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1. 发明专利

JP2006282655A Lipid metabolism regulant 有权
标题翻译：脂肪代谢REGULANT
公开(公告)号：JP2006282655A
公开(公告)日：2006-10-19
申请号：JP2006024516
申请日：2006-02-01
申请人： National Food Research Institute , Nof Corp , 日本油脂株式会社 , 独立行政法人食品総合研究所
发明人： TANIMIZU KOICHI , ARAI MOTOHARU , IDE TAKASHI
IPC分类号： A61K31/045 , A23K1/16 , A23L1/30 , A61K9/16 , A61P1/16 , A61P3/06 , A61P3/10 , A61P9/00 , A61P19/02 , A61P43/00
摘要： PROBLEM TO BE SOLVED: To provide a lipid metabolism regulant useful for preventing or improving obesity and a fatty liver, capable of being widely utilized in pharmaceutical and food industries and, further, in animal feed and other industries, capable of inhibiting expression of a fatty acid synthetic enzyme group in a liver, capable of depressing activity thereof, and capable of decreasing amounts of triacylglycerol and cholesterol.
SOLUTION: This lipid metabolism regulant contains a 20-36C higher aliphatic alcohol as an active ingredient and depresses expression of a fatty acid synthetic enzyme, wherein a fatty acid synthetic enzyme comprises fatty acid synthase, glucose-6-phosphate dehydrogenase, ATP-citrate-lyase, malic enzyme, pyruvate kinase, and glycerol-3-phosphate acyltransferase. Further, the higher aliphatic alcohol is in a powdered state and has an average particle diameter of 1-150 μm.
COPYRIGHT: (C)2007,JPO&INPIT
摘要翻译：要解决的问题：提供可用于预防或改善肥胖和脂肪肝的脂质代谢调节剂，其能够广泛地用于制药和食品工业，以及能够抑制表达的动物饲料和其它工业中的肝脏中的脂肪酸合成酶基团，能够抑制其活性，并且能够降低三酰基甘油和胆固醇的量。解决方案：该脂质代谢调节剂含有20-36℃高级脂肪醇作为活性成分，并抑制脂肪酸合成酶的表达，其中脂肪酸合成酶包括脂肪酸合酶，葡萄糖-6-磷酸脱氢酶，ATP - 柠檬酸裂解酶，苹果酸酶，丙酮酸激酶和甘油-3-磷酸酰基转移酶。此外，高级脂肪族醇为粉末状，平均粒径为1-150μm。版权所有（C）2007，JPO＆INPIT

2. 发明专利

JP2004217633A Method of producing higher alcohol 有权
公开(公告)号：JP2004217633A
公开(公告)日：2004-08-05
申请号：JP2003423759
申请日：2003-12-19
申请人： Nof Corp , 日本油脂株式会社
发明人： TANIMIZU KOICHI , ABE SHUICHI , IWANAMI KOICHI
IPC分类号： A23L1/30 , A23L1/03 , C07C27/02 , C07C29/86 , C07C31/02 , C11B11/00 , C11C1/04
摘要： PROBLEM TO BE SOLVED: To provide a method of producing higher alcohol in which natural wax is saponified into a long-chain fatty acid soap and a higher alcohol, then the higher alcohol is extracted with a fat and oil melting at ≤ 30°C as a solvent and the long chain fatty acid soap is washed with warm water, thus the resultant higher alcohol is sanitarily desirable with high safety. SOLUTION: In this method of producing higher alcohol, natural wax including higher alcohol with a carbon atoms of 20-36 as constitution components is saponified into a long chain fatty acid soap and a higher alcohol, the higher alcohol of 20-36C is extracted with a solvent and fractionated. In this case, a fat and oil melting at ≤ 30°C is used as a solvent to extract the higher alcohol melting at ≥ 55°C, then the extracted higher alcohol is washed with hot water at ≥ 55°C to separate the long chain fatty acid soap whereby the purified higher alcohol is collected. COPYRIGHT: (C)2004,JPO&NCIPI

