专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明授权

US11068694B2 Image analysis system and method of using the image analysis system 有权
公开(公告)号：US11068694B2
公开(公告)日：2021-07-20
申请号：US16254823
申请日：2019-01-23
申请人： Molecular Devices, LLC
发明人： Avrum Cohen , Dihui Hong , Stephen Rhein
IPC分类号： G06K9/00 , G06K9/62 , G06T7/00
摘要： A system and method for analyzing images using a non-transitory programmable device is disclosed. A user interface generator operating on the non-transitory programmable device receives specifications of a first image of a biological sample and a first image analysis step. A sequencer operating on the non-transitory programmable device applies the first image analysis step to the first image to develop annotated training data, and a machine learning system trainer operating on the non-transitory programmable device trains an untrained machine learning system to develop a trained machine learning system. When the trained machine learning system is presented with the first image as an input, the trained machine learning system develops a prediction of the annotated training data. In addition, the sequencer receives a specification of a workflow that comprises a second image analysis step that specifies operating the trained machine learning system and the sequencer undertakes the workflow on a second image to analyze the second image.

2. 发明申请

US20180276827A1 System and Method for Segmentation of Three-Dimensional Microscope Images 审中-公开
公开(公告)号：US20180276827A1
公开(公告)日：2018-09-27
申请号：US15980192
申请日：2018-05-15
申请人： Molecular Devices, LLC
发明人： Dihui Hong , Avrum Cohen
IPC分类号： G06T7/11
CPC分类号： G06T7/11 , G06T7/136 , G06T2207/10056 , G06T2207/30204
摘要： A system and method to segment an image captured from an image capture device of a high content imaging system includes an image acquisition module that receives the image captured by the image capture device. A coarse object detection module develops a coarse segmented image, wherein each pixel of the coarse segmented image is associated with a corresponding pixel in the captured image and is identified as one of an object pixel and a background pixel. A marker identification module selects at least one marker pixel from the pixels of the coarse segmented image, wherein each marker pixel is one of a contiguous group of object pixels in the coarse segmented image that is furthest from a background pixel relative to neighboring pixels of the group. An object splitting module that comprises a plurality of processors operating in parallel that associates each object pixel of the coarse segmented image with a marker pixel, wherein a distance based metric between the object pixel and the marker pixel is less than the distance based metric between the object pixel and any other marker pixel in the coarse segmented image.

3. 发明授权

US11334743B2 System and method for image analysis of multi-dimensional data 有权
公开(公告)号：US11334743B2
公开(公告)日：2022-05-17
申请号：US16894267
申请日：2020-06-05
申请人： MOLECULAR DEVICES, LLC
发明人： Avrum Cohen , Dihui Hong , Steven Luke
IPC分类号： G06K9/00 , G02B21/36 , G06T7/00
摘要： A computer-implemented system and method for analyzing a biological sample are disclosed. A sequence of images of the biological sample from an image capture device are received from an image capture device, wherein each image of the sequence of images is acquired at a particular focal plane of the biological sample. In addition, an object map is developed from the sequence of images and the object map is analyzed to measure a three-dimensional characteristic of a particular object. The object map comprises a plurality of object map planes, each object map plane is associated with one image of the sequence of images, and pixels of the object map planes associated with the particular object in the sequence of images are assigned a unique identifier associated with the particular object.

