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1. 发明专利

JP2012005888A Charged particle beam irradiation apparatus 有权
标题翻译：充电颗粒光束辐射装置
公开(公告)号：JP2012005888A
公开(公告)日：2012-01-12
申请号：JP2011223669
申请日：2011-10-11
申请人： National Cancer Center , Sumitomo Heavy Ind Ltd , 住友重機械工業株式会社 , 独立行政法人国立がん研究センター
发明人： NISHIO TEIJI , OGINO TAKASHI , NOMURA KAZUHIRO , TACHIKAWA TOSHIKI
IPC分类号： A61N5/10
摘要： PROBLEM TO BE SOLVED: To provide a charged particle beam irradiation apparatus improved in accuracy of positioning a body to be irradiated in an irradiation chamber.SOLUTION: This charged particle beam irradiation apparatus includes: a rotary gantry 103 constituting the irradiation chamber; a charged particle beam irradiation section 1 mounted on the rotary gantry 103 and being rotatable about a mounting base 105; and a detector 30 for detecting gamma rays generated from a body 51 to be irradiated. The detector 30 is movable in the direction of a rotation axis X of the rotary gantry 103 and is storable on the back face side with respect to the back panel of the rotary gantry 103.
摘要翻译：要解决的问题：提供一种提高在照射室中照射的身体的定位精度的带电粒子束照射装置。该带电粒子束照射装置包括：构成照射室的旋转台架103; 安装在旋转台架103上并可绕安装基座105旋转的带电粒子束照射部分1; 以及检测器30，用于检测从被照射的主体51产生的伽马射线。检测器30能够在旋转台架103的旋转轴线X的方向上移动，并相对于旋转台架103的背面板保存在背面侧。（C）2012，JPO＆INPIT

2. 发明专利

JP2011194243A Charged particle beam irradiation apparatus 有权
标题翻译：充电颗粒光束辐射装置
公开(公告)号：JP2011194243A
公开(公告)日：2011-10-06
申请号：JP2011103181
申请日：2011-05-02
申请人： National Cancer Center , Sumitomo Heavy Ind Ltd , 住友重機械工業株式会社 , 独立行政法人国立がん研究センター
发明人： NISHIO TEIJI , OGINO TAKASHI , NOMURA KAZUHIRO , TACHIKAWA TOSHIKI
IPC分类号： A61N5/10 , A61B6/00 , G01T1/161 , G01T1/29 , G21K5/00 , G21K5/04
CPC分类号： A61B6/506
摘要： PROBLEM TO BE SOLVED: To provide a charged particle beam irradiation apparatus improved in positioning accuracy of an object to be irradiated in an irradiation room.SOLUTION: In an irradiation room 103, annihilation γ-ray generated from a position where a radiopharmaceutical injected into an object 51 to be irradiated reaches, is detected to detect an irradiation target position being the destination of the radioactive medicament, and also annihilation γ-ray from positron emission nuclei generated by a nuclear reaction between the charged particle beam irradiated to the object 51 to be irradiated and nuclei in the object 51 to be irradiated are detected to detect a position where the charged particle beam practically reaches. Thus, in the irradiation room 103, a position displacement between the irradiation target position and the position where the charged particle beam practically reaches can be corrected by confirming an irradiation target position and a position where the charged particle beam practically reaches, so that the object 51 to be irradiated is positioned at a suitable position.
摘要翻译：要解决的问题：提供一种提高照射室内要被照射物体的定位精度的带电粒子束照射装置。解决方案：在照射室103中，从放射性药剂注入的放射线药物的位置产生的湮灭γ射线被检测出的物体51被检测为检测作为放射性药剂的目的地的照射目标位置，还可以将照射到被检体51的带电粒子束之间的核反应产生的正电子发射核湮灭为γ射线检测待照射物体51中的照射和核，以检测带电粒子束实际达到的位置。因此，在照射室103中，可以通过确认照射目标位置和带电粒子束实际达到的位置来校正照射目标位置与带电粒子束实际达到的位置之间的位置偏移，使得物体 51被照射在适当的位置。

