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1. 发明申请

WO2007134954A1 AN INJECTION DEVICE WITH MODE LOCKING MEANS 审中-公开
标题翻译：具有模式锁定装置的注射装置
公开(公告)号：WO2007134954A1
公开(公告)日：2007-11-29
申请号：PCT/EP2007/054294
申请日：2007-05-03
申请人： NOVO NORDISK A/S , MØLLER, Claus Schmidt , PEDERSEN, Bennie Peder Smiszek , KVOLSBJERG, Bo
发明人： MØLLER, Claus Schmidt , PEDERSEN, Bennie Peder Smiszek , KVOLSBJERG, Bo
IPC分类号： A61M5/315
CPC分类号： A61M5/31553 , A61M5/20 , A61M5/24 , A61M5/31536 , A61M5/3155 , A61M5/31558 , A61M5/31566 , A61M5/31571 , A61M5/3158 , A61M5/31583 , A61M5/31585 , A61M2005/2407 , A61M2005/2411 , A61M2005/3125
摘要： An injection device comprising a housing, a dose setting member being operable to set a desired dose, a piston rod adapted to cooperate with a piston to cause a set dose to be expelled, and mode locking means. The mode locking means is adapted to be in a first extreme position and in a second extreme position. When the mode locking means is in the first extreme position the piston rod is prevented from cooperating with the piston, and when the mode locking means is in the second extreme position the dose setting member is prevented from being operated to set a dose. The mode locking means is adapted to be in the first extreme position during dose setting and the second extreme position during injection of a set dose. It is ensured that the liquid drug is not inadvertently expelled during dose setting and that blood or other body fluids is not sucked into the injection device during injection. Furthermore, inadvertent changing of the set dose during injection is prevented. The mechanism can readily be applied to injection devices which are not provided with a scale drum.
摘要翻译：一种注射装置，包括壳体，可操作以设定期望剂量的剂量设定构件，适于与活塞配合以引起固定剂量排出的活塞杆以及模式锁定装置。模式锁定装置适于处于第一极限位置和第二极限位置。当模式锁定装置处于第一极限位置时，防止活塞杆与活塞配合，并且当模式锁定装置处于第二极限位置时，防止剂量设定构件被操作以设定剂量。模式锁定装置适于在剂量设定期间处于第一极限位置，并且在注射设定剂量期间处于第二极限位置。确保在剂量设定期间液体药物不会被无意地排出，并且在注射期间血液或其它体液不被吸入注射装置。此外，防止注射期间设定剂量的无意改变。该机构可以容易地应用于没有设置刻度鼓的注射装置。

2. 发明申请

WO2010142598A3 INJECTION DEVICE HAVING ELECTRONIC DOSIS MONITOR 审中-公开
公开(公告)号：WO2010142598A3
公开(公告)日：2010-12-16
申请号：PCT/EP2010/057777
申请日：2010-06-03
申请人： NOVO NORDISK A/S , JESPERSEN, Søren, Kragh , BUSCHARDT, Claus, Valentin , HANSEN, Kim, Ejholm , KVOLSBJERG, Bo , PEDERSEN, Bennie, Peder, Smiszek , GJØDESEN, Claus, Urup , NIELSEN, Preben, Mikael , WITT, Marianne, Lindgård , PANDURO, Rasmus , LARSEN, André
发明人： JESPERSEN, Søren, Kragh , BUSCHARDT, Claus, Valentin , HANSEN, Kim, Ejholm , KVOLSBJERG, Bo , PEDERSEN, Bennie, Peder, Smiszek , GJØDESEN, Claus, Urup , NIELSEN, Preben, Mikael , WITT, Marianne, Lindgård , PANDURO, Rasmus , LARSEN, André
IPC分类号： A61M5/20 , A61M5/315
摘要： Medical injection advice adapted for operating in a dose setting mode and in a dose administration mode, comprising a dosing actuator (124) reversibly actuatable from a first state for operating the device in the dose setting mode to a second state for operating the device in the dose administration mode, a switch (130, 132) adapted to sense positional information associated with the dosing actuator, and a controller coupled to the switch arrangement, wherein electronic mode representation is configured to enter dose setting mode after a time delay following detecting the dosing actuator has moved away from said second state or detecting the dosing actuator has moved into said first state.

