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1. 发明申请

WO2007017053A1 SYRINGE DEVICE WITH A DOSE LIMITING MECHANISM AND AN ADDITIONAL SAFETY MECHANISM 审中-公开
标题翻译：具有剂量限制机制和附加安全机制的SYRINGE装置
公开(公告)号：WO2007017053A1
公开(公告)日：2007-02-15
申请号：PCT/EP2006/007006
申请日：2006-07-17
申请人： NOVO NORDISK A/S , EILAND, Jacob , ENGGAARD, Christian, Peter , MØLLER, Claus, Schmidt , MARKUSSEN, Tom, Hede
发明人： EILAND, Jacob , ENGGAARD, Christian, Peter , MØLLER, Claus, Schmidt , MARKUSSEN, Tom, Hede
IPC分类号： A61M5/315
CPC分类号： A61M5/31583 , A61M5/20 , A61M5/31541 , A61M5/31553 , A61M5/31558 , A61M5/31561 , A61M5/31573 , A61M5/31593
摘要： A syringe device for ejecting a dose of a medicament, the syringe device comprising: a dose limiting mechanism arranged to interact with a dose ejecting mechanism to prevent ejection of a dose exceeding a set dose, and a safety mechanism, which is arranged such with respect to the dose ejecting mechanism that, if the dose limiting mechanism fails, the safety mechanism prevents ejection of a dose exceeding the set dose.
摘要翻译：一种用于喷射剂量的药物的注射器装置，所述注射器装置包括：剂量限制机构，其布置成与剂量喷射机构相互作用以防止超过剂量的剂量的喷射;以及安全机构，对于剂量排出机构，如果剂量限制机构失效，则安全机制防止超过设定剂量的剂量的喷射。

2. 发明申请

WO2006045526A1 DIAL-DOWN MECHANISM FOR WIND-UP PEN 审中-公开
标题翻译：用于上升笔的拨号机构
公开(公告)号：WO2006045526A1
公开(公告)日：2006-05-04
申请号：PCT/EP2005/011285
申请日：2005-10-20
申请人： NOVO NORDISK A/S , MØLLER, Claus, Schmidt , ENGGAARD, Christian, Peter , RADMER, Bo , MARKUSSEN, Tom, Hede
发明人： MØLLER, Claus, Schmidt , ENGGAARD, Christian, Peter , RADMER, Bo , MARKUSSEN, Tom, Hede
IPC分类号： A61M5/315 , A61M5/145
CPC分类号： A61M5/14566 , A61M5/20 , A61M5/31535 , A61M5/3155 , A61M5/31553 , A61M5/31583 , A61M5/31586 , A61M5/31593 , A61M2005/202
摘要： The present invention relates to a dial-down mechanism for an injection device comprising a torsion spring for assisting injection of a dose of medicament from the injection device, the dial-down mechanism comprising dial-up cam arranged to receive and engage with a dial-up key, wherein the dial-up cam and the dial-up key are adapted to, upon rotation of a dose setting member in a first direction, cooperate to strain the torsion spring of the injection device, and a dial-down cam arranged to receive and engage with a dial-down key, wherein the dial-down cam and the dial-down key are adapted to, upon rotation of the dose setting member in a second direction, cooperate to release the torsion spring of the injection device, the second rotation direction being opposite to the first rotation direction.
摘要翻译：本发明涉及一种用于注射装置的减速机构，其包括用于辅助从注射装置喷射剂量的药物的扭转弹簧，所述减速机构包括拨号凸轮，所述拨盘凸轮布置成接收和接合拨号装置，其中所述拨号凸轮和所述拨号键适于在剂量设定构件沿第一方向旋转时协作以使所述注射装置的扭转弹簧变形，以及拨号凸轮，其布置成接收和接合拨号键，其中拨号凸轮和拨号键适于在剂量设定构件沿第二方向旋转时协作以释放注射装置的扭转弹簧，第二旋转方向与第一旋转方向相反。

