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    • 1. 发明授权
    • Optical information recording medium and methods for recording, reading, and erasing information thereupon
    • 光学信息记录介质以及用于记录,读取和擦除信息的方法
    • US06606293B1
    • 2003-08-12
    • US09478701
    • 2000-01-06
    • Mitsuya OkadaShuichi OhkuboMasaki Itoh
    • Mitsuya OkadaShuichi OhkuboMasaki Itoh
    • G11B70037
    • G11B7/257G11B7/24G11B7/243G11B7/252G11B7/258G11B2007/24312G11B2007/24314G11B2007/24316
    • There is disclosed an optical information recording medium having phase-change recording films whose the transmittance can be made substantially uniform irrespective of the presence or absence of recording. There are also disclosed methods for recording, reading, and erasing information well at a high density on such a medium. Each of the phase-change recording films other than the top one has a phase-change recording film for recording and erasing information by a phase change caused by illumination of laser light. A transparent upper protective film is formed on the phase-change recording film to protect the phase-change recording film mainly against thermal deformation during recording and erasing of information. A transparent lower protective film is formed under the phase-change recording film to protect the phase-change recording film mainly against thermal deformation during recording and erasing of information. A foundation interference film is formed under the transparent lower protective film to adjust the transmittance of the phase-change recording film for the laser light.
    • 公开了一种具有相变记录膜的光学信息记录介质,其透射率可以基本上均匀,而不管记录是否存在。 还公开了在这种介质上高密度地记录,读取和擦除信息的方法。 除了顶部之外的每个相变记录膜具有用于通过由激光的照明引起的相位变化来记录和擦除信息的相变记录膜。 在相变记录膜上形成透明的上保护膜,以在记录和擦除信息期间主要防止相变记录膜的热变形。 在相变记录膜下面形成透明的下保护膜,以在记录和擦除信息期间主要防止相变记录膜的热变形。 在透明下保护膜下方形成基础干涉膜,以调节激光用相变记录膜的透射率。
    • 3. 发明授权
    • Phase change optical disk and a method for recording and playbacking
optical information on or from an optical disk
    • 相变光盘以及在光盘上记录和重放光学信息的方法
    • US5862122A
    • 1999-01-19
    • US956781
    • 1997-10-23
    • Mitsuya OkadaShuichi Ohkubo
    • Mitsuya OkadaShuichi Ohkubo
    • B41M5/26G11B7/0055G11B7/007G11B7/24G11B7/243G11B7/254
    • G11B7/243G11B7/00557G11B7/00718G11B2007/24312G11B2007/24314G11B2007/24316G11B7/2534G11B7/2542G11B7/2585
    • The optical phase difference between reflected laser light from the crystalline and the amorphous part of a phase change recording layer is established as 180 degrees .+-.5 degrees. The ratio between the light absorption factor when the phase change recording film is in the crystalline condition to that when it is in the amorphous condition is set to within the range 0.9 to 1.1. With the wavelength of the laser light used as .lambda., the optical depth of a guide groove formed on the substrate is set to within the range .lambda./9 to .lambda./6. With the wavelength of the laser light used in the range 635 nm to 650 nm, the depth of the guide groove is in the range 40 to 70 nm. In an optical disk such as this, when seen from reflected light, the groove region of a groove during playback and land region of the groove during playback are optically equivalent. For this reason, it is substantially the same as the case in which the optical phase difference between the reflected laser light from the crystalline part of the recording film and the reflected laser light from the amorphous part of the recording film is zero, this making it possible to achieve consistency in the signal levels between land playback and groove playback. As a result, it is possible to perform double track density recording and mark edge recording.
