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1. 发明授权

US06277964B1 Anti-PAH monoclonal antibodies and cell lines producing the same 有权
标题翻译：抗PAH单克隆抗体和产生相同的细胞系
公开(公告)号：US06277964B1
公开(公告)日：2001-08-21
申请号：US09265872
申请日：1999-03-11
申请人： Nobuhiko Yamashita , Kazunobu Miura , Naoya Ichimura , Chiwa Kataoka , Junko Sakaki , Yutaka Ohtani , Hirohisa Kitagawa
发明人： Nobuhiko Yamashita , Kazunobu Miura , Naoya Ichimura , Chiwa Kataoka , Junko Sakaki , Yutaka Ohtani , Hirohisa Kitagawa
IPC分类号： C07K1644
CPC分类号： C07K16/44 , G01N33/5308 , Y10S530/808 , Y10S530/809
摘要： The present invention provides monoclonal antibodies suitable for monitoring polycyclic aromatic hydrocarbons (PAHs) by an immunoasay, hybridoma cell lines producing said antibodies, and an immunoassay for analyzing PAHs in a sample using said monoclonal antibodies. In addition, the present invention provides PAH conjugates useful as an immunogen in preparing said antibodies and as a standard substance in a competitive assay.
摘要翻译：本发明提供了适用于通过免疫测定监测多环芳烃（PAH）的单克隆抗体，产生所述抗体的杂交瘤细胞系以及使用所述单克隆抗体分析样品中PAH的免疫测定法。此外，本发明提供了在竞争性测定中用作制备所述抗体和作为标准物质的免疫原的PAH缀合物。

2. 发明授权

US07591200B2 Method of detecting high-concentration region direction of pollutant in soil 失效
标题翻译：检测土壤中高浓度区域污染物方向的方法
公开(公告)号：US07591200B2
公开(公告)日：2009-09-22
申请号：US11255938
申请日：2005-10-24
申请人： Yasuo Takahashi , Shigekazu Shimizu , Naoya Ichimura , Yasuhisa Fujii , Tokugen Yasuda
发明人： Yasuo Takahashi , Shigekazu Shimizu , Naoya Ichimura , Yasuhisa Fujii , Tokugen Yasuda
IPC分类号： G01N15/08
CPC分类号： G01N33/24
摘要： A recovery phenomenon in which the concentration of a compound to be measured in soil increases again after reducing the concentration is utilized for changing the distribution state of the compound to be measured in soil, whereby the direction of the high-concentration region of the compound to be measured in soil can be detected.
摘要翻译：减少浓度后土壤中待测量化合物浓度再次升高的恢复现象用于改变土壤中待测化合物的分布状态，由此化合物的高浓度区域的方向为在土壤中测量可以检测。

3. 发明申请

US20130250395A1 COLOR TUNABLE SUBSTRATE 有权
标题翻译：彩色底座
公开(公告)号：US20130250395A1
公开(公告)日：2013-09-26
申请号：US13704329
申请日：2012-03-26
申请人： Naoya Ichimura
发明人： Naoya Ichimura
IPC分类号： G02F1/11
CPC分类号： G02F1/11 , G02B5/285 , G02B26/001 , G02F1/0131 , G02F1/21
摘要： A color tunable substrate is disclosed. The color tunable substrate includes multiple layers. A color of the color tunable substrate can be tuned by altering or adjusting characteristics of the layers included in the color tunable substrate.
摘要翻译：公开了一种颜色可调衬底。颜色可调衬底包括多层。可以通过改变或调整包括在颜色可调衬底中的层的特性来调整颜色可调衬底的颜色。

4. 发明申请

US20100137155A1 BIOSENSOR, METHOD FOR FABRICATING THE SAME, DETECTING METHOD UTILIZING THE SAME 审中-公开
标题翻译：生物传感器，其制造方法，使用该方法的检测方法
公开(公告)号：US20100137155A1
公开(公告)日：2010-06-03
申请号：US12376712
申请日：2007-08-02
申请人： Yoshiroh Akagi , Kazuo Ban , Kyoko Seo , Naoya Ichimura , Atsushi Mizusawa
发明人： Yoshiroh Akagi , Kazuo Ban , Kyoko Seo , Naoya Ichimura , Atsushi Mizusawa
IPC分类号： C40B30/04 , C40B40/10 , C40B50/14
CPC分类号： G01N33/54353
摘要： A biosensor capable of highly sensitive detection of a recognition target substance while having structural stability is provided at low cost. The biosensor is for capturing and detecting a recognition target substance and includes a linker made of a hydrocarbon compound having two or more particular functional groups, a peptide serving as a molecular recognition substance directly bonded to one particular functional group of the linker, and a support directly bonded to the other particular functional group of the linker. Preferably, the particular functional groups each are a reaction product functional group of an epoxy group and an amino group. The peptide is an artificially synthesized peptide including three or more consecutive amino acid sequences, among amino acid sequences of a natural immunoglobulin, that exist in a part corresponding to a hypervariable area of the natural immunoglobulin.
摘要翻译：以低成本提供能够高度敏感地检测识别目标物质同时具有结构稳定性的生物传感器。生物传感器用于捕获和检测识别目标物质，并且包括由具有两个或更多个特定官能团的烃化合物制成的接头，用作直接键合到接头的一个特定官能团的分子识别物质的肽，以及载体直接键合到接头的另一个特定官能团。优选地，特定的官能团各自为环氧基和氨基的反应产物官能团。肽是天然免疫球蛋白的氨基酸序列中存在于对应于天然免疫球蛋白的高变区的部分中的三个或更多个连续氨基酸序列的人工合成的肽。

