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1. 发明申请

US20050223111A1 Secure, standards-based communications across a wide-area network 审中-公开
标题翻译：安全的，基于标准的广域网通信
公开(公告)号：US20050223111A1
公开(公告)日：2005-10-06
申请号：US10982598
申请日：2004-11-04
申请人： Nehru Bhandaru , Michael Cook , Webster Gaidos , Susan Hares , Owais Hassan , Michael Carrafiello , Albert Lew , David Morris , Martin Mueller , Michael Vakulenko
发明人： Nehru Bhandaru , Michael Cook , Webster Gaidos , Susan Hares , Owais Hassan , Michael Carrafiello , Albert Lew , David Morris , Martin Mueller , Michael Vakulenko
IPC分类号： G06F20060101 , G06F15/16 , H04L12/46 , H04L12/56 , H04L29/06 , H04W12/08 , H04W80/02
CPC分类号： H04L63/0272 , H04L12/4604 , H04L12/4633 , H04L45/50 , H04L63/162 , H04L63/164 , H04W12/08 , H04W80/02
摘要： The invention includes systems and methods to extend security from enterprise networks to wide-area networks by allowing secure connectivity to the enterprise layer 2 network across a wide-area layer 3 network, such as the Internet
摘要翻译：本发明包括通过允许通过广域3网络（例如因特网）到企业层2网络的安全连接来将安全性从企业网络扩展到广域网的系统和方法

2. 外观设计

USD969231S1 Puzzle box 有权
公开(公告)号：USD969231S1
公开(公告)日：2022-11-08
申请号：US29633649
申请日：2018-01-15
申请人： David Morris
设计人： David Morris

3. 发明申请

US20070287182A1 METHOD AND APPARATUS FOR ANALYZING SOLUTIONS 有权
标题翻译：用于分析解决方案的方法和装置
公开(公告)号：US20070287182A1
公开(公告)日：2007-12-13
申请号：US11835567
申请日：2007-08-08
申请人： David Morris , Teresa Swanson
发明人： David Morris , Teresa Swanson
IPC分类号： G01N21/78 , G01N21/01
CPC分类号： G01N33/18 , G01N21/01 , G01N21/78 , G01N21/8483 , Y10T436/144444 , Y10T436/2575
摘要： An apparatus and method of analyzing an aqueous solution, as may be implemented with a hand-held portable electronic device (10). A test pad (32) responsive in color to a characteristic of an aqueous solution is interrogated by the device by measuring, in a plurality of wavelength ranges, intensity values of a test light as reflected off of the test strip. The intensity values may be expressed as values relative to intensities reflected off of white and black calibration surfaces. A relationship among the intensity values for the various wavelength ranges is developed through an algorithm that provides a ratio value that is responsive to the characteristic of the aqueous solution and that is non-responsive to absolute intensity values of the reflected light. The test pad may be supported on an opaque and non-reflective substrate (28) that cooperates with an opaque edge portion (14E) of a test element placement member (14B) and associated side walls (14W) of the device to minimize the impingement of ambient light onto the test pad during interrogation.
摘要翻译：一种分析水溶液的装置和方法，可以用手持便携式电子设备（10）实现。通过在多个波长范围内测量从测试条反射的测试光的强度值，通过测量器件询问在颜色上与水溶液的特性有关的测试垫（32）。强度值可以表示为相对于白色和黑色校准表面反射的强度的值。通过提供响应于水溶液的特性并且不响应于反射光的绝对强度值的比值的算法来开发各种波长范围的强度值之间的关系。测试垫可以被支撑在不透明和非反射衬底（28）上，该衬底与设备的测试元件放置构件（14B）的不透明边缘部分（14E）和相关联的侧壁（14W）配合，在询问期间最小化环境光在测试垫上的碰撞。

4. 发明申请

US20070212351A1 Novel therapeutic targets in cancer 失效
公开(公告)号：US20070212351A1
公开(公告)日：2007-09-13
申请号：US11257477
申请日：2005-10-24
申请人： David Morris , Marc Malandro
发明人： David Morris , Marc Malandro
IPC分类号： A61K31/70 , A61K38/02 , A61K39/395 , C12Q1/68
CPC分类号： C07K14/4748 , A61K39/00 , C12Q1/6886 , C12Q2600/106 , C12Q2600/136 , C12Q2600/16 , G01N33/57426 , G01N33/57492
摘要： The present invention relates to novel sequences for use in detection, diagnosis and treatment of cancers, especially lymphomas. The invention provides cancer-associated (CA) polynucleotide sequences whose expression is associated with cancer. The present invention provides CA polypeptides associated with cancer that are present on the cell surface and present novel therapeutic targets against cancer. The present invention further provides diagnostic compositions and methods for the detection of cancer. The present invention provides monoclonal and polyclonal antibodies specific for the CA polypeptides. The present invention also provides diagnostic tools and therapeutic compositions and methods for screening, prevention and treatment of cancer.

