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1. 发明申请

US20120329887A1 BIODEGRADABLE POLYORGANOSILOXANE DEMULSIFIER COMPOSITION AND METHOD FOR MAKING THE SAME 有权
标题翻译：可生物降解的聚羟基烷氧基化合物组合物及其制备方法
公开(公告)号：US20120329887A1
公开(公告)日：2012-12-27
申请号：US13165085
申请日：2011-06-21
申请人： Monjit PHUKAN , Anubhav Saxena , Mayank Kumar Dubey , Antonio Palumbo , Kalman Koczo
发明人： Monjit PHUKAN , Anubhav Saxena , Mayank Kumar Dubey , Antonio Palumbo , Kalman Koczo
IPC分类号： B01D17/00
CPC分类号： C08L83/12 , B01D17/047 , C08G77/46 , C10G33/04
摘要： There is provided herein a demulsifying composition comprising at least one polyorganosiloxane compound having the general formula (I): M1aM2bD1cD2dT1eT2fQg (I) wherein: M1=R1R2R3SiO1/2, M2=R4R5RLSiO1/2, D1=R6R7SiO2/2, D2=R8RLSiO2/2, T1=R9SiO3/2, T2=RLSiO3/2, Q=SiO4/2, where R1, R2, R3, R4, R5, R6, R7, R8 and R9 are each independently chosen from monovalent alkyl, aryl or aralkyl hydrocarbon radicals, or chosen from RP; RP is a monovalent polyether radical independently of the general formula (II): —(CnH2n)—O—(C2H4O)o—(C3H6O)p—(C4H8O)q—R10 (II) RL is a monovalent radical independently chosen from the general formula (III): —X—O—(C2H4O)r—(C3H6O)s—(C4H8O)t—{C(O)CuH2uO}v—R11 (III). There is also provided herein a method for separating emulsions comprising combining the components of the demulsification composition into a mixture; allowing the mixture to separate into at least two phases and separating said at least two phases from each other.
摘要翻译：本文提供了包含至少一种具有通式（I）的聚有机硅氧烷化合物的破乳组合物：M1aM2bD1cD2dT1eT2fQg（I）其中：M1 = R1R2R3SiO1 / 2，M2 = R4R5RLSiO1 / 2，D1 = R6R7SiO2 / 2，D2 = R8RLSiO2 / 2 ，T1 = R9SiO3 / 2，T2 = RLSiO3 / 2，Q = SiO4 / 2，其中R1，R2，R3，R4，R5，R6，R7，R8和R9各自独立地选自一价烷基，芳基或芳烷基烃基，或从RP中选择; RP是独立于通式（II）的单价聚醚基： - （C n H 2n）-O-（C 2 H 4 O）O-（C 3 H 6 O）p - （C 4 H 8 O）q -R 10（II）RL是独立地选自通式（III）：-X-O-（C 2 H 4 O）r - （C 3 H 6 O）s - （C 4 H 8 O）t - {C（O）Cu H 2uO} v -R 11（III）。本文还提供了用于分离乳液的方法，其包括将破乳组合物的组分混合成混合物; 允许混合物分离成至少两相，并将所述至少两相彼此分离。