3. 发明申请

WO2008037801A1 AN INJECTION DEVICE WITH ELECTRONIC DETECTING MEANS 审中-公开
标题翻译：具有电子检测装置的注射装置
公开(公告)号：WO2008037801A1
公开(公告)日：2008-04-03
申请号：PCT/EP2007/060331
申请日：2007-09-28
申请人： NOVO NORDISK A/S , MØLLER, Claus Schmidt , KVOLSBJERG, Bo
发明人： MØLLER, Claus Schmidt , KVOLSBJERG, Bo
IPC分类号： A61M5/20 , A61M5/315 , G01D5/24
CPC分类号： A61M5/20 , A61M5/31553 , A61M5/31556 , A61M5/3156 , A61M5/31563 , A61M5/3157 , A61M5/31583 , A61M2005/202 , A61M2005/3125 , A61M2205/581 , A61M2205/582 , A61M2205/583 , G01D5/2412
摘要： An injection device (1) for injecting a dose of drug, e.g. insulin for diabetes treatment, in which energy is stored in a spring member (9, 24) during dose setting. The stored energy is released and used for driving an injection mechanism during injection of a previously set dose. The injection device (1) further comprises means for electronically detecting the amount of a set dose and/or means for electronically detecting the amount of an injected dose. The electronic detecting means allows storage and/or logging of data relating to injections performed using the injection device (1).
摘要翻译：一种注射装置（1），用于注射一定剂量的药物，例如，用于糖尿病治疗的胰岛素，其中在剂量设定期间能量存储在弹簧构件（9,24）中。储存的能量被释放并用于在注射预先设定的剂量期间驱动注射机构。注射装置（1）还包括用于电子检测设定剂量的量的装置和/或用于电子检测注射剂量的装置。电子检测装置允许存储和/或记录与使用注射装置（1）执行的注射有关的数据。

4. 发明公开

EP3833415A1 NEEDLE UNIT WITH FLOATING NEEDLE HUB 无效
公开(公告)号：EP3833415A1
公开(公告)日：2021-06-16
申请号：EP19746428.2
申请日：2019-08-09
申请人： Novo Nordisk A/S
发明人： BENGTSSON, Henrik , GLENTING, Vera, Pinto , PRÆSTMARK, Kezia Ann Friis , KVOLSBJERG, Bo
IPC分类号： A61M5/32

5. 发明申请

WO2022175242A1 DRUG DELIVERY DEVICE FOR DELIVERING A PREDEFINED FIXED DOSE 审中-公开
公开(公告)号：WO2022175242A1
公开(公告)日：2022-08-25
申请号：PCT/EP2022/053627
申请日：2022-02-15
申请人： NOVO NORDISK A/S
发明人： KVOLSBJERG, Bo , VILLADSEN, Nicolai, Michael
IPC分类号： A61M5/20 , A61M5/32 , A61M5/315
摘要： 1. A drug delivery device for delivering a plurality of fixed doses of a medicament, wherein the drug delivery device comprises a needle magazine with a plurality of needle assemblies, a needle positioning mechanism, a drive mechanism for delivering a fixed dose of the plurality of fixed doses, in response to activation, an activation mechanism for activating the drive mechanism comprising a movable shield (110, 310), wherein the shield (110, 310) is adapted to activate the drive mechanism, in response moving the shield to the proximal position. The drug delivery device further comprises a drop lock mechanism comprising a non-blocking state and a blocking state.

6. 发明授权

EP2023982B1 AN INJECTION DEVICE WITH MODE LOCKING MEANS 有权
标题翻译：与锁模注射装置
公开(公告)号：EP2023982B1
公开(公告)日：2012-07-11
申请号：EP07728747.2
申请日：2007-05-03
申请人： Novo Nordisk A/S
发明人： MØLLER, Claus Schmidt , PEDERSEN, Bennie Peder Smiszek , KVOLSBJERG, Bo
IPC分类号： A61M5/315
CPC分类号： A61M5/31553 , A61M5/20 , A61M5/24 , A61M5/31536 , A61M5/3155 , A61M5/31558 , A61M5/31566 , A61M5/31571 , A61M5/3158 , A61M5/31583 , A61M5/31585 , A61M2005/2407 , A61M2005/2411 , A61M2005/3125
摘要： An injection device comprising a housing, a dose setting member being operable to set a desired dose, a piston rod adapted to cooperate with a piston to cause a set dose to be expelled, and mode locking means. The mode locking means is adapted to be in a first extreme position and in a second extreme position. When the mode locking means is in the first extreme position the piston rod is prevented from cooperating with the piston, and when the mode locking means is in the second extreme position the dose setting member is prevented from being operated to set a dose. The mode locking means is adapted to be in the first extreme position during dose setting and the second extreme position during injection of a set dose. It is ensured that the liquid drug is not inadvertently expelled during dose setting and that blood or other body fluids is not sucked into the injection device during injection. Furthermore, inadvertent changing of the set dose during injection is prevented. The mechanism can readily be applied to injection devices which are not provided with a scale drum.