    • 来自晶体的反射激光与相变记录层的非晶部分之间的光学相位差建立为180度+/- 5度。 当相变记录膜处于结晶状态时的光吸收系数与处于非晶态的光吸收系数之间的比率设定在0.9〜1.1的范围内。 在激光的波长为λ的情况下,将形成在基板上的引导槽的光学深度设定在λ/ 9〜λ/ 6的范围内。 使用在635nm至650nm范围内的激光的波长,导向槽的深度在40至70nm的范围内。 在这样的光盘中,当从反射光中观察时,回放期间的槽的槽区域和回放期间的槽的槽脊区域在光学上相当。 因此,与记录膜的结晶部分的反射激光和记录膜的非晶部分的反射激光之间的光学相位差为零的情况基本相同,这使得 可以实现陆地播放和凹槽播放之间信号水平的一致性。 结果,可以进行双轨密度记录和标记边缘记录。
    • 7. 发明申请
    • NOVEL BICYCLIC COMPOUND OR SALT THEREOF
    • 新型双环化合物或其盐
    • US20130296320A1
    • 2013-11-07
    • US13978613
    • 2012-01-06
    • Makoto KitadeSatoshi YamashitaShuichi Ohkubo
    • Makoto KitadeSatoshi YamashitaShuichi Ohkubo
    • C07D401/14C07D403/14C07D403/04C07D417/04C07D413/04C07D401/04C07D471/04
    • C07D403/04A61K31/4375A61K31/4709A61K31/4725A61K31/497A61K31/501A61K31/506A61K31/517A61K31/5377C07D401/04C07D401/14C07D403/14C07D413/04C07D417/04C07D471/04
    • Provided is a novel bicyclic compound which has an HSP90 inhibitory effect and a carcinostatic effect. Also provided is a pharmaceutical agent which is based on the HSP90 inhibitory effect and is useful in the prevention and/or treatment of a disease involving HSP90, particularly, cancer. The present invention provides a compound represented by the following general formula (I) or a salt thereof wherein at least one of X1, X2, X3, and X4 represents N or N-oxide and the rest thereof are the same or different and each represent C—R2; any one or two of Y1, Y2, Y3, and Y4 represent C—R4 and the rest thereof are the same or different and each represent CH or N; R1 represents an optionally substituted monocyclic or bicyclic unsaturated heterocyclic group having 1 to 4 heteroatoms selected from N, S, and O; R2 represents a hydrogen atom, an optionally substituted alkyl group having 1 to 6 carbon atoms etc.; R3 represents a hydrogen atom, —CO—R5 etc.; R4 represents a hydrogen atom, —CO—R6, —N(R7)(R8) etc.; R5 represents a hydroxyl group, an amino group etc.; R6 represents a hydroxyl group etc.; R7 and R8 are the same or different and each represent a hydrogen atom, an optionally substituted alkyl group having 1 to 6 carbon atoms etc.; and R9 represents an optionally substituted cycloalkyl group having 3 to 7 carbon atoms etc.
    • 提供具有HSP90抑制作用和制癌作用的新型双环化合物。 还提供了基于HSP90抑制作用的药剂,并且可用于预防和/或治疗涉及HSP90,特别是癌症的疾病。 本发明提供由以下通式(I)表示的化合物或其盐,其中X 1,X 2,X 3和X 4中的至少一个表示N或N-氧化物,其余的相同或不同,表示 C-R2; Y1,Y2,Y3和Y4中的任何一个或两个表示C-R 4,其余的相同或不同,各自表示CH或N; R1表示具有1至4个选自N,S和O的杂原子的任选取代的单环或双环不饱和杂环基; R2表示氢原子,可以具有取代基的碳原子数1〜6的烷基等。 R3表示氢原子,-CO-R5等; R4代表氢原子,-CO-R6,-N(R7)(R8)等; R5代表羟基,氨基等; R6表示羟基等。 R 7和R 8相同或不同,各自表示氢原子,可以具有取代基的碳原子数1〜6的烷基等。 R9表示碳原子数3〜7的任意取代环烷基等。
    • 8. 发明申请
    • MELT CONTAINER
    • US20130092589A1
    • 2013-04-18
    • US13521745
    • 2010-12-16
    • Shuichi Ohkubo
    • Shuichi Ohkubo
    • B65D1/40
    • B65D1/40C04B35/18C04B35/565C04B2235/3217C04B2235/3418C04B2235/3826C04B2235/77C04B2235/96C04B2235/9607C04B2235/9676F27B14/00F27B14/08F27D1/0006
    • An object of the invention is to provide a container for holding a melt of a metal and/or a melt of a metal salt, in which a melt container allows keeping a small amount of heat radiation of the melt, suppressing penetration of the melt and development of breakage or cracking to the minimum, holding the melt suitably, and also preventing the melt from impurity contamination. The melt container of the invention is a container for holding the melt of the metal and/or the melt of the metal salt, and has, sequentially from inside of the container, a first layer constituted of a refractory having an apparent porosity of 12% or less, a second layer constituted of a refractory having a thermal conductivity (at 800° C.) of 4 W/m·K or less, and a third layer constituted of a refractory having a higher thermal conductivity than thermal conductivity of the second layer.
    • 本发明的目的是提供一种用于保持金属和/或金属盐的熔体的熔体的容器,其中熔体容器允许保持少量的熔体的热辐射,从而抑制熔体的渗透, 破裂或破裂发展至少,适当地保持熔体,并且还防止熔体受杂质污染。 本发明的熔融容器是用于保持金属和/或金属盐的熔体的熔体的容器,并且从容器的内部依次具有由表观孔隙率为12%的耐火材料构成的第一层, 或更低的第二层,由具有4W / m·K以下的导热性(800℃)的耐火材料构成的第二层,以及由耐热性构成的第三层,该耐火材料具有比第二 层。