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1. 发明申请

WO2003078404A1 PYRIMIDINE DERIVATIVES 审中-公开
标题翻译：吡嗪衍生物
公开(公告)号：WO2003078404A1
公开(公告)日：2003-09-25
申请号：PCT/EP2003/002710
申请日：2003-03-14
申请人： NOVARTIS AG , NOVARTIS PHARMA GMBH , BAENTELI, Rolf , ZENKE, Gerhard , COOKE, Nigel, Graham , DUTHALER, Rudolf , THOMA, Gebhard , VON MATT, Anette , HONDA, Toshiyuki , MATSUURA, Naoko , NONOMURA, Kazuhiko , OHMORI, Osamu , UMEMURA, Ichiro , HINTERDING, Klaus , PAPAGEORGIOU, Christos
发明人： BAENTELI, Rolf , ZENKE, Gerhard , COOKE, Nigel, Graham , DUTHALER, Rudolf , THOMA, Gebhard , VON MATT, Anette , HONDA, Toshiyuki , MATSUURA, Naoko , NONOMURA, Kazuhiko , OHMORI, Osamu , UMEMURA, Ichiro , HINTERDING, Klaus , PAPAGEORGIOU, Christos
IPC分类号： C07D239/48
CPC分类号： C07D239/48 , A61K31/505 , A61K31/506 , A61K31/5377 , A61K31/55 , A61K45/06 , C07D231/12 , C07D233/56 , C07D249/08 , C07D401/12 , C07D401/14 , C07D403/12 , C07D417/12
摘要： There are provided compounds of formula (I), wherein X, R 1 , R 2 , R 3 , R 4 , R 5 , R 6 , R 7 , R 8 and R 9 are as indicated in claim 1, useful in disorders where ZAP-70 and/or Syk inhibition plays a role or caused by a malfunction of signal cascades connected with FAK.
摘要翻译：提供式（I）化合物，其中X，R 1，R 2，R 3，R 4，R 5，R 6，R 7， 8＆gt;和R 9如权利要求1所述，其用于ZAP-70和/或Syk抑制起作用或由与FAK连接的信号级联故障引起的疾病中。

2. 发明申请

WO2002076995A2 2-AMINO-PROPANOL DERIVATIVES 审中-公开
标题翻译： 2-氨基丙酰胺衍生物
公开(公告)号：WO2002076995A2
公开(公告)日：2002-10-03
申请号：PCT/EP2002/003389
申请日：2002-03-26
申请人： NOVARTIS AG , NOVARTIS-ERFINDUNGEN VERWALTUNGSGESELLSCHAFT M.B.H. , ALBERT, Rainer , BAUMRUKER, Thomas , BRINKMANN, Volker , COTTENS, Sylvain , PAPAGEORGIOU, Christos , PRIESCHL-STRASSMAYR, Eva, Erika , HINTERDING, Klaus
发明人： ALBERT, Rainer , BAUMRUKER, Thomas , BRINKMANN, Volker , COTTENS, Sylvain , PAPAGEORGIOU, Christos , PRIESCHL-STRASSMAYR, Eva, Erika , HINTERDING, Klaus
IPC分类号： C07F9/09
CPC分类号： C07F9/65744 , C07B2200/07 , C07C217/64 , C07C225/16 , C07C271/16 , C07C2601/14 , C07F9/094 , C07F9/113 , C07F9/12
摘要： Compounds of formula (i), wherein m, R, R 1 and R 3 to R 6 are as defined in the specification, m, is 1, 2 or 3 and X is O or a direct bond, and the corresponding unphosporylated compounds have interesting properties, e.g. immunosuppressive properties.
摘要翻译：式（I）的化合物，其中m，R，R 1和R 3至R 6如本说明书中所定义，m为1,2或3，X为O或直接键，相应的未末端化合物具有有趣的性质，例如免疫抑制性质。

3. 发明公开

EP1377593A2 2-AMINO-PROPANOL DERIVATIVES 有权
标题翻译： 2-氨基丙醇衍生物
公开(公告)号：EP1377593A2
公开(公告)日：2004-01-07
申请号：EP02727484.4
申请日：2002-03-26
申请人： Novartis AG , Novartis Pharma GmbH
发明人： ALBERT, Rainer , BAUMRUKER, Thomas , BRINKMANN, Volker , COTTENS, Sylvain , PAPAGEORGIOU, Christos , PRIESCHL-STRASSMAYR, Eva, Erika , HINTERDING, Klaus
IPC分类号： C07F9/09 , A61K31/661 , A61K31/137 , A61P31/00 , A61P17/00 , C07C225/16 , C07C271/16 , C07C217/64 , A61P19/00
CPC分类号： C07F9/65744 , C07B2200/07 , C07C217/64 , C07C225/16 , C07C271/16 , C07C2601/14 , C07F9/094 , C07F9/113 , C07F9/12
摘要： Compounds of formula (I), wherein m, R, R1 and R3 to R6 are as defined in the specification, m, is 1, 2 or 3 and X is O or a direct bond, and the corresponding unphosporylated compounds have interesting properties, e.g. immunosuppressive properties.

