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1. 发明授权

US06818006B2 Temporary intraluminal filter guidewire 失效
标题翻译：临时管腔内过滤器导丝
公开(公告)号：US06818006B2
公开(公告)日：2004-11-16
申请号：US09918441
申请日：2001-07-27
申请人： Nareak Douk , Nasser Rafiee , David S. Brin , Peter G. Strickler , Jerry Brightbill , James F. Crittenden
发明人： Nareak Douk , Nasser Rafiee , David S. Brin , Peter G. Strickler , Jerry Brightbill , James F. Crittenden
IPC分类号： A61M2900
CPC分类号： A61B17/12022 , A61B17/1204 , A61B17/12109 , A61B17/12172 , A61B2017/1205 , A61B2017/12095 , A61B2017/22038 , A61B2017/22045 , A61F2/013 , A61F2002/011 , A61F2002/018 , A61F2230/0006 , A61F2230/0067 , A61F2230/0071
摘要： The present invention is a temporary intraluminal filter guidewire for use during interventional procedures, such as angioplasty or stent deployment. A braided filter is mounted near the distal end of a steerable guidewire, which guides a therapeutic catheter. An actuator rod slides over the guidewire and is removably connected to the filter. The rod controls relative displacement of the filter ends, causing transformation of the filter between a deployed configuration and a collapsed configuration. In several embodiments, the guidewire distal to the filter has a fixed tip length. Other embodiments of the invention include a mechanism for damping longitudinal movement between the distal and proximal ends of the filter.
摘要翻译：本发明是在介入手术期间使用的临时管腔内过滤器导丝，例如血管成形术或支架展开。编织过滤器安装在引导治疗导管的可导向导丝的远端附近。致动器杆在导丝上滑动并且可移除地连接到过滤器。杆控制过滤器端部的相对位移，导致过滤器在部署配置和折叠配置之间的转换。在几个实施例中，远离过滤器的导丝具有固定的尖端长度。本发明的其它实施例包括用于阻止过滤器的远端和近端之间的纵向移动的机构。

2. 发明授权

US07066946B2 Temporary intraluminal filter guidewire 失效
公开(公告)号：US07066946B2
公开(公告)日：2006-06-27
申请号：US10797558
申请日：2004-03-10
申请人： Nareak Douk , Nasser Rafiee , David S. Brin , Peter G. Strickler , James F. Crittenden
发明人： Nareak Douk , Nasser Rafiee , David S. Brin , Peter G. Strickler , James F. Crittenden
IPC分类号： A61M29/00
CPC分类号： A61B17/12022 , A61B17/1204 , A61B17/12109 , A61B17/12172 , A61B2017/1205 , A61B2017/12095 , A61B2017/22038 , A61B2017/22045 , A61F2/013 , A61F2002/011 , A61F2002/018 , A61F2230/0006 , A61F2230/0067 , A61F2230/0071
摘要： The present invention is a temporary intraluminal filter guidewire for use during interventional procedures, such as angioplasty or stent deployment. A braided filter is mounted near the distal end of a steerable guidewire, which guides a therapeutic catheter. An actuator rod slides over the guidewire and is removably connected to the filter. The rod controls relative displacement of the filter ends, causing transformation of the filter between a deployed configuration and a collapsed configuration. In several embodiments, the guidewire distal to the filter has a fixed tip length. Other embodiments of the invention include a mechanism for damping longitudinal movement between the distal and proximal ends of the filter.

3. 发明授权

US06866677B2 Temporary intraluminal filter guidewire and methods of use 失效
标题翻译：临时管腔内过滤器导丝及使用方法
公开(公告)号：US06866677B2
公开(公告)日：2005-03-15
申请号：US09824832
申请日：2001-04-03
申请人： Nareak Douk , Nasser Rafiee , David S. Brin , Peter G. Strickler
发明人： Nareak Douk , Nasser Rafiee , David S. Brin , Peter G. Strickler
IPC分类号： A61B17/00 , A61B17/22 , A61F2/01 , A61F2/82 , A61M25/00 , A61M29/00
CPC分类号： A61F2/013 , A61B2017/1205 , A61B2017/12095 , A61F2002/015 , A61F2002/018 , A61F2230/0006 , A61F2230/0069 , A61F2230/0071 , A61F2230/008
摘要： The present invention is a temporary intraluminal filter guidewire for use during interventional procedures, such as angioplasty or stent deployment. A braided filter is mounted near the distal end of a steerable guidewire, which guides a therapeutic catheter. An actuator rod slides over the guidewire and is removably connected to the filter. The rod controls relative displacement of the filter ends, causing transformation of the filter between a deployed configuration and a collapsed configuration. Wire having enhanced radiopacity is included in the filter to provide visualization under fluoroscopy.
摘要翻译：本发明是在介入手术期间使用的临时管腔内过滤器导丝，例如血管成形术或支架展开。编织过滤器安装在引导治疗导管的可导向导丝的远端附近。致动器杆在导丝上滑动并且可移除地连接到过滤器。杆控制过滤器端部的相对位移，导致过滤器在部署配置和折叠配置之间的转换。具有增强的射线不透性的线被包括在过滤器中以在荧光透视下提供可视化。

