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1. 发明申请

WO02058488A3 COMPOSITION CONTAINING CREATINE AND PHOSPHORUS 审中-公开
标题翻译：含有肌酸和磷的组合物
公开(公告)号：WO02058488A3
公开(公告)日：2002-11-21
申请号：PCT/NL0200062
申请日：2002-01-28
申请人： NUTRICIA NV , STOUT JEFFREY RAY , SMEETS RUDOLF LEONARDUS LODEWI , VERLAAN GEORGE , STEENGE GEESIEN ROELIEN
发明人： STOUT JEFFREY RAY , SMEETS RUDOLF LEONARDUS LODEWI , VERLAAN GEORGE , STEENGE GEESIEN ROELIEN
IPC分类号： A23L1/304 , A23L1/30 , A61K31/195
CPC分类号： A23L33/16 , A23V2002/00 , A23V2250/306 , A23V2250/1618
摘要： The invention discloses a composition comprising (a) soluble creatine, (b) a phosphorus supplement, wherein the phosphorus supplement provides at least 75 % of the recommended daily dose of phosphorus value per serving, and (c) a blood buffer, which is preferably citrate and/or (bi)carbonate. The composition is used in a method for increasing the energy capacity within tissue cells.
摘要翻译：本发明公开了一种组合物，其包含（a）可溶性肌酸，（b）磷补充剂，其中所述磷补充剂提供每份推荐的每日磷剂值的至少75％，和（c）血液缓冲剂，其优选柠檬酸盐和/或（二）碳酸盐。该组合物用于增加组织细胞内能量容量的方法中。

2. 发明申请

WO02058792A8 REHYDRATION COMPOSITION 审中-公开
标题翻译：再结晶组合物
公开(公告)号：WO02058792A8
公开(公告)日：2003-11-06
申请号：PCT/NL0200063
申请日：2002-01-28
申请人： NUTRICIA NV , HAGEMAN ROBERT JOHAN JOSEPH , VERLAAN GEORGE , SMEETS RUDOLF LEONARDUS LODEWI
发明人： HAGEMAN ROBERT JOHAN JOSEPH , VERLAAN GEORGE , SMEETS RUDOLF LEONARDUS LODEWI
IPC分类号： A23L1/304 , A23L2/38 , A61K45/06 , A61P1/12 , A61K31/35 , A61K31/70
CPC分类号： A23L2/38 , A23L33/16 , A23V2002/00 , A61K45/06 , A23V2250/5114 , A23V2250/0644 , A23V2250/0632 , A23V2250/061 , A23V2250/606 , A23V2250/1614 , A23V2250/16
摘要： The invention relates to a fluid that can be used for preventing or treating hypohydration and the secondary consequences thereof. The fluid comprises one or more carbohydrates and minerals and is further characterized by a low osmolarity. The invention further relates to the use of such a fluid for medical, dietetic and other applications.
摘要翻译：本发明涉及可用于预防或治疗缺氧的流体及其二次后果。流体包含一种或多种碳水化合物和矿物质，其进一步特征在于低渗透压。本发明还涉及这种流体用于医疗，饮食和其它应用的用途。

