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1. 发明申请

US20100120789A1 Compound 审中-公开
标题翻译：复合
公开(公告)号：US20100120789A1
公开(公告)日：2010-05-13
申请号：US12554943
申请日：2009-09-07
申请人： Nigel Vicker , Xiangdong Su , Fabienne Praduax , Michael John Reed , Barry Victor Lloyd Potter
发明人： Nigel Vicker , Xiangdong Su , Fabienne Praduax , Michael John Reed , Barry Victor Lloyd Potter
IPC分类号： A61K31/497 , C07C233/00 , A61K31/165 , A61K31/4365 , C07D495/04 , C07D405/02 , C12Q1/32
CPC分类号： C11D3/0073 , C11D3/2086 , C11D3/33 , C11D7/265 , C11D7/3245 , C11D11/0041
摘要： There is provided a compound having Formula I R1—Z—R2 Formula I wherein R1 is a group selected from optionally substituted fused polycyclic groups, substituted alkyl groups, branched alkyl groups, and optionally substituted cycloalkyl groups Z is a linker which is or comprises a carbonyl group or a isostere of a carbonyl group R2 is selected from optionally substituted aromatic rings and optionally substituted heterocyclic rings wherein (a) R2 is a 2-substituted thiophene group, and/or (b) Z is a group of the formula —C(═O)—CR3R4—X—(CR5R6)n-, wherein X is selected from NR7, S, O, S═O, and S(═O)2, wherein n is 0 or 1 and/or (c) R1 is an adamantyl group and Z is or comprises an amide group, and/or (d) R1 is an adamantyl group and Z is or comprises a group of the formula —(CR8R9)p- NR10—S(═O)2—(CR11R12)q-, wherein p is 0 or 1 and q is 0 or 1 and/or (e) R1 is an adamantyl group and Z is or comprises a group of the formula —(CR13R14)v-Y—(CR15R16)w- where Y is a heteroaryl group in which a bond in the heteroaryl ring is a isostere of a carbonyl group, wherein v is o or 1 and w is 0 or 1; wherein each of R3, R4, R5, R6, R8, R9, R11, R12, R13, R14, R15 and R16, are independently selected from H, hydrocarbyl and halogen, wherein each of R7 and R10 are independently selected from H and hydrocarbyl.
摘要翻译：提供了具有式I的化合物R1-Z-R2式Ⅰ其中R1是选自任选取代的稠合多环基团，取代的烷基，支链烷基和任选取代的环烷基的基团Z是一种或多种羰基或羰基的等排基团选自任选取代的芳环和任选取代的杂环，其中（a）R 2是2-取代的噻吩基团，和/或（b）Z是式-C （= O）-CR 3 R 4 -X-（CR 5 R 6）n - ，其中X选自NR 7，S，O，S = O和S（= O）2，其中n为0或1和/或（c） R1是金刚烷基，Z是或包含酰胺基，和/或（d）R1是金刚烷基，Z是或包含式 - （CR8R9）对NR10-S（= O）2- （CR11R12）q-，其中p为0或1，q为0或1，和/或（e）R1为金刚烷基，Z为或包含式 - （CR13R14）vY-（CR15R16）w- 在哪里 Y是杂芳基环中的键是羰基的等离子体的杂芳基，其中v是0或1，w是0或1; 其中R 3，R 4，R 5，R 6，R 8，R 9，R 11，R 12，R 13，R 14，R 15和R 16各自独立地选自H，烃基和卤素，其中R 7和R 10各自独立地选自H和烃基。