3. 发明申请

WO2007017052A1 DOSE MECHANISM FOR AN INJECTION DEVICE FOR LIMITING A DOSE SETTING CORRESPONDING TO THE AMOUNT OF MEDICAMENT LEFT 审中-公开
标题翻译：用于限制相对于左侧药物量的剂量设定的注射装置的剂量机构
公开(公告)号：WO2007017052A1
公开(公告)日：2007-02-15
申请号：PCT/EP2006/007004
申请日：2006-07-17
申请人： NOVO NORDISK A/S , ENGGAARD, Christian, Peter , MØLLER, Claus, Schmidt , MARKUSSEN, Tom, Hede
发明人： ENGGAARD, Christian, Peter , MØLLER, Claus, Schmidt , MARKUSSEN, Tom, Hede
IPC分类号： A61M5/315
CPC分类号： A61M5/31551 , A61M5/20 , A61M5/31505 , A61M5/31526 , A61M5/31528 , A61M5/31541 , A61M5/31553 , A61M5/3156 , A61M5/31571 , A61M5/31583 , A61M5/31586 , A61M5/31593 , A61M2005/202 , A61M2005/3151
摘要： A mechanism for preventing setting of a dose, which exceeds the amount of a medicament in a reservoir in an injection device. The device comprises a threaded piston rod, a limiter and a driver. The three elements are arranged such that during dose setting, the limiter is moved towards an end-of-contend position, wherein dose setting is limited. The invention comprises an accumulative and a non-accumulative embodiment. The invention further relates to a mechanism for prevention ejection of a dose exceeding the set dose.
摘要翻译：用于防止剂量设定超过注射装置中储存器中的药物量的机构。该装置包括螺纹活塞杆，限制器和驱动器。三个元件被布置成使得在剂量设定期间，限制器被移动到竞争结束位置，其中剂量设定受到限制。本发明包括累积和不累积的实施例。本发明还涉及用于预防超过设定剂量的剂量的喷射的机构。

4. 发明申请

WO2006089767A1 DOSE SETTING MECHANISM FOR AN INJECTION DEVICE CAPABLE OF PRESETTING A MAXIMUM DOSE 审中-公开
标题翻译：用于预设最大剂量的注射装置的剂量设定机构
公开(公告)号：WO2006089767A1
公开(公告)日：2006-08-31
申请号：PCT/EP2006/001707
申请日：2006-02-24
申请人： NOVO NORDISK A/S , MØLLER, Claus, Schmidt
发明人： MØLLER, Claus, Schmidt
IPC分类号： A61M5/315
CPC分类号： A61M5/31543 , A61M5/31528 , A61M5/31535 , A61M5/31536 , A61M5/31541 , A61M5/31551 , A61M5/31553 , A61M5/3158 , A61M2005/3154 , A61M2202/0007 , A61M2205/58
摘要： A dose setting mechanism for an injection device having a rotatably operated dose setting member. Has a presetting member being operable to limit the maximum dose settable by the dose setting member. A first stopping member is operatively connected to the presetting member, and the position of the first stopping member indicates the preset maximum dose. The first stopping member is adapted to rotatably engage with a second stopping member when the preset maximum dose has been set, thereby preventing setting of a further dose. The first and/or the second stopping member is/are movable along with the dose setting member, the first and second stopping members thereby being moved into engagement when a dose is set. Thereby a dose can be preset and the preset dose can easily be repeatedly set while ensuring an accurate dosage. Helps persons being visually impaired or having poor dexterity in setting a correct and accurate dose. Further, an injection device with a dose setting mechanism, particularly for self-injection of e.g. insulin.
摘要翻译：一种用于具有可旋转操作的剂量设定构件的注射装置的剂量设定机构。具有预设构件可操作以限制由剂量设定构件可设定的最大剂量。第一止动构件可操作地连接到预置构件，并且第一止动构件的位置指示预设的最大剂量。当预设的最大剂量被设定时，第一止动件适于与第二止挡件可旋转地接合，从而防止设定另外的剂量。第一和/或第二止动件可随着剂量设定件一起移动，因此当设定剂量时，第一和第二止挡件就被移动到接合中。因此，可以预设剂量，并且可以容易地重复设置预设剂量，同时确保准确的剂量。帮助视力障碍者或具有较差灵巧性的人设定正确和准确的剂量。此外，具有剂量设定机构的注射装置，特别是用于自体注射的剂量设定机构。胰岛素。