3. 发明申请

WO2011078677A3 LOW-CALORIC HIGH-PROTEIN NUTRITIONAL COMPOSITION FOR THE STIMULATION OF MUSCLE PROTEIN SYNTHESIS 审中-公开
标题翻译：用于刺激肌肉蛋白合成的低钙高蛋白营养组合物
公开(公告)号：WO2011078677A3
公开(公告)日：2011-09-09
申请号：PCT/NL2010050887
申请日：2010-12-23
申请人： NUTRICIA NV , LUIKING YVETTE CHARLOTTE , VERLAAN GEORGE , JOURDAN MARION
发明人： LUIKING YVETTE CHARLOTTE , VERLAAN GEORGE , JOURDAN MARION
IPC分类号： A61K35/20
CPC分类号： A23L1/296 , A23L33/15 , A23L33/16 , A23L33/175 , A23L33/19 , A23L33/21 , A23L33/40 , A61K31/70 , A61K35/74 , A61K38/1709
摘要： The present invention relates to the use of a low-caloric high-protein nutritional composition for use in the prevention or treatment of a disease or condition in a mammal, which involves muscle decline, as well as to specific low-caloric high-protein nutritional compositions for stimulating muscle protein synthesis in a mammal. In particular, the invention relates to the use of a nutritional composition comprising per 100 kcal : (i) at least about 12 g of proteinaceous matter which comprises at least about 80 weight% of whey protein, relative to the total proteinaceous matter, and which comprises at least about 11 weight% of leucine, relative to the total proteinaceous matter, of which at least about 20 weight% is in a free form, relative to the total leucine, (ii) a source of fat and a source of digestible carbohydrates, for the prevention or treatment of a disease or condition which involves muscle decline in a mammal, especially an elderly mammal, wherein the nutritional composition is administered as 1 to 2 servings daily, each serving comprising between 80 and 200 kcal.
摘要翻译：本发明涉及低热量高蛋白营养组合物用于预防或治疗哺乳动物的疾病或病症，其涉及肌肉下降，以及特定的低热量高蛋白营养用于刺激哺乳动物肌肉蛋白质合成的组合物。特别地，本发明涉及包含每100千卡的营养组合物的用途：（i）至少约12克相对于总蛋白质物质至少约80重量％的乳清蛋白质的蛋白质物质，以及哪些相对于总蛋白质物质，其至少约11重量％的亮氨酸相对于总亮氨酸为至少约20重量％，其中至少约20重量％为游离形式，（ii）脂肪源和可消化碳水化合物源用于预防或治疗哺乳动物，特别是老年哺乳动物中涉及肌肉下降的疾病或病症，其中营养组合物每天以1-2份服用，每份服用包含80至200千卡。

4. 发明申请

WO2006112717A2 NUTRITIONAL SUPPLEMENT FOR A CATEGORY OF HIV PATIENTS 审中-公开
标题翻译：针对艾滋病毒患者的营养补充
公开(公告)号：WO2006112717A2
公开(公告)日：2006-10-26
申请号：PCT/NL2006050092
申请日：2006-04-19
申请人： NUTRICIA NV , GARSSEN JOHAN , VAN TOL ERIC ALEXANDER FRANCIS , SIJBEN JOHANNES WILHELMUS CHRI , VERLAAN GEORGE
发明人： GARSSEN JOHAN , VAN TOL ERIC ALEXANDER FRANCIS , SIJBEN JOHANNES WILHELMUS CHRI , VERLAAN GEORGE
IPC分类号： A23L33/00
CPC分类号： A61K31/70
摘要： The present invention relates to a nutritional product for HIV patients that are not on Highly Active Antiretroviral Therapy. More specifically the invention relates to a nutritional composition comprising oligosaccharides. This invention also relates to the manufacture of a nutritional supplement for use in HIV patients.
摘要翻译：本发明涉及不是高活性抗逆转录病毒疗法的HIV患者的营养产品。更具体地，本发明涉及包含寡糖的营养组合物。本发明还涉及用于HIV患者的营养补充剂的制造。