4. 发明授权

US07371249B2 Temporary intraluminal filter guidewire and methods of use 失效
标题翻译：临时管腔内过滤器导丝及使用方法
公开(公告)号：US07371249B2
公开(公告)日：2008-05-13
申请号：US11053368
申请日：2005-02-08
申请人： Nareak Douk , Nasser Rafiee , David S. Brin , Peter G. Strickler
发明人： Nareak Douk , Nasser Rafiee , David S. Brin , Peter G. Strickler
IPC分类号： A61M29/00
CPC分类号： A61F2/013 , A61B2017/1205 , A61B2017/12095 , A61F2002/015 , A61F2002/018 , A61F2230/0006 , A61F2230/0069 , A61F2230/0071 , A61F2230/008
摘要： The present invention is a temporary intraluminal filter guidewire for use during interventional procedures, such as angioplasty or stent deployment. A braided filter is mounted near the distal end of a steerable guidewire, which guides a therapeutic catheter. An actuator rod slides over the guidewire and is removably connected to the filter. The rod controls relative displacement of the filter ends, causing transformation of the filter between a deployed configuration and a collapsed configuration. Wire having enhanced radiopacity is included in the filter to provide visualization under fluoroscopy.
摘要翻译：本发明是在介入手术期间使用的临时管腔内过滤器导丝，例如血管成形术或支架展开。编织过滤器安装在引导治疗导管的可导向导丝的远端附近。致动器杆在导丝上滑动并且可移除地连接到过滤器。杆控制过滤器端部的相对位移，导致过滤器在部署配置和折叠配置之间的转换。具有增强的射线不透性的线被包括在过滤器中以在透视下提供可视化。

5. 发明授权

US06602271B2 Collapsible blood filter with optimal braid geometry 失效
公开(公告)号：US06602271B2
公开(公告)日：2003-08-05
申请号：US09735140
申请日：2000-12-12
申请人： Bruce Adams , Ahmed Malek , Jerry R. Brightbill , Nasser Rafiee , Nareak Douk , David S. Brin , Dennis L. Brooks , Robert D. Lashinski
发明人： Bruce Adams , Ahmed Malek , Jerry R. Brightbill , Nasser Rafiee , Nareak Douk , David S. Brin , Dennis L. Brooks , Robert D. Lashinski
IPC分类号： A61M2900
CPC分类号： A61F2/013 , A61F2002/015 , A61F2002/018 , A61F2230/0006 , A61F2230/0067 , A61F2230/008
摘要： The present invention is a collapsible blood filter for use during a vascular procedure, such as angioplasty or stent deployment. A filter made of braided filaments is located on the distal end of a delivery member, and the filter is deployed downstream of the vascular treatment site to capture emboli released during and immediately after the procedure. Optimal braid geometry of the filter ensures that captured emboli will be retained during collapse and removal of the filter following the procedure.

