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1. 发明授权

US07329879B2 Apparatus for manipulation of ions and methods of making apparatus 失效
标题翻译：用于操作离子的装置和制造装置的方法
公开(公告)号：US07329879B2
公开(公告)日：2008-02-12
申请号：US11064036
申请日：2005-02-22
申请人： Jeffrey T. Kernan , Edward C. Cirimele , Mingda Wang , J. Gerson Goldberg , James L. Bertsch
发明人： Jeffrey T. Kernan , Edward C. Cirimele , Mingda Wang , J. Gerson Goldberg , James L. Bertsch
IPC分类号： H01J49/42
CPC分类号： H01J49/063 , H01J49/4215 , H01J49/4225 , H01J49/4255
摘要： A device for manipulating ions which includes a perforated folder of electrically conductive material, a first electrode fixed to the holder and a second electrode extending parallel to the first electrode and spaced from the first electrode and holder. The second electrode is connected to the holder through a rigid support of electrically insulated material.
摘要翻译：一种用于操作离子的装置，其包括导电材料的穿孔的夹具，固定到保持器的第一电极和平行于第一电极延伸并与第一电极和保持器间隔开的第二电极。第二电极通过电绝缘材料的刚性支撑件连接到保持器。

2. 发明授权

US07259379B2 On-axis electron impact ion source 失效
标题翻译：轴上电子冲击离子源
公开(公告)号：US07259379B2
公开(公告)日：2007-08-21
申请号：US11271443
申请日：2005-11-09
申请人： Mingda Wang , Edward C. Cirimele
发明人： Mingda Wang , Edward C. Cirimele
IPC分类号： B01D59/44 , H01J27/00 , H01J49/26
CPC分类号： H01J49/147 , H01J49/063
摘要： An electron impact ion source includes an ionization chamber in which a first rf multipole field can be generated and an ion guide positioned downstream from the ionization chamber in which a second rf multipole field can be generated wherein electrons are injected into the ionization chamber along the axis (on-axis) to ionize an analyte sample provided to the ionization chamber.
摘要翻译：电子碰撞离子源包括其中可以产生第一rf多极场的电离室和位于电离室下游的离子导向器，其中可以产生第二射频多极场，其中电子沿着轴线注入电离室（轴上）离子化提供给电离室的分析物样品。

3. 发明授权

US06998622B1 On-axis electron impact ion source 失效
公开(公告)号：US06998622B1
公开(公告)日：2006-02-14
申请号：US10992191
申请日：2004-11-17
申请人： Mingda Wang , Edward C. Cirimele
发明人： Mingda Wang , Edward C. Cirimele
IPC分类号： H01J49/00 , B01D59/44
CPC分类号： H01J49/147 , H01J49/063
摘要： An electron impact ion source includes an ionization chamber in which a first rf multipole field can be generated and an ion guide positioned downstream from the ionization chamber in which a second rf multipole field can be generated wherein electrons are injected into the ionization chamber along the axis (on-axis) to ionize an analyte sample provided to the ionization chamber.

4. 发明授权

US06723986B2 Apparatus for manipulation of ions and methods of making apparatus 失效
标题翻译：用于操作离子的装置和制造装置的方法
公开(公告)号：US06723986B2
公开(公告)日：2004-04-20
申请号：US10027333
申请日：2002-03-15
申请人： Jeffrey T. Kernan , Edward C. Cirimele , Mingda Wang
发明人： Jeffrey T. Kernan , Edward C. Cirimele , Mingda Wang
IPC分类号： B01D5944
CPC分类号： H01J49/063 , H01J49/4215 , H01J49/4225 , H01J49/4255
摘要： A device for manipulating ions which includes a perforated folder of electrically conducted material, a first electrode fixed to the holder and a second electrode extending parallel to the first electrode and spaced from the first electrode and holder. The second electrode is connected to the holder through a rigid support of electrically insulated material.
摘要翻译：一种用于操作离子的装置，其包括导电材料的穿孔夹具，固定到保持器的第一电极和平行于第一电极延伸并与第一电极和保持器间隔开的第二电极。第二电极通过电绝缘材料的刚性支撑件连接到保持器。