5. 发明申请

US20070093460A1 Methods of using selective 11beta-HSD inhibitors to treat gluocorticoid associated states 审中-公开
标题翻译：使用选择性11beta-HSD抑制剂治疗糖皮质激素相关状态的方法
公开(公告)号：US20070093460A1
公开(公告)日：2007-04-26
申请号：US11509181
申请日：2006-08-24
申请人： David Morris , Andrew Brem
发明人： David Morris , Andrew Brem
IPC分类号： A61K31/57 , A61K31/573
CPC分类号： A61K31/573 , A61K31/57 , A61K45/06 , A61K2300/00
摘要： Methods for treating glucocorticoid associated states using selective 11β-HSD1-dehydrogenase, 11β-HSD1-reductase and 11β-HSD2 dehydrogenase modulating compounds are described.
摘要翻译：描述了使用选择性11beta-HSD1-脱氢酶，11beta-HSD1-还原酶和11beta-HSD2脱氢酶调节化合物治疗糖皮质激素相关状态的方法。

6. 发明申请

US20060194210A1 Novel therapeutic targets in cancer 失效
公开(公告)号：US20060194210A1
公开(公告)日：2006-08-31
申请号：US10833833
申请日：2004-04-27
申请人： David Morris , Marc Malandro , Albert Lai , Christin Tse , Ali Fattaey
发明人： David Morris , Marc Malandro , Albert Lai , Christin Tse , Ali Fattaey
IPC分类号： C12Q1/68 , G01N33/574 , C07H21/04 , C12P21/06
CPC分类号： C07K14/4748 , C12Q1/6886 , C12Q2600/136
摘要： The present invention relates to novel sequences for use in detection, diagnosis and treatment of cancers, especially lymphomas. The invention provides cancer-associated (CA) polynucleotide sequences whose expression is associated with cancer. The present invention provides CA polypeptides associated with cancer that are present on the cell surface and present novel therapeutic targets against cancer. The present invention further provides diagnostic compositions and methods for the detection of cancer. The present invention provides monoclonal and polyclonal antibodies specific for the CA polypeptides. The present invention also provides diagnostic tools and therapeutic compositions and methods for screening, prevention and treatment of cancer.

7. 发明申请

US20060177861A1 Novel compositions and methods in cancer associated with altered expression of MCM3AP 审中-公开
标题翻译：与MCM3AP表达改变相关的癌症新型组合物和方法
公开(公告)号：US20060177861A1
公开(公告)日：2006-08-10
申请号：US11357638
申请日：2006-02-17
申请人： David Morris , Eric Engelhard
发明人： David Morris , Eric Engelhard
IPC分类号： C12Q1/68
CPC分类号： G01N33/574 , C07K14/47 , C12N9/1029 , C12Q1/6886 , C12Q2600/136 , C12Q2600/158 , G01N33/5011 , G01N2500/00
摘要： The present invention relates to novel sequences for use in diagnosis and treatment of carcinomas, especially breast cancers. In addition, the present invention describes the use of novel compositions for use in screening methods. The invention provides methods and compositioins associated with altered expression of MCM3AP.
摘要翻译：本发明涉及用于诊断和治疗癌症，特别是乳腺癌的新型序列。此外，本发明描述了用于筛选方法的新型组合物的用途。本发明提供了与改变的MCM3AP表达相关的方法和组合物。

