coupled via a peptide bond to a polypeptide comprising from 2 to about 500 units of a repeating peptide motif, wherein the biologically active protein conjugate exhibits a modified plasma half-life compared to the intrinsic half-life of the unconjugated biologically active polypeptide or protein. Also disclosed are methods of making and using the conjugated proteins, as well as methods for determining whether a given conjugate exhibits a modified half life relative to the intrinsic half life of the unconjugated polypeptide.
摘要翻译：公开了生物活性蛋白质缀合物，其包含通过肽键与多肽偶联的生物活性多肽，所述多肽包含2至约500个单位的重复肽基序，其中所述生物活性蛋白质缀合物与内在的未缀合的生物活性多肽或蛋白质的半衰期。还公开了制备和使用共轭蛋白的方法，以及用于确定给定缀合物相对于未缀合多肽的固有半衰期显示修饰的半衰期的方法。

8. 发明申请

US20090298762A1 CONJUGATES OF BIOLOGICALLY ACTIVE PROTEINS HAVING A MODIFIED IN VIVO HALF-LIFE 有权
标题翻译：生物活性蛋白质与血液中的生物活性蛋白的结合
公开(公告)号：US20090298762A1
公开(公告)日：2009-12-03
申请号：US12251324
申请日：2008-10-14
申请人： Marc Besman , Stewart Chipman , David Leung , Jack Singer
发明人： Marc Besman , Stewart Chipman , David Leung , Jack Singer
IPC分类号： A61K38/16 , C07K14/745 , C07K14/61 , C07K14/54 , C07K14/52 , C07K16/18 , C07K14/00 , C07K7/08 , C07K7/06 , C07K7/00 , C07K5/00 , C12N9/50 , C12N9/00 , C07K14/555 , C07K14/575 , A61K38/10 , A61K38/08 , A61K38/07 , A61K38/06 , A61K38/05 , C07H21/00 , C12N15/74 , C12N5/06 , C12N1/21 , C12N1/16 , C12P21/02 , G01N33/48 , A61P43/00
CPC分类号： C07K14/47 , A61K38/00 , Y02A50/409 , Y02A50/473
摘要： Disclosed are biologically active protein conjugates that comprise a biologically active polypeptide coupled via a peptide bond to a polypeptide comprising from 2 to about 500 units of a repeating peptide motif, wherein the biologically active protein conjugate exhibits a modified plasma half-life compared to the intrinsic half-life of the unconjugated biologically active polypeptide or protein. Also disclosed are methods of making and using the conjugated proteins, as well as methods for determining whether a given conjugate exhibits a modified half life relative to the intrinsic half life of the unconjugated polypeptide.
摘要翻译：公开了生物活性蛋白质缀合物，其包含通过肽键与多肽偶联的生物活性多肽，所述多肽包含2至约500个单位的重复肽基序，其中所述生物活性蛋白质缀合物与内在的未缀合的生物活性多肽或蛋白质的半衰期。还公开了制备和使用共轭蛋白的方法，以及用于确定给定缀合物相对于未缀合多肽的固有半衰期显示修饰的半衰期的方法。

9. 发明授权

US6111397A Temperature-compensated reference voltage generator and method therefor 失效
标题翻译：温度补偿参考电压发生器及其方法
公开(公告)号：US6111397A
公开(公告)日：2000-08-29
申请号：US120622
申请日：1998-07-22
申请人： David Leung
发明人： David Leung
IPC分类号： G05F3/24 , G05F3/26 , G05F3/16
CPC分类号： G05F3/245 , G05F3/262 , Y10S323/907
摘要： A reference voltage generator for producing a regulated, temperature-compensated output voltage from an unregulated power supply voltage is provided herein. The reference voltage generator includes a pre-regulating circuit and a temperature-compensating circuit. The temperature compensating circuit includes a first series path comprising a first cascode current sources and a first resistor; a second series path comprising a second cascode current source, a first field effect transistor and a first diode; and a third series path comprising a third cascode current source, a second field effect transistor, a second resistor and a second diode. The first series path being connected to the second series path between the first field resistor and the first diode. The current produced by the first current source, develops a voltage across the first resistor, which varies at least as a function of the ratio of the first and second resistors, the ratio of the diode junction areas, the dimensions of the first and second field effect transistors, and the first diode thermal voltage which has a positive temperature coefficient. The voltage across the first diode has a negative temperature coefficient. The output voltage taken across both the first resistor and first diode can be made substantially temperature invariant if the resistor ratio is selected such that it amplifies the temperature coefficient of the thermal voltage so that it is substantially equal and opposite to the temperature coefficient of the first diode voltage.
摘要翻译：本文提供了一种用于从未调节的电源电压产生调节温度补偿的输出电压的参考电压发生器。参考电压发生器包括预调节电路和温度补偿电路。温度补偿电路包括第一串联路径，其包括第一共源共栅电流源和第一电阻器; 第二串联路径，包括第二共源共栅电流源，第一场效应晶体管和第一二极管; 以及包括第三共源共栅电流源，第二场效应晶体管，第二电阻和第二二极管的第三串联路径。第一串联路径连接到第一场电阻器和第一二极管之间的第二串联路径。由第一电流源产生的电流产生跨越第一电阻器的电压，其至少与第一和第二电阻器的比率，二极管接合面积的比率，第一和第二场域的尺寸，效应晶体管，以及具有正温度系数的第一二极管热电压。第一二极管两端的电压具有负温度系数。如果选择电阻比使得其放大热电压的温度系数使得其基本上等于并与第一电阻和第一二极管的温度系数相反，则可以使第一电阻器和第一二极管两端的输出电压基本上是温度不变的二极管电压。

10. 发明授权

US08129348B2 Conjugates of biologically active proteins having a modified in vivo half-life 有权
标题翻译：具有改变的体内半衰期的生物活性蛋白质的缀合物
公开(公告)号：US08129348B2
公开(公告)日：2012-03-06
申请号：US12251324
申请日：2008-10-14
申请人： Marc Besman , Stewart Chipman , David Leung , Jack Singer
发明人： Marc Besman , Stewart Chipman , David Leung , Jack Singer
IPC分类号： A61K38/16 , A61K38/14 , C07K14/00
CPC分类号： C07K14/47 , A61K38/00 , Y02A50/409 , Y02A50/473
摘要： Disclosed are biologically active protein conjugates that comprise a biologically active polypeptide coupled via a peptide bond to a polypeptide comprising from 2 to about 500 units of a repeating peptide motif, wherein the biologically active protein conjugate exhibits a modified plasma half-life compared to the intrinsic half-life of the unconjugated biologically active polypeptide or protein. Also disclosed are methods of making and using the conjugated proteins, as well as methods for determining whether a given conjugate exhibits a modified half life relative to the intrinsic half life of the unconjugated polypeptide.
摘要翻译：公开了生物活性蛋白质缀合物，其包含通过肽键与多肽偶联的生物活性多肽，所述多肽包含2至约500个单位的重复肽基序，其中所述生物活性蛋白质缀合物与内在的未缀合的生物活性多肽或蛋白质的半衰期。还公开了制备和使用共轭蛋白的方法，以及用于确定给定缀合物相对于未缀合多肽的固有半衰期显示修饰的半衰期的方法。

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