3. 发明专利

JP2004123636A Doubly coated granule and method for producing the same 审中-公开
公开(公告)号：JP2004123636A
公开(公告)日：2004-04-22
申请号：JP2002291711
申请日：2002-10-03
申请人： Nof Corp , 日本油脂株式会社
发明人： TANIMIZU KOICHI , MIYAMOTO ITARU , KATO HIROSHI
IPC分类号： A23L1/302 , A23L1/00 , A23P1/08 , A61K9/16 , A61K31/525 , A61K47/36 , A61K47/42 , A61K47/44 , A61P1/02 , A61P17/08 , A61P27/02
摘要： PROBLEM TO BE SOLVED: To provide a doubly coated granule which has ≤2 mm particle diameter and with which the internal absorption of water-soluble vitamins is improved. SOLUTION: The doubly coated granule comprises (A) a core material of one or more kinds selected from the group of the water-soluble vitamins having ≤2 mm particle diameter and consisting of vitamin C, vitamin B1, vitamin B2, vitamin B6, vitamin B12, niacin, folic acid, pantothenic acid and biotin, (B) the first coating material of one or more kinds selected from an alcohol-soluble protein comprising zein and gluten, a thickening and stabilizing agent comprising pullulan, gelatin, xanthan gum, gum arabic and sodium caseinate, and a material of a gelatinizing agent comprising agar, gellan gum and carrageenan and exhibiting slightly water-soluble property at normal temperature, and (C) the second coating material of a hardened oil having ≥40°C melting point. The doubly coated granule is obtained by coating the core material of the component A with the first coating material of the component B, and further coating the coated product with the second coating material of the component C so as to form the most outer layer. COPYRIGHT: (C)2004,JPO

4. 发明专利

JP2007191425A Production method of ubidecarenone-containing powder 审中-公开
标题翻译：含有贝他酮的粉末的生产方法
公开(公告)号：JP2007191425A
公开(公告)日：2007-08-02
申请号：JP2006010933
申请日：2006-01-19
申请人： Nof Corp , 日本油脂株式会社
发明人： TANIMIZU KOICHI , MIYAZAKI ATSUNORI , SATO TOSHIHIRO
IPC分类号： A61K31/122 , A61K9/14 , A61K9/20 , A61K47/10 , A61K47/42
摘要： PROBLEM TO BE SOLVED: To provide a production method of a highly ubidecarenone-containing powder and the powder obtained thereby; for details, a method of producing, with a high production efficiency, a powder containing ubidecarenone with high concentration and excellent in compression moldability, filling property, and flowability.
SOLUTION: A ubidecarenone dispersion liquid comprising (A) 100 pts.mass ubidecarenone, (B) 5-70 pts.mass prolamine protein, and (C) 250-1,000 pts.mass water-containing ethanol with a moisture content of 10-60 mass% is sprayed on a prolamine protein powder with a bulk density of 0.1-0.5 g/cm
3 and fluidized in a fluid bed apparatus.
COPYRIGHT: (C)2007,JPO&INPIT
摘要翻译：要解决的问题：提供一种高度含ubidecarenone的粉末的制备方法和由此获得的粉末; 详细地说，以高生产率生产含有高浓度的ubidecarenone的粉末和压缩成型性，填充性和流动性优异的方法。解决方案：包含（A）100质量份ubidecarenone，（B）5-70盎司谷醇溶蛋白和（C）250-1,000盎司含水乙醇的二颊含烯分散液，水分含量为将10-60质量％喷洒在体积密度为0.1-0.5g / cm 3的蛋氨酸蛋白粉末上，并在流化床装置中流化。版权所有（C）2007，JPO＆INPIT