3. 发明专利

JP2012005889A Charged particle beam irradiation apparatus 有权
标题翻译：充电颗粒光束辐射装置
公开(公告)号：JP2012005889A
公开(公告)日：2012-01-12
申请号：JP2011223670
申请日：2011-10-11
申请人： National Cancer Center , Sumitomo Heavy Ind Ltd , 住友重機械工業株式会社 , 独立行政法人国立がん研究センター
发明人： NISHIO TEIJI , OGINO TAKASHI , NOMURA KAZUHIRO , TACHIKAWA TOSHIKI
IPC分类号： A61N5/10
摘要： PROBLEM TO BE SOLVED: To provide a charged particle beam irradiation apparatus improved in accuracy of positioning a body to be irradiated in an irradiation chamber.SOLUTION: The charged particle beam irradiation apparatus includes: a rotary gantry 103 constituting the irradiation chamber; a charged particle beam irradiation section 1 mounted on the rotary gantry 103 and being rotatable about a mounting base 105; and a detector 30 for detecting gamma rays generated from a body 51 to be irradiated. The detector 30 is mounted on the rotary gantry 103 and rotatable about the mounting base 105.
摘要翻译：要解决的问题：提供一种提高在照射室中照射的身体的定位精度的带电粒子束照射装置。带电粒子束照射装置包括：构成照射室的旋转台架103; 安装在旋转台架103上并可绕安装基座105旋转的带电粒子束照射部分1; 以及检测器30，用于检测从被照射的主体51产生的伽马射线。检测器30安装在旋转台架103上并可围绕安装基座105旋转。版权所有：（C）2012，JPO＆INPIT

4. 发明专利

JP2011217880A Simulation device for charged particle beam amount, irradiation device of charged particle beam, simulation method for charged particle beam amount, and irradiation method of charge particle beam 有权
标题翻译：充电颗粒束的模拟装置，充电颗粒束的辐射装置，充电颗粒束的模拟方法和充电颗粒光束的辐射方法
公开(公告)号：JP2011217880A
公开(公告)日：2011-11-04
申请号：JP2010088532
申请日：2010-04-07
申请人： National Cancer Center , Sumitomo Heavy Ind Ltd , 住友重機械工業株式会社 , 独立行政法人国立がん研究センター
发明人： NISHIO TEIJI , ETO YUSUKE , YAMADA MANABU
IPC分类号： A61N5/10
摘要： PROBLEM TO BE SOLVED: To provide a simulation device and simulation method for charged particle beam amount, which allow early determination of a dose distribution of charged particle beam with a reduced load on arithmetic processing while suppressing the deterioration of accuracy.SOLUTION: The simulation device 3 includes: an input unit 31 which receives input of simulation data including material information of an irradiation object X and irradiation information of proton beam B; and an arithmetic unit 33 which determines a dose distribution of the proton beam B within the irradiation object X based on the simulation data received by the input unit 31 and a dose distribution kernel. The arithmetic unit 33 forms a Surface Map from the proton beam B assumed to reach the body surface, breaks down the Surface Map to break down the proton beam B into a plurality of beamlets Ba, and determines the dose distribution of the proton beam B within the irradiation body X based on the simulation data received by the input unit 31 and the plurality of beamlets Ba.
摘要翻译：要解决的问题：提供一种用于带电粒子束量的模拟装置和模拟方法，其允许在抑制精度劣化的同时，在运算处理中尽早确定带负载的粒子束的负载的剂量分布。模拟装置3包括：输入单元31，其接收包括照射对象X的材料信息和质子束B的照射信息的模拟数据的输入; 以及算术单元33，其基于由输入单元31和剂量分布核心接收的模拟数据来确定辐射对象X内的质子束B的剂量分布。算术单元33从假设为达到体表的质子束B形成表面图，将表面图分解，将质子束B分解为多个子束Ba，并确定质子束B的剂量分布照射体X基于由输入单元31接收的模拟数据和多个子束Ba。版权所有（C）2012，JPO＆INPIT

