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    • 5. 发明申请
    • INTEGRATED DEVICE HAVING AN ARRAY OF PHOTODETECTORS AND AN ARRAY OF SAMPLE SITES
    • 具有照相机阵列和样品库阵列的集成设备
    • US20100230610A1
    • 2010-09-16
    • US12294469
    • 2007-03-20
    • Pieter Jan Van Der ZaagNigel David YoungHendrik Roelof Stapert
    • Pieter Jan Van Der ZaagNigel David YoungHendrik Roelof Stapert
    • G01J1/58B23P17/04
    • G01N21/6454G01N21/6428G01N21/76Y10T29/49826
    • An integrated device for detecting emissions from a sample (70) involves forming an array of photo detectors (20) for detecting the emissions and forming an array of sites for receiving the sample such that edges of the sites are defined by edges of the photo detectors. A side wall of a site using a diode can provide a side wall suitable for ink-jet printing samples such as biomolecules with no extra mask steps. This helps enable the sample and the photo detector to be mutually aligned more easily or more cost effectively than conventional devices where the site for receiving the sample is formed separately from the photo detector. The detection can be in any direction, such as lateral or vertical detection. Lateral optical detection with a shielded photodiode means only light emanating from one pixel/spot is detected. A light source (200) to stimulate emissions can be integrated.
    • 用于检测来自样品(70)的发射的集成装置涉及形成用于检测发射的光电检测器(20)的阵列,并形成用于接收样品的位置阵列,使得位置的边缘由光电检测器的边缘限定 。 使用二极管的位点的侧壁可以提供适合于喷墨打印样品的侧壁,例如没有额外掩模步骤的生物分子。 这有助于样品和光电检测器与传统的接收样品的部位与光电检测器分开形成的装置更容易或更经济地相互对准。 检测可以在任何方向,例如横向或垂直检测。 使用屏蔽光电二极管的横向光学检测意味着仅检测到从一个像素/点发出的光。 可以集成用于刺激排放物的光源(200)。
    • 7. 发明授权
    • Photodiode for detection within molecular diagnostics
    • 用于分子诊断中检测的光电二极管
    • US08399855B2
    • 2013-03-19
    • US12374000
    • 2007-07-05
    • Pieter Jan Van Der ZaagIan FrenchNigel David Young
    • Pieter Jan Van Der ZaagIan FrenchNigel David Young
    • G01N21/64
    • H01L31/1055G01N21/6428H01L31/103
    • A photodiode (200), for instance a PN or a PIN photodiode, is disclosed. The photodiode receives incident radiation having first and second spectral distributions, where the first spectral distribution is spectrally shifted from the second spectral distribution. The photodiode has a first semiconductor layer (211) capable of absorbing incident radiation (231) having a first spectral distribution without generating a photocurrent, while simultaneously transmitting incident radiation having a second spectral distribution to the intrinsic layer (212) for generating a photocurrent (213). The photodiode may be used in connection with detecting the presence of target molecules that has been labeled with labeling agents, such as fluorophores or quantum dots. The labeling agents are characterized by the Stokes shift and, therefore, they emit fluorescent radiation having the second spectral distribution that is spectrally shifted from the illumination radiation having the first spectral distribution.
    • 公开了一种光电二极管(200),例如PN或PIN光电二极管。 光电二极管接收具有第一和第二光谱分布的入射辐射,其中第一光谱分布从第二光谱分布光谱偏移。 光电二极管具有能够吸收具有第一光谱分布而不产生光电流的入射辐射(231)的第一半导体层(211),同时将具有第二光谱分布的入射辐射传输到本征层(212)以产生光电流 213)。 光电二极管可用于检测已经用标记试剂如荧光团或量子点标记的靶分子的存在。 标记试剂的特征在于斯托克斯位移,因此,它们发射具有与具有第一光谱分布的照射辐射光谱偏移的第二光谱分布的荧光辐射。