2. 发明申请

US20090042929A1 11-Beta-Hydroxysteroid Dehydrogenase Inhibitors 审中-公开
标题翻译： 11-β-羟基类固醇脱氢酶抑制剂
公开(公告)号：US20090042929A1
公开(公告)日：2009-02-12
申请号：US11886884
申请日：2006-03-23
申请人： Nigel Vicker , Xiangdong Su , Fabienne Pradaux , Michael John Reed , Barry Victor Lloyd Potter
发明人： Nigel Vicker , Xiangdong Su , Fabienne Pradaux , Michael John Reed , Barry Victor Lloyd Potter
IPC分类号： A61K31/437 , A61P3/00 , A61P29/00 , A61P37/00 , A61P19/00 , A61P35/00 , C07C311/20 , A61K31/428 , A61K31/18 , C12Q1/32 , A61K31/381 , A61K31/4439 , C07C311/16 , C07D277/64 , C07D333/24 , C07D213/56 , C07D495/04
CPC分类号： C07C233/25 , C07C233/58 , C07C233/59 , C07C311/13 , C07C311/16 , C07C311/20 , C07C317/24 , C07C323/22 , C07C2603/74 , C07D207/09 , C07D207/335 , C07D209/14 , C07D213/40 , C07D213/75 , C07D213/82 , C07D233/24 , C07D233/54 , C07D233/64 , C07D239/26 , C07D271/06 , C07D277/20 , C07D277/64 , C07D295/13 , C07D307/52 , C07D333/20 , C07D333/34 , C07D333/58
摘要： There is provided a compound having Formula (I) R1-Z-R2 wherein R1 is a group selected from optionally substituted fused polycyclic groups, substituted alkyl groups, branched alkyl groups, and optionally substituted cycloalkyl groups Z is a linker which is or comprises a carbonyl group or a isostere of a carbonyl group R2 is selected from optionally substituted aromatic rings and optionally substituted heterocyclic rings wherein (a) R2 is a 2-substituted thiophene group, and/or (b) Z is a group of the formula —C(═O)—CR3R4—X—(CR5R6)n-, wherein X is selected from NR7, S, O, S═O, and S(═O)2, wherein n is 0 or 1 and/or (c) R1 is an adamantyl group and Z is or comprises an amide group, and/or (d) R1 is an adamantyl group and Z is or comprises a group of the formula —(CR8R9)p-NR10—S(═O)2—(CR11R12)q-, wherein p is 0 or 1 and q is 0 or 1 and/or (e) R1 is an adamantyl group and Z is or comprises a group of the formula —(CR13R14)V—Y—(CR15R16)W— where Y is a heteroaryl group in which a bond in the heteroaryl ring is a isostere of a carbonyl group, wherein v is o or 1 and w is 0 or 1; wherein each of R3, R4, R5, R6, R8, R9, R11, R12, R13, R14, R15 and R16, are independently selected from H, hydrocarbyl and halogen, wherein each of R7 and R10 are independently selected from H and hydrocarbyl.
摘要翻译：提供了具有式（I）的化合物，其中R 1是选自任选取代的稠合多环基团，取代的烷基基团，支链烷基基团和任选取代的环烷基基团。Z是一个或多个羰基或羰基的等排基团选自任选取代的芳环和任选取代的杂环，其中（a）R 2是2-取代的噻吩基团，和/或（b）Z是式-C （-O）-CR 3 R 4 -X-（CR 5 R 6）n - ，其中X选自NR 7，S，O，SO和S（-O）2，其中n为0或1和/或（c）金刚烷基，Z是或包含酰胺基，和/或（d）R 1是金刚烷基，Z是或包含式 - （CR 8 R 9）p -NR 10 -S（-O）2 - （CR 11 R 12））q-，其中p为0或1，q为0或1，和/或（e）R1为金刚烷基，Z为或包含式 - （CR13R14）VY-（CR15R16）W-的基团，其中Y 是其中的键 e杂芳基环是羰基的等排物，其中v是o或1，w是0或1; 其中R 3，R 4，R 5，R 6，R 8，R 9，R 11，R 12，R 13，R 14，R 15和R 16各自独立地选自H，烃基和卤素，其中R 7和R 10各自独立地选自H和烃基。

3. 发明申请

US20120041207A1 Compound 审中-公开
标题翻译：复合
公开(公告)号：US20120041207A1
公开(公告)日：2012-02-16
申请号：US13137395
申请日：2011-08-10
申请人： Nigel Vicker , Su Xiangdong , Dharshini Ganeshapillai , Atul Purohit , Michael John Reed , Barry Victor Lloyd Potter
发明人： Nigel Vicker , Su Xiangdong , Dharshini Ganeshapillai , Atul Purohit , Michael John Reed , Barry Victor Lloyd Potter
IPC分类号： C07D277/64 , C07D235/08 , C07D209/12 , C07D417/12
CPC分类号： C07D277/64 , C07D209/08 , C07D235/08 , C07D263/56 , C07D277/14 , C07D417/12
摘要： A compound having Formula I wherein one of R1 and R2 is a group of the formula wherein R4 is selected from H and hydrocarbyl, R5 is a hydrocarbyl group and L is an optional linker group, or R1 and R2 together form a ring substituted with the group wherein R3 is H or a substituent, and wherein X is selected from S, O, NR6 and C(R7)(R8), wherein R6 is selected from H and hydrocarbyl groups, wherein each of R7 and R8 are independently selected from H and hydrocarbyl groups.
摘要翻译：具有式I的化合物，其中R 1和R 2中的一个是下式的基团其中R 4选自H和烃基，R 5是烃基，L是任选的连接基团，或者R 1和R 2一起形成被其中R 3是H或取代基，其中X选自S，O，NR 6和C（R 7）（R 8），其中R 6选自H和烃基，其中R 7和R 8各自独立地选自H 和烃基。