5. 发明申请

WO2005070482A1 IMPULSE CHAMBER FOR JET DELIVERY DEVICE 审中-公开
标题翻译：喷射装置的冲击室
公开(公告)号：WO2005070482A1
公开(公告)日：2005-08-04
申请号：PCT/DK2005/000042
申请日：2005-01-24
申请人： NOVO NORDISK A/S , HANSEN, Torben, Strøm , MØLLER, Claus, Schmidt
发明人： HANSEN, Torben, Strøm , MØLLER, Claus, Schmidt
IPC分类号： A61M5/24
CPC分类号： A61M5/30 , A61M5/2425 , A61M5/482
摘要： The invention relates to an impulse chamber (1, 2, 3) which can be used for expelling an amount of a fluid compound at a high pressure. The impulse chamber comprises a variable-volume impulse chamber (11, 55) adapted for containing a volume of a flowable drug, an outlet nozzle (23, 61) in fluid communication with the impulse chamber and being adapted to be arranged against the skin of a subject, and a fluid inlet (33, 39, 51) in fluid communication with the impulse chamber. The impulse chamber is defined substantially by a deformable chamber portion (10, 50), such that deformation thereof reduces the volume of the cavity. In an exemplary embodiment the compressible chamber portion is in the form of an elastomeric tube, this providing a simple, yet reliable and cost-effective impulse chamber unit.
摘要翻译：本发明涉及一种可用于在高压下排出一定量的流体化合物的脉冲室（1,2,3）。脉冲室包括适于容纳可流动药物的体积的可变容积脉冲室（11,55），与脉冲室流体连通的出口喷嘴（23,61），并且适于被布置成抵抗皮肤主体和与冲击室流体连通的流体入口（33,39,51）。脉冲室基本上由可变形的室部分（10,50）限定，使得其变形减小了空腔的体积。在示例性实施例中，可压缩室部分是弹性体管的形式，这提供了简单但可靠且具有成本效益的冲击腔单元。

6. 发明申请

WO2006108809A1 MEDICAL SKIN MOUNTABLE DEVICE AND SYSTEM 审中-公开
标题翻译：医疗皮肤安全装置和系统
公开(公告)号：WO2006108809A1
公开(公告)日：2006-10-19
申请号：PCT/EP2006/061444
申请日：2006-04-07
申请人： NOVO NORDISK A/S , HANSEN, Steffen , LARSEN, Bjørn, Gullak , MØLLER, Claus, Schmidt , NIELSEN, Ole, Christian , RADMER, Jim , PREUTHUN, Jan, Harald , SPARHOLT, Philip, Albert , ETHELFELD, Erik, Winkel , TEISEN-SIMONY, Claude , RØRVIG, Simon
发明人： HANSEN, Steffen , LARSEN, Bjørn, Gullak , MØLLER, Claus, Schmidt , NIELSEN, Ole, Christian , RADMER, Jim , PREUTHUN, Jan, Harald , SPARHOLT, Philip, Albert , ETHELFELD, Erik, Winkel , TEISEN-SIMONY, Claude , RØRVIG, Simon
IPC分类号： A61M5/158
CPC分类号： A61M5/172 , A61B5/145 , A61B5/6833 , A61M5/14248 , A61M2005/14252 , A61M2005/14268 , A61M2005/1581 , A61M2005/1585 , A61M2005/1587 , A61M2025/0266
摘要： A medical device is provided comprising a transcutaneous device unit and a process unit. The transcutaneous device unit may comprise a transcutaneous device for transporting a fluid through a skin portion of a subject, and a mounting surface adapted for application to the skin of the subject. The process unit may comprise a reservoir adapted to contain a fluid drug, the reservoir comprising an outlet means allowing the transcutaneous device to be arranged in fluid communication with an interior of the reservoir, and an expelling assembly for expelling a fluid drug out of the reservoir and through the skin of the subject via the transcutaneous device. The transcutaneous device unit and the process unit further comprise coupling means allowing the reservoir unit to be secured to the transcutaneous device unit in the situation of use. By this arrangement a two-unit system is provided which can be used in a convenient and cost-effective manner.
摘要翻译：提供了包括经皮装置单元和处理单元的医疗装置。经皮装置单元可以包括用于将流体输送通过受试者的皮肤部分的经皮装置和适于施用于受试者皮肤的安装表面。处理单元可以包括适于容纳流体药物的储存器，储存器包括允许经皮装置与储存器的内部流体连通的出口装置，以及用于将流体药物排出储存器的排出组件并通过经皮装置穿过受试者的皮肤。经皮装置单元和处理单元还包括在使用情况下允许储存器单元固定到经皮装置单元的联接装置。通过这种布置，提供了可以以便利且具有成本效益的方式使用的两单元系统。