6. 发明授权

US06716231B1 Distal protection device 失效
标题翻译：远端保护装置
公开(公告)号：US06716231B1
公开(公告)日：2004-04-06
申请号：US09578244
申请日：2000-05-24
申请人： Nasser Rafiee , Jerry R. Brightbill , David S. Brin , Timothy P. Collins , Steven R. Dapolito , Barbara S. DeVaux , Nareak Douk , Albert H. Dunfee , Heng Mao , Michael S. Noone , Dennis L. Brooks , Robert D. Lashinski
发明人： Nasser Rafiee , Jerry R. Brightbill , David S. Brin , Timothy P. Collins , Steven R. Dapolito , Barbara S. DeVaux , Nareak Douk , Albert H. Dunfee , Heng Mao , Michael S. Noone , Dennis L. Brooks , Robert D. Lashinski
IPC分类号： A61M2900
CPC分类号： A61F2/013 , A61F2/01 , A61F2002/018 , A61F2230/0006 , A61F2230/0067 , A61F2230/008
摘要： The present invention is a distal protection device for use during a vascular treatment, such as angioplasty or atherectomy. A filter assembly located on the distal end of a delivery member is deployed distally of the vascular region to be treated to capture emboli released during and immediately after the procedure. The filter is then retracted to retain any captured emboli and then removed from the patient.
摘要翻译：本发明是一种用于血管成形术或粥样斑块切除术的血管治疗期间的远端保护装置。位于递送构件的远端上的过滤器组件被展开在待治疗的血管区域的远端以捕获在手术期间和之后立即释放的栓塞。然后将过滤器缩回以保留任何捕获的栓塞，然后从患者中取出。

7. 发明申请

US20120179054A1 PERIVASCULAR LEAK REPAIR SYSTEM 有权
标题翻译：全面泄漏修复系统
公开(公告)号：US20120179054A1
公开(公告)日：2012-07-12
申请号：US13312635
申请日：2011-12-06
申请人： Jeffrey W. Allen , David S. Brin , Chris M. Coppin
发明人： Jeffrey W. Allen , David S. Brin , Chris M. Coppin
IPC分类号： A61B5/02 , A61M25/00 , A61B17/03
CPC分类号： A61B17/00491 , A61B2017/00243 , A61B2017/00783 , A61F2/2409
摘要： The perivascular leak repair system, and method of using the same, of the present invention provides a sealant reservoir with a repair catheter operably attached; a flow control device disposed between the sealant reservoir and the repair catheter, and the flow control device responsive to a flow control signal; a heart phase detector generating a diastole phase signal; an injection switch generating a injection signal; and a flow controller responsive to the diastole phase signal and the injection signal, and generating the flow control signal. A method of sealing a perivascular leak comprises identifying the perivascular leak; inserting a repair catheter to the perivascular leak; injecting sealant at the perivascular leak; and removing the repair catheter. The sealant can be injected when the heart is in diastole to sweep the sealant into the perivascular leak.
摘要翻译：本发明的血管周围泄漏修复系统及其使用方法提供了具有可操作地附接的修复导管的密封剂储存器; 设置在密封剂储存器和修复导管之间的流量控制装置，以及响应于流量控制信号的流量控制装置; 产生舒张期相位信号的心脏相位检测器; 产生喷射信号的喷射开关; 以及响应于舒张期相位信号和注射信号的流量控制器，并且产生流量控制信号。密封血管周围渗漏的方法包括鉴定血管周围的泄漏; 将维修导管插入血管周围的泄漏; 在血管周围的泄漏处注射密封剂; 并移除修复导管。当心脏舒张时，可以注射密封剂，以将密封剂扫入血管周围的泄漏。

8. 发明授权

US5388590A Catheter exchange device 失效
标题翻译：导管交换装置
公开(公告)号：US5388590A
公开(公告)日：1995-02-14
申请号：US98185
申请日：1993-07-28
申请人： John B. Horrigan , Peter A. Lunn , David S. Brin
发明人： John B. Horrigan , Peter A. Lunn , David S. Brin
IPC分类号： A61M25/01 , A61B5/00
CPC分类号： A61M25/0169
摘要： The invention includes an exchange system, a guidewire anchoring means and a method of use for catheters exchangeable over a guidewire (55). The guidewire anchoring means restricts movement between the guidewire (55) and the anchoring means. The anchoring means comprises a shaft (35) with a longitudinal lumen (80) therethrough, the lumen (80) being in fluid communication with a balloon (25 or 30) disposed on the distal end of the shaft (35). A tubular split housing (5 or 10) surrounds the distal end of the shaft (35) and adheres to the balloon (25 or 30), the balloon (25 or 30) being sized to expand to a larger size than the inside diameter of the split housing (5 or 10). The inside diameter of the split housing (5 or 10) is sized to slidably receive a catheter, while the outside diameter of the split housing (5 or 10) is sized to slidably fit within a guide catheter (50 ).
摘要翻译：本发明包括交换系统，导丝锚固装置和用于可在导丝（55）上交换的导管的方法。导丝锚固装置限制导丝（55）和锚定装置之间的移动。锚定装置包括具有穿过其中的纵向腔（80）的轴（35），所述腔（80）与设置在轴（35）的远端上的球囊（25或30）流体连通。管状分离式外壳（5或10）围绕轴（35）的远端并且粘附到球囊（25或30）上，球囊（25或30）的尺寸设定成比内径分离式外壳（5或10）。分割式外壳（5或10）的内径的尺寸设计成可滑动地容纳导管，而分离式外壳（5或10）的外径的尺寸可滑动地配合在导向导管（50）内。