8. 发明申请

US20060154250A1 Novel compositions and methods in cancer 审中-公开
标题翻译：癌症中的新型成分和方法
公开(公告)号：US20060154250A1
公开(公告)日：2006-07-13
申请号：US10539228
申请日：2003-12-15
申请人： David Morris , Marc Malandro
发明人： David Morris , Marc Malandro
IPC分类号： C12Q1/68 , G01N33/574 , C07H21/04 , C12P21/06 , C07K14/82 , C07K16/30
CPC分类号： C07K14/82 , C07K14/4748 , C12Q1/6886 , C12Q2600/136 , G01N33/5023 , G01N33/57415 , G01N33/57426 , G01N33/57434 , G01N33/5748
摘要： The present invention relates to novel sequences for use in detection, diagnosis and treatment of cancers, especially lymphomas. The invention provides cancer-associated (CA) polynucleotide sequences whose expression is associated with cancer. The present invention provides CA polypeptides associated with cancer and provides diagnostic compositions and methods for the detection of cancer. The present invention provides monoclonal and polyclonal antibodies specific for the CA polypeptides. The present invention also provides diagnostic tools and therapeutic compositions and methods for screening, prevention and treatment of cancer.
摘要翻译：本发明涉及用于癌症尤其是淋巴瘤的检测，诊断和治疗的新型序列。本发明提供癌症相关（CA）多核苷酸序列，其表达与癌症相关。本发明提供了与癌症相关的CA多肽，并提供了用于检测癌症的诊断组合物和方法。本发明提供对CA多肽具有特异性的单克隆和多克隆抗体。本发明还提供用于癌症的筛选，预防和治疗的诊断工具和治疗组合物和方法。

9. 发明申请

US20060142757A1 Apparatus and method for tissue resection 审中-公开
标题翻译：组织切除术的装置和方法
公开(公告)号：US20060142757A1
公开(公告)日：2006-06-29
申请号：US11335092
申请日：2006-01-18
申请人： Steven Daniel , David Morris
发明人： Steven Daniel , David Morris
IPC分类号： A61B18/14
CPC分类号： A61B18/1477 , A61B90/11 , A61B2018/0016 , A61B2018/00577 , A61B2018/1425 , A61B2018/143 , A61B2018/1475
摘要： A tissue ablation system is described that generates a uniform avascular plane of coagulated tissue to aid in the bloodless or near-bloodless resection of various biological tissues from a variety of organs. The tissue ablation system includes an energy director guide and two or more sets of bipolar energy directors. The energy director guide includes a series of channels that configure the energy directors to provide approximately uniform power distribution or current density through a target tissue volume or plane. The spacing among the channels of the energy director guide varies according to the total number of energy directors received in the energy director guide so that relative spacing among the center-most channels is largest and relative spacing among the end-most channels is smallest. The energy director guide secures a selected position of each of the energy directors in the target tissue volume.
摘要翻译：描述了组织消融系统，其产生凝固组织的均匀的无血管平面，以帮助来自各种器官的各种生物组织的无血或近无血的切除。组织消融系统包括能量导向器引导件和两组或多组双极能量引导器。能量导向器引导件包括一系列通道，其配置能量引导器以通过目标组织体积或平面提供近似均匀的功率分布或电流密度。能量导向器引导件的通道之间的间隔根据能量导向器引导器中接收到的能量引导器的总数而变化，使得最中心的通道之间的相对间隔最大，并且最终通道之间的相对间隔最小。能量导向器引导件将每个能量引导器的选定位置固定在目标组织体积中。

10. 发明申请

US20060134623A1 Novel compositions and methods in cancer 审中-公开
标题翻译：癌症中的新型成分和方法
公开(公告)号：US20060134623A1
公开(公告)日：2006-06-22
申请号：US10540903
申请日：2003-12-22
申请人： David Morris , Marc Malandro
发明人： David Morris , Marc Malandro
IPC分类号： C12Q1/68 , C07H21/04 , C12M1/34 , C12N15/63
CPC分类号： C07K16/30 , C07H21/04 , C12Q1/6837 , C12Q1/6886 , C12Q2600/106 , C12Q2600/136 , C12Q2600/158 , G01N33/5011 , G01N33/5017 , G01N33/57484
摘要： The present invention relates to novel sequences for use in detection, diagnosis and treatment of cancers, especially lymphomas. The invention provides cancer-associated (CA) polynucleotide sequences whose expression is dys-regulated in cancer tissues. The present invention provides CA polypeptides associated with cancer and provides diagnostic compositions and methods for the detection of cancer. The present invention provides monoclonal and polyclonal antibodies specific for the CA polypeptides. The present invention also provides diagnostic tools and therapeutic compositions and methods for screening, prevention and treatment of cancer.
摘要翻译：本发明涉及用于癌症尤其是淋巴瘤的检测，诊断和治疗的新型序列。本发明提供癌症相关（CA）多核苷酸序列，其表达在癌组织中被调节。本发明提供了与癌症相关的CA多肽，并提供了用于检测癌症的诊断组合物和方法。本发明提供对CA多肽具有特异性的单克隆和多克隆抗体。本发明还提供用于癌症的筛选，预防和治疗的诊断工具和治疗组合物和方法。

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