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1. 发明专利

DE69026361D1 未知
公开(公告)号：DE69026361D1
公开(公告)日：1996-05-09
申请号：DE69026361
申请日：1990-12-21
申请人： NITTO DENKO CORP , TOA EIYO LTD
发明人： AKEMI HITOSHI , OTSUKA SABURO , KINOSHITA TAKASHI , HOSAKA YOSHIFUMI , NAKANO YOSHIHISA
IPC分类号： A61K9/70 , A61K31/34 , A61L15/44

2. 发明专利

CA2157754A1 PERCUTANEOUS ABSORPTION PREPARATION 未知
公开(公告)号：CA2157754A1
公开(公告)日：1996-03-15
申请号：CA2157754
申请日：1995-09-07
申请人： NITTO DENKO CORP , TOA EIYO LTD
发明人： AKEMI HITOSHI , MURAOKA TAKATERU , HIGASHIO KAZUHIRO , OTSUKA SABURO , KINOSHITA TAKASHI
IPC分类号： A61K9/70 , A61K31/34 , A61K47/14 , A61P9/08 , A61P9/10 , A61K47/30
摘要： A percutaneous absorption preparation for use in the administration of isosorbide dinitrate (ISDN) as a coronary vasodilator into the living body by percutaneous absorption, which has excellent adhesion to the skin and does not cause pain and damage to stratum corneum when peeled off, is disclosed. The pressure-sensitive adhesive layer comprises an acrylic copolymer prepared by copolymerization of a monomer mixture comprising a (meth)acrylic acid alkyl ester and a functional monomer as the essential components, a fatty acid ester having a specified number of carbon atoms, a monoglyceride having a specified number of carbon atoms, and ISDN, and the pressure-sensitive adhesive layer is crosslinked. Since its skin adhesive property is improved by the inclusion of the monoglyceride, release of ISDN is improved and the area of the preparation can be decreased.

3. 发明专利

ES2139806T3 未知
公开(公告)号：ES2139806T3
公开(公告)日：2000-02-16
申请号：ES95114128
申请日：1995-09-08
申请人： NITTO DENKO CORP , TOA EIYO LTD
发明人： AKEMI HITOSHI , MURAOKA TAKATERU , HIGASHIO KAZUHIRO , OTSUKA SABURO , KINOSHITA TAKASHI
IPC分类号： A61K9/70 , A61K31/34 , A61K47/14 , A61P9/08 , A61P9/10 , A61K47/32

4. 发明专利

DE69514178D1 未知
公开(公告)号：DE69514178D1
公开(公告)日：2000-02-03
申请号：DE69514178
申请日：1995-09-08
申请人： NITTO DENKO CORP , TOA EIYO LTD
发明人： AKEMI HITOSHI , MURAOKA TAKATERU , HIGASHIO KAZUHIRO , OTSUKA SABURO , KINOSHITA TAKASHI
IPC分类号： A61K9/70 , A61K31/34 , A61K47/14 , A61P9/08 , A61P9/10 , A61K47/32

5. 发明专利

DE69514178T2 未知
公开(公告)号：DE69514178T2
公开(公告)日：2000-05-31
申请号：DE69514178
申请日：1995-09-08
申请人： NITTO DENKO CORP , TOA EIYO LTD
发明人： AKEMI HITOSHI , MURAOKA TAKATERU , HIGASHIO KAZUHIRO , OTSUKA SABURO , KINOSHITA TAKASHI
IPC分类号： A61K9/70 , A61K31/34 , A61K47/14 , A61P9/08 , A61P9/10 , A61K47/32

6. 发明专利

DE69026361T2 未知
公开(公告)号：DE69026361T2
公开(公告)日：1996-08-14
申请号：DE69026361
申请日：1990-12-21
申请人： NITTO DENKO CORP , TOA EIYO LTD
发明人： AKEMI HITOSHI , OTSUKA SABURO , KINOSHITA TAKASHI , HOSAKA YOSHIFUMI , NAKANO YOSHIHISA
IPC分类号： A61K9/70 , A61K31/34 , A61L15/44

