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    • 2. 发明授权
    • Electromagnetic vibratory microplate shaker
    • 电磁振动微孔板振动筛
    • US06508582B2
    • 2003-01-21
    • US09745884
    • 2000-12-21
    • Mitchell A. Friedman
    • Mitchell A. Friedman
    • B01F1100
    • B01F11/0034B01F11/0008B01F2215/0037C12M27/16
    • An electromagnetic vibratory microplate shaker is disclosed of simplified design and improved mixing capability over previously known microplate shaker devices, comprising an electromagnetic drive assembly mounted within a rigid base and operatively connected to a microplate support tray. The support tray is in turn supported from below by a plurality of leaf springs which are tilted approximately 20° from vertical. During operation, an electromagnet is rapidly energized and de-energized causing an armature of the drive assembly to be pulled in and released up to 7,200 times per minute, in turn imparting a reciprocating vibration to the support platform and the microplates held thereon. Such a vibration causes eddy currents to be created within the individual microplate wells which have both horizontal and vertical components, thus ensuring thorough mixing of the contents of each microplate well irrespective of the diameter of the well, while keeping suspended solids truly suspended during the mixing cycle.
    • 公开了一种电磁振动微孔板振荡器,其简化了设计并提高了混合能力,超过了先前已知的微板振动器装置,其包括安装在刚性基座内并可操作地连接到微板支撑盘的电磁驱动组件。 支撑托盘又从下方被多个从垂直方向倾斜约20°的板簧支撑。 在操作期间,电磁体被快速通电并断电,致使驱动组件的电枢被拉入并且每分钟释放高达7200次,从而对支撑平台和保持在其上的微板进行往复振动。 这种振动会导致在单个微板孔内产生涡流,这些微波孔具有水平和垂直分量,从而确保每个微孔板的内容物充分混合,而与孔的直径无关,同时保持悬浮固体在混合期间真正悬浮 周期。
    • 3. 发明授权
    • Microplate cover seal applicator
    • 微孔板盖密封贴片机
    • US06408595B1
    • 2002-06-25
    • US09703462
    • 2000-11-01
    • Mitchell A. Friedman
    • Mitchell A. Friedman
    • B65B728
    • B65B51/148B65B7/2878
    • A microplate cover seal applicator comprising a downwardly spring-biased roller mounted in a pivotal arm which pivots the roller into and out of operative contact with the top face of a microplate. The lower face of the microplate is seated in a well formed in a horizontally moveable platen which is supported on a table-top frame. The platen is manipulated by a rotary handle to repetitively translate the platen in a horizontal forwards and back direction. Suction cups are provided at the base of the frame for temporarily affixing the frame to a work surface, such as a table top surface.
    • 一种微孔板盖密封施加器,其包括安装在枢转臂中的向下弹簧偏置的辊,该枢转臂将辊转动进入和离开与微板的顶面的操作接触。 微板的下表面位于形成在水平移动的压板中的井中,该压板被支撑在桌面框架上。 压板由旋转手柄操纵,以在水平的前后方向上重复地平移压板。 抽吸杯设置在框架的基部,用于临时将框架固定在诸如台面的工作表面上。
    • 5. 发明授权
    • Dispensing valve for fluids
    • 液体分配阀
    • US06742680B2
    • 2004-06-01
    • US10314751
    • 2002-12-09
    • Mitchell A. Friedman
    • Mitchell A. Friedman
    • B67D300
    • B67D3/043B65D47/248
    • A dispensing valve for fluids is disclosed which provides for ease of use by requiring only a minimal force exerted on the valve actuator to maintain the valve in an open position. A resilient valve actuator having the characteristics of a nonlinear spring is provided at an actuator end of the valve body and operatively connected to a plunger; with the opposite end of the plunger mounting a resilient valve seal that serves to pen and close a plurality of port openings. The valve may be manufactured with a variety of port configurations to provide for the dispensing of fluids of varying viscosities. The valve body and actuator are formed to allow the dispensing valve to be sterilized through high levels of radiation and through high temperature steam and chemical sterilization processes without degrading the valve structure or operation.
