专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明申请

WO2006033971A2 STARCH-POMEGRANATE JUICE COOMPLEX AS AN HIV ENTRY INHIBITOR AND TOPICAL MICROBICIDE 审中-公开
标题翻译： STARCH-POMEGRANATE JUICE COOMPLEX作为HIV入侵抑制剂和局部杀微生物剂
公开(公告)号：WO2006033971A2
公开(公告)日：2006-03-30
申请号：PCT/US2005032979
申请日：2005-09-15
申请人： NEW YORK BLOOD CT INC , NEURATH ALEXANDER ROBERT , STRICK NATHAN , LI YUN-YAO
发明人： NEURATH ALEXANDER ROBERT , STRICK NATHAN , LI YUN-YAO
IPC分类号： A01N65/08 , A61K36/185
CPC分类号： A61K36/185 , A61K9/0031 , A61K9/0034
摘要： A complex comprising a starch and an active antiHIV-1 or anti-HIV-2 ingredient of pomegranate juice that is adsorbed on the starch when the starch is in a water insoluble form. The complex inhibits HIV-1 or HIV-2 infection and blocks the binding of HIV-1 or HIV-2 to the CD4 receptor and the CCR5 and CXCR4 coreceptors. The complex is used in a method of preventing HIV-1 or HIV-2 infection comprising administering to a mucous membrane of a human a pharmaceutically effective anti-HIV-1 or anti-HIV-2 amount of the complex.
摘要翻译：包含淀粉和石榴汁的活性抗HIV-1或抗HIV-2成分的复合物，当淀粉为水不溶形式时，其被吸附在淀粉上。该复合物抑制HIV-1或HIV-2感染并阻断HIV-1或HIV-2与CD4受体和CCR5和CXCR4共同受体的结合。该复合物用于预防HIV-1或HIV-2感染的方法中，包括向人的粘膜施用药学上有效的抗HIV-1或抗HIV-2量的复合物。

2. 发明申请

WO2007044348A3 ANTI-INFECTIVE HYGIENE PRODUCTS BASED ON CELLULOSE ACETATE PHTHALATE 审中-公开
标题翻译：基于纤维素乙酸邻苯二甲酸酯的抗感染卫生产品
公开(公告)号：WO2007044348A3
公开(公告)日：2007-11-22
申请号：PCT/US2006038668
申请日：2006-10-04
申请人： NEW YORK BLOOD CT INC , NEURATH ALEXANDER ROBERT , STRICK NATHAN , LI YUN-YAO
发明人： NEURATH ALEXANDER ROBERT , STRICK NATHAN , LI YUN-YAO
IPC分类号： A61F13/02 , A61F13/20
CPC分类号： A61F13/2051 , A61K31/717
摘要： Methods for maintaining a low vaginal pH, preventing the propagation of toxic shock syndrome toxin (1) production during menstruation, preventing the shedding and dissemination of a herpesvirus and treating herpes lesions comprising administering to a human a formulation comprising a pharmaceutically effective amount of an insoluble micronized form of cellulose acetate phthalate or a cellulose acetate phthalate film or a cellulose acetate phthalate porous sponge. Also a method of treating Candida albicans infection comprising.administering to a human female a pharmaceutically effective amount of a composition comprising micronized cellulose acetate phthalate and miconazole nitrate.
摘要翻译：用于维持低阴道pH值，防止月经期间中毒性休克综合征毒素（1）产生的增加，防止疱疹病毒脱落和散播以及治疗疱疹病变的方法，包括向人施用包含药学有效量的不溶性微粉化形式的醋酸邻苯二甲酸纤维素或醋酸邻苯二甲酸纤维素膜或邻苯二甲酸醋酸纤维素多孔海绵。治疗白色念珠菌感染的方法还包括给予人类女性一种药用有效量的包含微粉化醋酸邻苯二甲酸纤维素和硝酸咪康唑的组合物。