4. 发明授权

US08003783B2 17B-hydroxysteroid dehydrogenase inhibitors 失效
标题翻译： 17B-羟类固醇脱氢酶抑制剂
公开(公告)号：US08003783B2
公开(公告)日：2011-08-23
申请号：US11234868
申请日：2005-09-23
申请人： Nigel Vicker , Harshani Rithma Ruchiranani Lawrence , Gillian Margaret Allan , Christian Bubert , Delphine Sophie Marion Fischer , Atul Purohit , Michael John Reed , Barry Victor Lloyd Potter
发明人： Nigel Vicker , Harshani Rithma Ruchiranani Lawrence , Gillian Margaret Allan , Christian Bubert , Delphine Sophie Marion Fischer , Atul Purohit , Michael John Reed , Barry Victor Lloyd Potter
IPC分类号： A61K31/58 , C07J71/00
CPC分类号： C07J71/00 , C07J41/00
摘要： There is provided a compound of Formula (III) wherein R1 is a selected from an alkyloxyalkyl group, a nitrile group, alkylaryl group, alkenylaryl group, alkylheteroaryl group, alkenylheteroaryl group, ═N—O—alkyl or ═N—O—H group, branched alkenyl, alkyl-alcohol group, amide or alkylamide or —CHO so that R1 together with R3 provide the enol tautomer or R1 together with R3 form a pyrazole, wherein (a) R4 is ═N—O-alkyl or ═N—O—H group, (b) the pyrazole is substituted with one of alkyl-OH group, alkyl ester group, alkyloxyalkyl group, branched alkyl group, and an amide and/or (c) the 2-position is substituted with a group selected from —OH and —O-hydrocarbyl or a heteroaryl ring; R2 is selected from —OH and a sulphamate group; and R3 is selected from —OH or ═O; wherein the ring system may be further substituted with one or more hydroxyl, alkyl, alkoxy, alkinyl or halo substituents.
摘要翻译：提供式（III）的化合物，其中R 1选自烷氧基烷基，腈基，烷基芳基，链烯基芳基，烷基杂芳基，烯基杂芳基，N-O-烷基或= N-O-H基，支链烯基，烷基醇基，酰胺或烷基酰胺或-CHO，使得R 1与R 3一起提供烯醇互变异构体或R 1与R 3一起形成吡唑，其中（a）R 4是= N-O-烷基或= O-H基，（b）吡唑被烷基-OH基，烷基酯基，烷氧基烷基，支链烷基和酰胺中的一个取代，和/或（c）2-位被选定的基团取代从-OH和-O-烃基或杂芳基环; R2选自-OH和氨基磺酸酯基; 并且R 3选自-OH或= O; 其中所述环系可以进一步被一个或多个羟基，烷基，烷氧基，炔基或卤素取代基取代。

5. 发明申请

US20110009448A1 Compound 审中-公开
标题翻译：复合
公开(公告)号：US20110009448A1
公开(公告)日：2011-01-13
申请号：US12842815
申请日：2010-07-23
申请人： Nigel Vicker , Su Xiangdong , Dharshini Ganeshapillai , Atul Purohit , Michael John Reed , Barry Victor Lloyd Potter
发明人： Nigel Vicker , Su Xiangdong , Dharshini Ganeshapillai , Atul Purohit , Michael John Reed , Barry Victor Lloyd Potter
IPC分类号： A61K31/4709 , C07D277/64 , A61K31/428 , C07D417/12 , C07D277/74 , C07D235/08 , A61K31/4184 , C07D209/14 , A61K31/404 , C07D209/42 , C07D401/12 , C07D263/56 , A61K31/423 , A61P3/04 , A61P3/10 , A61P9/00 , A61P11/06 , A61P19/02 , A61P29/00 , A61P35/00 , C12Q1/32
CPC分类号： C07D277/64 , C07D209/08 , C07D235/08 , C07D263/56 , C07D277/14 , C07D417/12
摘要： A compound having Formula I wherein one of R1 and R2 is a group of the formula wherein R4 is selected from H and hydrocarbyl, R5 is a hydrocarbyl group and L is an optional linker group, or R1 and R2 together form a ring substituted with the group wherein R3 is H or a substituent, and wherein X is selected from S, O, NR6 and C(R7)(R8), wherein R6 is selected from H and hydrocarbyl groups, wherein each of R7 and R8 are independently selected from H and hydrocarbyl groups.
摘要翻译：具有式I的化合物，其中R 1和R 2中的一个是下式的基团其中R 4选自H和烃基，R 5是烃基，L是任选的连接基团，或者R 1和R 2一起形成被其中R 3是H或取代基，其中X选自S，O，NR 6和C（R 7）（R 8），其中R 6选自H和烃基，其中R 7和R 8各自独立地选自H 和烃基。