2. 发明授权

US08779012B2 Biodegradable polyorganosiloxane demulsifier composition and method for making the same 有权
标题翻译：可生物降解聚有机硅氧烷破乳剂组合物及其制备方法
公开(公告)号：US08779012B2
公开(公告)日：2014-07-15
申请号：US13165085
申请日：2011-06-21
申请人： Monjit Phukan , Anubhav Saxena , Mayank Kumar Dubey , Antonio Palumbo , Kalman Koczo
发明人： Monjit Phukan , Anubhav Saxena , Mayank Kumar Dubey , Antonio Palumbo , Kalman Koczo
IPC分类号： B01D17/00
CPC分类号： C08L83/12 , B01D17/047 , C08G77/46 , C10G33/04
摘要： There is provided herein a demulsifying composition comprising at least one polyorganosiloxane compound having the general formula (I): M1aM2bD1cD2dT1eT2fQg (I) wherein: M1=R1R2R3SiO1/2, M2=R4R5RLSiO1/2, D1=R6R7SiO2/2, D2=R8RLSiO2/2, T1=R9SiO3/2, T2=RLSiO3/2, Q=SiO4/2, where R1, R2, R3, R4, R5, R6, R7, R8 and R9 are each independently chosen from monovalent alkyl, aryl or aralkyl hydrocarbon radicals, or chosen from RP; RP is a monovalent polyether radical independently of the general formula (II): —(CnH2n)—O—(C2H4O)o—(C3H6O)p—(C4H8O)q—R10 (II) RL is a monovalent radical independently chosen from the general formula (III): —X—O—(C2H4O)r—(C3H6O)s—(C4H8O)t—{C(O)CuH2uO}v—R11 (III) There is also provided herein a method for separating emulsions comprising combining the components of the demulsification composition into a mixture; allowing the mixture to separate into at least two phases and separating said at least two phases from each other.
摘要翻译：本文提供了包含至少一种具有通式（I）的聚有机硅氧烷化合物的破乳组合物：M1aM2bD1cD2dT1eT2fQg（I）其中：M1 = R1R2R3SiO1 / 2，M2 = R4R5RLSiO1 / 2，D1 = R6R7SiO2 / 2，D2 = R8RLSiO2 / 2 ，T1 = R9SiO3 / 2，T2 = RLSiO3 / 2，Q = SiO4 / 2，其中R1，R2，R3，R4，R5，R6，R7，R8和R9各自独立地选自一价烷基，芳基或芳烷基烃基，或从RP中选择; RP是独立于通式（II）的单价聚醚基： - （C n H 2n）-O-（C 2 H 4 O）O-（C 3 H 6 O）p - （C 4 H 8 O）q -R 10（II）RL是独立地选自通式（III）：-X-O-（C 2 H 4 O）r - （C 3 H 6 O）s - （C 4 H 8 O）t- {C（O）Cu H 2u O} v-R 11（III）本文还提供了分离乳液的方法，将破乳组合物的组分混合成混合物; 允许混合物分离成至少两相，并将所述至少两相彼此分离。

3. 发明申请

US20130338606A1 SELF-LUBRICATING PHARMACEUTICAL SYRINGE STOPPERS 有权
标题翻译：自润滑药液灭火器
公开(公告)号：US20130338606A1
公开(公告)日：2013-12-19
申请号：US13968974
申请日：2013-08-16
申请人： Samuel Conzone , David M. Rusinko , Chandrashekar Raman , Indumathi Ramakrishnan , Anantharaman Dhanabalan , Mayank Kumar Dubey , Markus Bley , Hans Rafael Winkelbach
发明人： Samuel Conzone , David M. Rusinko , Chandrashekar Raman , Indumathi Ramakrishnan , Anantharaman Dhanabalan , Mayank Kumar Dubey , Markus Bley , Hans Rafael Winkelbach
IPC分类号： A61M5/315
CPC分类号： A61M5/31513 , A61M5/31511 , A61M2005/3131 , C10M169/04 , C10M2201/041 , C10M2201/061 , C10M2201/066 , C10M2201/103 , C10M2201/105 , C10M2205/20 , C10M2205/203 , C10M2207/126 , C10M2207/28 , C10M2207/283 , C10M2213/062 , C10M2215/08 , C10M2229/02 , C10M2229/025 , C10M2229/04 , C10M2229/051 , C10N2230/06 , C10N2240/66
摘要： In one aspect, a self-lubricating component is provided for a pharmaceutical packaging assembly. The self-lubricating component comprises a polymer composition and an effective amount of a lubricating additive such as, for example, boron nitride. In another aspect, a pharmaceutical packaging assembly may be provided having a surface thereof coated with a lubricating composition comprising boron nitride. The pharmaceutical packaging composition may be, for example, a pre-filled syringe comprising a body (barrel) and a plunger assembly.
摘要翻译：一方面，为药物包装组件提供自润滑部件。自润滑组分包括聚合物组合物和有效量的润滑添加剂，例如氮化硼。在另一方面，可以提供药物包装组件，其具有其表面涂覆有包含氮化硼的润滑组合物。药物包装组合物可以是例如包括主体（筒）和柱塞组件的预填充注射器。