4. 发明授权

EP1377593B1 2-AMINO-PROPANOL DERIVATIVES 有权
标题翻译： 2-氨基丙醇衍生物
公开(公告)号：EP1377593B1
公开(公告)日：2005-12-28
申请号：EP02727484.4
申请日：2002-03-26
申请人： Novartis AG , Novartis Pharma GmbH
发明人： ALBERT, Rainer , BAUMRUKER, Thomas , BRINKMANN, Volker , COTTENS, Sylvain , PAPAGEORGIOU, Christos , PRIESCHL-STRASSMAYR, Eva, Erika , HINTERDING, Klaus
IPC分类号： C07F9/09 , A61K31/661 , A61K31/137 , A61P31/00 , A61P17/00 , C07C225/16 , C07C271/16 , C07C217/64 , A61P19/00
CPC分类号： C07F9/65744 , C07B2200/07 , C07C217/64 , C07C225/16 , C07C271/16 , C07C2601/14 , C07F9/094 , C07F9/113 , C07F9/12
摘要： Compounds of formula (I), wherein m, R, R1 and R3 to R6 are as defined in the specification, m, is 1, 2 or 3 and X is O or a direct bond, and the corresponding unphosporylated compounds have interesting properties, e.g. immunosuppressive properties.
摘要翻译：其中m，R，R 1和R 3至R 6的式I化合物如说明书中所定义，m为1， 2或3，X是O或直接键合，并且相应的未磷酸化化合物具有有趣的性质，例如免疫抑制性质。

5. 发明授权

EP1487805B1 PYRIMIDINE DERIVATIVES 有权转让
标题翻译：嘧啶衍生物
公开(公告)号：EP1487805B1
公开(公告)日：2012-07-04
申请号：EP03744366.0
申请日：2003-03-14
申请人： Novartis AG , Novartis Pharma GmbH
发明人： BAENTELI, Rolf , ZENKE, Gerhard , COOKE, Nigel, Graham , DUTHALER, Rudolf , THOMA, Gebhard , VON MATT, Anette , HONDA, Toshiyuki , MATSUURA, Naoko , NONOMURA, Kazuhiko , OHMORI, Osamu , UMEMURA, Ichiro , HINTERDING, Klaus , PAPAGEORGIOU, Christos
IPC分类号： C07D239/48 , A61K31/505 , A61P35/04
CPC分类号： C07D239/48 , A61K31/505 , A61K31/506 , A61K31/5377 , A61K31/55 , A61K45/06 , C07D231/12 , C07D233/56 , C07D249/08 , C07D401/12 , C07D401/14 , C07D403/12 , C07D417/12
摘要： There are provided compounds of formula (I), wherein X, R1, R2, R3, R4, R5, R6, R7, R8 and R9 are as indicated in claim 1, useful in disorders where ZAP-70 and/or Syk inhibition plays a role or caused by a malfunction of signal cascades connected with FAK.

6. 发明申请

WO2015052544A2 ENCLOSED SOLAR CHIMNEY POWER PLANT 审中-公开
标题翻译：封闭太阳能烟囱发电厂
公开(公告)号：WO2015052544A2
公开(公告)日：2015-04-16
申请号：PCT/GR2014/000059
申请日：2014-10-06
申请人： PAPAGEORGIOU, Christos
发明人： PAPAGEORGIOU, Christos
IPC分类号： F03G6/00
CPC分类号： F03G6/045 , Y02B10/20 , Y02B10/30 , Y02B10/70 , Y02E10/465
摘要： The invention is named enclosed solar chimney power plant by the way of its solar collector (greenhouse) construction. The enclosed solar collector (greenhouse) (1.1) has a transparent roof (1.2) and it is surrounded by a peripheral vertical wall (1.3). On this peripheral vertical wall there are circular openings (1.4) through which the incoming air stream is entering, replacing the warm air that is escaping continuously through the solar chimney. The incoming air stream in each opening (1.4) is forcing to rotate its corresponding air turbine (2.1) and its engaged electric generator (2.2) generating electricity. In each opening there is an electromechanical air blocking system (2.3) which can release or block the entering air stream and may also connect or disconnect the electric generator (2.2) to the grid.
摘要翻译：本发明以太阳能收集器（温室）施工方式命名为封闭式太阳能烟囱发电厂。封闭的太阳能收集器（温室）（1.1）具有透明屋顶（1.2），并被周边垂直壁（1.3）包围。在这个外围的垂直墙上有一个圆形的开口（1.4），进入的空气流通过这个开口，更换了通过太阳能烟囱连续排出的暖空气。每个开口（1.4）中的进入空气流迫使其对应的空气涡轮机（2.1）及其接合的发电机（2.2）转动。在每个开口中都有一个机电空气阻塞系统（2.3），可以释放或阻挡进入的空气流，并且还可以将发电机（2.2）连接或断开到电网。

