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1. 发明申请

US20060235325A1 Congestive heart failure monitor 审中-公开
标题翻译：充血性心力衰竭监测仪
公开(公告)号：US20060235325A1
公开(公告)日：2006-10-19
申请号：US10524196
申请日：2003-06-23
申请人： Nils Holmstrom , Martin Obel , Anna Norlin , Kenneth Dahlberg , Anders Bjorling , Sven Kalling , Karin Ljungstrom , Kjell Noren
发明人： Nils Holmstrom , Martin Obel , Anna Norlin , Kenneth Dahlberg , Anders Bjorling , Sven Kalling , Karin Ljungstrom , Kjell Noren
IPC分类号： A61B5/05 , A61B5/02
CPC分类号： A61B5/0538 , A61B5/053 , A61N1/3627
摘要： A congestive heart failure monitor has an impedance measuring unit that measures the impedance between at least two electrodes implanted in a patient, to use a detected change of the measured impedance as an indication of a change in the left atrium volume. Any analyzing unit analyzes the measured impedance and detects insipient congestive heart failure dependent on a quotient of a maximum value of the measured impedance and a minimum value of the measured impedance during a cardiac cycle.
摘要翻译：充血性心力衰竭监测器具有阻抗测量单元，其测量植入患者中的至少两个电极之间的阻抗，以使用检测到的测量阻抗的变化作为左心房体积变化的指示。任何分析单元分析所测量的阻抗，并根据所测量的阻抗的最大值和心动周期内所测量的阻抗的最小值来检测不利的充血性心力衰竭。

2. 发明授权

US07330758B2 Heart monitoring device, system and method 失效
标题翻译：心脏监护装置，系统及方法
公开(公告)号：US07330758B2
公开(公告)日：2008-02-12
申请号：US10396843
申请日：2003-03-25
申请人： Nils Holmström , Anna Norlin , Kenneth Dahlberg , Martin Obel
发明人： Nils Holmström , Anna Norlin , Kenneth Dahlberg , Martin Obel
IPC分类号： A61N1/365
CPC分类号： A61N1/36521 , A61B5/0535 , A61B5/7239 , A61N1/3627 , A61N1/3682 , A61N1/3684
摘要： A heart monitoring device has a control circuit that derives an impedance value indicative of the impedance between different electrode surfaces. The control circuit determines and monitors a negative rate of change of the impedance value and determines whether the negative rate of change, or its absolute value, increases or decreases over a number of heart cycles. Alternatively or additionally, the control circuit may determine and monitor a relationship between a positive rate of change and a negative rate of change of the impedance value. The device can, in particular, be used to detect and treat a diastolic dysfunction of a heart.
摘要翻译：心脏监测装置具有控制电路，其导出指示不同电极表面之间的阻抗的阻抗值。控制电路确定并监测阻抗值的负变化率，并确定负数变化率或其绝对值是否在多个心脏周期内增加或减少。或者或另外，控制电路可以确定和监测正的变化率与阻抗值的负的变化率之间的关系。该装置特别可用于检测和治疗心脏的舒张功能障碍。

3. 发明授权

US07146208B2 Systolic function monitoring utilizing slope of measured impedance 有权
标题翻译：使用测量阻抗斜率的收缩功能监测
公开(公告)号：US07146208B2
公开(公告)日：2006-12-05
申请号：US10396958
申请日：2003-03-25
申请人： Nils Holmström , Anna Norlin , Kenneth Dahlberg , Martin Obel
发明人： Nils Holmström , Anna Norlin , Kenneth Dahlberg , Martin Obel
IPC分类号： A61B5/053 , A61N1/365
CPC分类号： A61B5/0535 , A61N1/3627 , A61N1/36521 , A61N1/3684
摘要： A heart monitoring device has a control circuit, the control circuit being adapted to be electrically connected to electrode surfaces arranged at two different positions of the heart. The control circuit derives an impedance value indicative of the impedance between the electrode surfaces. Furthermore, the control circuit is arranged to determine and monitor a relationship between a positive rate of change and a negative rate of change of the impedance value. The device can, in particular, be used to detect and treat a systolic dysfunction of a heart.
摘要翻译：心脏监测装置具有控制电路，所述控制电路适于电连接到布置在心脏两个不同位置处的电极表面。控制电路导出指示电极表面之间的阻抗的阻抗值。此外，控制电路被布置成确定和监测正的变化率和阻抗值的负的变化率之间的关系。该装置特别可用于检测和治疗心脏的收缩功能障碍。