9. 发明申请

US20090312743A1 Perivascular Leak Repair System 有权
标题翻译：血管周围渗漏修复系统
公开(公告)号：US20090312743A1
公开(公告)日：2009-12-17
申请号：US12502294
申请日：2009-07-14
申请人： Jeffrey A. Allen , David S. Brin , Chris M. Coppin
发明人： Jeffrey A. Allen , David S. Brin , Chris M. Coppin
IPC分类号： A61M31/00 , A61B17/08
CPC分类号： A61B17/00491 , A61B2017/00243 , A61B2017/00783 , A61F2/2409
摘要： The perivascular leak repair system, and method of using the same, of the present invention provides a sealant reservoir 102 with a repair catheter 104 operably attached; a flow control device 106 disposed between the sealant reservoir 102 and the repair catheter 104, and the flow control device 106 responsive to a flow control signal 108; a heart phase detector 114 generating a diastole phase signal 112; an injection switch 122 generating a injection signal 120; and a flow controller 110 responsive to the diastole phase signal 112 and the injection signal 120, and generating the flow control signal 108. A method of sealing a perivascular leak comprises identifying the perivascular leak 140; inserting a repair catheter to the perivascular leak 142; injecting sealant at the perivascular leak 144; and removing the repair catheter 146. The sealant can be injected when the heart is in diastole to sweep the sealant into the perivascular leak.
摘要翻译：本发明的血管周围泄漏修复系统及其使用方法提供了具有可操作地附接的修复导管104的密封剂储存器102; 布置在密封剂储存器102和修复导管104之间的流量控制装置106以及响应于流量控制信号108的流量控制装置106; 产生舒张期相位信号112的心脏相位检测器114; 产生喷射信号120的喷射开关122; 以及响应于舒张期相位信号112和注射信号120的流量控制器110，以及产生流量控制信号108.密封血管周围的泄漏的方法包括识别血管周围的泄漏140; 将维修导管插入血管周围的泄漏142; 在血管周围泄漏144处注射密封剂; 并且移除修复导管146.当心脏舒适时可以注射密封剂以将密封剂扫过血管周围的泄漏。

10. 发明授权

US06989027B2 Percutaneously delivered temporary valve assembly 有权
标题翻译：经皮递送临时阀组件
公开(公告)号：US06989027B2
公开(公告)日：2006-01-24
申请号：US10835153
申请日：2004-04-29
申请人： Jeffrey W. Allen , David S. Brin , Chris M. Coppin
发明人： Jeffrey W. Allen , David S. Brin , Chris M. Coppin
IPC分类号： A61F2/06
CPC分类号： A61F2/2427 , A61F2/2412 , A61F2250/0059
摘要： The percutaneously delivered temporary valve assembly of the present invention, and method of using the same, provides an elongate element and a temporary valve disposed on the elongate element. The temporary valve can comprise struts and a membrane attached to the struts. The elongate element can include at least one lumen. The percutaneously delivered temporary valve assembly can be used to replace an aortic valve by locating a temporary valve in a patient's ascending aorta; deploying the temporary valve; removing the native aortic valve past the temporary valve; implanting the prosthetic aortic valve past the temporary valve; collapsing the temporary valve; and removing the temporary valve from the patient. The temporary valve can be sized to the patient and can be left in place while the prosthetic aortic valve heals in.
摘要翻译：本发明的经皮递送的临时阀组件及其使用方法提供了细长元件和设置在细长元件上的临时阀。临时阀可以包括支柱和附接到支柱的膜。细长元件可以包括至少一个内腔。经皮递送的临时阀组件可用于通过将临时瓣膜置于患者升主动脉中来替代主动脉瓣膜; 部署临时阀门; 去除原发性主动脉瓣通过临时阀门; 将假体主动脉瓣植入临时阀门; 塌缩临时阀门; 并从患者身上移除临时阀。临时阀门可以根据患者的尺寸设计，并且可以在假体主动脉瓣愈合时留在原处。

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