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1. 发明授权

US5707817A Carbohydrate-based vaccine and diagnostic reagent for trichinosis 失效
标题翻译：基于碳水化合物的疫苗和旋毛虫病诊断试剂
公开(公告)号：US5707817A
公开(公告)日：1998-01-13
申请号：US415365
申请日：1995-03-31
申请人： Nancy Wisnewski , Robert B. Grieve , Donald L. Wassom , Michael R. McNeil
发明人： Nancy Wisnewski , Robert B. Grieve , Donald L. Wassom , Michael R. McNeil
IPC分类号： A61K39/00 , G01N33/53 , G01N33/569 , A61K31/70
CPC分类号： G01N33/569 , A61K39/0003 , G01N33/5308
摘要： The present invention relates to Trichinella diagnostic reagents that include a .beta.-tyvelose-containing composition and use of such reagents to detect Trichinella, and particularly Trichinella spiralis infections. The present invention also includes diagnostic kits based on such reagents and therapeutic agents based on the the knowledge that .beta.-tyvelose is produced by Trichinella spiralis parasites.
摘要翻译：本发明涉及旋毛虫诊断试剂，其包括含有β-依维螺素的组合物和这种试剂用于检测旋毛虫，特别是旋毛虫感染。本发明还包括基于这样的试剂和治疗剂的诊断试剂盒，基于β-螺旋体由旋毛虫寄生虫产生的知识。

2. 发明授权

US5686256A Carbohydrate-based vaccine and diagnostic reagent for trichinosis 失效
标题翻译：基于碳水化合物的疫苗和旋毛虫病诊断试剂
公开(公告)号：US5686256A
公开(公告)日：1997-11-11
申请号：US459303
申请日：1995-06-02
申请人： Nancy Wisnewski , Robert B. Grieve , Donald L. Wassom , Michael R. McNeil
发明人： Nancy Wisnewski , Robert B. Grieve , Donald L. Wassom , Michael R. McNeil
IPC分类号： A61K39/00 , G01N33/53 , G01N33/569 , A61K31/70
CPC分类号： G01N33/569 , A61K39/0003 , G01N33/5308
摘要： The present invention relates to Trichinella diagnostic reagents that include at least one tyvelose-containing oligosaccharide, or functional equivalent thereof, and use of such reagents to detect Trichinella, and particularly Trichinella spiralis infections. The present invention also includes diagnostic kits based on such reagents and anti-Trichinella spiralis drugs based on the knowledge that tyvelose is produced by Trichinella spiralis parasites.
摘要翻译：本发明涉及包含至少一种含有叶绿素的寡糖或其功能等同物的旋毛虫诊断试剂，以及使用这些试剂来检测旋毛虫，特别是旋毛虫感染。本发明还包括基于这样的试剂和抗旋毛虫药物的诊断试剂盒，其基于螺旋体由旋毛虫寄生虫产生的知识。

3. 发明授权

US5541075A Carbohydrate-based vaccine and diagnostic reagent for trichinosis 失效
标题翻译：基于碳水化合物的疫苗和旋毛虫病诊断试剂
公开(公告)号：US5541075A
公开(公告)日：1996-07-30
申请号：US14449
申请日：1993-02-05
申请人： Nancy Wisnewski , Robert B. Grieve , Donald L. Wassom , Michael R. McNeil
发明人： Nancy Wisnewski , Robert B. Grieve , Donald L. Wassom , Michael R. McNeil
IPC分类号： A61K39/00 , G01N33/53 , G01N33/569 , A61K31/70
CPC分类号： G01N33/569 , A61K39/0003 , G01N33/5308
摘要： The present invention relates to Trichinella vaccines that include at least one tyvelose-containing oligosaccharide or functional equivalent thereof, to Trichinella vaccines that include at least one fucose-containing oligosaccharide or functional equivalent thereof, and to the use of such vaccines to protect animals from Trichinella infections, and particularly from trichinosis caused by Trichinella spiralis infection. Such vaccines can also be used to produce antibodies that are capable of protecting an animal from Trichinella infections and of diagnosing such infections. The present invention also relates to Trichinella diagnostic reagents that include at least one tyvelose-containing oligosaccharide, or functional equivalent thereof, and use of such reagents to detect Trichinella, and particularly Trichinella spiralis infections. The present invention also includes diagnostic kits based on such reagents and anti-Trichinella-spiralis drugs based on the knowledge that tyvelose is produced by Trichinella spiralis parasites.
摘要翻译：本发明涉及包含至少一种含有叶绿素的寡糖或其功能等同物的旋毛虫疫苗，其包含至少一种含岩藻糖的寡糖或其功能等同物的旋毛属疫苗，以及使用这种疫苗来保护动物免受旋毛虫感染，特别是由旋毛虫感染引起的旋毛虫感染。此类疫苗也可用于产生能够保护动物免受旋毛虫感染和诊断此类感染的抗体。本发明还涉及包含至少一种含有叶酸的寡糖或其功能等同物的旋毛虫诊断试剂，以及使用这些试剂来检测旋毛虫，特别是旋毛虫感染。本发明还包括基于这样的试剂和抗旋毛虫螺旋体药物的诊断试剂盒，其基于由旋毛虫螺旋体寄生虫产生的叶绿素的知识。

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