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1. 发明申请

WO2006121447A3 THERAPEUTIC ASSEMBLY 审中-公开
公开(公告)号：WO2006121447A3
公开(公告)日：2006-11-16
申请号：PCT/US2005/020109
申请日：2005-06-08
申请人： NANOSET, LLC , WANG, Xingwu , GREENWALD, Howard, J. , LANZAFAME, John , WEINER, Michael, L. , CONNELLY, Patrick, R.
发明人： WANG, Xingwu , GREENWALD, Howard, J. , LANZAFAME, John , WEINER, Michael, L. , CONNELLY, Patrick, R.
IPC分类号： A61N5/00
摘要： A therapeutic assembly that contains a therapeutic agent, a cytotoxic radioactive material, and a nanomagnetic material with nanomagnetic particles. The nanomagnetic particles have an average particle size of less than about 100 nanometers; and the average coherence length between adjacent nanomagnetic particles is less than 100 nanometers. The nanomagnetic material has a saturation magnetization of from about 2 to about 3000 electromagnetic units per cubic centimeter, a phase transition temperature of from about 40 to about 200 degrees Celsius, and a saturation magnetization of from about 2 to about 3,000 electromagnetic units per cubic centimeter.

2. 发明申请

WO2006083796A2 NOVEL COMPOSITION 审中-公开
标题翻译：新构成
公开(公告)号：WO2006083796A2
公开(公告)日：2006-08-10
申请号：PCT/US2006/003294
申请日：2006-01-30
申请人： NANOSET, LLC , WANG, Xingwu , GREENWALD, Howard, J. , WEINER, Michael, L.
发明人： WANG, Xingwu , GREENWALD, Howard, J. , WEINER, Michael, L.
IPC分类号： H01F1/00
CPC分类号： B82Y25/00 , A61K47/6957 , A61L27/446 , A61L27/50 , A61M25/0045 , A61M25/1027 , A61M2025/1088 , H01F1/0063
摘要： A nancomposite material containing nanomagnetic material disposed within a matrix. The nanomagnetic material has a saturation magentization of from about 2 to about 3000 electromagnetic units per cubic centimeter and contains nanomagnetic particles with an average particle size of less than about 100 nanometers; the average coherence length between adjacent nanomagnetic particles is less than 100 nanometers.
摘要翻译：纳米复合材料，其包含设置在基体内的纳米磁性材料。纳米磁性材料具有约2至约3000个电磁单位/立方厘米的饱和磁化，并且包含平均粒度小于约100纳米的纳米磁性颗粒; 相邻纳米磁性颗粒之间的平均相干长度小于100纳米。

3. 发明申请

WO2005110217A1 MAGNETIC RESONANCE IMAGING COATED ASSEMBLY 审中-公开
标题翻译：磁共振成像涂层组件
公开(公告)号：WO2005110217A1
公开(公告)日：2005-11-24
申请号：PCT/US2005/013020
申请日：2005-04-19
申请人： NANOSET, LLC , WANG, Xingwu , GREENWALD, Howard, J. , HELFER, Jeffrey, L. , GRAY, Robert, W. , WEINER, Michael, L.
发明人： WANG, Xingwu , GREENWALD, Howard, J. , HELFER, Jeffrey, L. , GRAY, Robert, W. , WEINER, Michael, L.
IPC分类号： A61B5/05
CPC分类号： G01R33/286 , A61K49/1818 , A61N1/16 , B82Y5/00 , B82Y25/00 , H01B11/10 , H01B11/1083 , H01F10/007 , H01F10/324
摘要： An assembly for shielding an implanted medical device form the effects of high-frequency radiation and for emitting magnetic resonance signals during magnetic resonance imaging. The assembly includes an implanted medical device and a magnetic shield comprised of nanomagnetic material disposed between the medical device and the high-frequency radiation. In one embodiment, the magnetic resonance signals are detected by a receiver, which is thus able to located the implanted medical device within a biological organism.
摘要翻译：用于屏蔽植入的医疗装置的组件形成高频辐射的影响并且用于在磁共振成像期间发射磁共振信号。该组件包括植入医疗装置和由设置在医疗装置与高频辐射之间的纳米磁性材料构成的磁屏蔽。在一个实施例中，磁共振信号由接收器检测，接收器因此能够将植入的医疗装置定位在生物体内。

