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1. 发明申请

WO2002088310A2 COBRA GENE AND USES THEREOF 审中-公开
标题翻译： COBRA基因及其用途
公开(公告)号：WO2002088310A2
公开(公告)日：2002-11-07
申请号：PCT/US2002/012956
申请日：2002-04-25
申请人： NEW YORK UNIVERSITY , BENFEY, Philip, N. , SCHINDELMAN, Gary
发明人： BENFEY, Philip, N. , SCHINDELMAN, Gary
IPC分类号： C12N
CPC分类号： C07K14/415 , C12N15/8242 , C12N15/8261 , C12N15/8271 , Y02A40/146
摘要： A method by which many plants control organ shape is by regulated, differential cellular expansion. A gene invloved in regulating the expansion of plants cells, such as Arabidopsis thaliana root cells is COBRA which encodes a protein with a putative GPI anchor. Plants comprising altered root morphologies may be produced by control of COBRA activity. For example, roots which lack COBRA acivity comprise thiker, fatter roots (a CORE or cobphenotype ) which are well suited for penetrating dense, compacted soil. Plants laking COBRA activity may be useful in applications wherein plant growth in areas with dense soil would be beneficial. The present invention comprises the Arobidopsis thaliana COBRA gene and COBRA protein and homologues thereof as well as mutated alleles of COBRA . Also provided are anti-COBRA antibodies, transgenic plants which overexpress COBRA and methods for identifying COBRA modulating substances.
摘要翻译：许多植物控制器官形状的方法是通过调节的差异细胞扩增。调节植物细胞扩增的基因，如拟南芥根系细胞是编码具有推定GPI锚的蛋白质的COBRA。包含改变的根形态的植物可以通过控制COBRA活性产生。例如，缺乏COBRA活性的根包括Thiker，较好的根（CORE或cobphenotype），它们非常适合穿透致密的，压实的土壤。剔除COBRA活性的植物可能适用于土壤密集区域植物生长有益的应用。本发明包括拟南芥COBRA基因和COBRA蛋白及其同源物，以及COBRA的突变等位基因。还提供了抗COBRA抗体，过表达COBRA的转基因植物和鉴定COBRA调节物质的方法。

2. 发明申请

WO1997041152A1 SCARECROW GENE, PROMOTER AND USES THEREOF 审中-公开
标题翻译： SCARECROW基因，促销者及其用途
公开(公告)号：WO1997041152A1
公开(公告)日：1997-11-06
申请号：PCT/US1997007022
申请日：1997-04-25
申请人： NEW YORK UNIVERSITY
发明人： NEW YORK UNIVERSITY , BENFEY, Philip, N. , DILAURENZIO, Laura , WYSOCKA-DILLER, Joanna , MALAMY, Jocelyn, E. , PYSH, Leonard , HELARIUTTA, Yrjo
IPC分类号： C07K14/415
CPC分类号： C12N15/8227 , C07K14/415 , C12N15/8222 , C12N15/8261 , Y02A40/146
摘要： The structure and function of a regulatory gene, SCARECROW (SCR), is described. The SCR gene is expressed specifically in root progenitor tissues of embryos, and in roots and stems of seedlings and plants. SCR expression controls cell division of certain cell types in roots and affects the organization of root tissues, and affects gravitropism of aerial structures. The invention relates to the SCARECROW (SCR) gene, SCR gene products, (including but not limited to transcriptional products such as mRNAs, antisense, and ribozyme molecules, and translational products such as the SCR protein, polypeptides, peptides and fusion proteins related thereto), antibodies to the SCR product, SCR promoters and regulatory regions and the use of the foregoing to improve agronomically valuable plants.
摘要翻译：描述了调节基因SCARECROW（SCR）的结构和功能。 SCR基因在胚胎的根祖细胞组织，以及幼苗和植物的根和茎中特异性表达。 SCR表达控制根中某些细胞类型的细胞分裂，并影响根组织的组织，并影响空中结构的引力。本发明涉及SCARECROW（SCR）基因，SCR基因产物（包括但不限于转录产物如mRNA，反义和核酶分子）和翻译产物如SCR蛋白，多肽，肽和与之相关的融合蛋白），SCR产物的抗体，SCR启动子和调节区以及上述用途以改善农学上有价值的植物。

3. 发明公开

EP0907660A1 SCARECROW GENE, PROMOTER AND USES THEREOF 失效
标题翻译：稻草人GEN谁的PRPMOTER及其用途
公开(公告)号：EP0907660A1
公开(公告)日：1999-04-14
申请号：EP97928623.0
申请日：1997-04-25
申请人： NEW YORK UNIVERSITY
发明人： BENFEY, Philip, N. , DILAURENZIO, Laura , WYSOCKA-DILLER, Joanna , MALAMY, Jocelyn, E. , PYSH, Leonard , HELARIUTTA, Yrjo
IPC分类号： C07K14 , C12N1 , C12N15
CPC分类号： C12N15/8227 , C07K14/415 , C12N15/8222 , C12N15/8261 , Y02A40/146
摘要： The structure and function of a regulatory gene, SCARECROW (SCR), is described. The SCR gene is expressed specifically in root progenitor tissues of embryos, and in roots and stems of seedlings and plants. SCR expression controls cell division of certain cell types in roots and affects the organization of root and stem tissues, and affects gravitropism of aerial structures. The invention relates to the SCARECROW (SCR) gene, SCR gene products, (including but not limited to transcriptional products such as mRNAs, antisense, and ribozyme molecules, and translational products such the SCR protein, polypeptides, peptides and fusion proteins related thereto), antibodies to SCR gene products, SCR promoters and regulatory regions and the use of the foregoing to improve agronomically valuable plants.

4. 发明公开

EP1290142A1 SHORT-ROOT GENE, PROMOTER, AND USES THEREOF 审中-公开
标题翻译： KURZWURZELGEN，推动者和用途
公开(公告)号：EP1290142A1
公开(公告)日：2003-03-12
申请号：EP01939595.3
申请日：2001-05-24
申请人： NEW YORK UNIVERSITY
发明人： BENFEY, Philip, N. , HELARIUTTA, Yrjo , FUKAKI, Hidehiro , NAKAJIMA, Keiji
IPC分类号： C12N5/04 , C12N5/10 , C12N15/00 , C12N15/09 , C12N15/63 , C12N15/70 , C12N15/74 , C12N15/82 , C12N15/87 , C07H21/04 , A01H1/00 , A01H5/00
CPC分类号： C12N15/8261 , C07K14/415 , C12N15/8227 , C12N15/8234 , Y02A40/146
摘要： The structure and function of a regulatory gene, SHORT-ROOT (SHR), is described. The SHR gene is expressed specifically in root progenitor tissues of embryos, and in roots and stems of seedlings and plants. SHR expression controls cell division of certain cell types in roots and affects the organization of root and stem tissues, and affects gravitropism of aerial structures. The invention relates to the SHR gene, SHR-like genes, SHR gene products, (including but not limited to transcriptional products such as mRNAs, antisense, and ribozyme molecules, and translational products such the SHR protein, polypeptides, peptides and fusion proteins related thereto), antibodies to SHR gene products, SHR promoters and regulatory regions and the use of the foregoing to improve agronomically valuable plants.

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