4. 发明申请

US20120065595A1 SELF-LUBRICATING PHARMACEUTICAL SYRINGE STOPPERS 有权
标题翻译：自润滑药液灭火器
公开(公告)号：US20120065595A1
公开(公告)日：2012-03-15
申请号：US13227625
申请日：2011-09-08
申请人： Samuel D. Conzone , David M. Rusinko , Chandrashekar Raman , Indumathi Ramakrishnan , Anantharaman Dhanabalan , Mayank Kumar Dubey , Sumi Dinkar , Mayanglambam Rebika Devi , Markus Bley
发明人： Samuel D. Conzone , David M. Rusinko , Chandrashekar Raman , Indumathi Ramakrishnan , Anantharaman Dhanabalan , Mayank Kumar Dubey , Sumi Dinkar , Mayanglambam Rebika Devi , Markus Bley
IPC分类号： A61M5/315 , C10M125/02
CPC分类号： A61M5/31513 , A61M2005/3131 , C10M169/04 , C10M2201/041 , C10M2201/061 , C10M2201/066 , C10M2201/103 , C10M2201/105 , C10M2205/20 , C10M2205/203 , C10M2207/126 , C10M2207/28 , C10M2207/283 , C10M2213/062 , C10M2215/08 , C10M2229/02 , C10M2229/025 , C10M2229/04 , C10M2229/051 , C10N2230/06 , C10N2240/66
摘要： In one aspect, a self-lubricating component is provided for a pharmaceutical packaging assembly. The self-lubricating component comprises a polymer composition and an effective amount of a lubricating additive such as, for example, boron nitride. In another aspect, a pharmaceutical packaging assembly may be provided having a surface thereof coated with a lubricating composition comprising boron nitride. The pharmaceutical packaging composition may be, for example, a pre-filled syringe comprising a body (barrel) and a plunger assembly.
摘要翻译：一方面，为药物包装组件提供自润滑部件。自润滑组分包含聚合物组合物和有效量的润滑添加剂，例如氮化硼。在另一方面，可以提供药物包装组件，其具有其表面涂覆有包含氮化硼的润滑组合物。药物包装组合物可以是例如包括主体（筒）和柱塞组件的预填充注射器。

5. 发明授权

US08530536B2 Self-lubricating pharmaceutical syringe stoppers 有权
公开(公告)号：US08530536B2
公开(公告)日：2013-09-10
申请号：US13227625
申请日：2011-09-08
申请人： Samuel D. Conzone , David M. Rusinko , Chandrashekar Raman , Indumathi Ramakrishnan , Anantharaman Dhanabalan , Mayank Kumar Dubey , Sumi Dinkar , Mayanglambam Rebika Devi , Markus Bley
发明人： Samuel D. Conzone , David M. Rusinko , Chandrashekar Raman , Indumathi Ramakrishnan , Anantharaman Dhanabalan , Mayank Kumar Dubey , Sumi Dinkar , Mayanglambam Rebika Devi , Markus Bley
IPC分类号： C08J5/16
CPC分类号： A61M5/31513 , A61M2005/3131 , C10M169/04 , C10M2201/041 , C10M2201/061 , C10M2201/066 , C10M2201/103 , C10M2201/105 , C10M2205/20 , C10M2205/203 , C10M2207/126 , C10M2207/28 , C10M2207/283 , C10M2213/062 , C10M2215/08 , C10M2229/02 , C10M2229/025 , C10M2229/04 , C10M2229/051 , C10N2230/06 , C10N2240/66
摘要： In one aspect, a self-lubricating component is provided for a pharmaceutical packaging assembly. The self-lubricating component comprises a polymer composition and an effective amount of a lubricating additive such as, for example, boron nitride. In another aspect, a pharmaceutical packaging assembly may be provided having a surface thereof coated with a lubricating composition comprising boron nitride. The pharmaceutical packaging composition may be, for example, a pre-filled syringe comprising a body (barrel) and a plunger assembly.

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