7. 发明申请

WO2006114396A1 INJECTION DEVICE 审中-公开
标题翻译：注射装置
公开(公告)号：WO2006114396A1
公开(公告)日：2006-11-02
申请号：PCT/EP2006/061748
申请日：2006-04-21
申请人： NOVO NORDISK A/S , GLEJBØL, Kristian , LINNEBJERG, Steven , MØLLER, Claus, Schmidt , HANSEN, Michael, Ejstrup
发明人： GLEJBØL, Kristian , LINNEBJERG, Steven , MØLLER, Claus, Schmidt , HANSEN, Michael, Ejstrup
IPC分类号： A61M5/315
CPC分类号： A61M5/3158 , A61M5/31541 , A61M5/31551 , A61M5/31556 , A61M5/31558 , A61M5/3156 , A61M5/31561 , A61M5/31573 , A61M5/31575 , A61M5/31585 , A61M2005/3152
摘要： An injection device for injection of set doses of medicine from a cartridge has a nut (13) that is screwed up along a threaded piston rod (4) during a dose setting operation. The nut is screwed along the piston rod by rotating a dose setting member (17). A rotational coupling mechanism includes an axially displaceable coupling member (25) which is rotated as a function of axial displacement. During dose setting, the nut is allowed to rotate relative to the coupling member. During injection, the coupling member is rotationally locked to the nut. This provides a dose setting and injection mechanism wherein the nut member is both rotated during dose setting and during injection.
摘要翻译：用于从药筒注射设定剂量的药物的注射装置具有在剂量设定操作期间沿着螺纹活塞杆（4）拧紧的螺母（13）。通过旋转剂量设定构件（17）沿着活塞杆将螺母拧紧。旋转联接机构包括作为轴向位移的函数旋转的可轴向移动的联接构件（25）。在剂量设定期间，允许螺母相对于联接构件旋转。在注射期间，联接构件旋转地锁定到螺母。这提供了剂量设定和注射机制，其中螺母构件在剂量设定期间和注射期间都旋转。

8. 发明申请

WO2006114395A1 AN INJECTION DEVICE WITH A GEARBOX 审中-公开
标题翻译：具有齿轮箱的注射装置
公开(公告)号：WO2006114395A1
公开(公告)日：2006-11-02
申请号：PCT/EP2006/061747
申请日：2006-04-21
申请人： NOVO NORDISK A/S , GLEJBØL, Kristian , MØLLER, Claus, Schmidt , HANSEN, Michael, Ejstrup
发明人： GLEJBØL, Kristian , MØLLER, Claus, Schmidt , HANSEN, Michael, Ejstrup
IPC分类号： A61M5/315
CPC分类号： A61M5/3158 , A61M5/31541 , A61M5/31551 , A61M5/31558 , A61M5/3156 , A61M5/31561 , A61M5/31575 , A61M5/31585 , A61M5/31591 , A61M5/31593 , A61M2005/3152
摘要： An injection device for injection of set dose of liquid medicine from a cartridge has a piston rod (4, 104) / nut (3, 113) assembly where a nut is screwed up along a threaded piston rod during a dose setting operation. During administration of the set dose the nut is also screwed along the piston rod, thus making the piston rod / nut assembly either longer or shorter. During dose setting the nut is screwed along the piston rod by rotating a dose setting drum (17). An injection button is coupled to the piston rod with a gear wheel transmission (9, 109). Movement of the injection button causes a corresponding movement of the piston rod until the nut engages an abutment in the housing (1).
摘要翻译：用于从药筒注射剂量的液体药物的注射装置具有活塞杆（4,104）/螺母（3,113）组件，其中在剂量设定操作期间螺母沿螺纹活塞杆拧紧。在给药期间，螺母也沿着活塞杆拧紧，从而使活塞杆/螺母组件更长或更短。在剂量设定期间，通过旋转剂量设定鼓（17），将螺母沿活塞杆拧紧。注射按钮用齿轮传动装置（9,109）联接到活塞杆上。注射按钮的移动导致活塞杆的相应运动，直到螺母与壳体（1）中的邻接件接合。