7. 发明专利

JPH03223212A GEL PREPARATION FOR TRANSCUTANEOUS ABSORPTION 失效
公开(公告)号：JPH03223212A
公开(公告)日：1991-10-02
申请号：JP23738490
申请日：1990-09-06
申请人： NITTO DENKO CORP , TOA EIYO LTD
发明人： AKEMI HITOSHI , OTSUKA SABURO , KINOSHITA TAKASHI , HOSAKA YOSHIFUMI , NAKANO YOSHIHISA
IPC分类号： A61K9/70 , A61K31/34 , A61K47/32 , C08L33/04 , C08L33/08
摘要： PURPOSE:To obtain a gel preparation for transcutaneous absorption having well-balanced skin adhesivity and skin stimulation by including an acrylic acid ester polymer and a large amount of a liquid component compatible to the polymer at a specific ratio in a crosslinked gel layer containing isosorbide dinitrate. CONSTITUTION:The objective gel preparation for transcutaneous absorption is produced by compounding (A) isosorbide dinitrate with (B) an acrylic acid ester polymer having high stability and releasability to the component A, preferably an acrylic copolymer produced by copolymerizing an alkyl (meth)acrylate and (meth)acrylic acid and (C) a liquid component compatible to the component B at a weight ratio (B:C) of 1.0:(0.25-2.0), crosslinking the composition and forming the crosslinked gel layer on one surface of a substrate. The preparation can be peeled off from the applied skin while giving little pain or skin irritation caused by the bonding force of the preparation. It has proper and balanced skin adhesivity and non-stimulating property to the skin and exhibits sufficient effect on the prevention of fit of e.g. stenocardia.

8. 发明申请

WO2005032401A3 PRESSURE-SENSITIVE ADHESIVE SHEET FOR APPLICATION TO SKIN 审中-公开
标题翻译：用于皮肤的压敏胶粘片
公开(公告)号：WO2005032401A3
公开(公告)日：2005-06-30
申请号：PCT/JP2004014683
申请日：2004-09-29
申请人： NITTO DENKO CORP , KANEKA CORP , HAMADA MASASHI , KINOSHITA TAKASHI , FURUMORI KENJI , UEDA KAZUHIKO , KOMITSU SHINTARO
发明人： HAMADA MASASHI , KINOSHITA TAKASHI , FURUMORI KENJI , UEDA KAZUHIKO , KOMITSU SHINTARO
IPC分类号： A61K9/70 , A61F20060101 , A61K47/30 , A61K47/32 , A61K47/34 , A61L15/00 , A61L15/58
CPC分类号： A61K9/7023 , A61L15/58 , Y10T428/28 , Y10T428/2852 , Y10T428/2878 , C08L83/04 , C08L71/02
摘要： A pressure-sensitive adhesive sheet for application to the skin which has a pressure-sensitive adhesive layer which can be formed without using an organic solvent, has satisfactory adhesion to the skin, and is extremely reduced in skin irritation and damage to the horny layer. The pressure-sensitive adhesive sheet for application to the skin comprises a substrate and a pressure-sensitive adhesive layer superposed on the substrate, the pressure-sensitive adhesive layer being one obtained by curing a pressure-sensitive adhesive composition comprising a polyether polymer (A) having at least one terminal alkenyl group, a compound (B) having one to ten hydrosilyl groups per molecule, and a hydrosilylation catalyst (C).
摘要翻译：具有可以不使用有机溶剂而形成的压敏胶粘剂层的用于皮肤的压敏胶粘片具有令人满意的对皮肤的粘附性，并且对角质层的皮肤刺激性和损伤极度降低。用于皮肤的压敏粘合剂片包括基材和叠加在基材上的压敏粘合剂层，所述压敏粘合剂层是通过固化包含聚醚聚合物（A）的压敏粘合剂组合物而获得的粘合剂层，具有至少一个末端烯基的化合物，每分子具有1至10个氢化硅烷基的化合物（B）和氢化硅烷化催化剂（C）。