5. 发明申请

US20050093548A1 Underground exploration apparatus, system and method 失效
标题翻译：地下勘探设备，系统及方法
公开(公告)号：US20050093548A1
公开(公告)日：2005-05-05
申请号：US10991404
申请日：2004-11-19
申请人： Tomoaki Ueda , Kazuhito Nakamura , Yukio Kishimoto , Naoya Ichimura , Tokugen Yasuda
发明人： Tomoaki Ueda , Kazuhito Nakamura , Yukio Kishimoto , Naoya Ichimura , Tokugen Yasuda
IPC分类号： G01N27/04 , G01V3/06 , G01V3/00
CPC分类号： G01V3/06 , G01N27/043
摘要： The object of the present invention is to realize a low-invasive underground exploration apparatus, system, and method which are capable of specifying the kind, three-dimensional position, and amount of a substance present in the ground. The underground exploration apparatus, system, and method includes: measuring, at multiple points, a high frequency voltage that appears upon conduction of high frequency current through the ground to obtain measurement results at two or more frequency levels; employing an ground model using the finite element method, the boundary element method, an impedance network, or the like to estimate a substance in the ground by changing unknown quantities of the ground model such as local dielectric constant and electric conductivity so as to make an error between the actual measured value and the calculated value smaller; and displaying input information of the ground model and results of the estimation processing two-dimensionally or three-dimensionally.
摘要翻译：本发明的目的是实现能够指定存在于地面中的物质的种类，三维位置和量的低侵入式地下勘探装置，系统和方法。地下探测装置，系统和方法包括：在多个点测量在通过地面传导高频电流时出现的高频电压，以获得两个或多个频率水平的测量结果; 采用有限元法，边界元法，阻抗网络等的地面模型，通过改变诸如局部介电常数和电导率的地面模型的未知量来估计地面中的物质，从而使实际测量值与计算值之间的误差较小; 并且二维或三维地显示地面模型的输入信息和估计处理的结果。

6. 发明申请

US20060090539A1 Method of detecting high-concentration region direction of pollutant in soil 失效
公开(公告)号：US20060090539A1
公开(公告)日：2006-05-04
申请号：US11255938
申请日：2005-10-24
申请人： Yasuo Takahashi , Shigekazu Shimizu , Naoya Ichimura , Yasuhisa Fujii , Tokugen Yasuda
发明人： Yasuo Takahashi , Shigekazu Shimizu , Naoya Ichimura , Yasuhisa Fujii , Tokugen Yasuda
IPC分类号： G01N33/24
CPC分类号： G01N33/24
摘要： A recovery phenomenon in which the concentration of a compound to be measured in soil increases again after reducing the concentration is utilized for changing the distribution state of the compound to be measured in soil, whereby the direction of the high-concentration region of the compound to be measured in soil can be detected.

7. 发明授权

US09151969B2 Color tunable substrate 有权
标题翻译：颜色可调衬底
公开(公告)号：US09151969B2
公开(公告)日：2015-10-06
申请号：US13704329
申请日：2012-03-26
申请人： Naoya Ichimura
发明人： Naoya Ichimura
IPC分类号： G02F1/11 , G02F1/01 , G02F1/21 , G02B5/28 , G02B26/00
CPC分类号： G02F1/11 , G02B5/285 , G02B26/001 , G02F1/0131 , G02F1/21
摘要： A color tunable substrate is disclosed. The color tunable substrate includes multiple layers. A color of the color tunable substrate can be tuned by altering or adjusting characteristics of the layers included in the color tunable substrate.
摘要翻译：公开了一种颜色可调衬底。颜色可调衬底包括多层。可以通过改变或调整包括在颜色可调衬底中的层的特性来调整颜色可调衬底的颜色。

