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1. 发明授权

US06191255B1 Protein and monoclonal antibody specific thereto 失效
标题翻译：与其特异的蛋白质和单克隆抗体
公开(公告)号：US06191255B1
公开(公告)日：2001-02-20
申请号：US09000041
申请日：1998-02-20
申请人： Motoharu Seiki , Hiroshi Sato , Akira Shinagawa
发明人： Motoharu Seiki , Hiroshi Sato , Akira Shinagawa
IPC分类号： A61K3843
CPC分类号： C12N9/6491 , A61K38/00 , C07K16/40 , Y02A50/473
摘要： A novel protein which is useful as a diagnostic means for studies relating to the diagnosis and treatment of cancer (detection of cancer cells, estimation of the malignity, etc.) and for other medicinal and physiological purposes; a gene encoding the same; and an antibody, in particular, a monoclonal antibody specific to the protein. MT-MMP-3, which is a pro MMP-2 activator having the ability to activate pro MMP-2 which is under expression specifically on the surface layer of a human cancer cell and falling within the category of MMP but being different from MT-MMP-1; a DNA containing the base sequence encoding the same; host cells transformed by the DNA; a process for producing a matrix metalloproteinase protein by using the host cells; a monoclonal antibody binding specifically to the matrix metalloproteinase protein; and use of the protein and antibody.
摘要翻译：一种新的蛋白质，其可用于诊断和治疗癌症的诊断手段（癌细胞的检测，恶性的估计等）和其他药物和生理目的; 编码该基因的基因; 和抗体，特别是针对蛋白质的单克隆抗体。 MT-MMP-3，其是具有活化pro MMP-2的能力的促MMP-2激活剂，其特异性在人癌细胞的表面上表达并且属于MMP类别，但不同于MT- MMP-1; 含有编码其的碱基序列的DNA; 由DNA转化的宿主细胞; 通过使用宿主细胞产生基质金属蛋白酶蛋白质的方法; 与基质金属蛋白酶蛋白特异性结合的单克隆抗体; 并使用蛋白质和抗体。

2. 发明授权

US06184022B2 Metalloproteinase and encoding DNA therefor 失效
标题翻译：金属蛋白酶和编码DNA
公开(公告)号：US06184022B2
公开(公告)日：2001-02-06
申请号：US08448489
申请日：1995-06-07
申请人： Motoharu Seiki , Hiroshi Sato , Akira Shinagawa
发明人： Motoharu Seiki , Hiroshi Sato , Akira Shinagawa
IPC分类号： C12N964
CPC分类号： C12N9/6491
摘要： A novel metalloproteinase, DNA encoding therefor, a plasmid carrying said DNA sequence and a host cell harbouring said plasmid, and monoclonal antibodies peculiarly recognizing said protein. Useful in applications pertaining to diagnosis of the presence of tumour cells, the degree of cancer malignancy, and other medical and physiological fields.
摘要翻译：一种新型金属蛋白酶，其编码的DNA，携带所述DNA序列的质粒和携带所述质粒的宿主细胞，以及特异性识别所述蛋白质的单克隆抗体。在诊断肿瘤细胞存在的程度，癌症恶性程度和其他医疗和生理领域。

3. 发明授权

US06825024B1 Metalloproteinase and encoding DNA therefor 失效
标题翻译：金属蛋白酶和编码DNA
公开(公告)号：US06825024B1
公开(公告)日：2004-11-30
申请号：US09689730
申请日：2000-10-13
申请人： Motoharu Seiki , Hiroshi Sato , Akira Shinagawa
发明人： Motoharu Seiki , Hiroshi Sato , Akira Shinagawa
IPC分类号： C12N964
CPC分类号： C12N9/6491
摘要： A novel metalloproteinase, DNA encoding therefor, a plasmid carrying said DNA sequence and a host cell harbouring said plasmid, and monoclonal antibodies peculiarly recognizing said protein. Useful in applications pertaining to diagnosis of the presence of tumour cells, the degree of cancer malignancy, and other medical and physiological fields.
摘要翻译：一种新型金属蛋白酶，其编码的DNA，携带所述DNA序列的质粒和携带所述质粒的宿主细胞，以及特异性识别所述蛋白质的单克隆抗体。在诊断肿瘤细胞存在的程度，癌症恶性程度和其他医疗和生理领域。