5. 发明专利

JP2010218886A Charged particle beam irradiation control device, and charged particle beam irradiation method 有权
标题翻译：充电颗粒光束辐射控制装置和充电颗粒光束辐射方法
公开(公告)号：JP2010218886A
公开(公告)日：2010-09-30
申请号：JP2009064295
申请日：2009-03-17
申请人： National Cancer Center , Sumitomo Heavy Ind Ltd , 住友重機械工業株式会社 , 独立行政法人国立がん研究センター
发明人： NISHIO TEIJI , TACHIKAWA TOSHIKI
IPC分类号： H05H13/00
摘要： PROBLEM TO BE SOLVED: To provide a charged particle beam irradiation control device for quickening the change-over of charged particle beams between irradiated and non-irradiated conditions while stabilizing the charged particle beams to be emitted, and to provide a charged particle beam irradiation method.
SOLUTION: Accelerating voltage in the irradiated condition of the charged particle beams is set as reference accelerating voltage, and the accelerating voltage is changed over into set accelerating voltage which is higher or lower than the reference accelerating voltage. Thereby, the track of the charged particle beams is changed to make the charged particle beams R0 collide on another object into the non-irradiated condition. Since the non-irradiated condition can be established only by changing over the accelerating voltage to be higher or lower, the change-over between the irradiated and non-irradiated conditions can be quickened. Since there is no need for ON/OFF control of arc discharge of an ion source 21, the charged particle beams can be stabilized without being influenced by the instable rise of the arc discharge.
COPYRIGHT: (C)2010,JPO&INPIT
摘要翻译：要解决的问题：提供一种带电粒子束照射控制装置，用于在稳定被发射的带电粒子束的同时，加快照射和非照射条件之间的带电粒子束的转换，并提供带电粒子光束照射法。解决方案：将带电粒子束的照射状态下的加速电压设定为基准加速电压，将加速电压切换为高于或低于基准加速电压的设定加速电压。由此，使带电粒子束的轨迹变化，使带电粒子束R0与另一物体碰撞成非照射状态。由于仅通过将加速电压切换为更高或更低才能建立无照射状态，因此可以加快照射和未照射条件之间的转换。由于不需要对离子源21的电弧放电进行ON / OFF控制，所以可以不受电弧放电的不稳定上升的影响而稳定带电粒子束。版权所有（C）2010，JPO＆INPIT

6. 发明专利

JP2014018525A Image processing device and program 有权
标题翻译：图像处理设备和程序
公开(公告)号：JP2014018525A
公开(公告)日：2014-02-03
申请号：JP2012161830
申请日：2012-07-20
申请人： National Cancer Center , 独立行政法人国立がん研究センター , Keen Medical Physics:Kk , 株式会社Keenメディカルフィジックス
发明人： NISHIO TEIJI , MIYATAKE AYA
IPC分类号： A61N5/10
摘要： PROBLEM TO BE SOLVED: To provide an image processing device for supporting recognition of a temporal change in activated biological tissue.SOLUTION: The image processing device repeatingly acquires an activated tissue image representing the position of biological tissue activated by a particle beam treatment device at each predetermined timing, relatively moving a plurality of activated tissue images acquired at different timing as comparison objects for positioning so as to meet reference positions with each other in a predetermined organism, and generates a contrast image by using the plurality of positioned activated tissue images as the comparison objects. The image processing device displays the generated image.
摘要翻译：要解决的问题：提供一种用于支持活化的生物组织的时间变化的识别的图像处理装置。解决方案：图像处理装置重复地获取代表由每个粒子束处理装置激活的生物组织的位置的激活的组织图像相对移动在不同时刻获取的多个激活的组织图像作为比较对象进行定位，以便在预定生物体中彼此满足参考位置，并且通过使用多个定位的激活的组织图像作为对象图像，生成对比度图像比较对象。图像处理装置显示生成的图像。