5. 发明专利

JP2007091672A Adiponectin-raising agent 审中-公开
标题翻译：亚硝酸盐提取剂
公开(公告)号：JP2007091672A
公开(公告)日：2007-04-12
申请号：JP2005285441
申请日：2005-09-29
申请人： Nof Corp , 日本油脂株式会社
发明人： TANIMIZU KOICHI , TANAKA YUKIHISA
IPC分类号： A61K31/045 , A23L1/30 , A61P3/04 , A61P3/06 , A61P3/10 , A61P9/12 , A61P43/00
摘要： PROBLEM TO BE SOLVED: To provide an adiponectin-raising agent capable of maintaining a biological factors closely involving so-called lifestyle-related diseases such as hypertension, obesity, hyperlipidemia and diabetes mellitus into a normal values, and foods containing the adiponectin-raising agent, capable of lowering insulin and glucose and capable of maintaining a biological factors closely involving so-called life-style related diseases such as hypertension, obesity, hyperlipidemia and diabetes mellitus into a normal values. SOLUTION: The adiponectin-raising agent comprises a 22-36C higher aliphatic alcohol as an active ingredient. The foods capable of raising adiponectin comprises each a 22-36C higher aliphatic alcohol as an active ingredient. COPYRIGHT: (C)2007,JPO&INPIT
摘要翻译：要解决的问题：提供能够将密切涉及所谓的生活方式相关疾病如高血压，肥胖，高脂血症和糖尿病的生物因子保持在正常值的脂联素生成剂，以及含有脂联素的食品能够降低胰岛素和葡萄糖并且能够将紧密地涉及所谓的生活方式相关疾病如高血压，肥胖，高脂血症和糖尿病的生物因子维持在正常值。解决方案：脂连蛋白生成剂包含22-36℃高级脂肪醇作为活性成分。能够提高脂联素的食物包含22-36℃的高脂肪醇作为活性成分。版权所有（C）2007，JPO＆INPIT

6. 发明专利

JP2004175713A Coated oligosaccharide powder, molded form thereof and method for producing the molded form 审中-公开
公开(公告)号：JP2004175713A
公开(公告)日：2004-06-24
申请号：JP2002343187
申请日：2002-11-27
申请人： Nof Corp , 日本油脂株式会社
发明人： MIYAZAKI ATSUNORI , TANIMIZU KOICHI
IPC分类号： A23L1/30 , A23L1/09 , A61K9/26 , A61K9/56 , A61K31/7016 , A61K31/702 , A61K35/74 , A61K47/44 , A61P1/12 , A61P37/04 , C07H3/04 , C07H3/06
摘要： PROBLEM TO BE SOLVED: To provide oligosaccharide powder compression-moldable with substantially no tableting trouble through directly mixing an oligosaccharide powder material, giving a molded form suppressed in long-term hygroscopicity and rich in oligosaccharides, and to provide a compression-molded form using the powder. SOLUTION: The oligosaccharide powder 10-500μm in mean particle size comprises 20-94 wt.% of oligosaccharides(a1) as the core material and 6-80 wt.% of an oily component(a2) ≥40°C in melting point as the coat. The compression-molded oligosaccharide form comprises 10-94 pts. wt. of the coated oligosaccharide powder( A-component ), 5-90 pts. wt. of a vehicle( B-component ) and 0.01-10 pts. wt. of a lubricant( C-component ), containing 10-70 pts. wt. of the oligosaccharides on a genuine basis. COPYRIGHT: (C)2004,JPO

