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1. 发明申请

WO2014177667A1 LACHNOSPIRACEAE IN THE GUT MICROBIOTA AND ASSOCIATION WITH BODY WEIGHT 审中-公开
标题翻译：乳腺微生物中的LACHNOSPIRACEAE和身体重量的关联
公开(公告)号：WO2014177667A1
公开(公告)日：2014-11-06
申请号：PCT/EP2014/058942
申请日：2014-05-01
申请人： NESTEC S.A.
发明人： DARIMONT-NICOLAU, Christian , BERGER, Bernard , REZZONICO, Enea , NGOM-BRU, Catherine , LEPAGE, Melissa
IPC分类号： A61K35/74 , G01N33/50 , A61P3/04 , A61K8/99
CPC分类号： A61K35/747 , A23L33/135 , A23V2002/00 , A23Y2220/73 , A61K8/99 , A61K2800/92 , A61Q19/06 , C12Q1/04 , C12Q1/06 , G01N2333/33 , G01N2800/044 , A23V2200/3204 , A23V2200/332
摘要： The present invention relates to means and methods for modulating the gut microbiota composition of a subject, preferably a human. In particular, the present invention provides an agent capable of reducing the proportion of Lachnospiraceae in the gut microbiota composition of a subject which agent is useful for promoting weight loss or preventing weight gain in a subject, preferably an obese or overweight subject. Lactobacillus rhamnosus CGMCC 1.3724 is particularly preferred as the agent provided by and used in the present invention.
摘要翻译：本发明涉及用于调节受试者，优选人的肠道微生物群组成的方法和方法。特别地，本发明提供一种能够减少受试者的肠道微生物群组合物中Lachnospiraceae的比例的试剂，该试剂可用于促进体重减轻或预防受试者，优选肥胖或超重受试者的体重增加。作为由本发明提供并用于本发明的试剂，特别优选鼠李糖乳杆菌CGMCC 1.3724。

2. 发明申请

WO2017198652A3 FLAVOUR GENERATION IN FOOD 审中-公开
公开(公告)号：WO2017198652A3
公开(公告)日：2017-11-23
申请号：PCT/EP2017/061702
申请日：2017-05-16
申请人： NESTEC S.A.
发明人： FLEURY REY, Yvette , VAFEIADI, Christina , DUBOUX, Stéphane , NGOM-BRU, Catherine , TASTET, Clémentine , MOKDAD, Cassandra , GYSLER, Christof , HANSEN, Carl Erik
IPC分类号： C12N9/52 , A23L5/20 , A21D8/04
摘要： The present invention relates to flavour generation. In particular the invention relates to a method for flavour generation in aheat-treatedfood productusing a prolidase enzyme. The invention also relates to a heat-treated food product prepared according to the method of the invention.

