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1. 发明申请

WO2006078318A3 IMMUNOGENIC COMPOSITIONS FOR GRAM POSITIVE BACTERIA SUCH AS STREPTOCOCCUS AGALACTIAE 审中-公开
标题翻译： AM AM E E E E E E E E E E E E E E E E E E E E E E E
公开(公告)号：WO2006078318A3
公开(公告)日：2008-10-30
申请号：PCT/US2005027239
申请日：2005-07-29
申请人： NOVARTIS VACCINES & DIAGNOSTIC , TELFORD JOHN L , GRANDI GUIDO , LAUER PETER , MORA MARIROSA , ROS IMMACULADA MARGARIT Y , MAIONE DOMENICO , BENSI GUILIANO , RINAUDO DANIELA , MASIGNANI VEGA , BAROCCHI MICHELLE , RAPPULOI RINO
发明人： TELFORD JOHN L , GRANDI GUIDO , LAUER PETER , MORA MARIROSA , ROS IMMACULADA MARGARIT Y , MAIONE DOMENICO , BENSI GUILIANO , RINAUDO DANIELA , MASIGNANI VEGA , BAROCCHI MICHELLE , RAPPULOI RINO
IPC分类号： A61K39/02
CPC分类号： A61K39/092 , A61K39/0208 , A61K39/05 , A61K39/08 , A61K39/085 , A61K39/09 , A61K39/095 , A61K2039/523 , C07K16/1267
摘要： The invention relates to the identification of a new adhesin islands within the genomes of several Group A and Group B Streptococcus serotypes and isolates. The adhesin islands are thought to encode surface proteins which are important in the bacteria's virulence. Thus, the adhesin island proteins of the invention may be used in immunogenic compositions for prophylactic or therapeutic immunization against GAS or GBS infection. For example, the invention may include an immunogenic composition comprising one or more of the discovered adhesin island proteins.
摘要翻译：本发明涉及鉴定几组A组和B组链球菌血清型和分离株的基因组中的新粘附素岛。粘附素岛被认为编码在细菌的毒力中重要的表面蛋白质。因此，本发明的粘附素岛蛋白可用于免疫原性组合物，用于针对GAS或GBS感染的预防性或治疗性免疫。例如，本发明可以包括包含一种或多种所发现的粘附素岛蛋白的免疫原性组合物。

2. 发明公开

EP1784211A4 IMMUNOGENIC COMPOSITIONS FOR GRAM POSITIVE BACTERIA SUCH AS STREPTOCOCCUS AGALACTIAE 审中-公开
标题翻译：用于革兰氏阳性菌AS无乳链球菌免疫原性组合物
公开(公告)号：EP1784211A4
公开(公告)日：2010-06-30
申请号：EP05856900
申请日：2005-07-29
申请人： NOVARTIS VACCINES & DIAGNOSTIC
发明人： TELFORD JOHN L , GRANDI GUIDO , LAUER PETER , MORA MARIROSA , ROS IMMACULADA MARGARIT Y , MAIONE DOMENICO , BENSI GUILIANO , RINAUDO DANIELA , MASIGNANI VEGA , BAROCCHI MICHELLE , RAPPULOI RINO
IPC分类号： A61K39/02
CPC分类号： A61K39/092 , A61K39/0208 , A61K39/05 , A61K39/08 , A61K39/085 , A61K39/09 , A61K39/095 , A61K2039/523 , C07K16/1267
摘要： The invention relates to the identification of a new adhesin islands within the genomes of several Group A and Group B Streptococcus serotypes and isolates. The adhesin islands are thought to encode surface proteins which are important in the bacteria's virulence. Thus, the adhesin island proteins of the invention may be used in immunogenic compositions for prophylactic or therapeutic immunization against GAS or GBS infection. For example, the invention may include an immunogenic composition comprising one or more of the discovered adhesin island proteins.

3. 发明申请

WO2009127403A3 PRESSURE-REDUCING SEAT VALVE AND LOCKING CIRCUIT 审中-公开
标题翻译：减压阀阀片和SPAN电路
公开(公告)号：WO2009127403A3
公开(公告)日：2009-12-10
申请号：PCT/EP2009002752
申请日：2009-04-15
申请人： BOSCH GMBH ROBERT , FISCHER STEFFEN , LAUER PETER
发明人： FISCHER STEFFEN , LAUER PETER
IPC分类号： G05D16/10
CPC分类号： G05D16/10
摘要： The invention provides a pressure reducing seat valve and locking circuits. A pressure means may be supplied to a supply connection at a predetermined pressure by means of the pressure reducing valve in a seat valve configuration. The pressure reducing valve has a valve piston being movable opposite a seat surface that is disposed on a housing in a fixed manner, and which has a first control surface at which said valve piston is forced by the pressure in the supply connection in the sense of a locking movement against the seat surface, said valve piston being forced by way of a control spring in the sense of an opening movement, wherein the valve piston is forced in the sense of a locking movement by way of a second control surface subjected to the pressure in the supply connection. The pressure reducing function and a check valve may be integrated into such a seat valve for a pre-opening of the pressure means connection between the secondary pressure and the primary pressure. A locking circuit according to the invention having such pressure reducing valves and a directional seat valve enables the minimizing of the hydraulic power loss, and the reducing of the effort for changeable locking pressures.
摘要翻译：根据本发明的一个Druckreduziersitzventil和钳位电路提供与此有关。通过减压阀在座椅设计压力介质可以从一个电源端被馈送以预定的压力的负载连接。减压阀具有阀活塞，该活塞可相对于壳体固定的座移动，并具有第一控制表面，其所经受的负载端口中的压力抵靠座面和其在由控制弹簧在打开运动的感作用的闭合运动感，其中，所述阀活塞在由在电源端的压力作用在关闭运动的感暴露的第二控制表面。在这样的座阀，该压力限制功能和用于预打开所述低压流体连接部的止回阀可以在次级压力和初级压力之间集成在一起。根据本发明的具有这样的减压阀和一个方向控制阀的钳位电路允许最小化所述液压功率损耗和减小在可变夹紧压力的努力。