6. 发明申请

US20090023710A1 Compound 有权
公开(公告)号：US20090023710A1
公开(公告)日：2009-01-22
申请号：US11968436
申请日：2008-01-02
申请人： Nigel Vicker , Joanna Mary Day , Helen Victoria Bailey , Wesley Heaton , Ana Maria Ramos Gonzalez , Christopher Mark Sharland , Michael John Reed , Atul Purohit , Barry Victor Lloyd Potter
发明人： Nigel Vicker , Joanna Mary Day , Helen Victoria Bailey , Wesley Heaton , Ana Maria Ramos Gonzalez , Christopher Mark Sharland , Michael John Reed , Atul Purohit , Barry Victor Lloyd Potter
IPC分类号： A61K31/55 , C07D211/58 , C07C233/22 , A61P35/00 , C07D223/12 , A61K31/167
CPC分类号： C07C237/22 , C07C233/36 , C07D209/20 , C07D211/56 , C07D211/58 , C07D211/62 , C07D211/96 , C07D215/38 , C07D215/44 , C07D223/12 , C07D223/16 , C07D239/42 , C07D401/12 , C07D401/14 , C07D405/06 , C07D409/06 , C07D409/12 , C07D451/04
摘要： There is provided a compound having Formula (I) wherein each of R1, R2, R3, R4, R5, R6 and R7 are independently selected from (a) H, (b) R17, —OC(R17)3, —OCH(R17)2, —OCH2R17, —C(R17)3, —CH(R17)2, or —CH2R17 wherein R17 is a halogen; (c) —CN; (d) optionally substituted alkyl, (e) optionally substituted heteroalkyl; (f) optionally substituted aryl; (g) optionally substituted heteroaryl; (h) optionally substituted arylalkyl; (i) optionally substituted heteroarylalkyl; (j) hydroxy; (k) alkoxy; (l) aryloxy; (m) —SO2-alkyl; and (n) —N(R11)C(O)R13; wherein the optional substituents of (d) (e) (f) (h) and (i) are selected from the group consisting of: C1-6 alkyl, halo, cyano, nitro, haloalkyl, hydroxy, alkoxy, carboxy, carboxyalkyl, carboxamide, mercapto, amino, alkylamino, dialkylamino, sulfonyl, sulfonamido, aryl and heteroaryl; each of rings A and B are selected from five or six membered carbon rings optionally containing one or more hetero atoms selected from N, S, and O and optionally having fused thereto a further ring; X is an optional group selected from O, S, S═O, S(═O)2, C═O, S(═O)2NR8, C═ONR9, NR10, wherein R8, R9 and R10 are independently selected from H and hydrocarbyl, wherein n and p are independently selected from 0 and 1; Y is (R11)1-3 wherein each R11 is independently selected from NR12, CR13R14, S(═O)2 and C═O, wherein R12, R13 and R14 are independently selected from Hand hydrocarbyl; Z is selected from (i) six or seven membered ring containing carbon and at least one nitrogen, which may be optionally substituted wherein the substituents may together form further ring fused thereto; and (ii) a —R15—NR16— group wherein R15 is an optionally substituted C1-6 alkyl chain and R16 is selected from H and hydrocarbyl; and R3 is selected from Formula (A).