4. 发明申请

WO2006127474A2 MEDICAL DEVICE 审中-公开
标题翻译：医疗装置
公开(公告)号：WO2006127474A2
公开(公告)日：2006-11-30
申请号：PCT/US2006/019482
申请日：2006-05-19
申请人： NANOSET, LLC , WANG, Xingwu , GREENWALD, Howard, J.
发明人： WANG, Xingwu , GREENWALD, Howard, J.
IPC分类号： A61F2/06
CPC分类号： A61F2/82
摘要： An implantable medical device comprised of a lumen with a volume of from about 1 x 10 -7 cubic meters to 1 x 10 -5 cubic meters wherein, when said device is exposed to radio frequency electromagnetic radiation with a frequency of from 10 megahertz to about 200 megahertz, at least 90 percent of the electromagnetic radiation penetrates to the lumen of the device, and the concentration of the electromagnetic radiation that penetrates to the lumen of the device is substantially identical at different points within such lumen. When the device is, at different points in time, exposed to two different radio frequency electromagnetic radiations, one of whose frequencies differs from the other by a factor of at least 1.5, at least 90 percent of each of the radio frequency electromagnetic radiations penetrates to the lumen of the device.
摘要翻译：一种可植入医疗装置，其包括体积为约1×10 -7立方米至1×10 -5立方米的内腔，其中当所述装置暴露时对于频率为10兆赫兹至约200兆赫兹的射频电磁辐射，至少90％的电磁辐射渗透到该装置的内腔，并且穿透该装置的内腔的电磁辐射的浓度基本上在这样的管腔内的不同点相同。当设备在不同的时间点暴露于两个不同的射频电磁辐射时，其中一个频率与另一个的频率不同，至少为1.5倍，每个射频电磁辐射的至少90％渗透到设备的管腔。

5. 发明申请

WO2006116538A2 MEDICAL DEVICE WITH A MARKER 审中-公开
标题翻译：具有标记的医疗设备
公开(公告)号：WO2006116538A2
公开(公告)日：2006-11-02
申请号：PCT/US2006/015897
申请日：2006-04-26
申请人： NANOSET, LLC , WANG, Xingwu , GREENWALD, Howard, J.
发明人： WANG, Xingwu , GREENWALD, Howard, J.
IPC分类号： A61K49/00 , C07F5/00
CPC分类号： A61K49/18 , A61K49/1818
摘要： A contrast-enhancing agent that has a saturation magnetization of at least 1.5 Tesla and that, when contacted with MRI radiation, provides a first gray scale response that is substantially uniform and that has a resolution of at least about 1 millimeter. When the contrast-enhancing agent is repeatedly contacted with said MRI radiation over a period of at least one year, it will repeatedly produce gray scale responses which are substantially identical to the first gray scale response.
摘要翻译：具有至少1.5特斯拉的饱和磁化强度的对比度增强剂，并且当与MRI辐射接触时，提供基本均匀的并且具有至少约1毫米的分辨率的第一灰度响应。当对比度增强剂在至少一年的时间内与所述MRI辐射重复接触时，它将重复产生与第一灰度响应基本相同的灰度响应。

6. 发明申请

WO2006093804A3 COATED SUBSTRATE ASSEMBLY 审中-公开
公开(公告)号：WO2006093804A3
公开(公告)日：2006-09-08
申请号：PCT/US2006/006459
申请日：2006-02-24
申请人： NANOSET LLC , WANG, Xingwu , GREENWALD, Howard J.
发明人： WANG, Xingwu , GREENWALD, Howard J.
IPC分类号： A61B19/00 , A61N5/00
摘要： A coated assembly comprised of a coating that has a relative magnetic permeability of at least 1.1 over the range of frequencies of from about 10 megahertz to about 200 megahertz, an increase of such relative magnetic permeability over such range of from about 1 x 10-14 to about 1 x 10-6 per hertz, and a magnetization, when measured at a direct current magnetic field of 2 Tesla, of from about 0.1 to about 10 electromagnetic units per cubic centimeter.

7. 发明申请

WO2006014524A2 MEDICAL DEVICE WITH LOW MAGNETIC SUSCEPTIBILITY 审中-公开
标题翻译：具有低磁性不牢度的医疗装置
公开(公告)号：WO2006014524A2
公开(公告)日：2006-02-09
申请号：PCT/US2005/024056
申请日：2005-07-07
申请人： NANOSET, LLC , WANG, Xingwu , GREENWALD, Howard, J.
发明人： WANG, Xingwu , GREENWALD, Howard, J.
IPC分类号： A61K9/14
CPC分类号： A61F2/82 , A61F2/0077 , A61F2210/009 , A61F2250/0067 , A61L31/10 , A61L31/18
摘要： An assembly that contains a medical device and biological material within which the medical device is disposed. The assembly has a direct or alternating current magnetic susceptibility within the range of from about plus 1 x 10 -2 centimeter-gram-seconds to about minus 1 x 10 -2 centimeter-gram-seconds.
摘要翻译：包含医疗装置和医疗装置所在的生物材料的组件。该组件具有在大约±1×10 -2厘米 - 克 - 秒至约-1×10 -2厘米的范围内的直接或交流磁化率 -gram秒。