3. 发明申请

WO2007044348A8 ANTI-INFECTIVE HYGIENE PRODUCTS BASED ON CELLULOSE ACETATE PHTHALATE 审中-公开
标题翻译：基于纤维素乙酸酯类抗生素的抗感染性卫生产品
公开(公告)号：WO2007044348A8
公开(公告)日：2007-06-14
申请号：PCT/US2006038668
申请日：2006-10-04
申请人： NEW YORK BLOOD CT INC , NEURATH ALEXANDER ROBERT , STRICK NATHAN , LI YUN-YAO
发明人： NEURATH ALEXANDER ROBERT , STRICK NATHAN , LI YUN-YAO
IPC分类号： A61K31/717 , A61F13/20
CPC分类号： A61F13/2051 , A61K31/717
摘要： Methods for maintaining a low vaginal pH, preventing the propagation of toxic shock syndrome toxin (1) production during menstruation, preventing the shedding and dissemination of a herpesvirus and treating herpes lesions comprising administering to a human a formulation comprising a pharmaceutically effective amount of an insoluble micronized form of cellulose acetate phthalate or a cellulose acetate phthalate film or a cellulose acetate phthalate porous sponge. Also a method of treating Candida albicans infection comprising.administering to a human female a pharmaceutically effective amount of a composition comprising micronized cellulose acetate phthalate and miconazole nitrate.
摘要翻译：维持低阴道pH值的方法，防止在月经期间产生毒性休克综合征毒素（1）的繁殖，防止疱疹病毒的脱落和传播并治疗疱疹病变，其包括向人施用包含药物有效量的不溶性醋酸纤维素邻苯二甲酸酯或醋酸纤维素邻苯二甲酸酯薄膜或醋酸纤维素邻苯二甲酸盐多孔海绵的微粉化形式。还包括治疗白念珠菌感染的方法，其包括向人类女性提供药学有效量的包含微粉化的邻苯二甲酸纤维素和硝酸咪康唑的组合物。

4. 发明申请

WO2005034854A3 WATER DISPERSIBLE FILM 审中-公开
标题翻译：水分散膜
公开(公告)号：WO2005034854A3
公开(公告)日：2005-06-09
申请号：PCT/US2004028178
申请日：2004-08-30
申请人： NEW YORK BLOOD CT INC , NEURATH ALEXANDER ROBERT , STRICK NATHAN , LI YUN-YAO
发明人： NEURATH ALEXANDER ROBERT , STRICK NATHAN , LI YUN-YAO
IPC分类号： A61K9/00 , A61K9/70 , A61K31/716 , A61F13/00
CPC分类号： A61K31/716 , A61K9/0034 , A61K9/7007
摘要： A soft, pliable cellulose acetate phthalate (CAP) - hydroxypropyl cellulose (HPC) composite film is provided which is generated by casting from organic solvent mixtures containing ethanol. The film rapidly reduces the infectivity of several sexually transmitted disease pathogens, including the human immunodeficiency virus (HIV-1), herpesvirus (HSV), non-viral sexually transmitted disease pathogens (such as Neisseria gonorrhoeae, Haemophilus ducreyi, Chlamydia trachomatis and Treponema pallidum) and bacteria associated with bacterial vaginosis (BV). The film is converted into a gel/cream and thus does not have to be removed following application and use. In addition to being a topical microbicide, the film can be employed for the mucosal delivery of pharmaceuticals other than cellulose acetate phthalate.
摘要翻译：提供柔软的，柔韧的乙酸邻苯二甲酸纤维素（CAP） - 羟丙基纤维素（HPC）复合膜，其通过从含有乙醇的有机溶剂混合物中浇铸而产生。该片迅速降低了几种性传播疾病病原体的感染性，包括人类免疫缺陷病毒（HIV-1），疱疹病毒（HSV），非病毒性传播疾病病原体（如淋病奈瑟氏球菌，杜氏血吸虫，沙眼衣原体和苍白密螺旋体）和细菌性阴道炎相关的细菌（BV）。该胶片被转化为凝胶/霜剂，因此在使用和使用后不需要除去。除了是局部杀微生物剂之外，该膜还可用于除了邻苯二甲酸乙酸纤维素之外的药物的粘膜递送。