4. 发明授权

US07241531B2 Battery and a battery encapsulation 有权
标题翻译：电池和电池封装
公开(公告)号：US07241531B2
公开(公告)日：2007-07-10
申请号：US10488291
申请日：2002-06-17
申请人： Kenneth Dahlberg
发明人： Kenneth Dahlberg
IPC分类号： H01M2/00
CPC分类号： A61N1/375 , H01M2/1055
摘要： A battery unit has a battery encapsulation formed by first and second encapsulation parts joined by a weld along a weld zone, with a battery contained in the battery encapsulation between the first and second encapsulation parts. Either the battery has a recess exstending along the weld zone, or overlaping edges of the first and second encapsulation parts are bent away from the battery to form a recess. The recess provides a heating insulating space that protects the battery from damage during welding along the weld zone.
摘要翻译：电池单元具有由沿焊接区焊接的第一和第二封装部分形成的电池封装，电池包含在第一和第二封装部分之间的电池封装中。电池具有沿着焊接区域排出的凹部，或者第一和第二封装部分的重叠边缘从电池弯曲形成凹部。凹槽提供加热绝缘空间，可保护电池在焊接过程中不受损伤。

5. 发明授权

US5814091A Active medical implant having a hermetically sealed capsule and method for making same 失效
标题翻译：具有密封胶囊的主动医疗植入物及其制造方法
公开(公告)号：US5814091A
公开(公告)日：1998-09-29
申请号：US822729
申请日：1997-03-24
申请人： Kenneth Dahlberg , Ulf Lindegren
发明人： Kenneth Dahlberg , Ulf Lindegren
IPC分类号： A61N1/375 , A61N1/39 , H01M2/10 , H01M6/16
CPC分类号： H01M2/1094 , A61N1/375 , A61N1/3956 , H01M2/1022 , H01M2/1066 , H01M6/16
摘要： An active medical implant has a hermetically sealable capsule formed by a first part and a second closing part, the capsule being devised to hold a battery unit, an electronics unit, conductors for electrically connecting the battery to the electronics unit, and contacts arranged on the exterior of the capsule for connection to electrodes. The first part is made, at least in part, of a rolled, multi-layer composite sheet or plate, one layer of which is made of a biocompatible material and a second layer of which is made of a diffusion-proof material which is essentially resistant to corrosive chemicals. The two layers are joined by rolling, with the layer made of biocompatible material constituting the outer wall of the capsule. The closing part contains a layer of the biocompatible material serving as the capsule's outer wall and a partition wall made of diffusion-proof material which is essentially resistant to corrosive chemicals, is arranged to form a first essentially closed space for the power source in the first part. A second space for the electronics unit is formed between the wall closing the capsule and the partition wall.
摘要翻译：主动医疗植入物具有由第一部分和第二闭合部分形成的气密密封胶囊，所述胶囊被设计成保持电池单元，电子单元，用于将电池电连接到电子单元的导体和布置在电池单元上的触点用于连接到电极的胶囊的外部。第一部分至少部分地由轧制的多层复合板或板制成，其一层由生物相容性材料制成，第二层由防扩散材料制成，其基本上是耐腐蚀性化学品。两层通过轧制连接，由生物相容性材料制成的层构成胶囊的外壁。闭合部分包含用作胶囊的外壁的生物相容性材料层和由基本上抵抗腐蚀性化学物质的耐扩散材料制成的分隔壁，以形成第一基本封闭的空间，用于在第一部分。用于电子单元的第二空间形成在封闭胶囊的壁与分隔壁之间。

6. 发明授权

US08437863B2 Electrode lead 有权
标题翻译：电极铅
公开(公告)号：US08437863B2
公开(公告)日：2013-05-07
申请号：US13140729
申请日：2008-12-19
申请人： Åke Sivard , Gustav Pellijeff , Hans Strandberg , Leda Henriquez , Åsa Broomé , Kenneth Dahlberg
发明人： Åke Sivard , Gustav Pellijeff , Hans Strandberg , Leda Henriquez , Åsa Broomé , Kenneth Dahlberg
IPC分类号： A61N1/05
CPC分类号： A61N1/05 , A61N1/086 , A61N1/3688 , A61N1/3718
摘要： An implantable electrode lead for tissue stimulation adapted to be attached to an implantable tissue stimulator provided with a pulse generator, has at least two stimulation electrodes to apply stimulation pulses to said tissue and arranged close to the distal end of the electrode lead, and at least two electrical conductors to connect said electrodes to said pulse generator. The electrode lead further has a switching unit arranged close to the distal end of the electrode lead and adapted to switch the electrode lead between a local pacing mode and a normal pacing mode, the switching unit being controlled by a mode control signal. Further, a pacing module is arranged close to the distal end of the electrode lead and in relation to the switching unit and being connectable to said at least two stimulation electrodes, the pacing module includes a pulse generating unit to generate stimulating pulses to be applied to the tissue by the stimulation electrodes. When the electrode lead is in the local pacing mode the electrical conductors are disconnected from said stimulation electrodes which instead are connected to the pacing module, and when the electrode lead is in the normal pacing mode the electrical conductors are connected to the stimulation electrodes.
摘要翻译：一种用于组织刺激的可植入电极引线，其适用于连接到具有脉冲发生器的可植入组织刺激器，具有至少两个刺激电极，以将刺激脉冲施加到所述组织并且靠近电极引线的远端布置，并且至少两个电导体将所述电极连接到所述脉冲发生器。电极引线还具有靠近电极引线的远端布置的开关单元，并且适于在局部起搏模式和正常起搏模式之间切换电极引线，开关单元由模式控制信号控制。此外，起搏模块靠近电极引线的远端设置，并且相对于开关单元设置并且可连接到所述至少两个刺激电极，所述起搏模块包括脉冲产生单元，用于产生刺激脉冲以施加到由刺激电极组织。当电极引线处于局部起搏模式时，电导体与所述刺激电极断开，代替地连接到起搏模块，并且当电极引线处于正常起搏模式时，电导体连接到刺激电极。