5. 发明申请

WO2004000042A2 METHOD AND COMPOSITION FOR TREATING OR PREVENTING CATABOLISM OR STIMULATING ANABOLISM IN A MAMMAL UNDERGOING METABOLIC STRESS 审中-公开
标题翻译：用于治疗或预防代谢性应激的哺乳动物或刺激性抗体的方法和组合物
公开(公告)号：WO2004000042A2
公开(公告)日：2003-12-31
申请号：PCT/NL0300449
申请日：2003-06-19
申请人： NUTRICIA NV , HAGEMAN ROBERT JOHAN JOSEPH , VERLAAN GEORGE
发明人： HAGEMAN ROBERT JOHAN JOSEPH , VERLAAN GEORGE
IPC分类号： A23L1/29 , A23L1/30 , A23L1/302 , A23L1/304 , A23L1/305 , A61K31/133 , A61K31/14 , A61K31/195 , A61K31/198 , A61K31/205 , A61K31/525 , A61K31/685 , A61K31/7004 , A61K31/7072 , A61K31/7076 , A61K38/00 , A61K38/16 , A61K45/06 , A61P1/00 , A61P3/00 , A61P3/06 , A61P3/10 , A61P9/00 , A61P9/12 , A61P11/00 , A61P15/00 , A61P17/02 , A61P25/00 , A61P25/06 , A61P27/16 , A61P29/00 , A61P31/04 , A61P35/00 , A61P37/08
CPC分类号： A61K45/06 , A23L33/115 , A23L33/15 , A23L33/16 , A23L33/175 , A23L33/19 , A23L33/30 , A23L33/40 , A23V2002/00 , A61K31/195 , A61K38/16 , A61K2300/00 , A23V2250/0642 , A23V2200/308 , A23V2200/322 , A23V2200/324 , A23V2200/326 , A23V2200/328
摘要： The invention is concerned with a method and a composition for treating or preventing catabolism or of stimulating anabolism in a mammal undergoing metabolic stress. The method comprises administering to the mammal a composition containing methyl donors selected from the group consisting of L-serine, methionine, choline, phosphatidyl choline, betaine, dimethylglycine, sarcosine, methylated folates, S-adenosyl methionine, thymidine triphosphate, adenosine triphosphate and optionally methyl acceptors selected from the group consisting of L-glycine, ethanolamine, phosphatidyl ethanolamine, folate, ribose, wherein the total molar amount of methyl donors delivered by the method exceeds the total molar amount of methyl acceptors delivered by the method by at least 0.18 mmol per kg of body weight per day.
摘要翻译：本发明涉及用于治疗或预防经历代谢应激的哺乳动物中的分解代谢或刺激合成代谢的方法和组合物。该方法包括向哺乳动物施用含有选自L-丝氨酸，甲硫氨酸，胆碱，磷脂酰胆碱，甜菜碱，二甲基甘氨酸，肌氨酸，甲基化叶酸，S-腺苷甲硫氨酸，胸苷三磷酸，三磷酸腺苷和任选地选自L-甘氨酸，乙醇胺，磷脂酰乙醇胺，叶酸，核糖的甲基受体，其中通过该方法递送的甲基供体的总摩尔量超过通过该方法递送至少0.18mmol的甲基受体的总摩尔量每公斤体重每天。

6. 发明申请

WO2006112716A3 NUTRITIONAL SUPPLEMENT FOR HIV PATIENTS 审中-公开
标题翻译：营养补充艾滋病毒患者
公开(公告)号：WO2006112716A3
公开(公告)日：2007-05-10
申请号：PCT/NL2006050091
申请日：2006-04-19
申请人： NUTRICIA NV , GARSSEN JOHAN , VAN TOL ERIC ALEXANDER FRANCIS , SIJBEN JOHANNES WILHELMUS CHRI , VERLAAN GEORGE
发明人： GARSSEN JOHAN , VAN TOL ERIC ALEXANDER FRANCIS , SIJBEN JOHANNES WILHELMUS CHRI , VERLAAN GEORGE
IPC分类号： A23L1/29 , A61K31/70 , A61P31/18
CPC分类号： A61K31/70 , A23L33/12 , A23L33/175 , A23L33/18 , A23L33/185 , A23L33/21 , A23L33/40 , A23V2002/00 , A23V2250/54242 , A23V2250/5424 , A23V2250/1882 , A23V2250/0616 , A23V2250/28 , A23V2250/5062 , A23V2250/0634 , A23V2250/606 , A23V2250/6406
摘要： The present invention relates to a nutritional product for HIV patients. More specifically the invention relates to a nutritional composition that provides carefully selected nutritional ingredients including oligosaccharides and cysteine and/or a source of cysteine specifically supporting HIV patients with nutritionally related symptoms. This invention also relates to the manufacture of a nutritional supplement for use in HIV patients.
摘要翻译：本发明涉及HIV患者的营养产品。更具体地，本发明涉及营养组合物，其提供精心选择的营养成分，包括寡糖和半胱氨酸和/或特异性支持具有营养相关症状的HIV患者的半胱氨酸来源。本发明还涉及用于HIV患者的营养补充剂的制造。