    • 公开了用于流体的分配阀,其通过仅需要施加在阀致动器上的最小的力将阀保持在打开位置而易于使用。 具有非线性弹簧特性的弹性阀致动器设置在阀体的致动器端部并且可操作地连接到柱塞; 柱塞的另一端安装弹性阀密封件,其用于笔和闭合多个端口开口。 阀可以用各种端口构造来制造,以提供不同粘度的流体的分配。 阀体和致动器形成为允许分配阀通过高水平的辐射和通过高温蒸汽和化学灭菌过程而消毒,而不会降低阀门结构或操作。
    • 8. 发明授权
    • Vertical electromagnetic shaker for biological and chemical specimens
    • US06659637B2
    • 2003-12-09
    • US09969883
    • 2001-10-03
    • Mitchell A. Friedman
    • Mitchell A. Friedman
    • B01F1100
    • B01F11/0034B01F11/0022B01F15/00753C12M27/16
    • An electromagnetic vibratory microplate shaker is disclosed of simplified design and improved mixing capability over previously known microplate shaker devices, comprising an electromagnetic drive assembly mounted within a rigid base and operatively connected to a microplate support platform. The support platform is in turn supported by a plurality of horizontally arrayed leaf springs. During operation, an electromagnet is rapidly energized and de-energized causing an armature of the drive assembly to be pulled in and released up to 7,200 times per minute, in turn imparting a vertical reciprocating vibration to the support platform and the microplates or multi-tube racks held thereon. Means are provided for adjusting the amplitude of the vibration as necessary to enable the entire volume of liquid within each microplate well or tube to be vertically displaced within the well or tube during each vibration cycle, thus ensuring thorough mixing of the contents of each microplate well or tube irrespective of its diameter, while keeping suspended solids truly suspended during the mixing cycle. Also provided is a static indicia of amplitude of vibration fixedly mounted on the support platform to enable the user to determine the optimal vibrational amplitude to use for a particular series of microplates or multi-tube racks being vibrated.
    • 9. 发明申请
    • Drip resistant dispensing valve for fluids
    • 防滴漏阀用于流体
    • US20070181615A1
    • 2007-08-09
    • US11703939
    • 2007-02-08
    • Gary R. AllansonMitchell A. Friedman
    • Gary R. AllansonMitchell A. Friedman
    • B67D3/00F16K31/00
    • B65D47/248F16K23/00
    • A drip resistant dispensing valve for fluids is disclosed, which provides a dispensing outlet configured to minimize the tendency for fluid to drip from the valve following a dispensing operation. The dispensing outlet exhibits curved interior surfaces and a curved outlet face construction; the face situated a distance away from the valve body. Such construction assists in minimizing the retention of fluid on the surfaces of the dispensing outlet, and migration of the fluid to surfaces outside of the dispensing outlet that could tend to promote growth of biological contaminates and/or provide additional surfaces that could pool fluid following a dispensing operation and thereafter drip from the valve. A shell is provided around the dispensing outlet to assist in avoiding contamination of the valve and of the fluid being dispensed through the valve, and to aid in positioning a receptacle for receiving fluid from the dispensing valve.
    • 公开了一种用于流体的防滴水分配阀,其提供分配出口,其配置成使得在分配操作之后流体从阀门滴落的趋势最小化。 分配出口呈现弯曲的内表面和弯曲出口面结构; 该表面离开阀体一定距离。 这样的结构有助于使流体在分配出口的表面上的保留最小化,以及将流体迁移到分配出口外部的表面,其可能倾向于促进生物污染物的生长和/或提供可以在 分配操作,然后从阀门滴落。 壳体围绕分配出口设置,以帮助避免阀和通过阀分配的流体的污染,并且有助于定位用于从分配阀接收流体的容器。
    • 10. 发明授权
    • Multidirectional mixing of fluid samples
    • 流体样品的多方向混合
    • US07210843B2
    • 2007-05-01
    • US11583228
    • 2006-10-19
    • Mitchell A. Friedman
    • Mitchell A. Friedman
    • B01F11/00
    • B01F11/0034B01F2215/0037
    • A method of mixing fluid samples using an electromagnetic multidirectional shaker is provided. The shaker has a first electromagnet driving a first support panel in a first direction, and a second electromagnet driving a second support panel in a second direction. The first electromagnet is affixed to a base and is operatively attached to the first support panel which is suspended from the base via one or more first spring members. The first spring members are configured to bias the first support panel to an at-rest position after it has been displaced by the first electromagnet. The second support panel is in turn supported above the first support panel by one or more second spring members. The second electromagnet is affixed to the first support panel, and is operatively attached to the second support panel. The second spring members are configured to bias the second support panel to an at-rest position after it has been displaced by the second electromagnet.
    • 提供了一种使用电磁多向振动器混合流体样品的方法。 振动器具有沿第一方向驱动第一支撑板的第一电磁体和在第二方向上驱动第二支撑板的第二电磁体。 第一电磁体固定在基座上,并可操作地连接到第一支撑板上,第一支撑板通过一个或多个第一弹簧构件从基座悬挂。 第一弹簧构件构造成在第一弹簧构件被第一电磁体移位之后将第一支撑面板偏置到静止位置。 第二支撑面板又通过一个或多个第二弹簧构件支撑在第一支撑面板的上方。 第二电磁铁被固定到第一支撑面板上,并且可操作地附接到第二支撑面板。 第二弹簧构件构造成在第二弹簧构件已经被第二电磁体移位之后将第二支撑板偏压到静止位置。