3. 发明申请

WO2016066763A1 USE OF L. REUTERI FOR RECOVERY OF MICROBIOTA DYSBIOSIS IN EARLY LIFE 审中-公开
标题翻译：微生物在早期生活中恢复微生物的应用
公开(公告)号：WO2016066763A1
公开(公告)日：2016-05-06
申请号：PCT/EP2015/075164
申请日：2015-10-29
申请人： NESTEC S.A.
发明人： GARCIA-RODENAS, Clara Lucia , BERGER, Bernard , NGOM-BRU, Catherine , LEPAGE, Melissa , NEVILLE, Tara
IPC分类号： A61K35/747 , A61K35/745 , A61K31/702 , A61P1/00 , A61P3/04 , A61P3/10
CPC分类号： A61K35/747 , A23L33/135 , A23L33/40 , A23Y2220/71 , A61K31/702 , A61K31/733 , A61K35/745 , A61K45/06 , A61K2300/00
摘要： The invention concerns Lactobacillus reuteri for use in the prevention or treatment of microbiota dysbiosis, in particular, decreased levels of Actinobacteria and increased levels of Proteobacteria, in young mammals and in the prevention or treatment of disorders associated therewith. The microbiota dysbiosis may have been cause by numerous factors including being born by caesarean section, exposure to antibiotics in utero or after birth, or, parenteral feeding, hospitalizing, psychological stress or by gastrointestinal dysfunctions. The disorders that may be treated or prevented by preventing or treating microbiota dysbiosis include propensity to infection, allergy, type I diabetes mellitus, insulin resistance, type 2 diabetes, celiac disease, peripheral and central adiposity, obesity, necrotizing enterocolitis, inflammatory bowel disease, such as Crohn's disease and ulcerative colitis, and functional gastrointestinal disorders such as IBS, functional diarrhea, functional constipation, recurrent abdominal pain, and dyspepsia.
摘要翻译：本发明涉及用于预防或治疗微生物群发育不良的罗拉伊氏乳杆菌（Lactobacillus reuteri），特别是在年轻哺乳动物中降低的放线菌素水平和变形杆菌水平的增加以及与之相关的病症的预防或治疗。微生物群发育不良可能是由许多因素造成的，包括剖宫产，子宫内或出生后暴露于抗生素，肠胃外给药，住院，心理压力或胃肠功能障碍。可能通过预防或治疗微生物群发育不良症而被治疗或预防的疾病包括感染倾向，过敏，I型糖尿病，胰岛素抵抗，2型糖尿病，腹腔疾病，外周和中枢性肥胖，肥胖，坏死性小肠结肠炎，炎性肠病，例如克罗恩病和溃疡性结肠炎，以及功能性胃肠疾病如IBS，功能性腹泻，功能性便秘，复发性腹痛和消化不良。

4. 发明申请

WO2017198652A2 FLAVOUR GENERATION IN FOOD 审中-公开
标题翻译：食物中的味道
公开(公告)号：WO2017198652A2
公开(公告)日：2017-11-23
申请号：PCT/EP2017/061702
申请日：2017-05-16
申请人： NESTEC S.A.
发明人： FLEURY REY, Yvette , VAFEIADI, Christina , DUBOUX, Stéphane , NGOM-BRU, Catherine , TASTET, Clémentine , MOKDAD, Cassandra , GYSLER, Christof , HANSEN, Carl Erik
IPC分类号： C12N9/52
摘要： The present invention relates to flavour generation. In particular the invention relates to a method for flavour generation in aheat-treatedfood productusing a prolidase enzyme. The invention also relates to a heat-treated food product prepared according to the method of the invention.
摘要翻译：本发明涉及香味产生。具体地说，本发明涉及一种使用氨酰基脯氨酸酶在厌氧处理过的食品中产生香味的方法。本发明还涉及根据本发明方法制备的热处理食品。

5. 发明申请

WO2017198650A1 FLAVOUR GENERATION IN FOOD 审中-公开
标题翻译：食物中的味道
公开(公告)号：WO2017198650A1
公开(公告)日：2017-11-23
申请号：PCT/EP2017/061698
申请日：2017-05-16
申请人： NESTEC S.A.
发明人： FLEURY REY, Yvette , VAFEIADI, Christina , DUBOUX, Stéphane , NGOM-BRU, Catherine , MOKDAD, Cassandra , TASTET, Clémentine , GYSLER, Christof , HANSEN, Carl Erik
IPC分类号： A23L5/20 , A21D8/04 , C12N9/52
摘要： The present invention relates to flavour generation. In particular the invention relates to a method for flavour generation in a heat-treated food product using a prolidase enzyme. The invention also relates to a heat-treated food product prepared according to the method of the invention.
摘要翻译：本发明涉及香味产生。具体地说，本发明涉及使用氨酰基脯氨酸酶在经热处理的食品中产生香味的方法。本发明还涉及根据本发明方法制备的热处理食品。