5. 发明公开

EP1030547A4 METHODS FOR PREVENTING AND TREATING BACTERIAL INFECTIONS USING CELLULOSE ACETATE PHTHALATE OR HYDROXYPROPYL METHYLCELLULOSE PHTHALATE EXCIPIENTS 有权
标题翻译：方法预防和治疗中使用或CELLULOSEACETATPHTHALAT-HYDROXYPROPPYLMETHYLCELLULOSETRÄGERSTOFFEN细菌感染
公开(公告)号：EP1030547A4
公开(公告)日：2002-11-06
申请号：EP98956122
申请日：1998-10-21
申请人： NEW YORK BLOOD CT INC , NEURATH ALEXANDER ROBERT , JIANG SHIBO , DEBNATH ASIM KUMAR , STRICK NATHAN , DOW GORDON J
发明人： NEURATH ALEXANDER ROBERT , JIANG SHIBO , DEBNATH ASIM KUMAR , STRICK NATHAN , DOW GORDON JAY
IPC分类号： A61K9/06 , A61K9/107 , A61K9/14 , A61K31/717 , A61K47/02 , A61K47/10 , A61K47/32 , A61P31/04 , A61P31/12 , A61P31/18 , A61P31/22 , A01F25/02 , A01F25/08 , A61K31/715
CPC分类号： A61K9/14 , A61K31/717

6. 发明申请

WO2008148018A2 RAPIDLY DISPERSIBLE VAGINAL TABLET THAT PROVIDES A BIOADHESIVE GEL 审中-公开
标题翻译：提供生物凝胶的快速不平的血管片
公开(公告)号：WO2008148018A2
公开(公告)日：2008-12-04
申请号：PCT/US2008064737
申请日：2008-05-23
申请人： NEW YORK BLOOD CT INC , STONE ALAN , NEURATH ALEXANDER ROBERT , STRICK NATHAN , JIANG SHIBO
发明人： STONE ALAN , NEURATH ALEXANDER ROBERT , STRICK NATHAN , JIANG SHIBO
IPC分类号： A61K9/20
CPC分类号： A61K9/0034 , A61K9/2018 , A61K31/00
摘要： A tablet for insertion into a vagina including 0.01 to 500 mg of a vaginal medication, such as a microbicide, such as cellulose acetate 1,2- benzenedicarboxylate (CAP); 100 to 500 mg of mannitol powder; 50 to 300 mg of inert microcrystalline cellulose; 10 to 80 mg of hydroxypropyl methylcellulose; 50 to 250 mg of glycerol and optionally 2 to 4 mg of at least one preservative which protects against microbicidal contamination and discourages the growth of yeast in the vagina. The tablet which includes CAP as the vaginal medication is vaginally administered before coitus in methods for preventing the sexual transmission of HIV- 1, HIV-2, herpesvirus, or an infection caused by Neisseria gonorrhoeae, Chlamydia trachomatis, Trichomonas vaginalis, Haemophilus ducreyi or Treponema pallidum. The tablet which includes CAP as the vaginal medication is vaginally administered to prevent or treat bacterial vaginosis.
摘要翻译：用于插入阴道的片剂，其包含0.01至500mg的阴道药物，例如杀微生物剂，例如1,2-乙二羧酸纤维素酯（CAP）; 100〜500mg甘露糖醇粉末; 50〜300mg惰性微晶纤维素; 10至80mg羟丙基甲基纤维素; 50至250mg的甘油和任选的2至4mg的至少一种防腐剂，其防止杀微生物污染并阻止酵母在阴道中的生长。包括CAP作为阴道药物的片剂在防止HIV-1，HIV-2，疱疹病毒的性传播或由淋病奈瑟氏球菌，沙眼衣原体，阴道毛滴虫，杜氏乳杆菌或密螺旋体感染引起的感染的方法之前阴道给药梅毒螺旋体。包括CAP作为阴道药物的片剂被阴道施用以预防或治疗细菌性阴道病。

7. 发明专利

DE69828196T2 未知
公开(公告)号：DE69828196T2
公开(公告)日：2006-02-23
申请号：DE69828196
申请日：1998-10-21
申请人： NEW YORK BLOOD CT INC , NEURATH ALEXANDER ROBERT , JIANG SHIBO , DEBNATH ASIM KUMAR , STRICK NATHAN , DOW GORDON J
发明人： NEURATH ROBERT , JIANG SHIBO , DEBNATH KUMAR , STRICK NATHAN , DOW JAY
IPC分类号： A61K9/06 , A61K9/107 , A61K9/14 , A61K31/715 , A61K31/717 , A61K47/02 , A61K47/10 , A61K47/32 , A61P31/04 , A61P31/12 , A61P31/18 , A61P31/22
摘要： A method for decreasing the frequency of transmission of human immunodeficiency virus or herpesviruses or for preventing the transmission of or treating a sexually transmitted bacterial infection by administering to a human an anti-human immunodeficiency virus amount or an anti-herpesvirus amount or an anti-bacterial amount of cellulose acetate phthalate (CAP) or hydroxypropyl methylcellulose phthalate (HPMCP), such as in micronized form, or a combination thereof, either alone or in combination with a pharmaceutically acceptable carrier or diluent. The CAP and/or HPMCP may be employed as a suspension of micronized particles and may further contain a water miscible, non-solvent for CAP or HPMCP, such as glycerol.