7. 发明申请

WO2004085846A1 FLOATING SOLAR CHIMNEY 审中-公开
标题翻译：浮动太阳能烟囱
公开(公告)号：WO2004085846A1
公开(公告)日：2004-10-07
申请号：PCT/GR2003/000037
申请日：2003-09-08
申请人： PAPAGEORGIOU, Christos
发明人： PAPAGEORGIOU, Christos
IPC分类号： F03G6/04
CPC分类号： F03G6/045 , F03D1/04 , F05B2240/131 , F05B2240/922 , F05B2240/93 , Y02E10/465 , Y02E10/72
摘要： The floating solar chimney is composed by three parts as appear in figure 1(a). The Main Chimney (1.1). The Heavy Base (1.2). The Folding Lower Part (1.3). The main chimney (1.1) is composed by cylindrical balloon rings D1 (fig 2) full of non flammable light gas. This cylindrical balloon rings Dl are tied up between them with the help of supporting rings D2 (fig 3) so that they form a compact thermo insulated cylindrical chimney. The compact parts of the main chimney are fastened on the mobile heavy base. The successive compact parts are separated with rings D 1 full from environmental air that can go in and out, so that the dynamic independence of the successive parts is ensured. The main chimney can float; self lifted and is fastened on the seat (1.4) by the mobile heavy base (1.2). In the lower part of its heavy base is fastened the folding lower part of solar chimney (type accordion, 1.3). The air can enter and come out freely from the rings of folding lower part in order that the floating solar chimney can receive any suitable decline in order to withstand the exterior winds (fig 1b).
摘要翻译：浮动太阳能烟囱由图1（a）所示的三部分组成。主烟囱（1.1）。重基（1.2）。折叠下部（1.3）。主烟囱（1.1）由充满非易燃轻质气体的圆柱形球囊D1（图2）组成。借助于支撑环D2（图3），将这个圆柱形气球环D1捆绑在它们之间，使得它们形成紧凑的隔热的圆柱形烟囱。主烟囱的紧凑部分紧固在移动式重型底座上。连续的紧凑部件与可以进出的环境空气的环D 1分开，从而确保连续部件的动态独立性。主烟囱可以漂浮; 通过移动式重型底座（1.2）自动抬起并固定在座椅（1.4）上。在其底部的下部固定太阳能烟囱的折叠下部（类型手风琴，1.3）。空气可以从折叠下部的环自由进出，以便浮式太阳能烟囱可以接受任何适当的下降以承受外部风（图1b）。

8. 发明公开

EP1487805A1 PYRIMIDINE DERIVATIVES 有权转让
标题翻译：嘧啶衍生物
公开(公告)号：EP1487805A1
公开(公告)日：2004-12-22
申请号：EP03744366.0
申请日：2003-03-14
申请人： Novartis AG
发明人： BAENTELI, Rolf , ZENKE, Gerhard , COOKE, Nigel, Graham , DUTHALER, Rudolf , THOMA, Gebhard , VON MATT, Anette , HONDA, Toshiyuki , MATSUURA, Naoko , NONOMURA, Kazuhiko , OHMORI, Osamu , UMEMURA, Ichiro , HINTERDING, Klaus , PAPAGEORGIOU, Christos
IPC分类号： C07D239/48 , A61K31/505 , A61P35/04
CPC分类号： C07D239/48 , A61K31/505 , A61K31/506 , A61K31/5377 , A61K31/55 , A61K45/06 , C07D231/12 , C07D233/56 , C07D249/08 , C07D401/12 , C07D401/14 , C07D403/12 , C07D417/12
摘要： There are provided compounds of formula (I), wherein X, R1, R2, R3, R4, R5, R6, R7, R8 and R9 are as indicated in claim 1, useful in disorders where ZAP-70 and/or Syk inhibition plays a role or caused by a malfunction of signal cascades connected with FAK.
摘要翻译：提供式（I）化合物，其中X，R 1，R 2，R 3，R 4，R 5，R 6，R 7，R 8和R 9如权利要求1中所示，可用于ZAP-70和/ 一个角色或由FAK连接的信号级联发生故障引起。

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