5. 发明授权

US07501623B2 Two-dimensional electrode constructions for ion processing 有权
标题翻译：用于离子处理的二维电极结构
公开(公告)号：US07501623B2
公开(公告)日：2009-03-10
申请号：US11342485
申请日：2006-01-30
申请人： Roger Tong , Mingda Wang , Gregory J. Wells
发明人： Roger Tong , Mingda Wang , Gregory J. Wells
IPC分类号： H01J49/42
CPC分类号： H01J49/423 , H01J49/4225
摘要： An electrode for use in a device such as an ion trap has an axial length extending generally in the direction of a central axis from a first axial end to a second axial end, and an inside surface. The inside surface includes a surface profile that is uniform from the first axial end to the second axial end, or at least is uniform for a uniform section length along the axial direction. The electrode may include an elongated surface feature such as a groove that extends for at least the uniform section length. An aperture may communicate with the groove. The electrode may be axially segmented into regions. Gaps between the regions may be oriented at an angle relative to a plane orthogonal to the central axis. The electrode may be one of several electrodes arranged as an electrode structure coaxially disposed about an elongated interior space.
摘要翻译：用于诸如离子阱的装置的电极具有从第一轴向端部到第二轴向端部以及内表面大致沿中心轴线的方向延伸的轴向长度。内表面包括从第一轴向端到第二轴向端均匀的表面轮廓，或者至少沿着轴向方向具有均匀的截面长度是均匀的。电极可以包括细长的表面特征，例如延伸至少均匀的截面长度的凹槽。孔可以与凹槽连通。电极可以轴向分段成区域。区域之间的间隙可以相对于与中心轴线正交的平面成一定角度。电极可以是布置成围绕细长内部空间同轴设置的电极结构的多个电极之一。

6. 发明申请

US20070176095A1 Two-dimensional electrode constructions for ion processing 有权
标题翻译：用于离子处理的二维电极结构
公开(公告)号：US20070176095A1
公开(公告)日：2007-08-02
申请号：US11342485
申请日：2006-01-30
申请人： Roger Tong , Mingda Wang , Gregory Wells
发明人： Roger Tong , Mingda Wang , Gregory Wells
IPC分类号： H01J49/42
CPC分类号： H01J49/423 , H01J49/4225
摘要： An electrode for use in a device such as an ion trap has an axial length extending generally in the direction of a central axis from a first axial end to a second axial end, and an inside surface. The inside surface includes a surface profile that is uniform from the first axial end to the second axial end, or at least is uniform for a uniform section length along the axial direction. The electrode may include an elongated surface feature such as a groove that extends for at least the uniform section length. An aperture may communicate with the groove. The electrode may be axially segmented into regions. Gaps between the regions may be oriented at an angle relative to a plane orthogonal to the central axis. The electrode may be one of several electrodes arranged as an electrode structure coaxially disposed about an elongated interior space.
摘要翻译：用于诸如离子阱的装置的电极具有从第一轴向端部到第二轴向端部以及内表面大致沿中心轴线的方向延伸的轴向长度。内表面包括从第一轴向端到第二轴向端均匀的表面轮廓，或者至少沿着轴向方向具有均匀的截面长度是均匀的。电极可以包括细长的表面特征，例如延伸至少均匀的截面长度的凹槽。孔可以与凹槽连通。电极可以轴向分段成区域。区域之间的间隙可以相对于与中心轴线正交的平面成一定角度。电极可以是布置成围绕细长内部空间同轴设置的电极结构的多个电极之一。

7. 发明申请

US20050167584A1 Apparatus for manipulation of ions and methods of making apparatus 失效
标题翻译：用于操作离子的装置和制造装置的方法
公开(公告)号：US20050167584A1
公开(公告)日：2005-08-04
申请号：US11064036
申请日：2005-02-22
申请人： Jeffrey Kernan , Edward Cirimele , Mingda Wang
发明人： Jeffrey Kernan , Edward Cirimele , Mingda Wang
IPC分类号： H01J49/42 , B01D59/44
CPC分类号： H01J49/063 , H01J49/4215 , H01J49/4225 , H01J49/4255
摘要： A device for manipulating ions which includes a perforated folder of electrically conductive material, a first electrode fixed to the holder and a second electrode extending parallel to the first electrode and spaced from the first electrode and holder. The second electrode is connected to the holder through a rigid support of electrically insulated material.
摘要翻译：一种用于操作离子的装置，其包括导电材料的穿孔的夹具，固定到保持器的第一电极和平行于第一电极延伸并与第一电极和保持器间隔开的第二电极。第二电极通过电绝缘材料的刚性支撑件连接到保持器。