7. 发明申请

US20110251654A1 ELECTRODE LEAD 有权
标题翻译：电极引线
公开(公告)号：US20110251654A1
公开(公告)日：2011-10-13
申请号：US13140729
申请日：2008-12-19
申请人： Åke Sivard , Gustav Pellijeff , Hans Strandberg , Leda Henriquez , Åsa Broomé , Kenneth Dahlberg
发明人： Åke Sivard , Gustav Pellijeff , Hans Strandberg , Leda Henriquez , Åsa Broomé , Kenneth Dahlberg
IPC分类号： A61N1/365 , A61N1/362
CPC分类号： A61N1/05 , A61N1/086 , A61N1/3688 , A61N1/3718
摘要： An implantable electrode lead for tissue stimulation adapted to be attached to an implantable tissue stimulator provided with a pulse generator, has at least two stimulation electrodes to apply stimulation pulses to said tissue and arranged close to the distal end of the electrode lead, and at least two electrical conductors to connect said electrodes to said pulse generator. The electrode lead further has a switching unit arranged close to the distal end of the electrode lead and adapted to switch the electrode lead between a local pacing mode and a normal pacing mode, the switching unit being controlled by a mode control signal. Further, a pacing module is arranged close to the distal end of the electrode lead and in relation to the switching unit and being connectable to said at least two stimulation electrodes, the pacing module includes a pulse generating unit to generate stimulating pulses to be applied to the tissue by the stimulation electrodes. When the electrode lead is in the local pacing mode the electrical conductors are disconnected from said stimulation electrodes which instead are connected to the pacing module, and when the electrode lead is in the normal pacing mode the electrical conductors are connected to the stimulation electrodes.
摘要翻译：一种用于组织刺激的可植入电极引线，其适用于连接到具有脉冲发生器的可植入组织刺激器，具有至少两个刺激电极，以将刺激脉冲施加到所述组织并且靠近电极引线的远端布置，并且至少两个电导体将所述电极连接到所述脉冲发生器。电极引线还具有靠近电极引线的远端布置的开关单元，并且适于在局部起搏模式和正常起搏模式之间切换电极引线，开关单元由模式控制信号控制。此外，起搏模块靠近电极引线的远端设置，并且相对于开关单元设置并且可连接到所述至少两个刺激电极，所述起搏模块包括脉冲产生单元，用于产生刺激脉冲以施加到由刺激电极组织。当电极引线处于局部起搏模式时，电导体与所述刺激电极断开，代替地连接到起搏模块，并且当电极引线处于正常起搏模式时，电导体连接到刺激电极。

8. 发明申请

US20090171425A1 IMPLANTABLE MEDICAL LEAD AND METHOD FOR THE MANUFACTURE THEREOF 有权
标题翻译：可植入医疗用铅及其制造方法
公开(公告)号：US20090171425A1
公开(公告)日：2009-07-02
申请号：US12280500
申请日：2006-03-02
申请人： Kenneth Dahlberg
发明人： Kenneth Dahlberg
IPC分类号： A61N1/05
CPC分类号： A61N1/05 , A61N1/056 , Y10T29/49117
摘要： A medically implantable lead configured for insertion into a human or animal body to be attached in the body with its distal end to tissue inside the body, as a rotatable helix at a distal end thereof that can be screwed into the tissue. The helix serves as an attachment of the lead to the tissue as well as a conductor for conducting electrical signals to the tissue through electrically conducting surfaces on the helix. The surfaces of the helix are partly insulated so as to restrict the conducting of signals between the helix and the tissue to desirable regions. The surfaces of the helix facing inwardly, toward an inner bore of the helix, are electrically insulated. In a method for manufacturing such a lead, the wire forming the helix has protrusions in desired areas and the wire including the protrusions is coated with an electrically insulating layer. The protrusions are uncovered from the insulating layer in desired regions.
摘要翻译：一种医学上可植入的引线，其构造成用于插入人体或动物体中，其主体的远端位于身体内部，作为其远端处的可旋转螺旋，其可被螺纹连接到组织中。螺旋作为引线附着到组织以及用于通过螺旋上的导电表面向组织传导电信号的导体。螺旋的表面被部分地绝缘，以便将螺旋和组织之间的信号传导限制到所需区域。螺旋面向内，朝向螺旋的内孔的表面是电绝缘的。在制造这种引线的方法中，形成螺旋线的线具有所需区域中的突起，并且包括突起的线被涂覆有电绝缘层。突出物在期望的区域中从绝缘层未被覆盖。