7. 发明申请

WO2019197061A1 FLOW COMMUNICATION UNIT WITH UNCONNECTED AND CONNECTED CONFIGURATION 审中-公开
公开(公告)号：WO2019197061A1
公开(公告)日：2019-10-17
申请号：PCT/EP2019/050555
申请日：2019-01-10
申请人： NOVO NORDISK A/S
发明人： BENGTSSON, Henrik , JENSEN, Brian , KVOLSBJERG, Bo
IPC分类号： A61M5/00 , A61M5/24 , A61M5/34 , A61M5/31 , A61M5/28 , A61J1/06
摘要： A flow communication unit (240, 540, 640, 740, 840, 940, 1040, 1140, 1240) for establishing flow communication from a multi-use drug delivery device adapted for extended use, to a flow conducting device, wherein the drug delivery device comprises a reservoir comprising multiple doses of a liquid drug formulation, wherein the reservoir is adapted to pressurize the liquid drug formulation, wherein the flow conducting device (230) is adapted for conducting the drug to the subcutaneous tissue of a subject, wherein the flow communication unit is adapted for being in an unconnected and a connected configarion, whereby the flow communication unit (240, 540, 640, 740, 840, 940, 1040, 1140,1240) is adapted to enable the extended use of the multi-use drug delivery device.

8. 发明申请

WO2019063818A1 CARTRIDGE SYSTEM FOR A DRUG DELIVERY DEVICE 审中-公开
公开(公告)号：WO2019063818A1
公开(公告)日：2019-04-04
申请号：PCT/EP2018/076519
申请日：2018-09-28
申请人： NOVO NORDISK A/S
发明人： BENGTSSON, Henrik , NIELSEN, Lars, Korsbjerg , KVOLSBJERG, Bo
IPC分类号： A61M5/315 , A61M5/24
摘要： A cartridge system for use with a drug delivery device (100'), comprising: - a pre-filled cartridge comprising: a) a cartridge body (210) accommodating a drug, b) a piston (250) slidably disposed in the cartridge body (210) and configured for providing a proximal seal, the piston (250) comprising: b1) a piston first member (260) comprising a first material and forming a distal end, a proximal end and a sealing periphery in contact with the cartridge body (210), wherein the distal end is in contact with the drug and wherein the proximal end of the piston first member (260) includes a proximally facing opening, and b2) a piston second member (270) comprising a material of lower compressibility compared to the first material, the piston second member (270) comprising a sleeve-formed portion arranged in the proximally facing opening of the piston first member (260), wherein the piston second member (270) comprises a proximally facing opening forming a socket; and - a plug unit (280) coupleable or coupled into the socket of the piston second member (270), wherein the plug unit (280) comprises an electronic sensor unit (290) configured to determine the axial position of the piston (250) within the cartridge body (210) and wherein the plug unit (280) is at least partially received within the proximally facing opening of the piston first member (260).

9. 发明申请

WO2022175241A1 DRUG DELIVERY DEVICE FOR DELIVERING A PREDEFINED FIXED DOSE 审中-公开
公开(公告)号：WO2022175241A1
公开(公告)日：2022-08-25
申请号：PCT/EP2022/053624
申请日：2022-02-15
申请人： NOVO NORDISK A/S
发明人： KVOLSBJERG, Bo , VILLADSEN, Nicolai, Michael
IPC分类号： A61M5/20 , A61M5/32 , A61M5/315
摘要： A drug delivery device (100, 300), comprising a rotatable drum (210, 410) with a plurality of needle assemblies, a shield (110, 410) and a needle change mechanism (134, 233, 105.2, 231, 105.2, 214, 305.1, 317). The needle change mechanism is operationally coupled to the drum (210, 410) and the shield (110, 310). The needle change mechanism is having an active state adapted to induce rotation of the drum (210, 410), in response to a movement of the shield (110, 310), the needle change mechanism further comprises a passive state wherein no rotation is induced on the drum (210, 410). The needle change mechanism is, in response to the second movement of the shield (110, 310), adapted to change from the passive state to the active state after the hollow needle (224, 424) disconnects from the cartridge, whereby it is prevented that the drum (210, 410) rotates while the hollow needle (224, 424) is connected with the cartridge.

10. 发明申请

WO2021122221A1 INJECTION DEVICE FOR DELIVERING A LIQUID DRUG AND A METHOD OF ASSEMBLY 审中-公开
公开(公告)号：WO2021122221A1
公开(公告)日：2021-06-24
申请号：PCT/EP2020/085273
申请日：2020-12-09
申请人： NOVO NORDISK A/S
发明人： JENSEN, Nicolai, Michael , KVOLSBJERG, Bo
IPC分类号： A61M5/24 , A61M5/32 , A61M5/315 , A61M5/20 , A61M5/31 , A61M2005/2013 , A61M2005/2073 , A61M2005/3267 , A61M2207/00 , A61M5/3146 , A61M5/31515 , A61M5/31585 , A61M5/326
摘要： The invention relates to a pre-filled injection device with a non-removable cartridge wherein the drive mechanics comprises a threaded piston rod which is moved helically in a nut secured to a housing structure. During assembly of the injection device it is possible to rotate the nut member to thereby advance the piston rod into a position eliminating any air-gap otherwise occurring between the piston rod and the plunger inside the cartridge

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