7. 发明专利

JP2013048713A Image generation apparatus, method, and program 有权
标题翻译：图像生成装置，方法和程序
公开(公告)号：JP2013048713A
公开(公告)日：2013-03-14
申请号：JP2011188117
申请日：2011-08-31
申请人： Cybernet Systems Co Ltd , サイバネットシステム株式会社 , National Cancer Center , 独立行政法人国立がん研究センター
发明人： NISHIO TEIJI , NAKAI YOICHI
IPC分类号： A61B6/03
摘要： PROBLEM TO BE SOLVED: To provide a technology allowing deletion of an artifact from a CT (Computed Tomography) image, and reproduction of CT values of that portion.SOLUTION: An input part (11) inputs a first image captured by imaging an imaging target with first X-rays, and a second image not having the artifact corresponding to the first image. An artifact region estimation part (17) divides the first image into an artifact region and a non-artifact region, and estimates a pixel value when the artifact is absent about each pixel of the artifact region in the first image based on the pixel value of each pixel of a region corresponding to the artifact region in the second image and correlation between pixel values obtained by the imaging by the first X-rays and pixel values of the second image. An image correction part (19) composes the data on the estimated pixel value of each pixel of the artifact region and the data on the pixel value of each pixel of the non-artifact region of the first image to generate a repaired image.
摘要翻译：要解决的问题：提供允许从CT（计算机断层扫描）图像中删除伪影的技术，以及该部分的CT值的再现。输入部分（11）通过用第一X射线对成像目标进行成像而获取的第一图像和不具有与第一图像相对应的伪像的第二图像输入。伪像区域估计部分（17）将第一图像划分成伪影区域和非伪像区域，并且当第一图像中的伪像区域的每个像素不存在伪像时，基于像素值对应于第二图像中的伪影区域的区域的每个像素以及通过第一X射线的成像获得的像素值与第二图像的像素值之间的相关性。图像校正部件（19）构成关于伪影区域的每个像素的估计像素值的数据和关于第一图像的非伪像区域的每个像素的像素值的数据，以生成修复的图像。版权所有（C）2013，JPO＆INPIT

8. 发明专利

JP2014052919A Image generation device and program 有权
标题翻译：图像生成设备和程序
公开(公告)号：JP2014052919A
公开(公告)日：2014-03-20
申请号：JP2012197917
申请日：2012-09-07
申请人： National Cancer Center , 独立行政法人国立がん研究センター
发明人： NISHIO TEIJI
IPC分类号： G06T15/08 , G06T19/00
CPC分类号： G06T15/08 , G06T7/12 , G06T11/008 , G06T2207/10072 , G06T2207/10081 , G06T2207/20104 , G06T2210/41 , G06T2211/416
摘要： PROBLEM TO BE SOLVED: To provide an image generation device capable of generating the image of a target region cut out along an arbitrary section.SOLUTION: Reconfigured image voxel data in a three-dimensional space is received, the designation of two-dimensional target regions is received on the plurality of sections of the image voxel data and, based on each of the designated two-dimensional target regions, at least one three-dimensional target region is generated corresponding to the two-dimensional target region in the three-dimensional space. By using target region voxel data having a voxel value varied corresponding to the received image voxel data and based on at least which one of the three-dimensional regions it is included, a contour line is generated. The contour line is drawn together with the image voxel data included in a defined surface.
摘要翻译：要解决的问题：提供能够产生沿着任意部分切出的目标区域的图像的图像生成装置。解决方案：接收三维空间中的重新配置的图像体素数据，二维目标区域的指定被接收在图像体素数据的多个部分上，并且基于每个指定的二维目标区域，对应于三维空间中的二维目标区域生成至少一个三维目标区域。通过使用具有对应于接收到的图像体素数据而变化的体元值的目标区域体元数据，并且基于包括其中的至少哪一个三维区域，生成轮廓线。轮廓线与包含在限定表面中的图像体素数据一起绘制。