4. 发明授权

US09928403B2 System and method for image analysis of multi-dimensional data 有权
公开(公告)号：US09928403B2
公开(公告)日：2018-03-27
申请号：US15019411
申请日：2016-02-09
申请人： Molecular Devices LLC
发明人： Avrum Cohen , Dihui Hong , Steven Luke
IPC分类号： G06K9/00 , G02B21/36 , G06T7/00
CPC分类号： G06K9/0014 , G02B21/365 , G06K9/00134 , G06T7/0012 , G06T2200/24 , G06T2200/28 , G06T2207/30024
摘要： A system and method for analyzing multi-dimensional images includes a high content imaging system that includes an image capture device. An image acquisition module receives a series of images of a biological sample captured by the image capture device, and the series of images includes a sequence of image planes. A human interface module receives from a user computer specifications of a first image analysis step and a second image analysis step. The first image analysis step specifies a first image processing operation that processes an image plane of a series of images in accordance with at least another image plane of the series of images and the second image analysis step specifies a second image processing operation that processes each image plane of a series of images independently of the other image planes of the series. An image analysis module having a plurality of processors operating in parallel processes the first series of images in accordance with the first image processing step to generate a first output series of images, and processes the first series of images in accordance with second image processing step to generate a second output series of images. The human interface module displays at least one image plane of the first output series of images and at least one image plane of the second output series of images on a display associated with the user computer.

5. 发明授权

US09754378B2 System and method for segmentation of three-dimensional microscope images 有权
公开(公告)号：US09754378B2
公开(公告)日：2017-09-05
申请号：US15003302
申请日：2016-01-21
申请人： Molecular Devices, LLC
发明人： Dihui Hong , Avrum Cohen
IPC分类号： G06K9/34 , G06T7/00
CPC分类号： G06T7/11 , G06T7/136 , G06T2207/10056 , G06T2207/30204
摘要： A system and method to segment an image captured from an image capture device of a high content imaging system includes an image acquisition module that receives the image captured by the image capture device. A coarse object detection module develops a coarse segmented image, wherein each pixel of the coarse segmented image is associated with a corresponding pixel in the captured image and is identified as one of an object pixel and a background pixel. A marker identification module selects at least one marker pixel from the pixels of the coarse segmented image, wherein each marker pixel is one of a contiguous group of object pixels in the coarse segmented image that is furthest from a background pixel relative to neighboring pixels of the group. An object splitting module that comprises a plurality of processors operating in parallel that associates each object pixel of the coarse segmented image with a marker pixel, wherein a distance based metric between the object pixel and the marker pixel is less than the distance based metric between the object pixel and any other marker pixel in the coarse segmented image.

6. 发明申请

US20200382715A1 SYSTEM AND METHOD TO CORRECT FOR VARIATION OF IN-FOCUS PLANE ACROSS A FIELD OF VIEW OF A MICROSCOPE OBJECTIVE 审中-公开
公开(公告)号：US20200382715A1
公开(公告)日：2020-12-03
申请号：US16429955
申请日：2019-06-03
申请人： Molecular Devices, LLC
发明人： Dihui Hong , Stephen Rhein , Avrum Cohen , Steve Luke
IPC分类号： H04N5/232 , H04N5/225 , G02B21/36 , G02B7/38 , G02B21/24
摘要： A computer implemented system and method for generating a focus corrected image of a sample disposed on a sample holder of an imaging system is disclosed. The imaging system includes an image sensor and a lens moveable relative to the image sensor between a first position and a second position. A characteristic map of the lens is developed that associates coordinates of each pixel of an image generated by the imaging sensor with one of a first plurality of locations of the lens between the first position and the second position. An image generator develops an output pixel of a focus-corrected image of a sample from a plurality of images of the sample acquired when the lens is positioned at a corresponding one of a second plurality of locations of the lens between the first position and the second position. The image generator selects a second location in accordance with the characteristic map, an image from the plurality of images of the sample associated with the second location, and determines a value of the output pixel in accordance with a value of a pixel of the selected one of the plurality of images that corresponds to the output pixel.

7. 发明申请

US20200311377A1 System and Method for Image Analysis of Multi-Dimensional Data 审中-公开
公开(公告)号：US20200311377A1
公开(公告)日：2020-10-01
申请号：US16894267
申请日：2020-06-05
申请人： MOLECULAR DEVICES, LLC
发明人： Avrum Cohen , Dihui Hong , Steven Luke
IPC分类号： G06K9/00 , G02B21/36 , G06T7/00
摘要： A computer-implemented system and method for analyzing a biological sample are disclosed. A sequence of images of the biological sample from an image capture device are received from an image capture device, wherein each image of the sequence of images is acquired at a particular focal plane of the biological sample. In addition, an object map is developed from the sequence of images and the object map is analyzed to measure a three-dimensional characteristic of a particular object. The object map comprises a plurality of object map planes, each object map plane is associated with one image of the sequence of images, and pixels of the object map planes associated with the particular object in the sequence of images are assigned a unique identifier associated with the particular object.

