专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明专利

BR9909207A 未知
公开(公告)号：BR9909207A
公开(公告)日：2001-11-06
申请号：BR9909207
申请日：1999-02-11
申请人： NANOGEN INC
发明人： ACKLEY DONALD E , SWANSON PAUL D , GRAHAM SCOTT O , MATHER ELIZABETH L , LECLAIR TIMOTHY L , BUTLER WILLIAM F
IPC分类号： G01N27/447 , B01L3/00 , C12M1/42 , G01N37/00 , G11C13/02 , G11C19/00 , C12M1/40

2. 发明专利

CA2320798C ADVANCED ACTIVE DEVICES AND METHODS FOR MOLECULAR BIOLOGICALANALYSIS AND DIAGNOSTICS 未知
公开(公告)号：CA2320798C
公开(公告)日：2008-01-15
申请号：CA2320798
申请日：1999-02-11
申请人： NANOGEN INC
发明人： GRAHAM SCOTT O , SWANSON PAUL D , ACKLEY DONALD E , MATHER ELIZABETH L , LECLAIR TIMOTHY L , BUTLER WILLIAM F
IPC分类号： C12M1/36 , G01N27/447 , B01L3/00 , C12M1/34 , C12M1/42 , C12Q1/68 , C40B60/00 , G01N37/00 , G11C13/02 , G11C19/00 , H01L21/58 , H01L25/00 , H01L27/00
摘要： Methods of manufacture and devices for performing active biological operatio ns utilize various structures to advantageously collect and provide charged biological materials to an array of microlocations. In o ne embodiment, a device includes focusing electrodes to aid in the direction and transport of materials from a collection electrode to a n array. Preferably, one or more intermediate transportation electrodes are utilized, most preferably of monotonically decreasing size between the collection electrode and the array, so as to reduce current density mismatches. In another aspect, a flow cell is utilized over devices to provide containment of solution containing materials to be analyzed. In yet another embodiment, a concentric ring design is provided. Various flip-chip embodiments are disclosed.

3. 发明专利

NZ506204A Advanced active devices and methods for molecular biological analysis and diagnostics 未知
公开(公告)号：NZ506204A
公开(公告)日：2003-06-30
申请号：NZ50620499
申请日：1999-02-11
申请人： NANOGEN INC
发明人： ACKLEY DONALD E , SWANSON PAUL D , GRAHAM SCOTT O , MATHER ELIZABETH L , LECLAIR TIMOTHY L , BUTLER WILLIAM F
IPC分类号： G01N27/447 , B01L3/00 , C12M1/42 , G01N37/00 , G11C13/02 , G11C19/00 , C12M1/40
摘要： An electronic device for performing active biological operations utilize various structures to advantageously collect and provide charged biological materials to an array of microlocations. The device includes focusing electrodes to aid in the direction and transport of materials from a collection electrode to an array. Preferably, one or more intermediate transportation electrodes are utilized, most preferably of monotonically decreasing size between the collection electrode and the array, so as to reduce current density mismatches. In another aspect, a flow cell is utilized over devices to provide containment of solution containing materials to be analyzed. In yet another embodiment, a concentric ring design is provided.

4. 发明申请

WO2009020609A2 ISOLATION OF NUCLEIC ACIDS MOLECULES USING MODIFIED SOLID SUPPORTS 审中-公开
标题翻译：用修饰的固体支持物分离核酸分子
公开(公告)号：WO2009020609A2
公开(公告)日：2009-02-12
申请号：PCT/US2008009427
申请日：2008-08-05
申请人： NANOGEN INC , WEISBURG WILLIAM G , MATHER ELIZABETH L , HAGHNIA MARJAN
发明人： MATHER ELIZABETH L , HAGHNIA MARJAN
IPC分类号： C12N15/10
CPC分类号： C12N15/1006
摘要： Provided are solid supports that contain at least one hydrophilic ligand; and at least one hydrophobic ligand, where amount of the at least one hydrophobic ligand on the solid support relative to the amount of the at least one hydrophilic ligand on the solid support is adjusted for binding target nucleic acid(s) from a sample onto the solid support and/or for eluting the bound target nucleic acid(s) from the solid support, so that the amount of target nucleic acid(s) bound to the solid support and/or recovered after elution from the solid support is about 5% to about 500% greater than the amount of target nucleic acid(s) bound to the solid support and/or recovered from the solid support in the absence of either the at least one hydrophobic ligand or the at least one hydrophilic ligand or both. The solid supports with ligands are used for isolation of nucleic acid molecules from samples.
摘要翻译：提供了含有至少一种亲水性配体的固体载体; 和至少一种疏水性配体，其中固体载体上的至少一种疏水性配体的量相对于固体载体上的至少一种亲水性配体的量被调节用于将来自样品的靶标核酸结合到固体支持物和/或用于从固体支持物上洗脱结合的靶核酸，使得结合到固体支持物上和/或从固体支持物洗脱后回收的靶核酸的量为约5％比在不存在所述至少一种疏水配体或所述至少一种亲水配体或两者的情况下从所述固体支持物结合的所述靶核酸的量大至约500％。具有配体的固体载体用于从样品中分离核酸分子。