9. 发明申请

US20080228270A1 Implantable Medical Device with a Voltage Protection Circuit 有权
标题翻译：具有电压保护电路的可植入医疗器械
公开(公告)号：US20080228270A1
公开(公告)日：2008-09-18
申请号：US12065106
申请日：2005-09-28
申请人： Kenneth Dahlberg
发明人： Kenneth Dahlberg
IPC分类号： A61F2/02 , A61N1/00
CPC分类号： A61N1/3718 , A61N1/3754
摘要： An implantable medical device has a hermetically sealed housing with at least one feedthrough therein for a conductive path between an RF antenna carried by the housing, and an RF telemetry circuit contained in the housing. The feedthrough has a feedthrough housing with a capacitor element therein having first and second capacitor plate configurations, with a first of the capacitor plate configurations being connected to the RF antenna and a second of the capacitor plate configurations being connected to the RF telemetry circuit. The feedthrough functions both as a hermetic seal and as a galvanic isolation for voltage protection of the components of the RF telemetry circuit, and other circuitry in the sealed housing connected thereto.
摘要翻译：可植入医疗装置具有气密密封的壳体，其中至少有一个馈通用于由壳体承载的RF天线与容纳在壳体中的RF遥测电路之间的导电路径。馈通具有其中具有第一和第二电容器板配置的电容器元件的馈通外壳，电容器板配置中的第一个连接到RF天线，并且电容器板配置中的第二个连接到RF遥测电路。馈通功能既作为气密密封又用作电流隔离，用于RF遥测电路的部件的电压保护以及与其连接的密封壳体中的其它电路。

10. 发明授权

US08442647B2 Medical implantable lead and method for the manufacture thereof 有权
标题翻译：医用植入式铅及其制造方法
公开(公告)号：US08442647B2
公开(公告)日：2013-05-14
申请号：US13132125
申请日：2008-12-02
申请人： Hans Strandberg , Åke Sivard , Åsa Broomé , Kenneth Dahlberg , Gustav Pellijeff , Leda Henriquez
发明人： Hans Strandberg , Åke Sivard , Åsa Broomé , Kenneth Dahlberg , Gustav Pellijeff , Leda Henriquez
IPC分类号： A61N1/05
CPC分类号： A61N1/05 , A61N1/056 , A61N1/086 , A61N1/3718 , Y10T29/49002
摘要： A medical implantable lead adapted to be implanted into a human or animal body for monitoring and/or controlling of an organ inside the body has a fixation in a distal end, which is adapted to fix a distal end of the lead to the organ, an electrode member in the distal end adapted to be in contact with tissue of the organ and receive and/or transmit electrical signals from and/or to the organ, and at least one electrically conducting coil, which includes one or more electrically conducting helical wires and that is adapted to connect the electrode member in the distal end with a monitoring and/or controlling device in a proximal end of the lead. One or more of the individual wires of the coil has a wire core that is provided with a surrounding electrically insulating layer, which in turn is provided with a surrounding electrically conducting shield layer, and the coil is close lapped such that electrically conducting shield layers of adjacent loops of the coil are in electrical contact with each other.
摘要翻译：适于植入人体或动物体内的用于监测和/或控制体内器官的医用可植入引线具有在远端固定，其适于将引线的远端固定到器官，远端中的电极构件适于与器官的组织接触并且接收和/或传送来自器官和/或器官的电信号，以及至少一个导电线圈，其包括一个或多个导电螺旋线和其适于将远端中的电极构件与引线的近端中的监视和/或控制装置连接。线圈的一条或多条单独的线具有线芯，该芯线设置有环绕的电绝缘层，该电绝缘层又设置有环绕的导电屏蔽层，并且线圈被紧密地重叠，使得导电屏蔽层线圈的相邻环彼此电接触。

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