8. 发明授权

US5714755A Mass scanning method using an ion trap mass spectrometer 失效
标题翻译：使用离子阱质谱仪的质谱扫描方法
公开(公告)号：US5714755A
公开(公告)日：1998-02-03
申请号：US609364
申请日：1996-03-01
申请人： Gregory J. Wells , Mingda Wang , Edward G. Marquette
发明人： Gregory J. Wells , Mingda Wang , Edward G. Marquette
IPC分类号： G01N27/62 , H01J49/04 , H01J49/42 , B01D59/44 , H01J49/00
CPC分类号： H01J49/424 , H01J49/429
摘要： An improved method of using an ion trap mass spectrometer is disclosed. According to the method an asymmetrical trapping field is applied to the trap. Preferably, the asymmetrical trapping field comprises a quadrupole field and a dipole field having the same frequency. In addition, higher order trapping field components, such as hexapole or octopole fields, may also be included, and the electrodes of the ion trap can be shaped to introduce such higher order field components. The effect of the asymmetrical trapping field of the present invention is to cause the center of the trapping field to be displaced from the mechanical center of the ion trap. A supplemental quadrupole field is then applied to the ion trap, the center of the supplemental quadrupole field being located at the mechanical center of the trap, i.e., it is displaced from the center of the trapping field. The supplement quadrupole field and the trapping field may be viewed as forming one combined field which acts upon the ions in the trap. The combined field is then scanned to cause ions of differing masses to be resonantly ejected from the ion trap in sequential mass order. Preferably, the combined field is scanned by scanning the voltage of the trapping field. Preferably, the supplemental field is set to have a frequency which is two-thirds of the trapping field frequency and is phase locked with the trapping field frequency.
摘要翻译：公开了使用离子阱质谱仪的改进方法。根据该方法，将不对称捕获场应用于陷阱。优选地，不对称捕获场包括具有相同频率的四极场和偶极场。此外，还可以包括诸如六极或八极场的较高阶捕获场分量，并且离子阱的电极可被成形为引入这种较高阶场分量。本发明的不对称捕获场的作用是使捕集场的中心从离子阱的机械中心位移。然后将补充的四极场施加到离子阱，补充四极场的中心位于阱的机械中心，即其从俘获场的中心位移。补充四极场和俘获场可以被视为形成一个组合场，其作用在阱中的离子上。然后扫描组合场，使不同质量的离子以顺序的质量顺序从离子阱共振地喷出。优选地，通过扫描捕获场的电压来扫描组合场。优选地，补充场被设置为具有捕获场频率的三分之二的频率并且与捕获场频率锁相。

9. 发明授权

US5291017A Ion trap mass spectrometer method and apparatus for improved sensitivity 失效
标题翻译：离子阱质谱仪方法和设备提高灵敏度
公开(公告)号：US5291017A
公开(公告)日：1994-03-01
申请号：US9604
申请日：1993-01-27
申请人： Mingda Wang , Edward G. Marquette
发明人： Mingda Wang , Edward G. Marquette
IPC分类号： H01J49/42 , H01V49/42
CPC分类号： H01J49/424 , H01J49/4275 , H01J49/429
摘要： An ion trap mass spectrometer system providing superposition of an AC dipole and/or monopole field on the quadrupole field to provide one preferential ejection direction.
摘要翻译：一种离子阱质谱仪系统，其在四极场上提供AC偶极子和/或单极场的叠加以提供一个优先的射出方向。

10. 发明授权

US07564029B2 Sample ionization at above-vacuum pressures 有权
公开(公告)号：US07564029B2
公开(公告)日：2009-07-21
申请号：US11893308
申请日：2007-08-15
申请人： Mingda Wang , Charles A. Fancher , Felician Muntean , Urs Steiner
发明人： Mingda Wang , Charles A. Fancher , Felician Muntean , Urs Steiner
IPC分类号： H01J49/26
CPC分类号： H01J49/0477 , H01J49/0404 , H01J49/044
摘要： Sample material ionized in a sample receiving chamber is flowed into a sample conduit. Drying gas may also flow into the sample conduit and may be heated. The pressure and length of the sample conduit may be provided according to the product 50 or greater Torr−cm. The sample conduit may include a turn. The sample conduit may lead to an ion extraction chamber at which a sampling orifice may lead to a mass spectrometer. The diameter of the sample conduit may be larger than the diameter of the sampling orifice. An electrical field may be applied in the ion extraction chamber to slow incoming ions. A voltage jump may be applied to the sample conduit.

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