8. 发明申请

WO2003061755A3 NANOMAGNETICALLY SHIELDED SUBSTRATE 审中-公开
公开(公告)号：WO2003061755A3
公开(公告)日：2003-07-31
申请号：PCT/US2003/001671
申请日：2003-01-21
申请人： NANOSET, LLC , WANG, Xingwu , HELFER, Jeffrey, L. , MACDONALD, Stuart, G. , GREENWALD, Howard, J.
发明人： WANG, Xingwu , HELFER, Jeffrey, L. , MACDONALD, Stuart, G. , GREENWALD, Howard, J.
IPC分类号： H01B11/06
摘要： A shielded substrate assembly that contains a magnetic shield with a layer of magnetic shielding material (24); the magnetic shield has a magnetic shielding factor of at least about 0.5. The magnetic shield contains nanomagnetic material with a mass density of at least about 0.01 grams per cubic centimeter, a saturation magnetization of from about 1 to about 36,000 Gauss, a coercive force of from about 0.01 to about 5,000 Oersteds, a relative magnetic permeability of from about 1 to about 500,000, and an average particle size of less than about 100 nanometers. In one embodiment, the nanomagnetic material contains magnetic material with a coherence length of from about 0.1 to about 100 nanometers.

9. 发明申请

WO2007089230A2 NOVEL COMPOSITION 审中-公开
标题翻译：新组合
公开(公告)号：WO2007089230A2
公开(公告)日：2007-08-09
申请号：PCT/US2006/003570
申请日：2006-02-01
申请人： NANOSET, LLC , WANG, Xingwu , GREENWALD, Howard, J.
发明人： WANG, Xingwu , GREENWALD, Howard, J.
IPC分类号： B32B19/02
CPC分类号： H01F1/0063 , A61K47/6949 , A61N2/06 , B82Y5/00 , B82Y25/00 , B82Y30/00 , C01P2004/64 , C01P2006/33 , C01P2006/42 , C04B35/628 , C04B35/62842 , C04B35/62892 , C04B35/62897 , C04B2235/349 , C09C1/42
摘要： A nanocomposite material containing a clay mineral disposed within a matrix selected from the group consisting of polymeric material, resin material, elastomeric material, ceramic material, and mixtures thereof. The clay mineral has a flexural strength of at least about 200 kilograms per square centimeter and a compressive strength of at least about 2,000 kilograms per square centimeter.
摘要翻译：一种纳米复合材料，其包含设置在由聚合材料，树脂材料，弹性体材料，陶瓷材料及其混合物组成的组中的基体内的粘土矿物。粘土矿物的抗弯强度至少约为200公斤/平方厘米，抗压强度至少约为2000公斤/平方厘米。

10. 发明申请

WO2006094191A2 COATED SUBSTRATE ASSEMBLY 审中-公开
标题翻译：涂层基板组件
公开(公告)号：WO2006094191A2
公开(公告)日：2006-09-08
申请号：PCT/US2006/007596
申请日：2006-03-02
申请人： NANOSET LLC , WANG, Xingwu , GREENWALD, Howard, J.
发明人： WANG, Xingwu , GREENWALD, Howard, J.
IPC分类号： A61L31/08 , A61L31/18 , A61N1/16 , A61N2/00 , A61N2/06 , H02J7/00
CPC分类号： A61N1/375 , A61L31/082 , A61L31/18 , A61N1/3718 , A61N2/002 , A61N2/06 , B82Y15/00 , B82Y20/00 , B82Y25/00 , H01F1/0045 , H01F1/26 , H01F1/342 , H01F1/37 , H01F1/44
摘要： Abstract of the disclosure A coated assembly with an inductance of from about 0.1 to about 5 nanohenries and a capacitance of from about 0.1 to about 10 nanofarads. The coated assembly contains a stent and a coating. When the assembly is exposed to radio frequency electromagnetic radiation with a frequency of from 10 megahertz to about 200 megahertz, at least 90 percent of the electromagnetic radiation penetrates to the interior of the stent.
摘要翻译：本公开的摘要具有约0.1至约5纳微秒的电感和约0.1至约10纳摩尔的电容的涂覆组件。涂覆的组件包含支架和涂层。当组件暴露于频率为10兆赫兹至约200兆赫兹的射频电磁辐射时，至少90％的电磁辐射渗透到支架内部。

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