8. 发明授权

US08445633B2 Peptide having bindability with adiponectin, analysis method utilizing same peptide, and analysis device utilizing same peptide 失效
标题翻译：具有与脂连蛋白结合的肽，利用相同肽的分析方法，以及利用该肽的分析装置
公开(公告)号：US08445633B2
公开(公告)日：2013-05-21
申请号：US13094472
申请日：2011-04-26
申请人： Mao Yamada , Ai Tsutsui , Yoshiro Akagi , Naoya Ichimura , Atsushi Mizusawa , Takakiyo Tada
发明人： Mao Yamada , Ai Tsutsui , Yoshiro Akagi , Naoya Ichimura , Atsushi Mizusawa , Takakiyo Tada
IPC分类号： G01N33/531 , G01N33/543 , A61K38/04 , A61K38/08 , C07K2/00 , C12M1/40
CPC分类号： G01N33/74
摘要： Developed is an adiponectin-recognition material which is inexpensive and excellent in: productivity; stability of quality and a structure; and convenience. The present invention provides a peptide consisting of not more than 50 amino acids and having bindability with adiponectin.
摘要翻译：开发的是脂联素识别材料，其成本低廉且生产率优异：质量稳定，结构稳定; 方便。本发明提供由不超过50个氨基酸组成且与脂联素具有结合性的肽。

9. 发明申请

US20110269227A1 PEPTIDE HAVING BINDABILITY WITH ADIPONECTIN, ANALYSIS METHOD UTILIZING SAME PEPTIDE, AND ANALYSIS DEVICE UTILIZING SAME PEPTIDE 失效
标题翻译：与ADIPONECTIN具有可结合性的肽，利用相同肽的分析方法，以及利用相同肽的分析方法
公开(公告)号：US20110269227A1
公开(公告)日：2011-11-03
申请号：US13094472
申请日：2011-04-26
申请人： Mao Yamada , Ai Tsutsui , Yoshiro Akagi , Naoya Ichimura , Atsushi Mizusawa , Takakiyo Tada
发明人： Mao Yamada , Ai Tsutsui , Yoshiro Akagi , Naoya Ichimura , Atsushi Mizusawa , Takakiyo Tada
IPC分类号： C12N5/10 , A61K38/10 , G01N33/50 , C07H21/04 , C12N15/63 , A61K38/08 , B01J19/00
CPC分类号： G01N33/74
摘要： Developed is an adiponectin-recognition material which is inexpensive and excellent in: productivity; stability of quality and a structure; and convenience. The present invention provides a peptide consisting of not more than 50 amino acids and having bindability with adiponectin.
摘要翻译：开发的是脂联素识别材料，其成本低廉且生产率优异：质量稳定，结构稳定; 方便。本发明提供由不超过50个氨基酸组成且与脂联素具有结合性的肽。

10. 发明授权

US07034539B2 Underground exploration apparatus, system and method 失效
标题翻译：地下勘探设备，系统及方法
公开(公告)号：US07034539B2
公开(公告)日：2006-04-25
申请号：US10991404
申请日：2004-11-19
申请人： Tomoaki Ueda , Kazuhito Nakamura , Yukio Kishimoto , Naoya Ichimura , Tokugen Yasuda
发明人： Tomoaki Ueda , Kazuhito Nakamura , Yukio Kishimoto , Naoya Ichimura , Tokugen Yasuda
IPC分类号： G01V3/00
CPC分类号： G01V3/06 , G01N27/043
摘要： The object of the present invention is to realize a low-invasive underground exploration apparatus, system, and method which are capable of specifying the kind, three-dimensional position, and amount of a substance present in the ground. The underground exploration apparatus, system, and method includes: measuring, at multiple points, a high frequency voltage that appears upon conduction of high frequency current through the ground to obtain measurement results at two or more frequency levels; employing an ground model using the finite element method, the boundary element method, an impedance network, or the like to estimate a substance in the ground by changing unknown quantities of the ground model such as local dielectric constant and electric conductivity so as to make an error between the actual measured value and the calculated value smaller; and displaying input information of the ground model and results of the estimation processing two-dimensionally or three-dimensionally.
摘要翻译：本发明的目的是实现能够指定存在于地面中的物质的种类，三维位置和量的低侵入式地下勘探装置，系统和方法。地下探测装置，系统和方法包括：在多个点测量在通过地面传导高频电流时出现的高频电压，以获得两个或多个频率水平的测量结果; 采用有限元法，边界元法，阻抗网络等的地面模型，通过改变诸如局部介电常数和电导率的地面模型的未知量来估计地面中的物质，从而使实际测量值与计算值之间的误差较小; 并且二维或三维地显示地面模型的输入信息和估计处理的结果。

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