9. 发明申请

WO9937336B1 SUBSTRATE FOR ADHESIVE DRESSING 审中-公开
标题翻译：胶粘剂基料
公开(公告)号：WO9937336B1
公开(公告)日：1999-11-25
申请号：PCT/JP9900189
申请日：1999-01-20
申请人： NITTO DENKO CORP , OHIRA OSAMU , KINOSHITA TAKASHI , SASAKI YASUYUKI , KOUSAKA TAKAHIRO
发明人： OHIRA OSAMU , KINOSHITA TAKASHI , SASAKI YASUYUKI , KOUSAKA TAKAHIRO
IPC分类号： A61F13/02 , A61L15/24 , A61L15/58
CPC分类号： A61L15/24 , A61L15/58 , C08L31/04
摘要： An EVA-based substrate for an adhesive dressing satisfying characteristics such as flexibility, stretchability, skin follow-up property, mechanical strength, curl preventing property and the like is provided as a substitute for a polyvinyl chloride-base substrate and also provided are a medical adhesive dressing and an adhesive tape, e.g., first-aid adhesive tape using the same. A substrate for an adhesive dressing comprises an ethylene/vinyl acetate copolymer having a weight average molecular weight of 1 x 10 to 1 x 10 , a molecular weight distribution of 4.0 or less, a melt flow rate of 3.0 g/10 minutes or less, and a vinyl acetate content of 15 to 28 % by weight is provided and medical adhesive dressings can be prepared by forming a pressure-sensitive adhesive layer on one surface of the substrate. Further, an adhesive tape can be made by arranging a pad for covering and protecting a wounded portion, on a part of a surface of the pressure-sensitive adhesive layer.
摘要翻译：作为聚氯乙烯系基材的代替品，提供满足柔软性，拉伸性，皮肤追随性，机械强度，防卷曲性等特性的粘合剂敷料用EVA基基材，并且还提供医疗用粘合剂敷料和胶带，例如使用它的急救胶带。用于粘合剂敷料的基材包含重均分子量为1×10 4至1×10 5，分子量分布为4.0或更低，熔体流动速率为3.0克/分钟的乙烯/乙酸乙烯酯共聚物 / 10分钟或更少，并且乙酸乙烯酯含量为15至28重量％，并且可以通过在基材的一个表面上形成压敏粘合剂层来制备医用粘合剂敷料。此外，可以通过在压敏粘合剂层的表面的一部分上设置用于覆盖和保护卷绕部分的衬垫来制造粘合带。

10. 发明申请

WO9937336A2 SUBSTRATE FOR ADHESIVE DRESSING, AND MEDICAL ADHESIVE DRESSING AND ADHESIVE TAPE USING THE SAME 审中-公开
标题翻译：粘合用基材，医用胶粘剂和胶粘带
公开(公告)号：WO9937336A2
公开(公告)日：1999-07-29
申请号：PCT/JP9900189
申请日：1999-01-20
申请人： NITTO DENKO CORP , OHIRA OSAMU , KINOSHITA TAKASHI , SASAKI YASUYUKI , KOUSAKA TAKAHIRO
发明人： OHIRA OSAMU , KINOSHITA TAKASHI , SASAKI YASUYUKI , KOUSAKA TAKAHIRO
IPC分类号： A61F13/02 , A61L15/24 , A61L15/58 , A61L15/00
CPC分类号： A61L15/24 , A61L15/58 , C08L31/04
摘要： An EVA-based substrate for an adhesive dressing satisfying characteristics such as flexibility, stretchability, skin follow-up property, mechanical strength, curl preventing property and the like is provided as a substitute for a polyvinyl chloride-base substrate and also provided are a medical adhesive dressing and an adhesive tape, e.g., first-aid adhesive tape using the same. A substrate for an adhesive dressing comprises an ethylene/vinyl acetate copolymer having a weight average molecular weight of 1 x 10 to 1 x 10 , a molecular weight distribution of 4.0 or less, a melt flow rate of 3.0 g/10 minutes or less, and a vinyl acetate content of 15 to 28 % by weight is provided and medical adhesive dressings can be prepared by forming a pressure-sensitive adhesive layer on one surface of the substrate. Further, an adhesive tape can be made by arranging a pad for covering and protecting a wounded portion, on a part of a surface of the pressure-sensitive adhesive layer.
摘要翻译：提供了一种用于粘合剂的基于EVA的基材，其可满足柔性，拉伸性，皮肤随动性，机械强度，卷曲防止性等特性，作为聚氯乙烯基底的替代物，并且还提供医用粘合剂和粘合带，例如使用其的急救胶带。用于粘合敷料的基材包括重均分子量为1×10 4至1×10 5，分子量分布为4.0或更小，熔体流动速率为3.0g的乙烯/乙酸乙烯酯共聚物 / 10分钟以下，乙酸乙烯酯的含量为15〜28重量％，通过在基材的一个面上形成压敏粘合剂层，可以制备医用粘合剂敷料。此外，粘合带可以通过在压敏粘合剂层的一部分表面上设置用于覆盖和保护受伤部分的垫来制成。

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