7. 发明专利

JP2007135516A Propolis powder coated product and method for producing the same, and propolis-containing food product 审中-公开
标题翻译：丙烯酸粉末涂料产品及其生产方法和含有食品的产品
公开(公告)号：JP2007135516A
公开(公告)日：2007-06-07
申请号：JP2005336012
申请日：2005-11-21
申请人： Api Co Ltd , Nof Corp , アピ株式会社 , 日本油脂株式会社
发明人： TANIMIZU KOICHI , YOSHIMURA KAZUNORI , SATO CHIKAFUMI , TAZAWA SHIGEMI
IPC分类号： A23L1/076 , A23L1/30
摘要： PROBLEM TO BE SOLVED: To provide a propolis powder coated product which prevents the deterioration of useful ingredients derived from propolis and is excellent in temporal stability, to provide a method for producing the same, and to provide a propolis-containing food product. SOLUTION: The propolis powder coated product has a fat-based coating layer having a melting point of 40°C on the surfaces of propolis powder particles. The propolis powder particle has a structure produced by coating the surface of propolis powder with the powder of propolis water extract or with esterified starch. The propolis powder is preferably composed of the powder of a propolis alcohol extract. The method for producing the propolis powder coated product comprises a process for coating the surface of the propolis powder with the powder of a propolis water extract or with esterified starch to prepare the propolis powder particles, and a process for mixing and stirring the propolis powder particles with fatty coating material having an average particle diameter of 0.1 to 50 μm at an impact average load of 0.01 to 10N. A propolis-containing food product contains the propolis powder coated product. COPYRIGHT: (C)2007,JPO&INPIT
摘要翻译：要解决的问题：提供蜂胶粉末涂布产品，其防止由蜂胶衍生的有用成分的劣化，并且具有优异的时间稳定性，提供其制备方法，并提供含蜂胶的食品。解决方案：蜂胶粉末涂层产品在蜂胶粉末颗粒表面上具有熔点为40℃的脂肪基涂层。蜂胶粉末颗粒具有通过用蜂胶水提取物或酯化淀粉粉末涂布蜂胶粉末的表面而制备的结构。蜂胶粉末优选由蜂胶醇提取物的粉末组成。制备蜂胶粉末涂布产品的方法包括用蜂胶水提取物粉末或酯化淀粉涂覆蜂胶粉末表面以制备蜂胶粉末的方法，以及将蜂胶粉末颗粒混合和搅拌的方法在0.01〜10N的冲击平均负荷下，平均粒径为0.1〜50μm的脂肪类涂料。含蜂胶的食品含有蜂胶粉末涂层产品。版权所有（C）2007，JPO＆INPIT

8. 发明专利

JP2007063203A Diabetes-ameliorating agent 审中-公开
标题翻译：糖尿病患者
公开(公告)号：JP2007063203A
公开(公告)日：2007-03-15
申请号：JP2005252774
申请日：2005-08-31
申请人： Nof Corp , 日本油脂株式会社
发明人： TANIMIZU KOICHI , TANAKA YUKIHISA
IPC分类号： A61K31/045 , A23L1/30 , A61P3/10
摘要： PROBLEM TO BE SOLVED: To provide a safe diabetes-ameliorating agent usable for a long period because a higher alcohol reduces blood glucose level and insulin of a rat model of type II diabetes, and increases an amount of adiponectin, and thereby the higher alcohol is effective for amelioration of an insulin-independent diabetes (type II diabetes).
SOLUTION: The diabetes-ameliorating agent contains a 22-36C higher alcohol as an active ingredient. The diabetes-ameliorating food contains the 22-36C higher alcohol. The 22-36C higher alcohol of 10 mg to 10 g is orally administered per day in the diabetes-ameliorating agent.
COPYRIGHT: (C)2007,JPO&INPIT
摘要翻译：要解决的问题：为了提供长期使用的安全的糖尿病改善剂，因为高级醇降低II型糖尿病大鼠模型的血糖水平和胰岛素，并且增加脂连蛋白的量，从而使高级酒精对于改善胰岛素不依赖性糖尿病（II型糖尿病）是有效的。解决方案：糖尿病改善剂含有22-36℃高级醇作为活性成分。糖尿病改善食物含有22-36℃的高酒精。在糖尿病改善剂中每天口服10mg至10g的22-36℃高级醇。版权所有（C）2007，JPO＆INPIT