8. 发明专利

AT284675T 未知
公开(公告)号：AT284675T
公开(公告)日：2005-01-15
申请号：AT98956122
申请日：1998-10-21
申请人： NEW YORK BLOOD CT INC , NEURATH ALEXANDER ROBERT , JIANG SHIBO , DEBNATH ASIM KUMAR , STRICK NATHAN , DOW GORDON J
发明人： NEURATH ALEXANDER ROBERT , JIANG SHIBO , DEBNATH ASIM KUMAR , STRICK NATHAN , DOW GORDON JAY
IPC分类号： A61K9/06 , A61K9/107 , A61K9/14 , A61K31/717 , A61K47/02 , A61K47/10 , A61K47/32 , A61P31/04 , A61P31/12 , A61P31/18 , A61P31/22 , A61K31/715
摘要： A method for decreasing the frequency of transmission of human immunodeficiency virus or herpesviruses or for preventing the transmission of or treating a sexually transmitted bacterial infection by administering to a human an anti-human immunodeficiency virus amount or an anti-herpesvirus amount or an anti-bacterial amount of cellulose acetate phthalate (CAP) or hydroxypropyl methylcellulose phthalate (HPMCP), such as in micronized form, or a combination thereof, either alone or in combination with a pharmaceutically acceptable carrier or diluent. The CAP and/or HPMCP may be employed as a suspension of micronized particles and may further contain a water miscible, non-solvent for CAP or HPMCP, such as glycerol.

9. 发明专利

DE69828196D1 未知
公开(公告)号：DE69828196D1
公开(公告)日：2005-01-20
申请号：DE69828196
申请日：1998-10-21
申请人： NEW YORK BLOOD CT INC , NEURATH ALEXANDER ROBERT , JIANG SHIBO , DEBNATH ASIM KUMAR , STRICK NATHAN , DOW GORDON J
发明人： NEURATH ROBERT , JIANG SHIBO , DEBNATH KUMAR , STRICK NATHAN , DOW JAY
IPC分类号： A61K9/06 , A61K9/107 , A61K9/14 , A61K31/717 , A61K47/02 , A61K47/10 , A61K47/32 , A61P31/04 , A61P31/12 , A61P31/18 , A61P31/22 , A61K31/715
摘要： A method for decreasing the frequency of transmission of human immunodeficiency virus or herpesviruses or for preventing the transmission of or treating a sexually transmitted bacterial infection by administering to a human an anti-human immunodeficiency virus amount or an anti-herpesvirus amount or an anti-bacterial amount of cellulose acetate phthalate (CAP) or hydroxypropyl methylcellulose phthalate (HPMCP), such as in micronized form, or a combination thereof, either alone or in combination with a pharmaceutically acceptable carrier or diluent. The CAP and/or HPMCP may be employed as a suspension of micronized particles and may further contain a water miscible, non-solvent for CAP or HPMCP, such as glycerol.

10. 发明专利

AU1157902A Biodegradable microbicidal vaginal barrier device 未知
公开(公告)号：AU1157902A
公开(公告)日：2002-05-15
申请号：AU1157902
申请日：2001-10-10
申请人： NEW YORK BLOOD CT INC , NEURATH ALEXANDER ROBERT , STRICK NATHAN
发明人： NEURATH ALEXANDER ROBERT , STRICK NATHAN
IPC分类号： A61K9/00 , A61K9/12 , A61P31/12 , A61P31/18 , A61F13/15
摘要： An intravaginal bio-erodible microbicidal barrier device. The device comprises (a) at least one micronized compound selected from the group consisting of cellulose acetate phthalate and hydroxypropylmethylcellulose phthalate, and (b) at least one water soluble or water dispersible cellulose compound selected from the group consisting of hydroxypropylmethylcellulose, methylcellulose, hydroxyethylcellulose, hydroxypropylcellulose, hydroxyethylmethylcellulose, hydroxyethylethylcellulose and hydroxypropylethylcellulose. The device is prepared by a combination of foaming, freezing and freeze-drying processes.

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式