4. 发明授权

US06780412B2 Protein and monoclonal antibody specific thereto 失效
标题翻译：与其特异的蛋白质和单克隆抗体
公开(公告)号：US06780412B2
公开(公告)日：2004-08-24
申请号：US09734002
申请日：2000-12-12
申请人： Motoharu Seiki , Hiroshi Sato , Akira Shinagawa
发明人： Motoharu Seiki , Hiroshi Sato , Akira Shinagawa
IPC分类号： A61K39395
CPC分类号： C12N9/6491 , A61K38/00 , C07K16/40 , Y02A50/473
摘要： A novel protein which is useful as diagnostic means for the studies relating to the diagnosis and treatment of cancer (detection of cancer cells, estimation of the malignity, etc.) and in other medicinal and physiological purposes; a gene encoding the same; and an antibody, in particular, a monoclonal antibody specific to the protein. MT-MMP-3, which is a pro MMP-2 activator having the ability to activate pro MMP-2 which is under expression specifically on the surface layer of a human cancer cell and falling within the category of MMP but being different from MT-MMP-1; a DNA containing the base sequence encoding the same; host cells transformed by the DNA; a process for producing a matrix metalloproteinase protein by using the host cells; a monoclonal antibody binding specifically to the matrix metalloproteinase protein; and use of the protein and antibody.
摘要翻译：一种新的蛋白质，可用于诊断和治疗癌症（癌细胞的检测，恶性肿瘤的估计等）以及其他药物和生理目的的诊断手段; 编码该基因的基因; 和抗体，特别是针对蛋白质的单克隆抗体。 MT-MMP-3，其是具有活化pro MMP-2的能力的促MMP-2激活剂，其特异性在人癌细胞的表面上表达并且属于MMP类别，但不同于MT- MMP-1; 含有编码其的碱基序列的DNA; 由DNA转化的宿主细胞; 通过使用宿主细胞产生基质金属蛋白酶蛋白质的方法; 与基质金属蛋白酶蛋白特异性结合的单克隆抗体; 并使用蛋白质和抗体。

5. 发明申请

US20160331470A1 Location control system 审中-公开
标题翻译：位置控制系统
公开(公告)号：US20160331470A1
公开(公告)日：2016-11-17
申请号：US15111814
申请日：2015-01-09
申请人： Hiroshi Sato
发明人： Hiroshi Sato
IPC分类号： A61B34/20 , A61M1/00 , A61B90/11 , A61M5/158 , A61B17/3209 , A61B34/00
CPC分类号： A61B34/20 , A61B5/062 , A61B17/32093 , A61B34/30 , A61B34/35 , A61B34/73 , A61B90/11 , A61B2017/320052 , A61B2034/2051 , A61B2034/2059 , A61B2034/2065 , A61B2034/2072 , A61B2034/732 , A61B2090/061 , A61B2090/062 , A61B2090/374 , A61B2090/376 , A61B2090/3762 , A61B2090/378 , A61B2090/392 , A61B2090/3954 , A61B2090/3966 , A61B2218/002 , A61B2218/007 , A61M1/008 , A61M5/158 , A61M2005/1585 , G01B15/00
摘要： The embodiment of the present invention provides a position control system having a movement apparatus including an electromagnet capable of applying a magnetic field to a head and a movement control unit; and a position detection apparatus being capable of determining a position of a mark existing on the head or in a tip end side position of a pipe which is attached to the head with a tip end thereof open and through which a liquid can be injected or suctioned via an opening portion in the tip end, the position detection apparatus being capable of detecting a position of the head on the basis of the position of the mark, the movement control unit of the movement apparatus is capable of controlling an advancement direction of the head so that the pipe is inserted substantially linearly into a target position.
摘要翻译：本发明的实施例提供了一种位置控制系统，其具有包括能够向磁头施加磁场的电磁体和移动控制单元的移动装置; 以及位置检测装置，其能够确定存在于头部的标记的位置或附接到头部的管的前端侧位置，其顶端开口，并且可以通过该顶端喷射或吸引液体通过前端的开口部，位置检测装置能够根据标记的位置检测头部的位置，移动装置的移动控制单元能够控制头部的前进方向使得管道基本线性地插入目标位置。