9. 发明申请

WO2006089768A1 A DOSE SETTING MECHANISM FOR AN INJECTION DEVICE 审中-公开
标题翻译：用于注射装置的剂量设定机构
公开(公告)号：WO2006089768A1
公开(公告)日：2006-08-31
申请号：PCT/EP2006/001708
申请日：2006-02-24
申请人： NOVO NORDISK A/S , MØLLER, Claus, Schmidt
发明人： MØLLER, Claus, Schmidt
IPC分类号： A61M5/315 , A61M5/24 , A61M5/50
CPC分类号： A61M5/31541 , A61M5/24 , A61M5/31535 , A61M5/31538 , A61M5/31551 , A61M5/31575 , A61M5/31583 , A61M5/50
摘要： A dose setting mechanism for an injection device (1), e.g. for repetitive self -injection of e.g. insulin or growth hormone. The mechanism has a dose setting member, a driving element for causing a set dose to be injected, and a locking member (6) being connected to the driving element (3) . The position of the locking member (6) is indicative of the remaining amount of liquid in a cartridge (5). When the amount is below a predefined critical lower value, thelocking member (6) assumes a locking position where it prevents the dose setting member from being operated to set a dose. When the locking member (S) is not in the locking position the dose setting mechanism may be operated toset and inject a dose, even if injection of the set dose results in the remaining amount of liquid falling below the predefined critical lower value.
摘要翻译：用于注射装置（1）的剂量设定机构，例如，用于例如重复自我注入。胰岛素或生长激素。该机构具有剂量设定部件，用于引起设定剂量的驱动元件，以及与驱动元件（3）连接的锁定部件（6）。锁定构件（6）的位置指示筒（5）中液体的剩余量。当该量低于预定的临界较低值时，锁定构件（6）呈现锁定位置，其中防止剂量设定构件被操作以设定剂量。当锁定构件（S）不处于锁定位置时，即使喷射设定的剂量导致液体的剩余量低于预定临界较低值，也可以操作剂量设定机构来设定和注射剂量。

10. 发明申请

WO2006058883A2 INJECTION DEVICE 审中-公开
标题翻译：注射装置
公开(公告)号：WO2006058883A2
公开(公告)日：2006-06-08
申请号：PCT/EP2005/056313
申请日：2005-11-29
申请人： NOVO NORDISK A/S , RADMER, Bo , MØLLER, Claus, Schmidt , GROTH, Lars, Mørch , THØGERSEN, Klaus
发明人： RADMER, Bo , MØLLER, Claus, Schmidt , GROTH, Lars, Mørch , THØGERSEN, Klaus
IPC分类号： A61M5/315 , A61M5/24
CPC分类号： A61M5/31545 , A61M5/24 , A61M5/31528 , A61M5/31535 , A61M5/31541 , A61M5/31548 , A61M5/3155 , A61M5/31551 , A61M5/31558 , A61M5/31585 , A61M2005/2407 , A61M2005/3125 , A61M2005/3126
摘要： The invention concerns an injection device for apportioning set doses of a drug from a reservoir to a subject. The injection device comprises a housing having an interior thread formed as an outwardly pointing thread carried on an upstanding tower centrally located in the pen shaped device. This outwardly pointing thread forms a first thread connection with the interior thread of the rotatable scale drum. The injection device further comprises a driver for moving the piston rod forward when moved axially. The driver operates the piston rod through a second thread connection having a pitch different than the first thread connection.
摘要翻译：本发明涉及一种用于将药物的设定剂量从储存器分配给受试者的注射装置。注射装置包括具有内螺纹的壳体，该内螺纹形成为位于笔形装置中心的直立塔上的向外指向的线。这个向外指向的螺纹与可旋转的刻度鼓的内螺纹形成第一螺纹连接。注射装置还包括用于当轴向移动时将活塞杆向前移动的驱动器。驾驶员通过具有不同于第一螺纹连接的螺距的第二螺纹连接器来操作活塞杆。

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