4. 发明申请

WO03014603A3 DAMPING NOZZLE ARRANGEMENT 审中-公开
标题翻译： LOSS喷嘴排列
公开(公告)号：WO03014603A3
公开(公告)日：2003-05-30
申请号：PCT/DE0202664
申请日：2002-07-19
申请人： BOSCH REXROTH AG , LAUER PETER , MEYER KARL
发明人： LAUER PETER , MEYER KARL
IPC分类号： A61M39/00 , F16K47/08
CPC分类号： F16K47/08
摘要： The invention relates to a damping nozzle arrangement for hydraulic pressurizing medium in which a nozzle body (11) is placed inside a pressurizing medium channel (12). The nozzle body is provided with an axial boring (22), which starts from a front side (19)and does not completely pass through the nozzle body. The nozzle body is additionally provided with a radial boring (21) that connects the axial boring to an annular space (18) formed between the nozzle body and the pressurizing medium channel. Two nozzles having a rectangular cross-section are situated between the annular space and the pressurizing medium channel and they determine the throttling action of the damping nozzle arrangement (not shown). The invention provides a damping nozzle arrangement that is easy to produce even when requiring a high throttling action. Instead of both nozzles having a rectangular cross-section, the outside diameter of the nozzle body and the inside diameter of the pressurizing medium channel surrounding the same are provided so that an annular gap, which is delimited in an axial direction, is formed between the nozzle body and the pressurizing medium channel. The nozzle body is tightly held inside the pressurizing medium channel. Damping nozzle arrangements of this type are used for damping hydraulic systems that have a tendency to vibrate.
摘要翻译：在用于液压介质喷嘴体11的阻尼喷嘴组件被布置在压力介质通道12 喷嘴主体是从端面轴向的19孔22不完全渗透喷嘴主体设置有外向。喷嘴主体另外设置有一个径向孔21连接与所述喷嘴主体和所述压力介质通道18环之间形成的空间的轴向孔环空和流体通路之间的两个喷嘴被布置成与rechteckförmigern横截面确定所述阻尼喷嘴组件的节流作用。它被赋予一个阻尼喷嘴组件其制造即使在大节流效应简单。代替两个喷嘴具有矩形的横截面，所述喷嘴体和周围的压力介质通道的内径的外径的尺寸使得一个在所述喷嘴主体和所述压力介质通道之间在轴向上有限环形间隙形成。喷嘴主体是在流体通道保持。这种喷嘴组件被用于阻尼趋于摆动液压系统。

5. 发明授权

US652279A Bolt for double doors. 失效
标题翻译：双门开关。
公开(公告)号：US652279A
公开(公告)日：1900-06-26
申请号：US1899733010
申请日：1899-10-09
申请人： LAUER PETER
发明人： LAUER PETER
CPC分类号： E05C9/043 , E05B7/00 , Y10S70/65 , Y10T292/0839

6. 发明申请

WO0236967A3 PILOT-OPERATED PRESSURE SHUT-OFF VALVE 审中-公开
标题翻译：先导式关闭
公开(公告)号：WO0236967A3
公开(公告)日：2003-02-13
申请号：PCT/EP0112094
申请日：2001-10-19
申请人： BOSCH REXROTH AG , KRENZER GUENTER , MEYER KARL JOSEF , LAUER PETER
发明人： KRENZER GUENTER , MEYER KARL JOSEF , LAUER PETER
IPC分类号： F16K3/24 , F15B1/027 , F15B11/08 , F16K31/363
CPC分类号： F15B1/0275 , Y10T137/2625 , Y10T137/263 , Y10T137/2635 , Y10T137/7766 , Y10T137/777
摘要： The invention relates to a pilot-operated pressure shut-off valve with a main control piston (20), by means of which an inlet (12), which can introduce a pressure medium to a hydraulic system, is connected to a drain (13), on reaching an upper system limiting pressure and adopting a first switched position and is separated from said drain (13), on reaching a lower system limiting pressure and adopting a second switched position. The pressure shut-off valve has a pilot valve arrangement (11). On such a pressure shut-off valve, the pilot valve arrangement should be compact and of simple construction, in contrast to pilot valve arrangements on a pressure shut-off valve where the upper system pressure and the lower system pressure can not be set independently of each other and should be exchangeable and produced economically. According to the invention, the above is achieved, whereby both pilot pistons (44, 48), both pilot springs (45, 49) and both adjuster screws (78, 80) are arranged concentrically within each other, whereby both pilot pistons (44, 48) are mechanically adjustable completely separately from each other.
摘要翻译：所述Erfinderung涉及一种导向操作压力切断与具有入口（12），通过该zufühbar的液压系统压力装置连接的主控制活塞（20），当在液压系统中的上层系统极限压力以第一开关位置与漏极（13）和分离到达由Einnnahme较低的系统极限压力从漏极（13）的第二位置的围巾。压力截止阀具有先导阀组件（11）。在这种Druckabschalventil先导阀装置（11）旨在是紧凑和简单的结构，对一个Druckabschalventils，其中所述上系统极限压力和更低的系统极限压力不能彼此unabhändig被设置为可更换的，并廉价地制造的先导阀安排。根据本发明这是这样实现在所述两个导频的活塞（44，48），所述两个导频的弹簧（45，49）和两个调节螺钉（78，80）同心地布置一个在另一个内，其中，所述两个导频的活塞（44，48）machanisch完全是可调节的unabhändig彼此。

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