6. 发明授权

US09244342B2 Imprint apparatus and pattern transfer method 有权
标题翻译：印刷装置和图案转印方法
公开(公告)号：US09244342B2
公开(公告)日：2016-01-26
申请号：US12963009
申请日：2010-12-08
申请人： Hiroshi Sato
发明人： Hiroshi Sato
IPC分类号： B29C59/02 , G03F7/00 , B82Y10/00 , B82Y40/00
CPC分类号： G03F7/0002 , B82Y10/00 , B82Y40/00
摘要： An imprint apparatus comprises a scope which observes a mark formed in each shot of a substrate and a mark formed on a mold and a controller. The controller performs observation by the scope, detects an amount of displacement of the shot with respect to the mold based on the observation result, and, if the detected displacement amount falls outside an allowable range, executes at least one of remeasuring a baseline amount and reexecuting a global alignment process.
摘要翻译：压印装置包括观察在基板的每个镜头中形成的标记的范围和形成在模具上的标记和控制器。控制器通过该范围进行观察，基于观察结果检测射出相对于模具的位移量，并且如果检测到的位移量超出允许范围，则执行重新测量基线量和重新执行全局对齐过程。

7. 发明授权

US09239946B2 Method and apparatus for detecting and processing specific pattern from image 有权
标题翻译：用于从图像中检测和处理特定图案的方法和装置
公开(公告)号：US09239946B2
公开(公告)日：2016-01-19
申请号：US13546355
申请日：2012-07-11
申请人： Kan Torii , Masakazu Matsugu , Katsuhiko Mori , Hiroshi Sato , Yusuke Mitarai
发明人： Kan Torii , Masakazu Matsugu , Katsuhiko Mori , Hiroshi Sato , Yusuke Mitarai
IPC分类号： G06K9/00 , H04N5/232
CPC分类号： G06K9/00234 , G06K2209/011 , H04N5/23219
摘要： In an image within which a face pattern is detected, when a ratio of a skin color pixel is equal to or smaller than a first threshold value in a first region and a ratio of a skin color pixel is equal to or greater than a second threshold value in a second r region, the vicinity of the first region is determined to be a face candidate position at which the face pattern can exist. Face detection is carried out on the face candidate position. The second region is arranged in a predetermined position relative to the first region.
摘要翻译：在其中检测到面部图案的图像中，当皮肤颜色像素的比例在第一区域中等于或小于第一阈值并且皮肤颜色像素的比率等于或大于第二阈值时在第二r区域中，第一区域附近被确定为可以存在脸部图案的面部候选位置。脸部检测在脸部候选位置进行。第二区域相对于第一区域布置在预定位置。