7. 发明授权

US07309715B2 Compound 失效
标题翻译：复合
公开(公告)号：US07309715B2
公开(公告)日：2007-12-18
申请号：US10690708
申请日：2003-10-23
申请人： Nigel Vicker , Su Xiangdong , Dharshini Ganeshapillai , Atul Purohit , Michael John Reed , Barry Victor Lloyd Potter
发明人： Nigel Vicker , Su Xiangdong , Dharshini Ganeshapillai , Atul Purohit , Michael John Reed , Barry Victor Lloyd Potter
IPC分类号： A61K31/428 , C07D277/62
CPC分类号： C07D277/64 , C07D209/08 , C07D235/08 , C07D263/56 , C07D277/14 , C07D417/12
摘要： A compound having Formula I wherein one of R1 and R2 is a group of the formula wherein R4 is selected from H and hydrocarbyl, R5 is a hydrocarbyl group and L is an optional linker group, or R1 and R2 together form a ring substituted with the group wherein R3 is H or a substituent, and wherein X is selected from S, O, NR6 and C(R7)(R8), wherein R6 is selected from H and hydrocarbyl groups, wherein each of R7 and R8 are independently selected from H and hydrocarbyl groups.
摘要翻译：具有式I的化合物，其中R 1和R 2中的一个是下式的基团其中R 4选自H和烃基， R 5是烃基，L是任选的连接基团，或者R 1和R 2一起形成被下列基团取代的环，其中， R 3是H或取代基，其中X选自S，O，NR 6和C（R 7）（R 7）其中R 6选自H和烃基，其中R 7和R 8中的每一个是独立地选自H和烃基。

8. 发明授权

US08119627B2 Heterocyclic compounds as inhibitors of 17beta-HSD3 有权
标题翻译：杂环化合物作为17β-HSD3的抑制剂
公开(公告)号：US08119627B2
公开(公告)日：2012-02-21
申请号：US11968436
申请日：2008-01-02
申请人： Nigel Vicker , Joanna Mary Day , Helen Victoria Bailey , Wesley Heaton , Ana Maria Ramos Gonzalez , Christopher Mark Sharland , Michael John Reed , Atul Purohit , Barry Victor Lloyd Potter
发明人： Nigel Vicker , Joanna Mary Day , Helen Victoria Bailey , Wesley Heaton , Ana Maria Ramos Gonzalez , Christopher Mark Sharland , Michael John Reed , Atul Purohit , Barry Victor Lloyd Potter
IPC分类号： A61K31/55
CPC分类号： C07C237/22 , C07C233/36 , C07D209/20 , C07D211/56 , C07D211/58 , C07D211/62 , C07D211/96 , C07D215/38 , C07D215/44 , C07D223/12 , C07D223/16 , C07D239/42 , C07D401/12 , C07D401/14 , C07D405/06 , C07D409/06 , C07D409/12 , C07D451/04
摘要： There is provided a compound having Formula (I) wherein each of rings A and B is selected from five or six membered carbon rings optionally containing one or more hetero atoms selected from N, S, and O and optionally having fused thereto a further ring; X is an optional group selected from O, S, —S═O, —S(═O)2, —C═O, —S(═O)2NR8, —C═ONR9, and —NR10, wherein n and p are independently selected from 0 and 1; Y is (R11)1-3 wherein each R11 is independently selected from —NR12, —CR13R14, —S(═O)2 and —C═O; Z is selected from (i) six or seven membered ring containing carbon and at least one nitrogen, which may be optionally substituted wherein the substituents may together form further ring fused thereto; and (ii) a —R15—NR16— group.
摘要翻译：提供了具有式（I）的化合物，其中环A和B各自选自5或6元碳环，任选地含有一个或多个选自N，S和O的杂原子，并且任选地与另一个环稠合; X是选自O，S，-S = O，-S（= O）2，-C = O，-S（= O）2 NR 8，-CONONR 9和-NR 10的任选基团，其中n和p 独立地选自0和1; Y是（R 11）1-3，其中每个R 11独立地选自-NR 12，-CR 13 R 14，-S（= O）2和-C≡O; Z选自（i）含有六元或七元环的碳和至少一个氮，其可以是任选取代的，其中取代基可以一起形成稠合的另外的环; 和（ii）-R 15 -NR 16 - 基团。