8. 发明授权

US10169878B2 System and method for segmentation of three-dimensional microscope images 有权
公开(公告)号：US10169878B2
公开(公告)日：2019-01-01
申请号：US15980192
申请日：2018-05-15
申请人： Molecular Devices, LLC
发明人： Dihui Hong , Avrum Cohen
IPC分类号： G06K9/34 , G06T7/11 , G06T7/136
摘要： A system and method to segment an image captured from an image capture device of a high content imaging system includes an image acquisition module that receives the image captured by the image capture device. A coarse object detection module develops a coarse segmented image, wherein each pixel of the coarse segmented image is associated with a corresponding pixel in the captured image and is identified as one of an object pixel and a background pixel. A marker identification module selects at least one marker pixel from the pixels of the coarse segmented image, wherein each marker pixel is one of a contiguous group of object pixels in the coarse segmented image that is furthest from a background pixel relative to neighboring pixels of the group. An object splitting module that comprises a plurality of processors operating in parallel that associates each object pixel of the coarse segmented image with a marker pixel, wherein a distance based metric between the object pixel and the marker pixel is less than the distance based metric between the object pixel and any other marker pixel in the coarse segmented image.

9. 发明申请

US20180247102A1 System and Method for Image Analysis of Multi-Dimensional Data 审中-公开
公开(公告)号：US20180247102A1
公开(公告)日：2018-08-30
申请号：US15897699
申请日：2018-02-15
申请人： Molecular Devices, LLC
发明人： Avrum Cohen , Dihui Hong , Steven Luke
IPC分类号： G06K9/00 , G02B21/36 , G06T7/00
摘要： A system and method for analyzing multi-dimensional images includes a high content imaging system that includes an image capture device. An image acquisition module receives a series of images of a biological sample captured by the image capture device, and the series of images includes a sequence of image planes. A human interface module receives from a user computer specifications of a first image analysis step and a second image analysis step. The first image analysis step specifies a first image processing operation that processes an image plane of a series of images in accordance with at least another image plane of the series of images and the second image analysis step specifies a second image processing operation that processes each image plane of a series of images independently of the other image planes of the series. An image analysis module having a plurality of processors operating in parallel processes the first series of images in accordance with the first image processing step to generate a first output series of images, and processes the first series of images in accordance with second image processing step to generate a second output series of images. The human interface module displays at least one image plane of the first output series of images and at least one image plane of the second output series of images on a display associated with the user computer.

10. 发明申请

US20210326565A1 IMAGE ANALYSIS SYSTEM AND METHOD OF USING THE IMAGE ANALYSIS SYSTEM 有权
公开(公告)号：US20210326565A1
公开(公告)日：2021-10-21
申请号：US17365710
申请日：2021-07-01
申请人： Molecular Devices, LLC
发明人： Avrum Cohen , Dihui Hong , Stephen Rhein
IPC分类号： G06K9/00 , G06K9/62 , G06T7/00
摘要： A system and method for analyzing images using programmable device is disclosed. A sequencer operating on the non-transitory programmable device applies the first image analysis step to the first image to develop annotated training data. Specifications of the first image and the first image analysis step are developed using a graphical user interface operating on a computer. In addition, a machine learning system trainer operating on the programmable device trains an untrained machine learning system to develop a trained machine learning system. When the trained machine learning system is presented with the first image as an input, the trained machine learning system develops a prediction of the annotated training data. In addition, the sequencer analyzes a second image by undertaking a workflow, wherein the workflow is received from the computer and is specified using the graphical user interface and comprises a second image analysis step that that specifies operating the trained machine learning system

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式