6. 发明授权

EP2991659B1 LACHNOSPIRACEAE IN THE GUT MICROBIOTA AND ASSOCIATION WITH BODY WEIGHT 有权转让
公开(公告)号：EP2991659B1
公开(公告)日：2018-10-10
申请号：EP14721360.7
申请日：2014-05-01
申请人： Nestec S.A.
发明人： DARIMONT-NICOLAU, Christian , BERGER, Bernard , REZZONICO, Enea , NGOM-BRU, Catherine , LEPAGE, Melissa
IPC分类号： A61K35/747 , G01N33/50 , A61P3/04 , A61K8/99 , C12Q1/04 , A23L33/135 , A61Q19/06
CPC分类号： A61K35/747 , A23L33/135 , A23V2002/00 , A23Y2220/73 , A61K8/99 , A61K2800/92 , A61Q19/06 , C12Q1/04 , C12Q1/06 , G01N2333/33 , G01N2800/044 , A23V2200/3204 , A23V2200/332
摘要： The present invention relates to means and methods for modulating the gut microbiota composition of a subject, preferably a human. In particular, the present invention provides an agent capable of reducing the proportion of Lachnospiraceae in the gut microbiota composition of a subject which agent is useful for promoting weight loss or preventing weight gain in a subject, preferably an obese or overweight subject. Lactobacillus rhamnosus CGMCC 1.3724 is particularly preferred as the agent provided by and used in the present invention.

7. 发明公开

EP2991659A1 LACHNOSPIRACEAE IN THE GUT MICROBIOTA AND ASSOCIATION WITH BODY WEIGHT 有权转让
标题翻译：毛螺INDARMBIOZÖNOSE并与主体权重联系
公开(公告)号：EP2991659A1
公开(公告)日：2016-03-09
申请号：EP14721360.7
申请日：2014-05-01
申请人： Nestec S.A.
发明人： DARIMONT-NICOLAU, Christian , BERGER, Bernard , REZZONICO, Enea , NGOM-BRU, Catherine , LEPAGE, Melissa
IPC分类号： A61K35/74 , G01N33/50 , A61P3/04 , A61K8/99
CPC分类号： A61K35/747 , A23L33/135 , A23V2002/00 , A23Y2220/73 , A61K8/99 , A61K2800/92 , A61Q19/06 , C12Q1/04 , C12Q1/06 , G01N2333/33 , G01N2800/044 , A23V2200/3204 , A23V2200/332
摘要： The present invention relates to means and methods for modulating the gut microbiota composition of a subject, preferably a human. In particular, the present invention provides an agent capable of reducing the proportion of Lachnospiraceae in the gut microbiota composition of a subject which agent is useful for promoting weight loss or preventing weight gain in a subject, preferably an obese or overweight subject. Lactobacillus rhamnosus CGMCC 1.3724 is particularly preferred as the agent provided by and used in the present invention.

8. 发明公开

EP3458582A2 FLAVOUR GENERATION IN FOOD 审中-实审转让
公开(公告)号：EP3458582A2
公开(公告)日：2019-03-27
申请号：EP17729379.2
申请日：2017-05-16
申请人： Nestec S.A.
发明人： FLEURY REY, Yvette , VAFEIADI, Christina , DUBOUX, Stéphane , NGOM-BRU, Catherine , TASTET, Clémentine , MOKDAD, Cassandra , GYSLER, Christof , HANSEN, Carl Erik
IPC分类号： C12N9/52 , A23L5/20 , A21D8/04

9. 发明公开

EP3457868A1 FLAVOUR GENERATION IN FOOD 审中-实审转让
公开(公告)号：EP3457868A1
公开(公告)日：2019-03-27
申请号：EP17723408.5
申请日：2017-05-16
申请人： Nestec S.A.
发明人： FLEURY REY, Yvette , VAFEIADI, Christina , DUBOUX, Stéphane , NGOM-BRU, Catherine , MOKDAD, Cassandra , TASTET, Clémentine , GYSLER, Christof , HANSEN, Carl Erik
IPC分类号： A23L5/20 , A21D8/04 , C12N9/52

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