7. 发明专利

AU2013392167A1 Muscle preservation in overweight or obese adult during weight loss program 未知
公开(公告)号：AU2013392167A1
公开(公告)日：2016-02-04
申请号：AU2013392167
申请日：2013-06-10
申请人： NUTRICIA NV
发明人： WEIJS PETER JOHAN MARIE , DE VOGEL JOHAN , VERLAAN GEORGE , JOURDAN MARION
IPC分类号： A23L33/00 , A23L33/155 , A23L33/17
摘要： The invention pertains to the use of a composition comprising per serving between 50 - 300 kcal; between 10 g and 35g proteinaceous matter; and at least 2.5 microgram vitamin D, for the manufacture of a nutritional product for (a) the treatment or prevention of muscle mass decrease, (b) stimulation of muscle mass increase; or (d) stimulating muscle mass preservation, in obese or overweight adults of at least 40 years of age participating in a weight loss program. The inventors surprisingly found that nutritional supplementation with a low-caloric composition rich in protein, particularly whey protein and leucine, compared to an iso-caloric control supplement without protein, synergistically leads to preservation of muscle mass during a weight loss program involving a hypocaloric diet and a resistance exercise program in overweight/obese older adult.

8. 发明专利

PL2515920T3 Niskokaloryczna wysokobiałkowa kompozycja odżywcza stymulująca syntezę białek mięśni 未知
公开(公告)号：PL2515920T3
公开(公告)日：2015-04-30
申请号：PL10807402
申请日：2010-12-23
申请人： NUTRICIA NV
发明人： LUIKING YVETTE CHARLOTTE , VERLAAN GEORGE , JOURDAN MARION
IPC分类号： A61K35/20 , A23L33/00 , A23L33/15

9. 发明专利

CA2914811A1 MUSCLE PRESERVATION IN OVERWEIGHT OR OBESE ADULT DURING WEIGHT LOSS PROGRAM 未知
公开(公告)号：CA2914811A1
公开(公告)日：2014-12-18
申请号：CA2914811
申请日：2013-06-10
申请人： NUTRICIA NV
发明人： WEIJS PETER JOHAN MARIE , DE VOGEL JOHAN , VERLAAN GEORGE , JOURDAN MARION
IPC分类号： A23L33/00 , A23L33/155
摘要： The invention pertains to the use of a composition comprising per serving between 50 - 300 kcal; between 10 g and 35g proteinaceous matter; and at least 2.5 microgram vitamin D, for the manufacture of a nutritional product for (a) the treatment or prevention of muscle mass decrease, (b) stimulation of muscle mass increase; or (d) stimulating muscle mass preservation, in obese or overweight adults of at least 40 years of age participating in a weight loss program. The inventors surprisingly found that nutritional supplementation with a low-caloric composition rich in protein, particularly whey protein and leucine, compared to an iso-caloric control supplement without protein, synergistically leads to preservation of muscle mass during a weight loss program involving a hypocaloric diet and a resistance exercise program in overweight/obese older adult.

10. 发明专利

AT551911T 未知
公开(公告)号：AT551911T
公开(公告)日：2012-04-15
申请号：AT06076906
申请日：2002-01-28
申请人： NUTRICIA NV
发明人： HAGEMAN ROBERT JOHAN JOSEPH , VERLAAN GEORGE , SMEETS RUDOLF LEONARDUS LODEWIJK
IPC分类号： A23L1/304 , A23L2/38 , A61K45/06 , A61P1/12
摘要： The invention relates to a fluid that can be used for preventing or treating hypohydration and the secondary consequences thereof. The fluid comprises one or more carbohydrates and minerals and is further is characterized by a low osmolarity. The invention further relates to the use of such a fluid for medical, dietetic and other applications.

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