9. 发明专利

JP2006213601A Ubidecarenone-containing powdery meterial and method for producing the same 审中-公开
标题翻译：含有贝他酮的含量粉剂及其制造方法
公开(公告)号：JP2006213601A
公开(公告)日：2006-08-17
申请号：JP2005025238
申请日：2005-02-01
申请人： Nof Corp , 日本油脂株式会社
发明人： TANIMIZU KOICHI , MIYAZAKI ATSUNORI , IWANAMI KOICHI
IPC分类号： A61K31/122 , A23L1/30 , A61K9/14 , A61K9/20 , A61K47/42 , A61P3/02
摘要： PROBLEM TO BE SOLVED: To provide a ubidecarenone-containing powdery material and a method for producing the same, and as further more details, the powdery material containing the ubidecarenone in a high concentration, excellent in tablet-forming property, filling property and fluidity, and produced in a good production efficiency. SOLUTION: This ubidecarenone-containing powdery material having 50-500 μm mean particle diameter is provided by mixing (A component) 30-80 mass% ubidecarenone powder with (B component) 70-20 mass% excipient while fluidizing in a fluidized bed device, and spraying (C component) 10-50 pts.mass ratio prolamine protein in a solution state based on 100 pts.mass total of the A and B components. COPYRIGHT: (C)2006,JPO&NCIPI
摘要翻译：要解决的问题：提供含有ubidecarenone的粉末状材料及其制造方法，更详细地说，含有高浓度的ubidecarenone的粉末状材料，成型性能优异，填充性流动性好，生产效率高。解决方案：通过将（A成分）30-80质量％的ubidecarenone粉末与（B成分）的70-20质量％的赋形剂混合，同时在流化床中流化而提供含有平均粒径为50-500μm的含ubidecarenone的粉末状材料床装置和喷雾（C组分）10-50质量比的醇溶蛋白溶液在溶液状态下，基于100磅的A和B组分。版权所有（C）2006，JPO＆NCIPI

10. 发明专利

JP2009084157A Method for producing oil and fat-coated powder 审中-公开
标题翻译：生产油和脂肪涂层粉末的方法
公开(公告)号：JP2009084157A
公开(公告)日：2009-04-23
申请号：JP2007251539
申请日：2007-09-27
申请人： Nof Corp , 日油株式会社
发明人： TANIMIZU KOICHI , SATO TOSHIHIRO
IPC分类号： A61K47/42 , A23D9/00 , A23L1/00 , A23L1/22 , A61K9/14 , B01J2/00 , B01J2/10
摘要： PROBLEM TO BE SOLVED: To provide a method for producing an oils and fats-coated powder covering taste components sufficiently, and excellent in masking effect, taste, tablet-forming property and also in preservation stability. SOLUTION: This method for producing the oils and fats-covered powder containing the taste components comprises the following (A) to (C) processes. (A) A process of covering zein on the powder containing the taste components. (B) A process of obtaining the covered powder by colliding hydrogenated oils and fats powder having 1 to 50 μm mean particle diameter, 50 to 80°C melting point and ≤0.6 peak intensity ratio (19°/21° intensity ratio) of the peak intensity at 2θ (19°) to the peak intensity at 2θ (21°) in X-ray diffraction measurements by using CuKα beam as a light source to the zein-coated powder in a condition that the powder temperature becomes ≤45°C. (C) A process of tempering the covered powder prepared by the above process (B) at 35 to 60°C for 1 to 200 hr. COPYRIGHT: (C)2009,JPO&INPIT
摘要翻译：要解决的问题：提供一种充分覆盖味道成分的油脂和油脂粉末的制造方法，掩蔽效果，味道，片剂形成性以及保存稳定性优异的方法。解决方案：用于生产含有味道成分的油和脂肪覆盖的粉末的方法包括以下（A）至（C）方法。（A）在含有味道成分的粉末上覆盖玉米醇溶蛋白的方法。（B）通过使氢化油与平均粒径为1〜50μm，熔点为50〜80℃，峰强度比（强度比为19°/ 21°）的粉末粉末相比，获得被覆粉末的方法在粉末温度变为≤45℃的条件下，通过使用CuKα光束作为玉米蛋白包被粉末的光源，在X射线衍射测定中，在2θ（19°）与2θ（21°）的峰强度下的峰强度。（C）将上述方法（B）制备的被覆粉末在35〜60℃下回火1〜200小时的方法。版权所有（C）2009，JPO＆INPIT

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