9. 发明专利

JP2014052318A Positron emission nucleus position detection device 有权
标题翻译： POSITRON排放核子位置检测装置
公开(公告)号：JP2014052318A
公开(公告)日：2014-03-20
申请号：JP2012197915
申请日：2012-09-07
申请人： National Cancer Center , 独立行政法人国立がん研究センター , Keen Medical Physics:Kk , 株式会社Keenメディカルフィジックス
发明人： NISHIO TEIJI , MIYATAKE AYA
IPC分类号： G01T1/161
摘要： PROBLEM TO BE SOLVED: To provide a positron emission nucleus position detection device capable of improving estimation precision of a presence position and a range of three-dimensional positron decay nucleus.SOLUTION: A positron emission nucleus position detection device includes: a pair of first detectors which have a pair of planes arranged across an object to be irradiated with a particle beam, and detect γ-rays in the planes; a second detector which is arranged in a direction different from the first detectors with respect to the object to be irradiated, and detects an incidence direction of the γ-rays; and estimation means of estimating the emission position of the γ-rays, that the second detector detects in the object to be irradiated, using the incidence direction of the γ-rays that the second detector detects and information on detection positions of the γ-rays that the first detectors detect at substantially the same time period with the time point when the second detector detects the incidence direction of the γ-rays.
摘要翻译：要解决的问题：提供能够提高存在位置和三维正电子衰变核的范围的估计精度的正电子发射核位置检测装置。解决方案：正电子发射核位置检测装置包括：一对第一检测器其具有布置成横跨待粒子束照射的物体的一对平面，并且检测平面中的γ射线; 第二检测器，其相对于被照射物体沿与第一检测器不同的方向排列，并检测γ射线的入射方向; 以及估计装置，使用第二检测器检测器检测到的γ射线的入射方向和关于γ射线检测位置的信息来估计第二检测器在被照射物体中检测到的γ射线的发射位置第一检测器在第二检测器检测到γ射线的入射方向的时间点处于基本相同的时间段处检测。

10. 发明专利

JP2008173297A Charged particle beam irradiation device 有权
标题翻译：充电颗粒光束辐射装置
公开(公告)号：JP2008173297A
公开(公告)日：2008-07-31
申请号：JP2007009524
申请日：2007-01-18
申请人： National Cancer Center-Japan , Sumitomo Heavy Ind Ltd , 住友重機械工業株式会社 , 国立がんセンター総長
发明人： NISHIO TEIJI , OGINO TAKASHI , NOMURA KAZUHIRO , TACHIKAWA TOSHIKI
IPC分类号： A61N5/10 , A61B6/00 , A61N5/01 , G01T1/161 , G21K5/00 , G21K5/04
摘要： PROBLEM TO BE SOLVED: To provide a charged particle beam irradiation device permitting confirmation of an irradiation position in a desired region. SOLUTION: The charged particle beam irradiation device has an irradiation chamber 103 with a charged particle beam irradiation part 1 which is rotatable around an object 51 to be irradiated. A detection part 30 for detecting annihilation gamma rays generated in the object 51 to be irradiated is movable in the direction in which the axis X of rotation of the charged particle beam irradiation part 1. Accordingly, by moving the detection part 30 in the direction of the axis X, the detection part 30 can be prevented from preventing rotation of the charged particle beam irradiation part 1. Further, the detection part 30 will not be an obstacle in carrying the object to be irradiated into/out of the irradiation chamber 103, and the position of the desired region can be confirmed. Since the detection part 30 can be moved in the direction of the axis X according to the size of the object to be irradiated, the range of detection by the detection part 30 can be expanded. COPYRIGHT: (C)2008,JPO&INPIT
摘要翻译：要解决的问题：提供允许在期望区域中确认照射位置的带电粒子束照射装置。解决方案：带电粒子束照射装置具有照射室103，其具有能够围绕物体51旋转以照射的带电粒子束照射部分1。用于检测在被照射物体51中产生的湮灭伽马射线的检测部30能够沿着带电粒子束照射部1的旋转轴线X的方向移动。因此，通过使检测部30沿着可以防止轴线X，检测部件30阻止带电粒子束照射部分1的旋转。此外，检测部件30将不会妨碍将被照射入/离开照射室103的物体，并且可以确认所需区域的位置。由于检测部30能够根据被照射物的尺寸沿轴线X的方向移动，所以能够扩大检测部30的检测范围。版权所有（C）2008，JPO＆INPIT

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