5. 发明专利

AU742960B2 Advanced active devices and methods for molecular biological analysis and diagnostics 未知
公开(公告)号：AU742960B2
公开(公告)日：2002-01-17
申请号：AU2763899
申请日：1999-02-11
申请人： NANOGEN INC
发明人： ACKLEY DONALD E , SWANSON PAUL D , GRAHAM SCOTT O , MATHER ELIZABETH L , LECLAIR TIMOTHY L , BUTLER WILLIAM F
IPC分类号： G01N27/447 , B01L3/00 , C12M1/42 , G01N37/00 , G11C13/02 , G11C19/00 , C12M1/40

6. 发明专利

AU2763899A Advanced active devices and methods for molecular biological analysis and diagnostics 未知
公开(公告)号：AU2763899A
公开(公告)日：1999-09-06
申请号：AU2763899
申请日：1999-02-11
申请人： NANOGEN INC
发明人： ACKLEY DONALD E , SWANSON PAUL D , GRAHAM SCOTT O , MATHER ELIZABETH L , LECLAIR TIMOTHY L , BUTLER WILLIAM F
IPC分类号： G01N27/447 , B01L3/00 , C12M1/42 , G01N37/00 , G11C13/02 , G11C19/00 , C12M1/40

7. 发明专利

CA2320798A1 ADVANCED ACTIVE DEVICES AND METHODS FOR MOLECULAR BIOLOGICAL ANALYSIS AND DIAGNOSTICS 未知
公开(公告)号：CA2320798A1
公开(公告)日：1999-08-26
申请号：CA2320798
申请日：1999-02-11
申请人： NANOGEN INC
发明人： LECLAIR TIMOTHY L , ACKLEY DONALD E , BUTLER WILLIAM F , SWANSON PAUL D , MATHER ELIZABETH L , GRAHAM SCOTT O
IPC分类号： G01N27/447 , B01L3/00 , C12M1/42 , G01N37/00 , G11C13/02 , G11C19/00 , C12M1/40
摘要： Methods of manufacture and devices for performing active biological operations utilize various structures to advantageously collect and provide charged biological materials to an array of microlocations. In one embodiment, a device includes focusing electrodes to aid in the direction and transport of materials from a collection electrode to an array. Preferably, one or more intermediate transportation electrodes are utilized, most preferably of monotonically decreasing size between the collection electrode and the array, so as to reduce current density mismatches. In another aspect, a flow cell is utilized over devices to provide containment of solution containing materials to be analyzed. In yet another embodiment, a concentric ring design is provided. Various flip-chip embodiments are disclosed.

8. 发明公开

EP1054949A4 ADVANCED ACTIVE DEVICES AND METHODS FOR MOLECULAR BIOLOGICAL ANALYSIS AND DIAGNOSTICS 审中-公开
标题翻译：高级有源器件和法分子，生化分析及诊断
公开(公告)号：EP1054949A4
公开(公告)日：2006-09-27
申请号：EP99908135
申请日：1999-02-11
申请人： NANOGEN INC
发明人： ACKLEY DONALD E , SWANSON PAUL D , GRAHAM SCOTT O , MATHER ELIZABETH L , LECLAIR TIMOTHY L , BUTLER WILLIAM F
IPC分类号： G01N27/447 , B01L3/00 , C12M1/42 , G01N37/00 , G11C13/02 , G11C19/00 , C12M1/40 , B01J19/00
CPC分类号： G11C13/0019 , B01L3/502707 , B01L3/502715 , B01L3/502761 , B01L2200/0647 , B01L2300/0636 , B01L2300/0645 , B01L2300/0877 , B01L2400/0403 , B82Y10/00 , G11C13/0014 , G11C19/00 , H01L29/6656 , H01L2924/0002 , H01L2924/00
摘要： Methods of manufacture and devices for performing active biological operations utilize various structures to advantageously collect and provide charged biological materials to an array of microlocations. In one embodiment, a device includes focusing electrodes to aid in the direction and transport of materials from a collection electrode to an array. Preferably, one or more intermediate transportation electrodes are utilized, most preferably of monotonically decreasing size between the collection electrode and the array, so as to reduce current density mismatches. In another aspect, a flow cell is utilized over devices to provide containment of solution containing materials to be analyzed. In yet another embodiment, a concentric ring design is provided. Various flip-chip embodiments are disclosed.

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式