8. 发明授权

US08953175B2 Mark position detector, imprint apparatus, and article manufacturing method 有权
标题翻译：标记位置检测器，压印装置和制品制造方法
公开(公告)号：US08953175B2
公开(公告)日：2015-02-10
申请号：US12966237
申请日：2010-12-13
申请人： Hiroshi Sato
发明人： Hiroshi Sato
IPC分类号： G01B11/14 , G01B11/02 , G03F9/00 , G03F7/00
CPC分类号： G01B11/14 , B29C59/002 , B29C59/026 , B29K2101/00 , B29L2009/005 , B82Y10/00 , B82Y40/00 , G01B11/02 , G03F7/0002 , G03F9/7038 , G03F9/7042 , G03F9/7049 , G03F9/7088
摘要： A detector for detecting a position of a mark comprises: an image sensing device; an optical system which projects the mark onto an image sensing surface of the image sensing device; a pattern located in a position between the image sensing surface and an optical element located closest to a plane on which the mark is to be located, among optical elements forming the optical system, the position being optically conjugated with the plane; and a processor which calculates a position of the mark with respect to one of a position of the pattern and a position already known from the position of the pattern, based on a moire pattern formed on the image sensing surface by the mark and the pattern.
摘要翻译：用于检测标记位置的检测器包括：图像感测装置; 光学系统，其将标记投射到图像感测装置的图像感测表面上; 在形成光学系统的光学元件中位于图像感测表面和位于最靠近标记所在的平面的光学元件之间的位置的图案，该位置与该平面光学共轭; 以及处理器，其基于通过标记和图案形成在图像感测表面上的莫尔图案，计算相对于图案的位置和从图案的位置已知的位置之一的标记的位置。

9. 发明授权

US08861803B2 Image recognition apparatus, image recognition method, and program 有权
标题翻译：图像识别装置，图像识别方法和程序
公开(公告)号：US08861803B2
公开(公告)日：2014-10-14
申请号：US13436585
申请日：2012-03-30
申请人： Kotaro Yano , Hiroshi Sato , Shunsuke Nakano
发明人： Kotaro Yano , Hiroshi Sato , Shunsuke Nakano
IPC分类号： G06K9/46 , G06K9/00
CPC分类号： G06K9/00281
摘要： An image recognition apparatus includes an extraction unit configured to extract a feature quantity for each local area from an input image, a conversion unit configured to convert the feature quantity extracted by the extraction unit into a feature quantity indicating a degree with respect to an attribute for each local area, a verification unit configured to verify the feature quantity converted by the conversion unit against a feature quantity of a registered image, and an identification unit configured to identify whether the input image is identical to the registered image by integrating the verification result for each local area acquired by the verification unit.
摘要翻译：图像识别装置包括：提取单元，被配置为从输入图像中提取每个局部区域的特征量;转换单元，被配置为将由提取单元提取的特征量转换为指示相对于属性的属性的度数的特征量每个局部区域，验证单元，被配置为验证由转换单元转换的特征量相对于注册图像的特征量;以及识别单元，被配置为通过将输入图像与登记图像相一致来识别，验证单位获取的每个局部区域。

10. 发明授权

US08842880B2 Information processing apparatus, method of controlling information processing apparatus, and storage medium 有权
标题翻译：信息处理装置，信息处理装置的控制方法以及存储介质
公开(公告)号：US08842880B2
公开(公告)日：2014-09-23
申请号：US13444738
申请日：2012-04-11
申请人： Shunsuke Nakano , Hiroshi Sato , Yuji Kaneda , Takashi Suzuki
发明人： Shunsuke Nakano , Hiroshi Sato , Yuji Kaneda , Takashi Suzuki
IPC分类号： G06K9/00 , G06F3/00
CPC分类号： G06K9/00288
摘要： An information processing apparatus comprising: an obtaining unit configured to obtain image data; a detection unit configured to detect an object from the image data; an attribute determination unit configured to determine an attribute indicating a characteristic of the object detected by the detection unit; a registration unit configured to register the image data in at least one of a plurality of dictionaries based on the attribute determined by the attribute determination unit; and an adding unit configured to add, when the image data is registered in not less than two dictionaries, link information concerning the image data registered in the other dictionary to the image data registered in one dictionary.
摘要翻译：一种信息处理设备，包括：获取单元，被配置为获得图像数据; 检测单元，被配置为从所述图像数据检测对象; 属性确定单元，被配置为确定指示由所述检测单元检测到的所述对象的特征的属性; 注册单元，被配置为基于由属性确定单元确定的属性将多个字典中的至少一个注册图像数据; 以及添加单元，被配置为当图像数据在不少于两个字典中登记时，将登记在其他字典中的图像数据的链接信息添加到登记在一个字典中的图像数据。

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