9. 发明授权

US07786152B2 Compound 失效
标题翻译：复合
公开(公告)号：US07786152B2
公开(公告)日：2010-08-31
申请号：US11979160
申请日：2007-10-31
申请人： Nigel Vicker , Su Xiangdon , Dharshini Ganeshapillai , Atul Purohit , Michael John Reed , Barry Victor Lloyd Potter
发明人： Nigel Vicker , Su Xiangdon , Dharshini Ganeshapillai , Atul Purohit , Michael John Reed , Barry Victor Lloyd Potter
IPC分类号： A61K31/428
CPC分类号： C07D277/64 , C07D209/08 , C07D235/08 , C07D263/56 , C07D277/14 , C07D417/12
摘要： A compound having Formula I wherein one of R1 and R2 is a group of the formula wherein R4 is selected from H and hydrocarbyl, R5 is a hydrocarbyl group and L is an optional linker group, or R1 and R2 together form a ring substituted with the group wherein R3 is H or a substituent, and wherein X is selected from S, O, NR6 and C(R7)(R8), wherein R6 is selected from H and hydrocarbyl groups, wherein each of R7 and R8 are independently selected from H and hydrocarbyl groups.
摘要翻译：具有式I的化合物，其中R 1和R 2中的一个是下式的基团其中R 4选自H和烃基，R 5是烃基，L是任选的连接基团，或者R 1和R 2一起形成被其中R 3是H或取代基，其中X选自S，O，NR 6和C（R 7）（R 8），其中R 6选自H和烃基，其中R 7和R 8各自独立地选自H 和烃基。

10. 发明授权

US07230020B2 11β-hydroxysteroid dehydrogenase inhibitors 失效
标题翻译： 11beta-羟类固醇脱氢酶抑制剂
公开(公告)号：US07230020B2
公开(公告)日：2007-06-12
申请号：US10970064
申请日：2004-10-22
申请人： Nigel Vicker , Su Xiangdong , Dharshini Ganeshapillai , Atul Purohit , Michael John Reed , Barry Victor Lloyd Potter
发明人： Nigel Vicker , Su Xiangdong , Dharshini Ganeshapillai , Atul Purohit , Michael John Reed , Barry Victor Lloyd Potter
IPC分类号： A61K31/423 , A61K31/426 , C07D263/56 , C07D277/64
CPC分类号： C07D209/48 , C07D211/28 , C07D213/76 , C07D215/38 , C07D231/56 , C07D241/42 , C07D261/16 , C07D261/20 , C07D275/04 , C07D277/64 , C07D295/135 , C07D307/79 , C07D311/18 , C07D319/18 , C07D333/54 , C07D333/70 , C07D495/04
摘要： A compound having Formula I R1—Z—R2Formula I wherein R1 is an optionally substituted phenyl ring; R2 is or comprises an optionally substituted aromatic ring; and Z is —X—Y—L— or —Y—X—L— wherein either X is selected from —S(═O)(═O)— and —C(═O)—; and Y is —NR3—; or X is selected from —S(═O)(═O)— and —S—, and Y is —C(R4)(R5)—; L is an optional linker; and R3, R4 and R5 are each independently selected from H and hydrocarbyl; and wherein when R2 comprises the following structural moiety wherein Q is an atom selected from the group consisting of S, O, N and C; the compound is selected from compounds of the formulae R1—C(═O)—NR3—L—R2; R1—S(═O)(═O)—C(R4)(R5)—L—R2; R1—S—C(R4)(R5)—L—R2; R1—NR3—S(═O)(═O)—L—R2; R1—NR3—C(═O)—L—R2; R1—C(R4)(R5)—S(═O)(═O)—L—R2; and R1—C(R4)(R5)—S—L—R2.
摘要翻译：具有式I的化合物<？in-line-formula description =“In-line Formulas”end =“lead”？> R 1 -ZR 2式I < in-line-formula description =“In-line formula”end =“tail”？>其中R 1是任选取代的苯环; R 2是或包含任选取代的芳环; Z是-X-Y-L-或-Y-X-L-，其中X选自-S（-O）（ - O） - 和-C（-O） - ; 和Y是-NR 3 - ; 或者X选自-S（-O）（ - O） - 和-S-，Y是-C（R 4a）（R 5） - ; L是可选的接头; 和R 3，R 4和R 5各自独立地选自H和烃基; 并且其中当R 2包含以下结构部分时，其中Q是选自S，O，N和C的原子; 该化合物选自式R 1 -C（-O）-NR 3 -L-R 2的化合物; R 1 -S（-O）（ - O）-C（R 4）（R 5） - R L 2 / SUB>; R 1 -S-C（R 4）（R 5） - L-R 2; R 1 -SO 2 -S（-O）（ - O）-L-R 2; R 1 -NR 3 -C（-O）-L-R 2; R 1 -C（R 4）（R 5）-S（-O）（ - O）-LR 2， / SUB>; 和R 1 -C（R 4）（R 5）-S-L-R 2。

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